{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:21:40Z","timestamp":1784002900118,"version":"3.55.0"},"reference-count":58,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T00:00:00Z","timestamp":1649289600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","award":["2017-70001-25984"],"award-info":[{"award-number":["2017-70001-25984"]}],"id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006597","name":"Florida State University","doi-asserted-by":"publisher","award":["Collaborative Collision focused on Defense"],"award-info":[{"award-number":["Collaborative Collision focused on Defense"]}],"id":[{"id":"10.13039\/100006597","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DMR-1644779"],"award-info":[{"award-number":["DMR-1644779"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000015","name":"United States Department of Energy","doi-asserted-by":"publisher","award":["DE-AC02-06CH11357"],"award-info":[{"award-number":["DE-AC02-06CH11357"]}],"id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nanomaterials"],"abstract":"<jats:p>Magnetic-core\/gold-shell nanoparticles (MAuNPs) are of interest for enabling rapid and portable detection of trace adulterants in complex media. Gold coating provides biocompatibility and facile functionalization, and a magnetic core affords analyte concentration and controlled deposition onto substrates for surface-enhanced Raman spectroscopy. Iron oxide cores were synthesized and coated with gold by reduction of HAuCl4 by NH2OH. MAuNPs were grafted with polyethylene glycol (PEG) and\/or functionalized with 4-mercaptobenzoic acid (4-MBA) and examined using a variety of microscopic, spectroscopic, magnetometric, and scattering techniques. For MAuNPs grafted with both PEG and 4-MBA, the order in which they were grafted impacted not only the graft density of the individual ligands, but also the overall graft density. Significant Raman signal enhancement of the model analyte, 4-MBA, was observed. This enhancement demonstrates the functionality of MAuNPs in direct detection of trace contaminants. The magnetic deposition rate of MAuNPs in chloroform and water was explored. The presence of 4-MBA slowed the mass deposition rate, and it was postulated that the rate disparity originated from differing NP-substrate surface interactions. These findings emphasize the importance of ligand choice in reference to the medium, target analyte, and substrate material, as well as functionalization procedure in the design of similar sensing platforms.<\/jats:p>","DOI":"10.3390\/nano12081253","type":"journal-article","created":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T21:08:22Z","timestamp":1649365702000},"page":"1253","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Magnetic-Core\/Gold-Shell Nanoparticles for the Detection of Hydrophobic Chemical Contaminants"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8273-2883","authenticated-orcid":false,"given":"Anna M.","family":"Mills","sequence":"first","affiliation":[{"name":"Chemical and Biomedical Engineering Department, Florida A&M University\u2014Florida State University College of Engineering, Tallahassee, FL 32310, USA"},{"name":"Aero-Propulsion, Mechatronics, and Energy Center, Florida State University, Tallahassee, FL 32310, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4619-8932","authenticated-orcid":false,"given":"Joseph","family":"Strzalka","sequence":"additional","affiliation":[{"name":"Argonne National Laboratory, X-ray Science Division, Lemont, IL 60439, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bernat","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Integrative Physiology, Florida State University, Tallahassee, FL 32306, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6853-5381","authenticated-orcid":false,"given":"Qinchun","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Integrative Physiology, Florida State University, Tallahassee, FL 32306, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Daniel T.","family":"Hallinan","sequence":"additional","affiliation":[{"name":"Chemical and Biomedical Engineering Department, Florida A&M University\u2014Florida State University College of Engineering, Tallahassee, FL 32310, USA"},{"name":"Aero-Propulsion, Mechatronics, and Energy Center, Florida State University, Tallahassee, FL 32310, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"120781","DOI":"10.1016\/j.talanta.2020.120781","article-title":"Nanoparticle-assisted pyrrolidonyl arylamidase assay for a culture-free Group A Streptococcus pyogenes detection with image analysis","volume":"212","author":"Tamer","year":"2020","journal-title":"Talanta"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"30736","DOI":"10.3390\/s151229826","article-title":"Portable Nanoparticle-Based Sensors for Food Safety Assessment","volume":"15","author":"Hayat","year":"2015","journal-title":"Sensors"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"5706","DOI":"10.1039\/c2cs35138b","article-title":"Fingerprinting food: Current technologies for the detection of food adulteration and contamination","volume":"41","author":"Ellis","year":"2012","journal-title":"Chem. 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