{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:46:57Z","timestamp":1782496017371,"version":"3.54.5"},"reference-count":40,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005375","name":"Latvian Council of Science","doi-asserted-by":"publisher","award":["lzp-2020\/1-0422"],"award-info":[{"award-number":["lzp-2020\/1-0422"]}],"id":[{"id":"10.13039\/501100005375","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Although not major crops, Cornaceae species, the dogwood family, are common in most continents and used primarily as ornamental crops, though some are used for food as well. In the present study, tocochromanol\u2013tocopherol (T) and tocotrienol (T3)\u2013contents were analyzed in the seeds of twenty-four Cornus species belonging to six Cornus subgenera. Given the substantial number of samples included in this study, we applied a fast extraction protocol using an ethanol and ultrasound treatment and systematically compared its performance with that of a conventional alkaline saponification method. Total tocochromanol content ranged from 0.78 to 21.63 mg 100 g\u22121 dry weight (dw) seeds in C. kousa and C. controversa, respectively. The highest mean total tocochromanol content was (16.70 \u00b1 5.28 mg 100 g\u22121 dw), followed by C. nuttallii (12.96 mg 100 g\u22121 dw) and C. sanguinea (9.10 \u00b1 2.47 mg 100 g\u22121 dw). The major tocochromanols in the seeds were \u03b3-T3 (up to 93% in C. rugosa), \u03b1-T (up to 98% in C. mas) and \u03b3-T (up to 60% in C. controversa). Tocochromanol composition was strongly subgenus-dependent. The applied sustainable solvent\u2013ethanol and ultrasound-treatment approach for the extraction of tocochromanols demonstrated the suitability of this method for screening daily Cornus species seed samples and potential extraction.<\/jats:p>","DOI":"10.3390\/molecules31030519","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T15:38:12Z","timestamp":1770046692000},"page":"519","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Screening of Tocopherol and Tocotrienol Diversity in Cornus Species Seeds Using a Sustainable Extraction Protocol"],"prefix":"10.3390","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8083-8676","authenticated-orcid":false,"given":"Danija","family":"Lazdi\u0146a","sequence":"first","affiliation":[{"name":"Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5764-0143","authenticated-orcid":false,"given":"Inga","family":"Mi\u0161ina","sequence":"additional","affiliation":[{"name":"Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1281-8200","authenticated-orcid":false,"given":"Krists","family":"Dukurs","sequence":"additional","affiliation":[{"name":"Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3908-2296","authenticated-orcid":false,"given":"Pawe\u0142","family":"G\u00f3rna\u015b","sequence":"additional","affiliation":[{"name":"Institute of Horticulture, Graudu 1, LV-3701 Dobele, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"key":"ref_1","unstructured":"Royal Botanic Gardens, Kew (2025, December 30). 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