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OSA is underdiagnosed in this population due to the lack of standardized methods and limited access to appropriate diagnostic technologies and appropriate equipment. Thus, this study aimed to investigate the presence and severity of sleep disorders, with a particular focus on OSA, in children and adolescents with CP compared to their typically developing peers. Methods: This observational, clinical, and prospective study included 28 children and adolescents with CP and 32 age- and sex-matched typically developing individuals. Sleep disturbances were assessed using the Sleep Disturbance Scale for Children (SDSC) and a high-resolution oximeter plus actigraphy combined with a cloud-based algorithm for the detection of obstructive sleep apnea (Biologix\u00ae system), which provided data on oxygen saturation, snoring, movement during sleep, and total sleep time. Results: According to the SDSC, 92% of children and adolescents with CP presented scores indicative of sleep disturbances, compared to 31% of typically developing individuals. SDB was the most prevalent subtype (64%) and overnight oximetry revealed that 100% of the CP group presented oxygen desaturation index (ODI) values consistent with a diagnosis of OSA. The CP group also exhibited significantly lower mean SpO2, longer snoring duration, shorter total sleep time, and prolonged sleep latency compared to the typically developing group. Conclusions: Children and adolescents with cerebral palsy (CP) exhibit a high prevalence of sleep disturbances, with increasing evidence indicating a significant occurrence of sleep-disordered breathing (SDB), particularly obstructive sleep apnea (OSA).<\/jats:p>","DOI":"10.3390\/neurolint17070101","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T05:00:37Z","timestamp":1751259637000},"page":"101","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sleep Disturbances and Obstructive Sleep Apnea in Children and Adolescents with Cerebral Palsy: An Observational Study"],"prefix":"10.3390","volume":"17","author":[{"given":"Isabella","family":"Meneses da Silva","sequence":"first","affiliation":[{"name":"Undergraduate Program in Speech, Language and Hearing Sciences, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Clara Helena","family":"do Couto","sequence":"additional","affiliation":[{"name":"Graduate Program in Health Sciences and Human Communication, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6937-7207","authenticated-orcid":false,"given":"Sanseray","family":"da Silveira Cruz-Machado","sequence":"additional","affiliation":[{"name":"Graduate Program in Health Sciences and Human Communication, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leticia Monteiro","family":"de Andrade","sequence":"additional","affiliation":[{"name":"Undergraduate Program in Speech, Language and Hearing Sciences, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Elisa Zuliani Stroppa","family":"Marques","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy and Occupational Therapy, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia Maria","family":"Giacheti","sequence":"additional","affiliation":[{"name":"Graduate Program in Health Sciences and Human Communication, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"},{"name":"Department of Speech, Language and Hearing Sciences, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiane Rodrigues","family":"Pedroni","sequence":"additional","affiliation":[{"name":"Graduate Program in Health Sciences and Human Communication, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"},{"name":"Department of Physiotherapy and Occupational Therapy, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana","family":"Pinato","sequence":"additional","affiliation":[{"name":"Graduate Program in Health Sciences and Human Communication, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"},{"name":"Department of Speech, Language and Hearing Sciences, Faculty of Philosophy and Sciences, S\u00e3o Paulo State University (UNESP), Campus Marilia 17525-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1017\/S001216220500112X","article-title":"Executive Committee for the Definition of Cerebral Palsy. 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