{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T14:11:02Z","timestamp":1789567862081,"version":"build-2803163510"},"reference-count":221,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Salvia (Lamiaceae) is Mexico\u2019s most diverse and widely distributed genus. It represents an important natural resource for the country, with approximately 310 species belonging to the subgenera Calosphace, Audibertia, and Heterosphace. Several of these species have been used in traditional Mexican medicine to treat various diseases. However, the main secondary metabolites as potential bioactive components have been poorly described. This review aims to identify the main chemical constituents of Mexican sages with abietane- and\/or clerodane-type diterpene structures, list those with documented biological properties, and analyze the distribution of secondary metabolites within the genus from a phylogenetic perspective. The research identified at least 406 diterpene chemical components in Mexican salvias; of these, 128 were abietanes and 278 were clerodanes. Interestingly, some possess a broad spectrum of biological activities, including antidiabetic, antioxidant, antihypertensive, antimicrobial, antinociceptive, anti-inflammatory, and cytotoxic effects, among the most cited. Analysis of the distribution of abietanes and clerodanes in Mexican salvias showed a marked difference in their occurrence, since abietanes are mainly found in the Audibertia subgenus and clerodanes are more evident in the Calosphace subgenus. This review provides chemical and pharmacological information on diterpene metabolites in Mexican Salvia species, supporting the relevance of studying these species for future research on their potential bioactivity as a source of new therapeutic alternatives.<\/jats:p>","DOI":"10.3390\/molecules31183287","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:50:27Z","timestamp":1789566627000},"page":"3287","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diterpenes with Abietane and Clerodane Skeletons from the Mexican Salvia Species as Potential Bioactive Compounds"],"prefix":"10.3390","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6354-4916","authenticated-orcid":false,"given":"Nancy","family":"Ortiz-Mendoza","sequence":"first","affiliation":[{"name":"Laboratorio de Productos Naturales, Departamento de Ecolog\u00eda y Recursos Naturales, Facultad de Ciencias, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico 04510, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1525-8966","authenticated-orcid":false,"given":"Iv\u00e1n J.","family":"Bazany-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Instituto de Qu\u00edmica, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico 04510, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3636-7416","authenticated-orcid":false,"given":"Martha J.","family":"Mart\u00ednez-Gordillo","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Comparada, Herbario de la Facultad de Ciencias, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico 04510, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco A.","family":"Basurto-Pe\u00f1a","sequence":"additional","affiliation":[{"name":"Jard\u00edn Bot\u00e1nico, Instituto de Biolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico 04510, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7056-4237","authenticated-orcid":false,"given":"Alejandro","family":"Dorazco-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Instituto de Qu\u00edmica, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico 04510, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3661-1076","authenticated-orcid":false,"given":"Itzi","family":"Fragoso-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Red de Biodiversidad y Sistem\u00e1tica, Instituto de Ecolog\u00eda A.C., Xalapa 91073, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4399-1508","authenticated-orcid":false,"given":"Mar\u00eda Eva","family":"Gonz\u00e1lez-Trujano","sequence":"additional","affiliation":[{"name":"Laboratorio de Neurofarmacolog\u00eda de Productos Naturales, Direcci\u00f3n de Investigaciones Biom\u00e9dicas en Salud Mental, Instituto Nacional de Psiquiatr\u00eda Ram\u00f3n de la Fuente Mu\u00f1iz, Ciudad de M\u00e9xico 14370, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4770-4174","authenticated-orcid":false,"given":"Emmanuel","family":"Mart\u00ednez Ambriz","sequence":"additional","affiliation":[{"name":"Red de Biodiversidad y Sistem\u00e1tica, Instituto de Ecolog\u00eda A.C., Xalapa 91073, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8577-7991","authenticated-orcid":false,"given":"Marcos","family":"Soto-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Posgrado en Bot\u00e1nica, Colegio de Postgraduados, Campus Montecillo, Texcoco 56264, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Aguirre-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Laboratorio de Productos Naturales, Departamento de Ecolog\u00eda y Recursos Naturales, Facultad de Ciencias, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico 04510, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"30","DOI":"10.7550\/rmb.30158","article-title":"G\u00e9neros de Lamiaceae de M\u00e9xico, diversidad y endemismo","volume":"84","author":"Montiel","year":"2013","journal-title":"Rev. Mex. Biodiver."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"780","DOI":"10.17129\/botsci.1871","article-title":"Lamiaceae de M\u00e9xico","volume":"95","author":"Zamudio","year":"2017","journal-title":"Bot. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.21829\/abm23.1993.675","article-title":"Revisi\u00f3n taxon\u00f3mica de Salvia secci\u00f3n Sigmoideae (Lamiaceae)","volume":"23","author":"Espejo","year":"1993","journal-title":"Acta Bot. Mex."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Ortiz-Mendoza, N., Aguirre-Hern\u00e1ndez, E., Fragoso-Mart\u00ednez, I., Gonz\u00e1lez-Trujano, M.E., Basurto-Pe\u00f1a, F.A., and Mart\u00ednez-Gordillo, M.J. (2022). A review on the ethnopharmacology and Phytochemistry of the neotropical sages (Salvia Subgenus Calosphace; Lamiaceae) emphasizing Mexican species. Front. Pharmacol., 13.","DOI":"10.3389\/fphar.2022.867892"},{"key":"ref_5","first-page":"19","article-title":"Usos medicinales de la familia Labiatae en Chiapas, M\u00e9xico","volume":"2","year":"2002","journal-title":"Etnobiolog\u00eda"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.jep.2012.12.035","article-title":"Medicinal plant complexes of Salvia subgenus Calosphace: An ethnobotanical study of new world sages","volume":"146","author":"Jenks","year":"2013","journal-title":"J. Ethnopharmacol."},{"key":"ref_7","first-page":"508","article-title":"Traditional medicinal plants used for the treatment of gastrointestinal diseases in Chiapas, M\u00e9xico","volume":"31","year":"2014","journal-title":"World Appl. Sci. J."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.jep.2013.11.032","article-title":"From local to global-Fifty years of research on Salvia divinorum","volume":"151","author":"Casselman","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"ref_9","first-page":"311","article-title":"Neo-clerodane dipertenoids from American Salvia species","volume":"29","author":"Esquivel","year":"1995","journal-title":"Recent Adv. Phytochem."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Esquivel, B., Bustos-Brito, C., S\u00e1nchez-Castellanos, M., Nieto-Camacho, A., Ram\u00edrez-Apan, T., Joseph-Nathan, P., and Quijano, L. (2017). Structure, absolute configuration, & antiproliferative activity of abietane & icetexane diterpenoids from Salvia ballotiflora. Molecules, 22.","DOI":"10.20944\/preprints201709.0164.v1"},{"key":"ref_11","first-page":"989","article-title":"Rearranged clerodane and abietane derived diterpenoids from American Salvia species","volume":"3","author":"Esquivel","year":"2008","journal-title":"Nat. Prod. Commun."