{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T01:38:31Z","timestamp":1790213911432,"version":"4.1.0"},"reference-count":71,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["22206095"],"award-info":[{"award-number":["22206095"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Fundamental Research Funds for the Central Universities","award":["FRF-TP-22-087A1"],"award-info":[{"award-number":["FRF-TP-22-087A1"]}]},{"name":"the Fundamental Research Funds for the Central Universities","award":["FRF-BD-25-003"],"award-info":[{"award-number":["FRF-BD-25-003"]}]},{"name":"the National Key R&D Program of China","award":["2023YFB3810800"],"award-info":[{"award-number":["2023YFB3810800"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nanomaterials"],"abstract":"<jats:p>Estimating the adsorption data and understanding the adsorption behavior and mechanism of organic pollutants on nanoplastics are crucial for assessing their ecological risks. Herein, in silico techniques, i.e., grand canonical Monte Carlo simulations, density functional theory computations, and quantitative structure activity relationship (QSAR) modeling, were integrated to examine the adsorption of 39 representative aliphatic and aromatic compounds and nine emerging pollutants (brominated flame retardants and phosphorus flame retardants) onto 12 different nanoplastics under atmospheric conditions. Three QSAR models were constructed to predict the adsorption equilibrium constant (logK) for polyethylene, polyoxymethylene, and polyvinyl alcohol nanoplastics individually, along with 12 QSAR models for separately estimating adsorption capacities (Cm) on different nanoplastics. Furthermore, a novel multi-dimensional prediction model was developed, enabling simultaneous, high-throughput prediction of adsorption capacities across multiple nanoplastics and pollutants with a single input. These results revealed that van der Waals and electrostatic interactions serve as the primary driving forces for the adsorption. The novel multi-dimensional prediction model facilitates rapid and comprehensive assessment of pollutant\u2013nanoplastic interactions with one-click, and paves the way for improved risk evaluations and advancing predictive environmental research.<\/jats:p>","DOI":"10.3390\/nano16030178","type":"journal-article","created":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T15:04:46Z","timestamp":1769612686000},"page":"178","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["In Silico Models for Predicting Adsorption of Organic Pollutants on Atmospheric Nanoplastics by Combining Grand Canonical Monte Carlo\/Density Functional Theory and Quantitative Structure Activity Relationship Approach"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3101-0597","authenticated-orcid":false,"given":"Ya","family":"Wang","sequence":"first","affiliation":[{"name":"School of Energy and Environmental Engineering, University of Science and Technology Beijing, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honghong","family":"Yi","sequence":"additional","affiliation":[{"name":"School of Energy and Environmental Engineering, University of Science and Technology Beijing, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Li","sequence":"additional","affiliation":[{"name":"Engineering Laboratory for Water Pollution Control and Resources Recovery, School of Environment, Northeast Normal University, Changchun 130117, China"},{"name":"State Environmental Protection Key Laboratory of Wetland Ecology and Vegetation Restoration, School of Environment, Northeast Normal University, Changchun 130117, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolong","family":"Tang","sequence":"additional","affiliation":[{"name":"School of Energy and Environmental Engineering, University of Science and Technology Beijing, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Energy and Environmental Engineering, University of Science and Technology Beijing, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongfang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Puerto Rico, San Juan, PR 00931, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e1700782","DOI":"10.1126\/sciadv.1700782","article-title":"Production, use, and fate of all plastics ever made","volume":"3","author":"Geyer","year":"2017","journal-title":"Sci. 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