{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:00:06Z","timestamp":1791198006606,"version":"4.1.0"},"reference-count":39,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:00:00Z","timestamp":1791072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"university synergy innovation program of Anhui province","award":["GXXT-2023-054"],"award-info":[{"award-number":["GXXT-2023-054"]}]},{"name":"Key Scientific Research Project of Anhui Provincial Universities","award":["2024AH051738"],"award-info":[{"award-number":["2024AH051738"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Polygonatum cyrtonema Hua in Jiuhua Mountain (JHPCH) is a nationally recognized geographically indicated medicinal plant known for its bioactive polysaccharides with diverse pharmacological activities. This study isolated a homogeneous polysaccharide JPCP-70-0 from JHPCH via hot water extraction, ethanol precipitation, and chromatographic purification. Structural characterization by GC-MS, FT-IR, and NMR identified it as a neutral fructan (2.88 \u00d7 104 Da) with Glc\/Fru (6.65%\/93.35%), a backbone of \u21921)-\u03b2-D-Fruf-(2\u2192, and side chains of \u21926)-\u03b2-D-Fruf-(2\u2192). Using Caenorhabditis elegans as a model, we evaluated JPCP-70-0\u2019s effects on nematode growth. Results showed concentration-dependent regulation: low concentrations promoted growth, locomotion, feeding, and reproduction, while high concentrations induced developmental inhibition and reduced activity. This work provides a theoretical basis for the rational development of JHPCH resources.<\/jats:p>","DOI":"10.3390\/molecules31193542","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:02:27Z","timestamp":1791194547000},"page":"3542","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Polygonatum cyrtonema Hua in Jiuhua Mountain: Structural Characterization and Biological Activity"],"prefix":"10.3390","volume":"31","author":[{"given":"Xueqing","family":"Geng","sequence":"first","affiliation":[{"name":"School of Bioengineering, Huainan Normal University, Huainan 232038, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"}]},{"given":"Xingchi","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Bioengineering, Huainan Normal University, Huainan 232038, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"software","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"}]},{"given":"Yun","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Bioengineering, Huainan Normal University, Huainan 232038, China"},{"name":"Key Laboratory of Bioresource and Environmental Biotechnology of Anhui Higher Education Institutes, Huainan Normal University, Huainan 232038, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"}]},{"given":"Ting","family":"Yao","sequence":"additional","affiliation":[{"name":"College of Life and Environmental Sciences, Huangshan University, Huangshan 245700, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"}]},{"given":"Zhuoting","family":"Gan","sequence":"additional","affiliation":[{"name":"School of Tourism, Huangshan University, Huangshan 245700, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,10,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Shang, X., Wang, J., Zhang, H., Hu, G., Han, Y., Sun, Y., Zhou, X., Kong, X., Shao, T., and Wang, G. 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