{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:08:37Z","timestamp":1777914517099,"version":"3.51.4"},"reference-count":42,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>A comparative analysis of pentacyclic triterpenoids (ursolic acid and oleanolic acid) in the aerial parts of eleven Epilobium species was performed using high-performance liquid chromatography (HPLC) results. Samples for the analysis were collected from various regions in Ukraine, Poland and Lithuania. Oleanolic acid and ursolic acid were identified and quantified in nine of the species (E. angustifolium, E. montanum, E. collinum, E. roseum, E. palustre, E. tetragonum, E. obscurum, E. nervosum, and E. nutans). However, neither compound was detected in E. parviflorum or E. hirsutum from any collection site, indicating notable chemotaxonomic divergence within the genus. The quantity of ursolic acid in the analysed samples ranged from 20.27 \u00b1 0.49 to 74.84 \u00b1 2.24 mg\/100 g dry weight, consistently exceeding that of oleanolic acid (2.03 \u00b1 0.05 to 32.09 \u00b1 0.73 mg\/100 g). The highest total triterpenoid content was observed in E. tetragonum. These findings emphasise the importance of oleanolic and ursolic acids as auxiliary chemotaxonomic markers for Epilobium species. Given the well-documented antiproliferative and antiviral activities of these triterpenoids, the present results also suggest that several under-explored Epilobium species could be a promising source of bioactive compounds for further pharmacological research, particularly regarding prostate cancer and viral infections.<\/jats:p>","DOI":"10.3390\/molecules31091510","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T16:54:07Z","timestamp":1777654447000},"page":"1510","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Comparative Analysis of Ursolic and Oleanolic Acids in Eleven Epilobium Species"],"prefix":"10.3390","volume":"31","author":[{"given":"Kateryna","family":"Uminska","sequence":"first","affiliation":[{"name":"Zhytomyr Basic Pharmaceutical Professional College, Chudnivska Str. 99, 10005 Zhytomyr, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6230-5924","authenticated-orcid":false,"given":"Zigmantas","family":"Gud\u017einskas","sequence":"additional","affiliation":[{"name":"State Scientific Research Institute Nature Research Centre, Laboratory of Flora and Geobotany, LT-08412 Vilnius, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8794-8010","authenticated-orcid":false,"given":"Victoriya","family":"Georgiyants","sequence":"additional","affiliation":[{"name":"Pharmaceutical Chemistry Department, National University of Pharmacy, 61168 Kharkiv, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liudas","family":"Ivanauskas","sequence":"additional","affiliation":[{"name":"Department of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6934-9524","authenticated-orcid":false,"given":"Mindaugas","family":"Marksa","sequence":"additional","affiliation":[{"name":"Department of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0266-827X","authenticated-orcid":false,"given":"Viktoriia","family":"Volochai","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, National University of Pharmacy, 61002 Kharkiv, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alla","family":"Kozurak","sequence":"additional","affiliation":[{"name":"Carpathian Biosphere Reserve, 90600 Rakhiv, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3822-8409","authenticated-orcid":false,"given":"Olha","family":"Mykhailenko","sequence":"additional","affiliation":[{"name":"Pharmaceutical Chemistry Department, National University of Pharmacy, 61168 Kharkiv, Ukraine"},{"name":"Pharmacognosy and Phytotherapy Group, UCL School of Pharmacy, London WC1N 1AX, UK"},{"name":"Department of Pharmaceutical Biology, Kiel University, 24118 Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"ref_1","unstructured":"Wagner, W.L., Hoch, P.C., and Raven, P.H. 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