{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T15:06:58Z","timestamp":1788534418381,"version":"build-2803163510"},"reference-count":44,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T00:00:00Z","timestamp":1690156800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FONDEF","award":["ID20I10040"],"award-info":[{"award-number":["ID20I10040"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nanomaterials"],"abstract":"<jats:p>In this work, copper (II) ions were saturated and copper oxide nanoparticles (CuO NPs) were supported in natural zeolite from Chile; this was achieved by making the adsorbent material come into contact with a copper ion precursor solution and using mechanical agitation, respectively. The kinetic and physicochemical process of the adsorption of copper ions in the zeolite was studied, as well as the effect of the addition of CuO NPs on the antibacterial properties. The results showed that the saturation of copper (II) ions in the zeolite is an efficient process, obtaining a 27 g L\u22121 concentration of copper ions in a time of 30 min. The TEM images showed that a good dispersion of the CuO NPs was obtained via mechanical stirring. The material effectively inhibited the growth of Gram-negative and Gram-positive bacteria that have shown resistance to methicillin and carbapenem. Furthermore, the zeolite saturated with copper at the same concentration had a better bactericidal effect than the zeolite supported with CuO NPs. The results suggested that the ease of processing and low cost of copper (II) ion-saturated zeolitic material could potentially be used for dental biomedical applications, either directly or as a bactericidal additive for 3D printing filaments.<\/jats:p>","DOI":"10.3390\/nano13142140","type":"journal-article","created":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T01:08:11Z","timestamp":1690160891000},"page":"2140","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Study of the Antibacterial Capacity of a Biomaterial of Zeolites Saturated with Copper Ions (Cu2+) and Supported with Copper Oxide (CuO) Nanoparticles"],"prefix":"10.3390","volume":"13","author":[{"given":"Lina","family":"Romero","sequence":"first","affiliation":[{"name":"Interdisciplinary Group of Applied Nanotechnology (GINA), Hybrid Materials Laboratory (HML), Department of Materials Engineering (DIMAT), Faculty of Engineering, Universidad de Concepci\u00f3n, 270 Edmundo Larenas, Box 160-C, Concepcion 4070409, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6604-1409","authenticated-orcid":false,"given":"Nicolas","family":"Araya","sequence":"additional","affiliation":[{"name":"Interdisciplinary Group of Applied Nanotechnology (GINA), Hybrid Materials Laboratory (HML), Department of Materials Engineering (DIMAT), Faculty of Engineering, Universidad de Concepci\u00f3n, 270 Edmundo Larenas, Box 160-C, Concepcion 4070409, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1874-9696","authenticated-orcid":false,"given":"Daniel","family":"Palacio","sequence":"additional","affiliation":[{"name":"Departamento de Pol\u00edmeros, Facultad de Ciencias Qu\u00edmicas, Universidad de Concepci\u00f3n, 129 Edmundo Larenas, Concepcion 4070409, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6715-6286","authenticated-orcid":false,"given":"Gabriela","family":"S\u00e1nchez-Sanhueza","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Dentistry, Universidad de Concepci\u00f3n, Concepcion 4070409, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"P\u00e9rez-Tijerina","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias F\u00edsico-Matem\u00e1ticas, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, San Nicolas de los Garza, Nuevo Leon 66451, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Sol\u00eds","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias F\u00edsico-Matem\u00e1ticas, Universidad Aut\u00f3noma de Nuevo Le\u00f3n, San Nicolas de los Garza, Nuevo Leon 66451, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5826-4979","authenticated-orcid":false,"given":"Manuel","family":"Mel\u00e9ndrez","sequence":"additional","affiliation":[{"name":"Interdisciplinary Group of Applied Nanotechnology (GINA), Hybrid Materials Laboratory (HML), Department of Materials Engineering (DIMAT), Faculty of Engineering, Universidad de Concepci\u00f3n, 270 Edmundo Larenas, Box 160-C, Concepcion 4070409, Chile"},{"name":"Unidad de Desarrollo Tecnol\u00f3gico, 2634 Av. Cordillera, Parque Industrial Coronel, Box 4051, Concepcion 4191996, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7448-4798","authenticated-orcid":false,"given":"Carlos","family":"Medina","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering (DIM), Faculty of Engineering, Universidad de Concepci\u00f3n, Edmundo Larenas 270, Concepcion 4070409, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.3389\/fphar.2018.01350","article-title":"Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in Vivo","volume":"9","year":"2018","journal-title":"Front. 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