{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:57:32Z","timestamp":1790744252858,"version":"4.1.0"},"reference-count":19,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Heilongjiang Provincial Education Department","award":["2023-KYYWF-1063"],"award-info":[{"award-number":["2023-KYYWF-1063"]}]},{"name":"Heilongjiang Province Ecological and Environmental Protection Scientific Research Project","award":["HST2025S010"],"award-info":[{"award-number":["HST2025S010"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Peroxide is a vital oxidant that can quickly kill bacteria, viruses, and fungi in food and ensure food safety. However, excessive intake will stimulate the gastrointestinal tract, cause abdominal pain and vomiting, and its strong oxidation will also destroy the vitamin and protein structure in food. Cerium-based nanomaterials exhibit good biocompatibility and strong chemical stability, and have significant application value in biological detection. Cu nanoparticles were deposited on the surface of a glassy carbon electrode (GCE) by potentiostatic deposition. The Ce3+\/PA-Cu2+@Cu\/GCE sensor was constructed by etching and complexing Cu2+ with phytic acid (PA) to form a PA-Cu3+ coordination film. By X-ray diffraction (XRD) and Fourier Transform Infrared (FT-IR), the structure of composite material on the electrode surface was characterized. Electrochemical test results: Cu time of electrodeposition 700 s, PA embellishment 60 min, Ce3+ coordination 60 min, and H2O2 Reaction 15 min. The detection linearity range of the sensor for hydrogen peroxide is 0.1\u2013100 \u03bcmol\/L, detection limit is 0.89 \u03bcmol\/L, and there was good selectivity, sensitivity and reproducibility (RSD = 1.013%) and stability (retention of 84% response at 28 days).<\/jats:p>","DOI":"10.3390\/molecules31193448","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T11:35:59Z","timestamp":1790595359000},"page":"3448","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Peroxidase Sensor Based on Electroactive Ce3+-Phytic Acid-Cu2+@Cu Composite"],"prefix":"10.3390","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2927-5879","authenticated-orcid":false,"given":"Boxin","family":"Dou","sequence":"first","affiliation":[{"name":"Key Laboratory of Food Science and Engineering of Heilongjiang Ordinary Higher Colleges, College of Food Engineering, Harbin University of Commerce, Harbin 150000, China"},{"name":"Postdoctoral Research Workstation of Northeast Asia Service Outsourcing Research Center, Harbin University of Commerce, Harbin 150028, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Minrong","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Food Science and Engineering of Heilongjiang Ordinary Higher Colleges, College of Food Engineering, Harbin University of Commerce, Harbin 150000, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"}]},{"given":"Mingyu","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Food Science and Engineering of Heilongjiang Ordinary Higher Colleges, College of Food Engineering, Harbin University of Commerce, Harbin 150000, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Food Science and Engineering of Heilongjiang Ordinary Higher Colleges, College of Food Engineering, Harbin University of Commerce, Harbin 150000, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"project-administration","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6937-5458","authenticated-orcid":false,"given":"Jianhui","family":"Jia","sequence":"additional","affiliation":[{"name":"College of Life Science and Technology, Mudanjiang Normal University, Mudanjiang 157011, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Food Science and Engineering of Heilongjiang Ordinary Higher Colleges, College of Food Engineering, Harbin University of Commerce, Harbin 150000, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.foodcont.2007.01.004","article-title":"Determination of hydrogen peroxide residues in aseptically packaged beverages using an amperometric sensor based on a palladium electrode","volume":"19","author":"Hsu","year":"2007","journal-title":"Food Control"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"10356","DOI":"10.3390\/s91210356","article-title":"Aptamer-Functionalized Nano-Biosensors","volume":"9","author":"Chiu","year":"2009","journal-title":"Sensors"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"112432","DOI":"10.1016\/j.bios.2020.112432","article-title":"Ultrasensitive nonenzymatic electrochemical glucose sensor based on gold nanoparticles and molecularly imprinted polymers","volume":"165","author":"Sehit","year":"2020","journal-title":"Biosens. 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