{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:37:40Z","timestamp":1777041460532,"version":"3.51.4"},"reference-count":43,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology International"],"abstract":"<jats:p>We present a case of a patient with positive N-methyl-D-aspartate receptor (NMDAR) IgG antibodies in their serum and cerebrospinal fluid (CSF) associated with neuroborreliosis. Clinically, the patient presented with symptoms of confusion, as well as behavioral and speech impairments. Regardless of antibacterial treatment, no significant improvement was achieved. Methylprednisolone provided a marked improvement in the patient\u2019s clinical signs and CSF findings. The screening did not reveal any underlying neoplasm. Taking into account the marked clinical improvement after treatment with glucocorticosteroids, we suggest that NMDAR encephalitis is a possible autoimmune complication in neuroborreliosis patients requiring additional immunotherapy.<\/jats:p>","DOI":"10.3390\/neurolint13040048","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T21:39:29Z","timestamp":1632865169000},"page":"487-496","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Lyme Disease and Associated NMDAR Encephalitis: A Case Report and Literature Review"],"prefix":"10.3390","volume":"13","author":[{"given":"Natalja","family":"Predkele","sequence":"first","affiliation":[{"name":"Department of Neurology, Paul Stradins Clinical University Hospital, 13 Pilsonu St., LV-1002 Riga, Latvia"},{"name":"Department of Neurology and Neurosurgery, Riga Stradins University, 16 Dzirciema St., LV-1007 Riga, Latvia"},{"name":"Faculty of Residency, Riga Stradins University, 16 Dzirciema St., LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2195-0916","authenticated-orcid":false,"given":"J\u0101nis","family":"Mednieks","sequence":"additional","affiliation":[{"name":"Department of Neurology, Paul Stradins Clinical University Hospital, 13 Pilsonu St., LV-1002 Riga, Latvia"},{"name":"Department of Neurology and Neurosurgery, Riga Stradins University, 16 Dzirciema St., LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Tanaka, K., Kawamura, M., Sakimura, K., and Kato, N. 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