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1021\/acs.jnatprod.8b00565","article-title":"Amarisolide F, an acylated diterpenoid glucoside and related terpenoids from Salvia amarissima","volume":"82","author":"Toscano","year":"2019","journal-title":"J. Nat. Prod."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s00606-017-1445-4","article-title":"Phylogeny of the neotropical sages (Salvia subg. Calosphace; Lamiaceae) and insights into pollinator and area shifts","volume":"304","author":"Salazar","year":"2018","journal-title":"Plant Syst. Evol."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Lara-Cabrera, S.I., Perez-Garcia, M., Maya-Lastra, C.A., Montero-Castro, J.C., Godden, G.T., Cibrian-Jaramillo, A., Fisher, A.E., and Porter, J.M. (2021). Phylogenomics of Salvia L. subgenus Calosphace (Lamiaceae). Front. Plant Sci., 12.","DOI":"10.3389\/fpls.2021.725900"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/ajb2.1268","article-title":"Tracking temporal shifts in area, biomes, and pollinators in the radiation of Salvia (sages) across continents: Leveraging anchored hybrid enrichment and targeted sequence data","volume":"106","author":"Kriebel","year":"2019","journal-title":"Am. J. Bot."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1093\/bioinformatics\/bty633","article-title":"Ape 5.0: An environment for modern phylogenetics and evolutionary analyses in r","volume":"35","author":"Paradis","year":"2019","journal-title":"Bioinformatics"},{"key":"ref_17","unstructured":"R Core Team (2021). R: A Language and Environment for Statistical Computing, R foundation for Statistical Computing. Available online: https:\/\/www.R-project.org\/."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.2041-210X.2011.00169.x","article-title":"Phytools: An R package for phylogenetic comparative biology (and other things)","volume":"3","author":"Revell","year":"2012","journal-title":"Methods Ecol. Evol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"5967","DOI":"10.1021\/cr200058f","article-title":"Constituents from Salvia species and their biological activities","volume":"112","author":"Wu","year":"2012","journal-title":"Chem. Rev."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Eksi, G., Kurbanoglu, S., and Erdem, S.A. (2020). Analysis of diterpenes and diterpenoids. Recent Advances in Natural Products Analysis, Elsevier.","DOI":"10.1016\/B978-0-12-816455-6.00009-3"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1016\/0031-9422(88)80685-X","article-title":"Clerodane diterpenoids from Salvia melissodora","volume":"27","author":"Esquivel","year":"1988","journal-title":"Phytochemistry"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/0031-9422(89)80051-2","article-title":"Further ent-clerodane diterpenoids from Salvia melissodora","volume":"28","author":"Esquivel","year":"1989","journal-title":"Phytochemistry"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"11593","DOI":"10.1016\/S0040-4020(01)85654-4","article-title":"Salvigenane and isosalvipuberulan diterpenoids from Salvia leucantha","volume":"50","author":"Esquivel","year":"1994","journal-title":"Tetrahedron"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/cbdv.200590051","article-title":"Abietane diterpenoids from the roots of some mexican Salvia species (Labiatae): Chemical diversity, phytogeographical significance, and cytotoxic activity","volume":"2","author":"Esquivel","year":"2005","journal-title":"Chem. Biodivers."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0031-9422(00)97023-7","article-title":"Tilifolidione, a cycloheptanenapthoquinone-type diterpenoid of abietanic origin from the roots of Salvia tiliaefolia","volume":"36","author":"Luis","year":"1994","journal-title":"Phytochemistry"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/s11418-006-0037-3","article-title":"A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha Cav","volume":"60","author":"Narukawa","year":"2006","journal-title":"J. Nat. Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"4429","DOI":"10.1021\/ol801620u","article-title":"Salvileucalin B, A novel diterpenoid with an unprecedented rearranged neoclerodane skeleton from Salvia leucantha Cav","volume":"10","author":"Aoyagi","year":"2008","journal-title":"Org. Lett."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"5507","DOI":"10.1016\/j.tet.2016.07.037","article-title":"neo-Clerodanes from the aerial parts of Salvia leucantha","volume":"72","author":"Jiang","year":"2016","journal-title":"Tetrahedron"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.fitote.2017.09.013","article-title":"New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia","volume":"123","author":"Fan","year":"2017","journal-title":"Fitoterapia"},{"key":"ref_30","first-page":"1021","article-title":"Factors affecting biomass growth and production of essential oil from leaf and flower of Salvia leucantha Cav. Essent. Oil-Bear","volume":"21","author":"Inderaja","year":"2018","journal-title":"Plants"},{"key":"ref_31","first-page":"4610","article-title":"A new neo-clerodane diterpenoid from Salvia tiliifolia","volume":"51","author":"Fan","year":"2020","journal-title":"Chin. Tradit. Herb. Drugs"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.fitote.2018.03.007","article-title":"Neo-clerodane and abietane diterpenoids with neurotrophic activities from the aerial parts of Salvia leucantha Cav","volume":"127","author":"Li","year":"2018","journal-title":"Fitoterapia"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1039\/C5NP00137D","article-title":"Clerodane diterpenes: Sources, structures, and biological activities","volume":"33","author":"Li","year":"2016","journal-title":"Nat. Prod. Rep."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/S0040-4020(01)01232-7","article-title":"Biosynthesis of abietane diterpenoids in cultured cells of Torreya nucifera var. radicans: Biosynthetic inequality of the FPP part and the terminal IPP","volume":"58","author":"Yang","year":"2002","journal-title":"Tetrahedron"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1007\/s10886-006-9191-z","article-title":"Rapid analysis of abietanes in conifers","volume":"32","author":"Kersten","year":"2006","journal-title":"J. Chem. Ecol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"154133","DOI":"10.1016\/j.tetlet.2022.154133","article-title":"Recent advances in abietane\/icetexane synthesis","volume":"108","author":"Kang","year":"2022","journal-title":"Tetrahedron Lett."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"4067","DOI":"10.1016\/0031-9422(91)83468-Z","article-title":"Diterpenes from Salvia mellifera","volume":"30","author":"Brito","year":"1991","journal-title":"Phytochemistry"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/0031-9422(93)85463-2","article-title":"C-16 Hydroxylated abietane diterpenes from Salvia mellifera","volume":"33","author":"Luis","year":"1993","journal-title":"Phytochemistry"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/0031-9422(93)85376-3","article-title":"Abietane diterpenes from Salvia munzii","volume":"34","author":"Luis","year":"1993","journal-title":"Phytochemistry"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"4993","DOI":"10.1016\/S0040-4020(01)80415-4","article-title":"C-16 Hydroxylated abietane diterpenes from Salvia mellifera. Absolute configuration and biogenetic implications","volume":"49","author":"Luis","year":"1993","journal-title":"Tetrahedron"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0031-9422(06)80130-5","article-title":"Diterpenes from the aerial part of Salvia columbariae","volume":"35","author":"Luis","year":"1994","journal-title":"Phytochemistry"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S0031-9422(00)97049-3","article-title":"Columbaridione, a diterpenequinone from Salvia columbariae","volume":"36","author":"Luis","year":"1994","journal-title":"Phytochemistry"},{"key":"ref_43","first-page":"172","article-title":"Bioactive diterpenoids isolated from Salvia mellifera","volume":"10","author":"Moujir","year":"1996","journal-title":"Phytochem. Res."