{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:10:24Z","timestamp":1792627824147,"version":"4.5.0"},"reference-count":34,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology International"],"abstract":"<jats:p>Brachial plexus reconstruction (BPR) consists of the complex surgical restoration of nerve structures. To further understand the underlying motor cortex changes and evaluate neuroplasticity after a successful surgery, we performed a navigated transcranial magnetic stimulation (nTMS) study mapping the postoperative motor representation of the formerly plegic arm. We conducted a prospective nTMS study mapping the musculocutaneous nerve as a representative, prominent target of BPR including a patient (n = 8) and a control group (n = 10). Measurements like resting motor threshold (RMT), cortical motor area location, and size were taken. Mathematical analysis was performed using MATLAB 2022, statistical analysis was performed using SPSS 26, and nTMS mapping was performed using the Nexstim NBS 5.1 system. Mapping was feasible in seven out of eight patients. Median RMT on the affected hemisphere was 41% compared to 50% on the unaffected hemisphere and they were 37% and 36% on the left and right hemispheres of the control group. The motor area location showed a relocation of bicep brachii representation at the middle precentral gyrus of the corresponding contralateral hemisphere. Motor area size was increased compared to the control group and the patient\u2019s unaffected, ipsilateral hemisphere. Understanding cortical reorganization is important for potential future treatments like therapeutic nTMS. The issue of motor neuroplasticity in patients with brachial plexus lesions is worth exploring in further studies.<\/jats:p>","DOI":"10.3390\/neurolint16010016","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T11:25:55Z","timestamp":1706786755000},"page":"239-252","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Mapping Motor Neuroplasticity after Successful Surgical Brachial Plexus Reconstruction Using Navigated Transcranial Magnetic Stimulation (nTMS)"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9018-2458","authenticated-orcid":false,"given":"Gregor","family":"Durner","sequence":"first","affiliation":[{"name":"Peripheral Nerve Surgery Unit, Department of Neurosurgery, University of Ulm, Lindenallee 2, 89312 G\u00fcnzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ina","family":"Ulrich","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Ulm, Lindenallee 2, 89312 G\u00fcnzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Gerst","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Ulm, Lindenallee 2, 89312 G\u00fcnzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, University of Ulm, Lindenallee 2, 89312 G\u00fcnzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Rainer","family":"Wirtz","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Ulm, Lindenallee 2, 89312 G\u00fcnzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Antoniadis","sequence":"additional","affiliation":[{"name":"Peripheral Nerve Surgery Unit, Department of Neurosurgery, University of Ulm, Lindenallee 2, 89312 G\u00fcnzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Teresa","family":"Pedro","sequence":"additional","affiliation":[{"name":"Peripheral Nerve Surgery Unit, Department of Neurosurgery, University of Ulm, Lindenallee 2, 89312 G\u00fcnzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6653-701X","authenticated-orcid":false,"given":"Andrej","family":"Pala","sequence":"additional","affiliation":[{"name":"Peripheral Nerve Surgery Unit, Department of Neurosurgery, University of Ulm, Lindenallee 2, 89312 G\u00fcnzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF00227284","article-title":"Cortical motor representation of the ipsilateral hand and arm","volume":"100","author":"Wassermann","year":"1994","journal-title":"Exp. 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