{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T21:29:32Z","timestamp":1785446972627,"version":"3.56.0"},"reference-count":156,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Coordena\u00e7\u00e3o de Aperfeicoamento de Pessoal de N\u00edvel Superior\u2014Brasil","award":["001"],"award-info":[{"award-number":["001"]}]},{"award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"https:\/\/ror.org\/00x0ma614","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Significant amounts of food waste come from fruit processing, causing economic and environmental impacts. The waste generated is a valuable source of compounds due to its concentration of nutrients, such as dietary fiber, vitamins, minerals, lipids with mono- and polyunsaturated fatty acids, and bioactive compounds. Despite the nutritional and functional qualities of the waste, it is still commonly discarded and underutilized, demonstrating the importance of studying it. The selected fruits described in this study are widely consumed by various populations around the world and are used at an industrial scale. The objective of this review is to discuss the use of seeds from grapes, passion fruit, melon, watermelon, papaya, guava, raspberry, and pomegranate and their benefits for human consumption. The seeds stand out for the possibility of oil extraction, creating a sustainable and healthy mode of production. Due to their nutritional composition rich in polyunsaturated fatty acids, they have been shown to be beneficial to health, promoting development, strengthening the immune system, and promoting the growth and maintenance of cell membranes, cardiovascular benefits, and antimicrobial and antioxidant activity, in addition to innovation in the cosmetics sector and applicability as biofuel. Therefore, the exploitation of this type of by-product shows promise in the search for alternative sources of vegetable oils and bioactive compounds with high added nutritional value and potential nutraceutical application, helping to increase the value of food waste and thus contributing to a better use of plant resources.<\/jats:p>","DOI":"10.3390\/molecules31101626","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T12:33:37Z","timestamp":1778589217000},"page":"1626","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fruit Seeds with Functional Applications: From Food Waste to Potential Uses"],"prefix":"10.3390","volume":"31","author":[{"given":"Dayane St\u00e9phanie","family":"Fernandes","sequence":"first","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1717-1498","authenticated-orcid":false,"given":"Geovana Miyashiro","family":"Ferreira Neto","sequence":"additional","affiliation":[{"name":"Pharmaceutical Science, Food and Nutrition Faculty, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giullia Gabrielli","family":"Galiciani","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6965-6639","authenticated-orcid":false,"given":"Ros\u00e2ngela dos Santos","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidiani Figueiredo","family":"Santana","sequence":"additional","affiliation":[{"name":"Medical School, State University of Mato Grosso do Sul (UEMS), Campo Grande 79115-898, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1115-4083","authenticated-orcid":false,"given":"Priscila Aiko","family":"Hiane","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valter Arag\u00e3o","family":"do Nascimento","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnildo","family":"Pott","sequence":"additional","affiliation":[{"name":"Laboratory of Botany, Institute of Biosciences, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita de C\u00e1ssia Avellaneda","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5813-6088","authenticated-orcid":false,"given":"Karine de C\u00e1ssia","family":"Freitas","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Chaouch, M.A., and Benvenuti, S. 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