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1093\/ecam\/neh067","article-title":"Salvia columbariae contains tanshinones","volume":"2","author":"Adams","year":"2005","journal-title":"Evid. Based Complement. Altern. Med."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1021\/np060279i","article-title":"Abietane diterpenoids from Salvia pachyphylla and S. clevelandii with cytotoxic activity against human cancer cell lines","volume":"69","author":"Guerrero","year":"2006","journal-title":"J. Nat. Prod."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1080\/14786419.2016.1269096","article-title":"Phytochemical and biological evaluation of Salvia apiana","volume":"31","author":"Srivedavyasasri","year":"2017","journal-title":"Nat. Prod. Res."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1016\/S0040-4039(00)78129-9","article-title":"Isolation and structure of two diterpene quinones from Salvia ballotaeflora Benth. (Labiatae)","volume":"29","author":"Watson","year":"1976","journal-title":"Tetrahedron Lett."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0031-9422(88)80617-4","article-title":"Abietane diterpenoids from Salvia pubescens","volume":"27","author":"Galicia","year":"1988","journal-title":"Phytochemistry"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1016\/S0031-9422(00)97824-5","article-title":"Abietane diterpenoids of Salvia anastomosans","volume":"28","author":"Ramamoorthy","year":"1989","journal-title":"Phytochemistry"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0031-9422(97)00310-5","article-title":"Abietane and icetexane diterpenoids from Salvia ballotaeflora and Salvia axillaris","volume":"46","author":"Esquivel","year":"1997","journal-title":"Phytochemistry"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/ptr.1898","article-title":"The pharmacological effects of Salvia species on the central nervous system","volume":"20","author":"Imanshahidi","year":"2006","journal-title":"Phytother. Res."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.tifs.2018.08.008","article-title":"Salvia spp. plants: From farm to food applications and phytopharmacotherapy","volume":"80","author":"Ozcelik","year":"2018","journal-title":"Trends Food Sci. Technol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1055\/a-1087-8276","article-title":"Current state of the art on the antioxidant activity of Sage (Salvia spp.) and its bioactive components","volume":"86","author":"Poulios","year":"2020","journal-title":"Planta Med."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"15","DOI":"10.18596\/jotcsa.463681","article-title":"Determination of antimicrobial and biological activities of Salvia sclarea L. (Lamiaceae) Extracts","volume":"6","author":"Soyer","year":"2019","journal-title":"J. Turk. Chem. Soc. A Chem."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1055\/s-2006-961436","article-title":"A novel antimicrobial abietane-type diterpene from Salvia albocaerulea","volume":"58","year":"1992","journal-title":"Lett. Planta Med."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1016\/0031-9422(92)83130-Q","article-title":"Diterpenes and diterpene quinones from the roots of Salvia apiana","volume":"31","author":"Aguiar","year":"1992","journal-title":"Phytochemistry"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0031-9422(00)89808-8","article-title":"Diterpenoids from Salvia coulteri","volume":"36","author":"Frontana","year":"1994","journal-title":"Phytochemistry"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0031-9422(94)00854-M","article-title":"Abietane and icetexane diterpenoids from the roots of Salvia aspera","volume":"39","author":"Esquivel","year":"1995","journal-title":"Phytochemistry"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1080\/10575639708043720","article-title":"Abietane and icetexane diterpenoids from Salvia pubescens","volume":"10","author":"Esquivel","year":"1997","journal-title":"Nat. Prod. Lett."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0305-1978(89)90005-7","article-title":"A first study of antibacterial activity of diterpenes isolated from some Salvia species (Lamiaceae)","volume":"17","author":"Abad","year":"1989","journal-title":"Biochem. Syst. Ecol."},{"key":"ref_61","unstructured":"Ruiz, A.C. (2017). Estudio fitoqu\u00edmico de Salvia pannosa Fernald. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1055\/s-0028-1097724","article-title":"Three new diterpene quinones from Salvia ballotaeflora","volume":"30","author":"Watson","year":"1976","journal-title":"Planta Med."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"3297","DOI":"10.1016\/S0031-9422(00)82491-7","article-title":"Diterpenoid abietane quinones isolated from Salvia regla","volume":"26","author":"Esquivel","year":"1987","journal-title":"Phytochemistry"},{"key":"ref_64","unstructured":"Gavi\u00f1o, R. (1994). Estudio fitoqu\u00edmico de Salvia recurva. [Master\u2019s Thesis, UNAM]."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0031-9422(00)90438-2","article-title":"Abietane and neo-clerodane diterpenoids from Salvia lavanduloides","volume":"37","author":"Maldonado","year":"1994","journal-title":"Phytochemistry"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1076\/phbi.36.2.77.4611","article-title":"Antimicrobial diterpenes from Salvia reptans","volume":"36","author":"Miranda","year":"1998","journal-title":"Pharm. Biol."},{"key":"ref_67","first-page":"1934578X19862650","article-title":"Configurational study of diastereoisomeric royleanone diterpenoids from Salvia concolor","volume":"14","author":"Salazar","year":"2019","journal-title":"Nat. Prod. Commun."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1080\/14786410512331328731","article-title":"Rearranged icetexane diterpenoids from the roots of Salvia thymoides (Labiatae)","volume":"19","author":"Esquivel","year":"2005","journal-title":"Nat. Prod. Res."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/0031-9422(92)80282-J","article-title":"Diterpenes from Salvia mellifera and their biogenetic significance","volume":"31","author":"Aguiar","year":"1992","journal-title":"Phytochemistry"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0031-9422(97)00492-5","article-title":"Abietane diterpenoids from Salvia chionopeplica","volume":"47","author":"Luis","year":"1998","journal-title":"Phytochemistry"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/10412905.2010.9700314","article-title":"Volatile constituents of the aerial parts of Salvia apiana Jepson","volume":"22","author":"Takeoka","year":"2010","journal-title":"J. Essent. Oil Res."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"13","DOI":"10.2174\/1874848101205010013","article-title":"\u03b2-Sitosterol Lithospermate from Salvia columbariae","volume":"5","author":"Adams","year":"2012","journal-title":"J. Nat. Prod."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1021\/acs.jnatprod.6b01053","article-title":"Antibacterial and hypoglycemic diterpenoids from Salvia chamaedryoides","volume":"80","author":"Bisio","year":"2017","journal-title":"J. Nat. Prod."