{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T05:03:04Z","timestamp":1790053384416,"version":"4.0.1"},"reference-count":129,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Science and Technology, Taiwan","award":["115-2221-E-002-048-MY3"],"award-info":[{"award-number":["115-2221-E-002-048-MY3"]}],"id":[{"id":"https:\/\/ror.org\/02kv4zf79","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Ministry of Science and Technology, Taiwan","award":["115-2321-B-002-013"],"award-info":[{"award-number":["115-2321-B-002-013"]}],"id":[{"id":"https:\/\/ror.org\/02kv4zf79","id-type":"ROR","asserted-by":"crossref"}]},{"award":["115-2221-E-002-048-MY3"],"award-info":[{"award-number":["115-2221-E-002-048-MY3"]}],"id":[{"id":"https:\/\/ror.org\/02kv4zf79","id-type":"ROR","asserted-by":"publisher"}]},{"award":["115-2321-B-002-013"],"award-info":[{"award-number":["115-2321-B-002-013"]}],"id":[{"id":"https:\/\/ror.org\/02kv4zf79","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Escalating environmental concerns over petroleum-based plastics have driven growing interest in seaweed-derived polysaccharides and bioactive compounds as sustainable alternatives for biodegradable packaging. This review synthesizes recent advances in seaweed-based packaging, particularly related to seafood preservation. It covers the development of edible films and coatings, innovations in active and smart packaging, and the creation of multilayer multifunctional systems. The review highlights key applications that demonstrate the effectiveness of seaweed-based materials in delaying microbial spoilage, reducing lipid oxidation, preserving sensory quality, and extending the shelf life of seafood. Additionally, this review addresses food safety and regulatory considerations and provides a detailed examination of major barriers to commercial adoption, particularly variability in composition depending on environmental, physiological, extraction, and geographical factors, high production costs associated with polysaccharide extraction and purification, insufficient pilot- and industrial-scale validation, and the lack of standardized processing protocols.<\/jats:p>","DOI":"10.3390\/molecules31183317","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T14:12:09Z","timestamp":1789999929000},"page":"3317","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bioactive Compounds from Seaweeds as Natural Preservatives for Seafood"],"prefix":"10.3390","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4269-7999","authenticated-orcid":false,"given":"Janine","family":"Ametin","sequence":"first","affiliation":[{"name":"Faculty of Food, Agriculture and Natural Resources, Asian Institute of Technology, Klong Luang, Bangkok 12120, Thailand"},{"name":"Fisheries Postharvest Research and Development Division, National Fisheries Research and Development Institute, Quezon City 1103, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2857-7579","authenticated-orcid":false,"given":"Anil Kumar","family":"Anal","sequence":"additional","affiliation":[{"name":"Faculty of Food, Agriculture and Natural Resources, Asian Institute of Technology, Klong Luang, Bangkok 12120, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muspirah","family":"Djalal","sequence":"additional","affiliation":[{"name":"Institute of Food Science and Technology, College of Bioresources and Agriculture, National Taiwan University, Taipei 10617, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9871-9071","authenticated-orcid":false,"given":"Yun-Hsin","family":"Lin","sequence":"additional","affiliation":[{"name":"Institute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Wen","family":"Lin","sequence":"additional","affiliation":[{"name":"Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan"},{"name":"Department of Medical Research, Chung Shan Medical University Hospital, Taichung 402, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0387-7804","authenticated-orcid":false,"given":"Kuan-Chen","family":"Cheng","sequence":"additional","affiliation":[{"name":"Institute of Food Science and Technology, College of Bioresources and Agriculture, National Taiwan University, Taipei 10617, Taiwan"},{"name":"Institute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan"},{"name":"Department of Optometry, Asia University, Taichung 413305, Taiwan"},{"name":"Department of Medical Research, China Medical University Hospital, Taichung 404327, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1111\/1541-4337.13117","article-title":"Application of smart packaging for seafood: A comprehensive review","volume":"22","author":"Salim","year":"2023","journal-title":"Compr. 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