{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T23:18:07Z","timestamp":1785280687932,"version":"3.55.0"},"reference-count":99,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nanomaterials"],"abstract":"<jats:p>Decorating photocatalysts with noble metal nanoparticles (e.g., Pt) often increases the catalysts\u2019 photocatalytic activity and biomedical properties. Here, a simple and inexpensive method has been developed to prepare a Pt-Ag3PO4\/CdS\/chitosan composite, which was characterized and used for the visible light-induced photocatalytic and antibacterial studies. This synthesized composite showed superior photocatalytic activity for methylene blue degradation as a hazardous pollutant (the maximum dye degradation was observed in 90 min of treatment) and killing of Gram positive bacterial (Staphylococcus aureus and Bacillus cereus) as well as Gram negative bacteria (Klebsiella pneumoniae, Salmonella typhimurium, Escherichia coli, and Pseudomonas aeruginosa) under visible light irradiation. The antibacterial activity of CdS, CdS\/Ag3PO4, and Pt-Ag3PO4\/CdS\/chitosan against E. coli, Pseudomonas aeruginosa, Salmonella typhimurium, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus cereus showed the zone of inhibition (mm) under visible light and under dark conditions at a concentration of 20 \u00b5g mL\u22121. Furthermore, the cell viability of the CdS\/chitosan, Ag3PO4, Ag3PO4\/CdS\/chitosan, and Pt-Ag3PO4\/CdS\/chitosan were investigated on the human embryonic kidney 293 cells (HEK-293), Henrietta Lacks (HeLa), human liver cancer cell line (HepG2), and pheochromocytoma (PC12) cell lines. In addition, the results indicated that the photodegradation rate for Pt-Ag3PO4\/CdS\/chitosan is 3.53 times higher than that of CdS and 1.73 times higher than that of the CdS\/Ag3PO4 composite. Moreover, Pt-Ag3PO4\/CdS\/chitosan with an optimal amount of CdS killed large areas of different bacteria and different cells separately in a shorter time period under visible-light irradiation, which shows significantly higher efficiency than pure CdS and other CdS\/Ag3PO4 composites. The superb performances of this composite are attributed to its privileged properties, such as retarded recombination of photoinduced electron\/hole pairs and a large specific surface area, making Pt-Ag3PO4\/CdS\/chitosan a valuable composite that can be deployed for a range of important applications, such as visible light-induced photocatalysis and antibacterial activity.<\/jats:p>","DOI":"10.3390\/nano10112320","type":"journal-article","created":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T08:18:23Z","timestamp":1606119503000},"page":"2320","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Novel Pt-Ag3PO4\/CdS\/Chitosan Nanocomposite with Enhanced Photocatalytic and Biological Activities"],"prefix":"10.3390","volume":"10","author":[{"given":"Mahsa","family":"Kiani","sequence":"first","affiliation":[{"name":"Department of Chemistry, Sharif University of Technology, P.O. Box 11155-3516, Tehran 14155-6451, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojtaba","family":"Bagherzadeh","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Sharif University of Technology, P.O. Box 11155-3516, Tehran 14155-6451, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reyhaneh","family":"Kaveh","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Sharif University of Technology, P.O. Box 11155-3516, Tehran 14155-6451, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6945-8541","authenticated-orcid":false,"given":"Navid","family":"Rabiee","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Sharif University of Technology, P.O. Box 11155-3516, Tehran 14155-6451, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0374-2141","authenticated-orcid":false,"given":"Yousef","family":"Fatahi","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14155-6451, Iran"},{"name":"Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14155-6451, Iran"},{"name":"Universal Scientific Education and Research Network (USERN), Tehran 15875-4413, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0694-7556","authenticated-orcid":false,"given":"Rassoul","family":"Dinarvand","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14155-6451, Iran"},{"name":"Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14155-6451, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6952-7359","authenticated-orcid":false,"given":"Ho Won","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, Research Institute of Advanced Materials, Seoul National University, Seoul 08826, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1416-6805","authenticated-orcid":false,"given":"Mohammadreza","family":"Shokouhimehr","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, Research Institute of Advanced Materials, Seoul National University, Seoul 08826, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9731-6228","authenticated-orcid":false,"given":"Rajender S.","family":"Varma","sequence":"additional","affiliation":[{"name":"Regional Center of Advanced Technologies and Materials, Palacky University, \u0160lechtitel\u016f 27, 78371 Olomouc, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1080\/21691401.2016.1260576","article-title":"Novel antibacterial polymeric nanocomposite for smart co-delivery of anticancer drugs","volume":"45","author":"Zakerzadeh","year":"2017","journal-title":"Artif. 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