},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Almada-Taylor, G., D\u00edaz-Rubio, L., Salazar-Aranda, R., Waksman de Torres, N., Uranga-Solis, C., Delgadillo-Rodr\u00edguez, J., Ramos, M.A., Padr\u00f3n, J.M., Hern\u00e1ndez-Mart\u00ednez, R., and C\u00f3rdova-Guerrero, I. (2018). Biological activities of extracts from aerial parts of Salvia pachyphylla Epling ex Munz. Plants, 7.","DOI":"10.20944\/preprints201810.0408.v1"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1039\/D1FO02988F","article-title":"Insights into the neuroprotective effects of Salvia officinalis L. and Salvia microphylla Kunth in the memory impairment rat model","volume":"13","author":"Ayoub","year":"2022","journal-title":"Food Funct."},{"key":"ref_76","unstructured":"S\u00e1nchez, V.M.C. (1983). Estudio fitoquimico de mortonia diffusa. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0031-9422(94)00569-F","article-title":"Abietane and icetexane diterpenoids from Salvia candicans","volume":"38","year":"1995","journal-title":"Phytochemistry"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"8895","DOI":"10.3390\/molecules18088895","article-title":"Antidiarrheal activity of 19-deoxyicetexone isolated from Salvia ballotiflora benth in mice and rats","volume":"18","year":"2013","journal-title":"Molecules"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1021\/acs.jnatprod.8b00952","article-title":"Structure and absolute configuration of abietane diterpenoids from Salvia clinopodioides: Antioxidant, antiprotozoal, and antipropulsive activities","volume":"82","author":"Calzada","year":"2019","journal-title":"J. Nat. Prod."},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Bustos-Brito, C., Torres-Medicis, J.P., Bedolla-Garc\u00eda, B.Y., Zamudio, S., Ram\u00edrez-Apan, T., Mac\u00edas-Rubalcava, M.L., Quijano, L., and Esquivel, B. (2024). Structure, Absolute configuration, antiproliferative and phytotoxic activities of icetexane and abietane diterpenoids from Salvia carranzae and chemotaxonomic implications. Molecules, 9.","DOI":"10.3390\/molecules29061226"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1016\/0031-9422(90)80149-B","article-title":"Terpenoids from Salvia mellifera","volume":"29","author":"Ravelo","year":"1990","journal-title":"Phytochemistry"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1021\/np050041e","article-title":"Unsaturated diterpenoids with a novel carbocyclic skeleton from Salvia xalapensis","volume":"68","author":"Esquivel","year":"2005","journal-title":"J. Nat. Prod."},{"key":"ref_83","doi-asserted-by":"crossref","unstructured":"Ortiz-Mendoza, N., San Miguel-Ch\u00e1vez, R., Mart\u00ednez-Gordillo, M.J., Basurto-Pe\u00f1a, F.A., Palma-Tenango, M., and Aguirre-Hern\u00e1ndez, E. (2023). Variation in terpenoid and flavonoid content in different samples of Salvia semiatrata collected from Oaxaca, Mexico, and its effects on antinociceptive activity. Metabolites, 13.","DOI":"10.3390\/metabo13070866"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/0031-9422(88)80442-4","article-title":"Quinone methide diterpenoids from the roots of Salvia texana","volume":"27","author":"Aguiar","year":"1988","journal-title":"Phytochemistry"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.1016\/0040-4039(96)00799-X","article-title":"Apiananes: C23 terpenoids with a new type of skeleton from Salvia apiana","volume":"37","author":"Luis","year":"1996","journal-title":"Tetrahedron Lett."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1039\/np9920900243","article-title":"Clerodane diterpenoids","volume":"9","author":"Merritt","year":"1992","journal-title":"Nat. Prod. Rep."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1021\/np030313i","article-title":"Divinatorins A-C, new neoclerodane diterpenoids from the controlled sage Salvia divinorum","volume":"66","author":"Bigham","year":"2003","journal-title":"J. Nat. Prod."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"104672","DOI":"10.1016\/j.fitote.2020.104672","article-title":"Rearranged neoclerodane diterpenoids from the aerial parts of Salvia hispanica L.","volume":"146","author":"Fan","year":"2020","journal-title":"Fitoterapia"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.tetlet.2017.12.010","article-title":"Salvihispin A and its glycoside, two neo-clerodane diterpenoids with neurotrophic activities from Salvia hispanica L.","volume":"59","author":"Fan","year":"2018","journal-title":"Tetrahedron Lett."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"112065","DOI":"10.1016\/j.phytochem.2019.112065","article-title":"Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects","volume":"166","author":"Fan","year":"2019","journal-title":"Phytochemistry"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1002\/hlca.200490088","article-title":"Novel diterpenoids from Salvia dugesii","volume":"87","author":"Xu","year":"2004","journal-title":"Helv. Chim. Acta"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1248\/cpb.54.1338","article-title":"Polystachyne F, a 5,10-seco-Neoclerodane from Salvia polystachia","volume":"54","author":"Ortega","year":"2006","journal-title":"Chem. Pharm. Bull."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.phytol.2015.10.005","article-title":"Antibacterial activity of constituents from Salvia buchananii Hedge (Lamiaceae)","volume":"14","author":"Bisio","year":"2015","journal-title":"Phytochem. Lett."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s13659-011-0016-6","article-title":"neo-Clerodane diterpenoids from Salvia dugesii and their bioactive studies","volume":"1","author":"Xu","year":"2011","journal-title":"Nat. Prod. Bioprospect."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1021\/np3001464","article-title":"Neo-clerodane diterpenes from Salvia herbacea","volume":"75","author":"Bautista","year":"2012","journal-title":"J. Nat. Prod."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1021\/acs.jnatprod.7b00591","article-title":"Neo-Clerodane diterpenoids from Salvia polystachya stimulate the expression of extracellular matrix components in human dermal fibroblasts","volume":"80","author":"Bautista","year":"2017","journal-title":"J. Nat. Prod."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1021\/np400606g","article-title":"Hydroxyclerodanes from Salvia shannoni","volume":"76","author":"Bautista","year":"2013","journal-title":"J. Nat. Prod."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s43450-020-00077-7","article-title":"Antiprotozoal activity of secondary metabolites from Salvia circinata","volume":"30","author":"Calzada","year":"2020","journal-title":"Rev. Bras. Farmacogn."},{"key":"ref_99","doi-asserted-by":"crossref","unstructured":"Salinas-Arellano, E., P\u00e9rez-V\u00e1squez, A., Rivero-Cruz, I., Torres-Colin, R., Gonz\u00e1lez-Andrade, M., Rangel-Grimaldo, M., and Mata, R. (2020). Flavonoids and terpenoids with PTP-1B inhibitory properties from the infusion of Salvia amarissima ortega. Molecules, 25.","DOI":"10.3390\/molecules25153530"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0031-9422(99)00466-5","article-title":"Polystachynes A-E, cis-neo-clerodane diterpenoids from Salvia polystachya","volume":"53","author":"Maldonado","year":"2000","journal-title":"Phytochemistry"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"130367","DOI":"10.1016\/j.molstruc.2021.130367","article-title":"Clerodane and 5 10-seco-clerodane-type diterpenoids from Salvia involucrata","volume":"1237","author":"Zamudio","year":"2021","journal-title":"J. Mol. Struct."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1021\/acs.jnatprod.6b00605","article-title":"neo-clerodane diterpenoids and other constituents of Salvia filipes","volume":"79","author":"Maldonado","year":"2016","journal-title":"J. Nat. Prod."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1021\/acs.jnatprod.0c00313","article-title":"Hydroxy- neo-Clerodanes and 5,10-seco-neo-Clerodanes from Salvia decora","volume":"83","year":"2020","journal-title":"J. Nat. Prod."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.molstruc.2017.03.091","article-title":"NMR analysis and crystal structure of hydroxyclerodanes from Mexican Salvia species","volume":"1141","author":"Ortega","year":"2017","journal-title":"J. Mol. Struct."