{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:25:26Z","timestamp":1793111126702,"version":"4.5.0"},"reference-count":128,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Italian Ministry of University and Research","award":["CN00000041"],"award-info":[{"award-number":["CN00000041"]}]},{"name":"Italian Ministry of University and Research","award":["PRIN P2022W577H_001: CUP F53D23011320001"],"award-info":[{"award-number":["PRIN P2022W577H_001: CUP F53D23011320001"]}]},{"name":"Italian Ministry of University and Research","award":["\u201cCal-HubRia\u201d-T4-AN-09"],"award-info":[{"award-number":["\u201cCal-HubRia\u201d-T4-AN-09"]}]},{"name":"Italian Ministry of University and Research","award":["PNRR-MAD-2022-12376814"],"award-info":[{"award-number":["PNRR-MAD-2022-12376814"]}]},{"name":"Italian Ministry of Health","award":["CN00000041"],"award-info":[{"award-number":["CN00000041"]}]},{"name":"Italian Ministry of Health","award":["PRIN P2022W577H_001: CUP F53D23011320001"],"award-info":[{"award-number":["PRIN P2022W577H_001: CUP F53D23011320001"]}]},{"name":"Italian Ministry of Health","award":["\u201cCal-HubRia\u201d-T4-AN-09"],"award-info":[{"award-number":["\u201cCal-HubRia\u201d-T4-AN-09"]}]},{"name":"Italian Ministry of Health","award":["PNRR-MAD-2022-12376814"],"award-info":[{"award-number":["PNRR-MAD-2022-12376814"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ncRNA"],"abstract":"<jats:p>Cardiomyopathies are the structural and functional disorders of the myocardium. Etiopathogenesis is complex and involves an interplay of genetic, environmental, and lifestyle factors eventually leading to myocardial abnormalities. It is known that non-coding (Nc) RNAs, including micro (mi)-RNAs and long non-coding (lnc) RNAs, play a crucial role in regulating gene expression. Several studies have explored the role of miRNAs in the development of various pathologies, including heart diseases. In this review, we analyzed various patterns of ncRNAs expressed in the most common cardiomyopathies: dilated cardiomyopathy, hypertrophic cardiomyopathy and arrhythmogenic cardiomyopathy. Understanding the role of different ncRNAs implicated in cardiomyopathic processes may contribute to the identification of potential therapeutic targets and novel risk stratification models based on gene expression. The analysis of ncRNAs may also be helpful to unveil the molecular mechanisms subtended to these diseases.<\/jats:p>","DOI":"10.3390\/ncrna10060053","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T09:07:04Z","timestamp":1729674424000},"page":"53","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Cardiomyopathies: The Role of Non-Coding RNAs"],"prefix":"10.3390","volume":"10","author":[{"given":"Nicole","family":"Carabetta","sequence":"first","affiliation":[{"name":"Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Siracusa","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4774-0888","authenticated-orcid":false,"given":"Isabella","family":"Leo","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Panuccio","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy"},{"name":"Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charit\u00e9 Berlin, 12200 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2832-8150","authenticated-orcid":false,"given":"Antonio","family":"Strangio","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanda","family":"Sabatino","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4915-5084","authenticated-orcid":false,"given":"Daniele","family":"Torella","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5388-942X","authenticated-orcid":false,"given":"Salvatore","family":"De Rosa","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1093\/eurheartj\/ehm342","article-title":"Classification of the Cardiomyopathies: A Position Statement from the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases","volume":"29","author":"Elliott","year":"2008","journal-title":"Eur. 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