{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:05:42Z","timestamp":1792073142822,"version":"4.4.0"},"reference-count":52,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:00:00Z","timestamp":1736380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Science and Technology Innovation Fund for College Students at Yangzhou University"},{"name":"Testing Center of Yangzhou University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nanomaterials"],"abstract":"<jats:p>In this study, copper nanoparticles with an average particle size of 2\u20134 nm were synthesized using the green extract of Lonicera japonica Thunb. The catalytic activity and dye degradation efficiency of Cu NPs were evaluated using ultraviolet spectroscopy. To confirm that Cu NPs can continuously remove organic dyes, this study used Cu\/Lj-C composite material adsorbed on cotton balls as a simulated bed to study the cyclic catalytic activity of Cu NPs for the reduction of methylene blue by sodium borohydride (NaBH4). The experiment showed that after multiple cycles, it can also quickly and effectively reduce methylene blue. To evaluate the toxicity of Cu NPs, experiments were conducted using HUVEC and MC3T3-E1 cells. The median lethal doses (LD50) were 37.64 \u00b5g\/mL and 7.50 \u00b5g\/mL. The synthesized Cu NPs also exhibited antibacterial efficacy against Aspergillus niger (fungus), Staphylococcus aureus (Gram-positive bacteria), Escherichia coli (Gram-negative bacteria), and Candida albicans (yeast).<\/jats:p>","DOI":"10.3390\/nano15020091","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T07:59:42Z","timestamp":1736409582000},"page":"91","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Green Synthesis of Copper Nanoparticles from the Aqueous Extract of Lonicera japonica Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity"],"prefix":"10.3390","volume":"15","author":[{"given":"Weijie","family":"Yu","sequence":"first","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyi","family":"Tang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunxia","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3297-7281","authenticated-orcid":false,"given":"Xuesong","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5652-424X","authenticated-orcid":false,"given":"Peizhi","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"149126","DOI":"10.1016\/j.apsusc.2021.149126","article-title":"Iron oxide nanoparticles obtained from steel waste recycling as a green alternative for Congo red dye fast adsorption","volume":"546","author":"Borth","year":"2021","journal-title":"Appl. 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