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1016\/j.phytochem.2004.08.012","article-title":"Diterpenoid glucosides from Salvia greggii","volume":"65","author":"Kawahara","year":"2004","journal-title":"Phytochemistry"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1177\/1040638721995784","article-title":"Clinical, pathologic, and toxicologic characterization of Salvia reflexa (lance-leaf sage) poisoning in cattle fed contaminated hay","volume":"33","author":"Panter","year":"2021","journal-title":"J. Vet. Diagn. Investig."},{"key":"ref_107","unstructured":"Guzm\u00e1n, F.G. (1997). Estudio fitoqu\u00edmico de Salvia carnea. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1139\/v87-445","article-title":"Structure of kerlinic acid from Salvia keerlii. Chemical correlation with melisodoric acid","volume":"65","author":"Garcia","year":"1987","journal-title":"Can. J. Chem."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0031-9422(00)81437-5","article-title":"Lasianthin, a neo-clerodane diterpenoid from Salvia lasiantha","volume":"26","author":"Esquivel","year":"1987","journal-title":"Phytochemistry"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s11418-005-0007-1","article-title":"Four new diterpenoids from Salvia fulgens Cav","volume":"60","author":"Narukawa","year":"2006","journal-title":"J. Nat. Med."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1016\/S0031-9422(00)81749-5","article-title":"Diterpenes from Salvia breviflora","volume":"26","author":"Cuevas","year":"1987","journal-title":"Phytochemistry"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1021\/np50052a029","article-title":"The diterpenoid constituents of Salvia fulgens and Salvia microphylla","volume":"50","author":"Esquivel","year":"1987","journal-title":"J. Nat. Prod."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/0031-9422(95)00083-J","article-title":"Abietane and clerodane diterpenes from Salvia regla","volume":"39","author":"Ortega","year":"1995","journal-title":"Phytochemistry"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1016\/S0031-9422(00)82548-0","article-title":"Neo-clerodane-type diterpenoids from Salvia keerlii","volume":"24","author":"Esquivel","year":"1985","journal-title":"Phytochemistry"},{"key":"ref_115","unstructured":"L\u00f3pez, C.M.E. (2020). Aislamiento y determinaci\u00f3n estructural de los metabolitos secundarios presentes en las hojas de Salvia longispicata. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"134490","DOI":"10.1016\/j.tet.2025.134490","article-title":"Phytotoxic neo-clerodane and rearranged neo-clerodane type diterpenoids from Salvia albiflora","volume":"174","author":"Zamudio","year":"2025","journal-title":"Tetrahedron"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"e2100517","DOI":"10.1002\/cbdv.202100517","article-title":"Neo-clerodane diterpenoids with hypoglycemic effects in vivo from the aerial parts of Salvia hispanica L.","volume":"18","author":"Fan","year":"2021","journal-title":"Chem. Biodivers."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/S0031-9422(97)00168-4","article-title":"Languidulane, clerodane and secoclerodane diterpenes from Salvia tonalensis","volume":"45","author":"Maldonado","year":"1997","journal-title":"Phytochemistry"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/S0031-9422(00)90671-X","article-title":"7-epi-rhyacophiline, a 5,6-secoclerodane diterpene from Salvia rhyacophila","volume":"35","author":"Ortega","year":"1993","journal-title":"Phytochemistry"},{"key":"ref_120","unstructured":"Guerrero, R.D. (2021). Aislamiento y elucidaci\u00f3n estructural de los componentes terp\u00e9nicos presentes en Salvia ballotiflora y Salvia gesneriflora. [Masther\u2019s Thesis, UNAM]."},{"key":"ref_121","first-page":"1002","article-title":"A new neo-clerodane diterpenoid from Salvia farinacea Benth","volume":"59","author":"Li","year":"2024","journal-title":"Yaoxue Xuebao"},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF01673679","article-title":"Tonalensin, a 5,10-seco-neoclerodane diterpenoid","volume":"26","author":"Toscano","year":"1996","journal-title":"J. Chem. Crystallogr."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.3987\/COM-20-14342","article-title":"Five new highly oxidized neoclerodane diterpenes, salvileucalin E-I from Salvia leucantha","volume":"100","author":"Aoyagi","year":"2020","journal-title":"Heterocycles"},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1016\/0031-9422(91)83644-Z","article-title":"Clerodane and seco-clerodane diterpenoids from Salvia reptans","volume":"34","author":"Esquivel","year":"1991","journal-title":"Phytochemistry"},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/ddr.21432","article-title":"Anti-inflammatory and antinociceptive effects of tilifodiolide, isolated from Salvia tiliifolia Vahl (Lamiaceae)","volume":"79","year":"2018","journal-title":"Drug Dev. Res."},{"key":"ref_126","unstructured":"Paleo, G.E. (2004). Estudio fitoqu\u00edmico de Salvia longispicata. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"9109","DOI":"10.3390\/molecules16119109","article-title":"Structure of salvioccidentalin, a diterpenoid with a rearranged neo-clerodane skeleton from Salvia occidentalis","volume":"16","year":"2011","journal-title":"Molecules"},{"key":"ref_128","unstructured":"Aguilera, A.L. (1994). Phytochemistry Contribution of Salvia mexicana. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_129","unstructured":"Dom\u00ednguez, R.M. (1995). Aislamiento y elucidaci\u00f3n estructural de los componentes diterpenicas de Salvia leucantha, Cav. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/S0031-9422(99)00324-6","article-title":"Clerodane diterpenoids from Salvia blepharophylla","volume":"58","author":"Bisio","year":"1999","journal-title":"Phytochemistry"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.phytochem.2010.11.011","article-title":"Phytotoxic clerodane diterpenes from Salvia miniata Fernald (Lamiaceae)","volume":"72","author":"Bisio","year":"2011","journal-title":"Phytochemistry"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S0031-9422(00)94798-8","article-title":"Antiviral diterpenes from Salvia officinalis","volume":"35","author":"Tada","year":"1994","journal-title":"Phytochemistry"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1016\/j.phymed.2016.09.008","article-title":"Sageone, a diterpene from Rosmarinus officinalis, synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells","volume":"23","author":"Shrestha","year":"2016","journal-title":"Phytomedicine"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/0031-9422(90)80066-P","article-title":"16-hydroxycarnosic acid, a diterpene from Salvia apiana","volume":"29","author":"Dentali","year":"1990","journal-title":"Phytochemistry"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"115308","DOI":"10.1016\/j.jpba.2023.115308","article-title":"Effect directed analysis of bioactive compounds in leaf extracts from two Salvia species by High-performance thin-layer chromatography","volume":"227","author":"Wong","year":"2023","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"4735","DOI":"10.2147\/DDDT.S266911","article-title":"Pharmacological activity and mechanism of tanshinone IIA in related diseases","volume":"14","author":"Guo","year":"2020","journal-title":"Drug Des. Devel Ther."},{"key":"ref_137","doi-asserted-by":"crossref","unstructured":"Ding, Z., Deng, Y., Luo, H., Liu, C., Yang, M., Xue, H., and Chen, Z. (2025). Progress of tanshinone IIA against respiratory diseases: Therapeutic targets and potential mechanisms. Front. Pharmacol., 16.","DOI":"10.3389\/fphar.2025.1505672"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1515\/znc-2006-3-404","article-title":"Cytotoxic abietane diterpenes from Hyptis martiusii Benth","volume":"61","author":"Lima","year":"2006","journal-title":"Z. Naturforschung C J. Biosci."