{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T04:18:04Z","timestamp":1787890684118,"version":"build-2784847793"},"reference-count":35,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Orl\u00e9ans M\u00e9tropole","award":["001"],"award-info":[{"award-number":["001"]}]},{"name":"Mageline Company","award":["001"],"award-info":[{"award-number":["001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Skin aging is a major consideration regarding cosmetic skin care. The cosmetic field is seeking new active ingredients able to slow down the appearance of signs of age. Some lichens and more specifically the genus Cetraria s. str. presents an interest as a source of active molecules because it is already being used in traditional and modern medicines. To better evaluate the potential of C. islandica as anti-aging skin care, we investigated some key aspects to protect skin from external aggression and to avoid skin alteration, which would exacerbate signs of age. Among them, our results reveal (i) antioxidant capacities; (ii) anti-inflammatory properties on human keratinocytes once stimulated, as shown by a decrease in IL-6, IL-8, CXCL9, CXCL10, and CCL5; (iii) a downregulation of MT1-MMP, which corresponds to decreased tissue remodeling; and (iv) an inhibition of human tyrosinase, which could correct the appearance over time of age-related skin spots. Altogether, these results highlight the potential use of C. islandica in anti-aging skin care.<\/jats:p>","DOI":"10.3390\/molecules31172988","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:59:57Z","timestamp":1787749197000},"page":"2988","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["In Vitro Anti-Aging Properties of a Cetraria islandica Extract: Interest for Skin Care Cosmetics"],"prefix":"10.3390","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3894-8056","authenticated-orcid":false,"given":"Anthony","family":"Groso","sequence":"first","affiliation":[{"name":"Cosmetology Department, AgroParisTech, 45100 Orl\u00e9ans, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Jabet","sequence":"additional","affiliation":[{"name":"Cosmetology Department, AgroParisTech, 45100 Orl\u00e9ans, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Fan","sequence":"additional","affiliation":[{"name":"Research & Development Center, Mageline Biology Tech Co., Ltd., Wuhan 430060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Hua","sequence":"additional","affiliation":[{"name":"Research & Development Center, Mageline Biology Tech Co., Ltd., Wuhan 430060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Yawen","sequence":"additional","affiliation":[{"name":"Research & Development Center, Mageline Biology Tech Co., Ltd., Wuhan 430060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo","family":"Miao","sequence":"additional","affiliation":[{"name":"Research & Development Center, Mageline Biology Tech Co., Ltd., Wuhan 430060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7296-3736","authenticated-orcid":false,"given":"Richard","family":"Daniellou","sequence":"additional","affiliation":[{"name":"Cosmetology Department, AgroParisTech, 45100 Orl\u00e9ans, France"},{"name":"National Research Institute for Agriculture, Food and the Environment (INRAE), AgroParisTech, UMR Micalis, Universite Paris-Saclay, 78350 Jouy-en-Josas, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0355-563X","authenticated-orcid":false,"given":"Guillaume","family":"Collet","sequence":"additional","affiliation":[{"name":"Cosmetology Department, AgroParisTech, 45100 Orl\u00e9ans, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.clindermatol.2013.05.013","article-title":"Anti-Aging Cosmetics: Facts and Controversies","volume":"31","author":"Celem","year":"2013","journal-title":"Clin. 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