{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:42:00Z","timestamp":1760150520395,"version":"build-2065373602"},"reference-count":50,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:00Z","timestamp":1701216000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology International"],"abstract":"<jats:p>Neuromonitoring is a critical tool for emergency rooms and intensive care units to promptly identify and treat brain injuries. The case report of a patient with status epilepticus necessitating orotracheal intubation and intravenous lorazepam administration is presented. A pattern of epileptiform activity was detected in the left temporal region, and intravenous Acyclovir was administered based on the diagnostic hypothesis of herpetic meningoencephalitis. The neurointensivist opted for multimodal non-invasive bedside neuromonitoring due to the complexity of the patient\u2019s condition. A Brain4care (B4C) non-invasive intracranial compliance monitor was utilized alongside the assessment of an optic nerve sheath diameter (ONSD) and transcranial Doppler (TCD). Based on the collected data, a diagnosis of intracranial hypertension (ICH) was made and a treatment plan was developed. After the neurosurgery team\u2019s evaluation, a stereotaxic biopsy of the temporal lesion revealed a grade 2 diffuse astrocytoma, and an urgent total resection was performed. Research suggests that monitoring patients in a dedicated neurologic intensive care unit (Neuro ICU) can lead to improved outcomes and shorter hospital stays. In addition to being useful for patients with a primary brain injury, neuromonitoring may also be advantageous for those at risk of cerebral hemodynamic impairment. Lastly, it is essential to note that neuromonitoring technologies are non-invasive, less expensive, safe, and bedside-accessible approaches with significant diagnostic and monitoring potential for patients at risk of brain abnormalities. Multimodal neuromonitoring is a vital tool in critical care units for the identification and management of acute brain trauma as well as for patients at risk of cerebral hemodynamic impairment.<\/jats:p>","DOI":"10.3390\/neurolint15040090","type":"journal-article","created":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T03:53:52Z","timestamp":1701230032000},"page":"1403-1410","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Astrocytoma Mimicking Herpetic Meningoencephalitis: The Role of Non-Invasive Multimodal Monitoring in Neurointensivism"],"prefix":"10.3390","volume":"15","author":[{"given":"Uri Adrian Prync","family":"Flato","sequence":"first","affiliation":[{"name":"Hospital Samaritano Higien\u00f3polis\u2014Am\u00e9ricas Servi\u00e7os M\u00e9dicos, S\u00e3o Paulo 01232-010, Brazil"},{"name":"Hospital Israelita Albert Einstein, Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein, S\u00e3o Paulo 05652-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara Cristina de Abreu","family":"Pereira","sequence":"additional","affiliation":[{"name":"Hospital Samaritano Higien\u00f3polis\u2014Am\u00e9ricas Servi\u00e7os M\u00e9dicos, S\u00e3o Paulo 01232-010, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Alvares","family":"Costa","sequence":"additional","affiliation":[{"name":"Hospital Samaritano Higien\u00f3polis\u2014Am\u00e9ricas Servi\u00e7os M\u00e9dicos, S\u00e3o Paulo 01232-010, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Cairo","family":"Vilela","sequence":"additional","affiliation":[{"name":"Hospital Samaritano Higien\u00f3polis\u2014Am\u00e9ricas Servi\u00e7os M\u00e9dicos, S\u00e3o Paulo 01232-010, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Frigieri","sequence":"additional","affiliation":[{"name":"Medical Investigation Laboratory 62, School of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo 01246-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilton Jos\u00e9 Fernandes","family":"Cavalcante","sequence":"additional","affiliation":[{"name":"Hospital Samaritano Higien\u00f3polis\u2014Am\u00e9ricas Servi\u00e7os M\u00e9dicos, S\u00e3o Paulo 01232-010, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha Longhi Sim\u00f5es de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Hospital Samaritano Higien\u00f3polis\u2014Am\u00e9ricas Servi\u00e7os M\u00e9dicos, S\u00e3o Paulo 01232-010, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.nic.2022.07.002","article-title":"Structured Imaging Approach for Viral Encephalitis","volume":"33","author":"Ramli","year":"2023","journal-title":"Neuroimaging Clin. 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