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"4876","DOI":"10.1016\/j.bmc.2011.06.067","article-title":"In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica","volume":"19","author":"Fronza","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s00210-020-01967-2","article-title":"4,5-Seco-5,10-friedo-abietane-type diterpenoids with anticancer activity from Salvia atropatana Bunge","volume":"394","author":"Shakeri","year":"2021","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"ref_141","doi-asserted-by":"crossref","unstructured":"Habtemariam, S. (2023). Anti-Inflammatory therapeutic mechanisms of natural products: Insight from rosemary diterpenes, carnosic acid and carnosol. Biomedicines, 11.","DOI":"10.3390\/biomedicines11020545"},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"7627","DOI":"10.1021\/acs.jpcb.4c02949","article-title":"Antioxidation activity enhancement by intramolecular hydrogen bond and non-browning mechanism of active ingredients in rosemary: Carnosic acid and carnosol","volume":"128","author":"Liu","year":"2024","journal-title":"J. Phys. Chem. B"},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"3763","DOI":"10.1002\/ptr.8213","article-title":"Carnosol prevents cardiac remodeling and ventricular arrhythmias in pressure overload-induced heart failure mice","volume":"38","author":"Fang","year":"2024","journal-title":"Phytother. Res."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/cbin.12258","article-title":"Carnosol alleviates cisplatin-induced acute kidney injury by regulating apoptosis and pyroptosis","volume":"49","author":"Li","year":"2025","journal-title":"Cell Biol. Int."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"5234","DOI":"10.1016\/j.bmcl.2014.09.061","article-title":"Antimalarial activity of abietane ferruginol analogues possessing a phthalimide group","volume":"24","author":"Clark","year":"2014","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00436-014-4211-3","article-title":"Abietane diterpenoids from Salvia sclarea transformed roots as growth inhibitors of pathogenic Acanthamoeba spp.","volume":"114","author":"Derda","year":"2015","journal-title":"Parasitol. Res."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3233\/JAD-170701","article-title":"Neuroprotective effects of ferruginol, jatrophone, and junicedric acid against amyloid-\u03b2 injury in hippocampal neurons","volume":"63","author":"Zolezzi","year":"2018","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1055\/s-2003-39705","article-title":"Studies on di- and triterpenoids from Salvia staminea with cytotoxic activity","volume":"69","author":"Topcu","year":"2003","journal-title":"Planta Med."},{"key":"ref_149","first-page":"131","article-title":"Antimicrobial and antileishmanial activities of diterpenoids isolated from the roots of Salvia deserta","volume":"82","author":"Cantrell","year":"2016","journal-title":"Planta Med."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1080\/14786419.2021.1952202","article-title":"Cytotoxic abietane-type diterpenoids from roots of Salvia spinosa and their in Silico pharmacophore modeling","volume":"36","author":"Jassbi","year":"2022","journal-title":"Nat. Prod. Res."},{"key":"ref_151","first-page":"37","article-title":"Chemical diversity of the biological active ingredients of Salvia officinalis and some closely related species","volume":"77","author":"Hohmann","year":"2007","journal-title":"Acta Pharm. Hung."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1055\/s-2006-960887","article-title":"Cytstatic and antibacterial activity of some compounds isolated from several Lamiaceae species from the Canary Islands","volume":"56","author":"Darias","year":"1990","journal-title":"Planta Med."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1021\/jf011314o","article-title":"Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method","volume":"50","author":"Miura","year":"2002","journal-title":"J. Agric. Food Chem."},{"key":"ref_154","doi-asserted-by":"crossref","unstructured":"Bakhsh, T., Abuzahrah, S.S., Qahl, S.H., Akela, M.A., and Rather, I.A. (2023). Sugiol masters apoptotic precision to halt gastric cancer cell proliferation. Pharmaceuticals, 16.","DOI":"10.3390\/ph16111528"},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"ovae077","DOI":"10.1093\/lambio\/ovae077","article-title":"Isolation and identification of antimicrobial multicyclic terpenoids from the medicinal plant Salvia officinalis and development of a formulation against clinical Staphylococcus aureus strains","volume":"77","author":"Purgato","year":"2024","journal-title":"Lett. Appl. Microbiol."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.phytochem.2013.09.011","article-title":"Cancer chemopreventive diterpenes from Salvia corrugata","volume":"96","author":"Giacomelli","year":"2013","journal-title":"Phytochemistry"},{"key":"ref_157","doi-asserted-by":"crossref","unstructured":"Campos-Xolalpa, N., Alonso-Castro, \u00c1.J., Ort\u00edz-Sanchez, E., Zapata-Morales, J.R., Gonz\u00e1lez-Ch\u00e1vez, M.M., and P\u00e9rez, S. (2021). Anti-inflammatory and antitumor activities of the chloroform extract and anti-inflammatory effect of the three diterpenes isolated from Salvia ballotiflora Benth. BMC Complement. Med. Ther., 21.","DOI":"10.1186\/s12906-020-03179-w"},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"682","DOI":"10.2174\/1874467215666221005115007","article-title":"Immunomodulatory activity of diterpenes over innate immunity and cytokine production in a human alveolar epithelial cell line infected with mycobacterium tuberculosis","volume":"16","author":"SNM","year":"2023","journal-title":"Curr. Mol. Pharmacol."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1055\/s-0031-1280454","article-title":"Diterpenoids including a novel dimeric conjugate from Salvia leriaefolia","volume":"78","author":"Choudhary","year":"2012","journal-title":"Planta Med."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.jep.2018.02.012","article-title":"Sessein and isosessein with anti-inflammatory, antibacterial and antioxidant activity isolated from Salvia sessei Benth","volume":"217","author":"Zamilpa","year":"2018","journal-title":"J. Ethnopharmacol."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fitote.2016.08.007","article-title":"Structural elucidation and evaluation of multidrug-resistance modulatory capability of amarissinins A\u2013C, diterpenes derived from Salvia amarissima","volume":"114","author":"Bautista","year":"2016","journal-title":"Fitoterapia"},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"114996","DOI":"10.1016\/j.jep.2022.114996","article-title":"Anti-arthritic and anti-inflammatory effects of Baccharis conferta Kunth in a kaolin\/carrageenan-induced monoarthritis model","volume":"288","author":"Zamilpa","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"ref_163","doi-asserted-by":"crossref","unstructured":"Guti\u00e9rrez-Rom\u00e1n, A.S., Trejo-Tapia, G., Herrera-Ru\u00edz, M., Nayeli, M.B., Trejo-Espino, J.L., Zamilpa, A., and Manas\u00e9s, G.C. (2020). Effect of terpenoids and flavonoids isolated from Baccharis conferta Kunth on TPA-Induced ear edema in mice. Molecules, 25.","DOI":"10.3390\/molecules25061379"},{"key":"ref_164","doi-asserted-by":"crossref","unstructured":"Chen, J., Wu, X., and Yu, R. (2023). Unraveling the therapeutic mechanism of saussurea involucrata against rheumatoid arthritis: A network pharmacology and molecular modeling-based investigation. Nutrients, 15.","DOI":"10.3390\/nu15194294"},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1021\/acs.jnatprod.7b00155","article-title":"\u03b1-Glucosidase inhibitors from Salvia circinata","volume":"80","author":"Bye","year":"2017","journal-title":"J. Nat. Prod."