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A SCI is a devastating event affecting both sensory and motor functions. Due to better care, the SCI population is changing, with a greater proportion retaining impaired ambulatory function. Optimizing ambulatory function after SCI remains challenging. To investigate factors influencing optimal ambulation, a multi-professional research project was grounded with expertise from clinical rehabilitation, neurophysiology, and biomechanical engineering from Karolinska Institutet, the Spinalis Unit at Aleris Rehab Station (Sweden\u2019s largest center for specialized neurorehabilitation), and the Promobilia MoveAbility Lab at KTH Royal Institute of Technology. Ambulatory adults with paraplegia will be consecutively invited to participate. Muscle strength, sensitivity, and spasticity will be assessed, and energy expenditure, 3D movements, and muscle function (EMG) during gait and submaximal contractions will be analyzed. Innovative computational modeling and data-driven analyses will be performed, including the identification of clusters of similar movement patterns among the heterogeneous population and analyses that study the link between complex sensorimotor function and movement performance. These results may help optimize ambulatory function for persons with SCI and decrease the risk of secondary conditions during gait with a life-long perspective.<\/jats:p>","DOI":"10.3390\/mps7030039","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T15:05:01Z","timestamp":1715007901000},"page":"39","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A Protocol for Comprehensive Analysis of Gait in Individuals with Incomplete Spinal Cord Injury"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5540-342X","authenticated-orcid":false,"given":"Emelie","family":"Butler Forslund","sequence":"first","affiliation":[{"name":"Department of Neurobiology, Care Science and Society, Karolinska Institutet, 141 83 Stockholm, Sweden"},{"name":"Aleris Rehab Station R&D Unit, 169 89 Solna, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4571-1984","authenticated-orcid":false,"given":"Minh Tat Nhat","family":"Truong","sequence":"additional","affiliation":[{"name":"KTH MoveAbility, Department of Engineering Mechanics, KTH Royal Institute of Technology, 100 44 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoli","family":"Wang","sequence":"additional","affiliation":[{"name":"KTH MoveAbility, Department of Engineering Mechanics, KTH Royal Institute of Technology, 100 44 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5ke","family":"Seiger","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care Science and Society, Karolinska Institutet, 141 83 Stockholm, Sweden"},{"name":"Aleris Rehab Station R&D Unit, 169 89 Solna, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5417-5939","authenticated-orcid":false,"given":"Elena M.","family":"Gutierrez-Farewik","sequence":"additional","affiliation":[{"name":"KTH MoveAbility, Department of Engineering Mechanics, KTH Royal Institute of Technology, 100 44 Stockholm, Sweden"},{"name":"Department of Women\u2019s and Children\u2019s Health, Karolinska Institutet, 171 77 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,5,4]]},"reference":[{"key":"ref_1","unstructured":"Chhabra, H.S. 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