{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:58:50Z","timestamp":1787029130190,"version":"build-2736575974"},"reference-count":52,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T00:00:00Z","timestamp":1786838400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21766004"],"award-info":[{"award-number":["21766004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"award":["21766004"],"award-info":[{"award-number":["21766004"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"publisher"}]},{"name":"Innovation Project of Guangxi Minzu University Graduate Education","award":["gxun-chxb202204"],"award-info":[{"award-number":["gxun-chxb202204"]}]},{"award":["gxun-chxb202204"],"award-info":[{"award-number":["gxun-chxb202204"]}],"id":[{"id":"https:\/\/ror.org\/0495efn48","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Efficient and sustainable isolation of cellulose from sugarcane tops (ST), a major sub-fraction of sugarcane trash, is of great significance for the high-value valorization of cellulose and its subsequent conversion into substrates for biomaterials. This study introduces a novel two-step cascade process under mild conditions, which integrates two treatments: a green multi-functional depolymerizing agent (MDA) treatment and the alkaline hydrogen peroxide (AHP) treatment. This sequential strategy is designed to selectively solubilize hemicellulose and lignin, respectively, ultimately yielding cellulose from ST. To assess extraction efficacy, four MDA treatment durations (0\u20133 h) were systematically investigated. The quality of the extracted cellulose was evaluated through lignocellulosic composition analysis, surface morphology, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA). Results demonstrate that the MDA treatment effectively disrupted ST\u2019s recalcitrant structure, facilitating selective hemicellulose enrichment in deionized water and lignin dissolution in 1% (w\/v) AHP. Notably, cellulose pretreated for 2 h exhibited preferred properties, including high purity (85.82%), a retention rate of 85.33%, preservation of the cellulose I crystalline polymorph (crystallinity index, CrI = 69.11%), and excellent thermal stability (maximum decomposition temperature, Tmax = 344.48 \u00b0C). The preserved structural integrity suggests the potential suitability of the extracted cellulose as a promising feedstock for polymer composite applications.<\/jats:p>","DOI":"10.3390\/molecules31162860","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T10:04:36Z","timestamp":1786961076000},"page":"2860","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Two-Step Cascade Process for Efficient Isolation of Cellulose from Sugarcane Trash"],"prefix":"10.3390","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-8971-8264","authenticated-orcid":false,"given":"Jian","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi Minzu University, Nanning 530006, China"},{"name":"Institute of Traditional Chinese and Zhuang-Yao Ethnic Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang-Lin","family":"Yin","sequence":"additional","affiliation":[{"name":"Institute of Traditional Chinese and Zhuang-Yao Ethnic Medicine, Guangxi University of Chinese Medicine, Nanning 530200, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu-Yi","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao-Yu","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Ting","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Xia","family":"He","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang-Yi","family":"Li","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ri-Hui","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi Minzu University, Nanning 530006, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1452-0264","authenticated-orcid":false,"given":"Da-Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"105896","DOI":"10.1016\/j.biombioe.2020.105896","article-title":"Sugarcane straw as a potential second generation feedstock for biorefinery and white biotechnology applications","volume":"144","author":"Aguiar","year":"2021","journal-title":"Biomass Bioenergy"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jclepro.2019.01.223","article-title":"Approaches for converting sugarcane trash, a promising agro residue, into pulp and paper using soda pulping and elemental chlorine-free bleaching","volume":"217","author":"Bhardwaj","year":"2019","journal-title":"J. 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