},{"key":"ref_166","doi-asserted-by":"crossref","unstructured":"Moreno-P\u00e9rez, G.F., Gonz\u00e1lez-Trujano, M.E., Hernandez-Leon, A., Valle-Dorado, M.G., Vald\u00e9s-Cruz, A., Alvarado-V\u00e1squez, N., Aguirre-Hern\u00e1ndez, E., Salgado-Ceballos, H., and Pellicer, F. (2022). Antihyperalgesic and antiallodynic effects of amarisolide A and Salvia amarissima ortega in experimental fibromyalgia-type pain. Metabolites, 13.","DOI":"10.3390\/metabo13010059"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"355","DOI":"10.17129\/botsci.2187","article-title":"Amarisolide A and pedalitin as bioactive compounds in the antinociceptive effects of Salvia circinata (Lamiaceae)","volume":"97","year":"2019","journal-title":"Bot. Sci."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"113550","DOI":"10.1016\/j.jep.2020.113550","article-title":"Neo-clerodane diterpenic influence in the antinociceptive and anti-inflammatory properties of Salvia circinnata Cav","volume":"268","author":"Alberto","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"116352","DOI":"10.1016\/j.biopha.2024.116352","article-title":"Electroencephalographic profile of Salvia amarissima Ortega and amarisolide A in the absence and presence of PTZ-induced seizures in mice","volume":"173","year":"2024","journal-title":"BioMed Pharmacother."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/(SICI)1096-9063(199605)47:1<17::AID-PS378>3.0.CO;2-I","article-title":"Effect of clerodane-type diterpenoids isolated from Salvia spp. on the feeding behaviour of Spodoptera littoralis","volume":"47","author":"Simmonds","year":"1996","journal-title":"Pestic. Sci."},{"key":"ref_171","first-page":"1797","article-title":"Antimicrobial activity of neo-clerodane diterpenoids isolated from Lamiaceae species against pathogenic and food spoilage microorganisms","volume":"10","author":"Bozov","year":"2015","journal-title":"Nat. Prod. Commun."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1002\/ptr.2938","article-title":"Evaluation of the antiprotozoal activity of neo-clerodane type diterpenes from Salvia polystachya against Entamoeba histolytica and Giardia lamblia","volume":"24","author":"Calzada","year":"2010","journal-title":"Phytother. Res."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1002\/ptr.5421","article-title":"Antiamoebic and antigiardial activity of clerodane diterpenes from Mexican Salvia species used for the treatment of diarrhea","volume":"29","author":"Calzada","year":"2015","journal-title":"Phytother. Res."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"3671","DOI":"10.1021\/acs.jnatprod.0c00892","article-title":"Linearolactone and kaempferol disrupt the actin cytoskeleton in Entamoeba histolytica: Inhibition of amoebic liver abscess development","volume":"83","author":"Calzada","year":"2020","journal-title":"J. Nat. Prod."},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Arg\u00fcello-Garc\u00eda, R., Calzada, F., Ch\u00e1vez-Mungu\u00eda, B., Matus-Meza, A.S., Bautista, E., Barbosa, E., Velazquez, C., Hern\u00e1ndez-Caballero, M.E., Ordo\u00f1ez-Razo, R.M., and Vel\u00e1zquez-Dom\u00ednguez, J.A. (2022). Linearolactone induces necrotic-like death in giardia intestinalis trophozoites: Prediction of a likely target. Pharmaceuticals, 15.","DOI":"10.3390\/ph15070809"},{"key":"ref_176","doi-asserted-by":"crossref","unstructured":"Varela-Rodr\u00edguez, L., Calzada, F., Vel\u00e1zquez-Dom\u00ednguez, J.A., Hern\u00e1ndez-Ram\u00edrez, V.I., Varela-Rodr\u00edguez, H., Bautista, E., Herrera-Mart\u00ednez, M., Pichardo-Hern\u00e1ndez, D.L., Castellanos-Mijangos, R.D., and Ch\u00e1vez-Mungu\u00eda, B. (2024). Toxicological evaluation of kaempferol and linearolactone as treatments for amoebic liver abscess development in Mesocricetus auratus. Int. J. Mol. Sci., 25.","DOI":"10.20944\/preprints202407.0797.v1"},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1002\/ddr.21578","article-title":"Antidiarrheal, vasorelaxant, and neuropharmacological actions of the diterpene tilifodiolide","volume":"80","year":"2019","journal-title":"Drug Dev. Res."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1080\/13880209.2020.1784235","article-title":"Antinociceptive and anxiolytic-like effects of a neo-clerodane diterpene from Salvia semiatrata aerial parts","volume":"58","year":"2020","journal-title":"Pharm. Biol."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"e1219","DOI":"10.1097\/CCM.0000000000001959","article-title":"The role of \u03ba opioid receptor in brain ischemia","volume":"44","author":"Chen","year":"2016","journal-title":"Crit. Care Med."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/ejp.1002","article-title":"The analgesic and anti-inflammatory effects of Salvinorin A analogue \u03b2-tetrahydropyran Salvinorin B in mice","volume":"21","author":"Paton","year":"2017","journal-title":"Eur. J. Pain"},{"key":"ref_181","doi-asserted-by":"crossref","unstructured":"van de Wetering, R., Ewald, A., Welsh, S., Kornberger, L., Williamson, S.E., McElroy, B.D., Butelman, E.R., Prisinzano, T.E., and Kivell, B.M. (2023). The kappa opioid receptor agonist 16-bromo salvinorin a has anti-cocaine effects without significant effects on locomotion, food reward, learning and memory, or anxiety and depressive-like behaviors. Molecules, 28.","DOI":"10.3390\/molecules28124848"},{"key":"ref_182","first-page":"1163","article-title":"Diterpenes and antioxidative protection in drought-stressed Salvia officinalis plants","volume":"161","author":"Mueller","year":"2004","journal-title":"J. Plant Physiol."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/pm.pm_223_19","article-title":"Anti-inflammatory and antinociceptive activities of Salvia keerlii","volume":"16","year":"2020","journal-title":"Pharmacogn. Mag."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"456","DOI":"10.3109\/13880209.2010.523427","article-title":"Chemical composition and mosquito larvicidal activities of Salvia essential oils","volume":"49","author":"Mathew","year":"2011","journal-title":"Pharm. Biol."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1080\/14786410500462843","article-title":"Constituents of Salvia microphylla","volume":"20","year":"2006","journal-title":"Nat. Prod. Res."},{"key":"ref_186","unstructured":"Hern\u00e1ndez, H.P.A. (2005). Estudio qu\u00edmico biodirigido de las ra\u00edces de Salvia candicans. [Master\u2019s Thesis, UNAM]."},{"key":"ref_187","unstructured":"Gonz\u00e1lez, G.B. (1995). Estudio fitoqu\u00edmico de Salvia oaxacana Fern. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/0031-9422(89)80052-4","article-title":"Abietane type diterpenoids from Salvia fruticulosa. A revision of the structure of fruticulin B","volume":"28","author":"Esquivel","year":"1989","journal-title":"Phytochemistry"},{"key":"ref_189","unstructured":"Moreno, J.L.E. (2019). Aislamiento, determinaci\u00f3n estructural y evaluaci\u00f3n de la actividad biol\u00f3gica de metabolitos secundarios provenientes de Salvia axilliaris. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.1002\/jcb.27701","article-title":"Protein translation associated to PERK arm is a new target for regulation of metainflammation: A connection with hepatocyte cholesterol","volume":"120","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"ref_191","first-page":"421","article-title":"Diterpenoid quinones from Salvia species","volume":"19","author":"Huang","year":"1981","journal-title":"Acta Phytotax. Sin."},{"key":"ref_192","doi-asserted-by":"crossref","unstructured":"Afonso, A.F., Pereira, O.R., Fernandes, \u00c2.S.F., Calhelha, R.C., Silva, A.M.S., Ferreira, I.C.F.R., and Cardoso, S.M. (2019). The health-benefits and phytochemical profile of Salvia apiana and Salvia farinacea var. Victoria Blue decoctions. Antioxidants, 8.","DOI":"10.3390\/antiox8080241"},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"12309","DOI":"10.1016\/0040-4020(96)00717-X","article-title":"Hassananes: C23 terpenoids with a new type of skeleton from Salvia apiana Jeps","volume":"52","author":"Luis","year":"1996","journal-title":"Tetrahedron"},{"key":"ref_194","first-page":"81","article-title":"Diterpenos tipo abietano aislados de Salvia microphylla y su actividad inhibitoria de acetilcolinesterasa","volume":"47","author":"Maldonado","year":"2019","journal-title":"Rev. Latinoam. Qu\u00edm."},{"key":"ref_195","unstructured":"S\u00e1nchez, V.M.C. (1987). Estudio quimiotaxon\u00f3mico de Salvia goldmanii y Salvia anastomosans. [Master\u2019s Thesis, UNAM]."},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/S0305-1978(03)00037-1","article-title":"Chemodiversity of exudate flavonoids in some members of the Lamiaceae","volume":"31","author":"Roitman","year":"2003","journal-title":"Biochem. Syst. Ecol."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1021\/np4009893","article-title":"5,10-seco-neo-Clerodanes and neo-Clerodanes from Salvia microphylla","volume":"77","author":"Bautista","year":"2014","journal-title":"J. Nat. Prod."},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1002\/pca.2800050606","article-title":"Structural elucidation of infuscatin, a diterpenoid from Salvia infuscata","volume":"5","author":"Ortega","year":"1994","journal-title":"Phytochem. Anal."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S0031-9422(97)00013-7","article-title":"Neo-clerodane and languidulane diterpenoids from Salvia sousae and S. karwinskii","volume":"45","author":"Esquivel","year":"1997","journal-title":"Phytochemistry"},{"key":"ref_200","unstructured":"Fernandez de la Rosa, M.C. (1990). Estudio fitoqu\u00edmico de Salvia rhyacophila. [Bachelor\u2019s Thesis, UNAM]."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1016\/0031-9422(82)85257-6","article-title":"Salviacoccin, a neo-clerodane diterpenoid from Salvia coccinea","volume":"21","author":"Savona","year":"1982","journal-title":"Phytochemistry"},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0031-9422(00)85504-1","article-title":"Diterpenoids from Salvia greggii","volume":"25","author":"Bruno","year":"1986","journal-title":"Phytochemistry"},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1016\/S0031-9422(00)81700-8","article-title":"Clerodane diterpenoids of Salvia lineata","volume":"25","author":"Esquivel","year":"1986","journal-title":"Phytochemistry"},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"o559","DOI":"10.1107\/S160053680600050X","article-title":"1,10-Dehydrosalviarin","volume":"62","author":"Mattia","year":"2006","journal-title":"Acta Crystallogr. Sect. E Struct. Rep. Online"},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1021\/np960515x","article-title":"8-Hydroxysalviarin and 7,8-didehydrorhyacophiline, two new diterpenes from Salvia reflexa","volume":"59","author":"Nieto","year":"1996","journal-title":"J. Nat. Prod."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"7199","DOI":"10.1016\/S0040-4020(01)89722-2","article-title":"Clerodane and aromatic seco-clerodane diterpenoids from Salvia rhyacophila","volume":"47","author":"Esquivel","year":"1991","journal-title":"Tetrahedron"},{"key":"ref_207","unstructured":"Torres Medicis, J.P. (2021). Aislamiento y elucidaci\u00f3n estructural de los metabolitos secundarios de Salvia gesneriiflora y S. guevarae. Implicaciones quimiotaxon\u00f3micas. [Master\u2019s Thesis, UNAM]."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.phytochem.2014.10.033","article-title":"Antibacterial compounds from Salvia adenophora Fernald (Lamiaceae)","volume":"110","author":"Bisio","year":"2015","journal-title":"Phytochemistry"},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0031-9422(00)94779-4","article-title":"Neo-clerodane diterpenoids from Salvia madrensis L.","volume":"35","author":"Alvarado","year":"1994","journal-title":"Phytochemistry"},{"key":"ref_210","first-page":"207","article-title":"Estudio fitoqu\u00edmico de Salvia uruapana","volume":"47","year":"2003","journal-title":"Rev. Soc. Qu\u00edm. M\u00e9x."},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/10575630290020046","article-title":"Tri-nordammarane triterpenoids and neoclerodane diterpenoids from Salvia aspera (Labiatae)","volume":"16","author":"Esquivel","year":"2002","journal-title":"Nat. Prod. Lett."},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0031-9422(94)00531-W","article-title":"Clerodane diterpenoids from Salvia urolepis","volume":"38","author":"Esquivel","year":"1995","journal-title":"Phytochemistry"},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/S0031-9422(00)80356-8","article-title":"Salvifarin, X-ray structure determination of a cis neo-clerodane diterpenoid from Salvia farinacea","volume":"23","author":"Eguren","year":"1984","journal-title":"Phytochemistry"},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"139132","DOI":"10.1016\/j.molstruc.2024.139132","article-title":"Amarissinin F and its 16-epimer, two neo-clerodane diterpenoids from Salvia amarissima containing a 5-hydroxy-furan-2(5H)-one with MDR modulatory activity in cancer cells","volume":"1317","author":"Toscano","year":"2024","journal-title":"J. Mol. Struct."},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"154491","DOI":"10.1016\/j.tetlet.2023.154491","article-title":"neo-Clerodane and tiliifolane-type diterpenoids, and other constituents from Salvia pennellii","volume":"122","author":"Toscano","year":"2023","journal-title":"Tetrahedron Lett."},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0031-9422(91)83039-N","article-title":"Salvianduline C, a 5,6-secoclerodane diterpenoid from Salvia lavanduloides","volume":"31","author":"Maldonado","year":"1992","journal-title":"Phytochemistry"},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"3357","DOI":"10.1016\/0031-9422(91)83209-4","article-title":"Salviandulines A and B, two secoclerodane diterpenoids from Salvia lavanduloides","volume":"30","author":"Ortega","year":"1991","journal-title":"Phytochemistry"},{"key":"ref_218","first-page":"162","article-title":"Chemical constituents of Salvia urica and their antihyperglycemic and antipropulsive effects","volume":"102","author":"Valdes","year":"2024","journal-title":"Bot. Sci."},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0040-4039(00)92315-3","article-title":"Salvilanguidulines, four new diterpenoids isolated from Salvia languidula with an unusual epoxy spiro \u03b3-lactone","volume":"33","author":"Esquivel","year":"1992","journal-title":"Tetrahedron Lett."},{"key":"ref_220","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1016\/j.tetlet.2011.02.003","article-title":"Salvileucalin C, a novel rearranged neoclerodane diterpene from Salvia leucantha","volume":"52","author":"Aoyagi","year":"2011","journal-title":"Tetrahedron Lett."},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1007\/s43450-022-00332-z","article-title":"Amarisolide H and 15-epi-Amarisolide H, two diterpenoid glucosides from Salvia circinnata","volume":"32","author":"Bautista","year":"2022","journal-title":"Rev. Bras. Farmacogn."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/31\/18\/3287\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:52:07Z","timestamp":1789566727000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/31\/18\/3287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,16]]},"references-count":221,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["molecules31183287"],"URL":"https:\/\/doi.org\/10.3390\/molecules31183287","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,16]]}}}