{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:43:56Z","timestamp":1791499436948,"version":"4.3.4"},"reference-count":32,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology International"],"abstract":"<jats:p>Background: Stroke is a major cerebrovascular disease characterized by disrupted cerebral blood flow, leading to neuronal damage and significant physical, cognitive, and emotional sequelae. While advancements in acute stroke management have improved survival rates, long-term complications such as cognitive impairment and depression continue to hinder recovery. This study addresses these dimensions within the context of ischemic stroke. Aim: The aim of this study was to analyze the cognitive status, functionality, and depressive symptoms in patients with ischemic stroke, exploring interrelations between cognitive, functional, and emotional outcomes to prioritize clinical interventions. Design: This was an analytical, observational, cohort, and prospective study. Methods: The study included 81 subjects diagnosed with ischemic stroke admitted to the Neurology Department of Lucus Augusti University Hospital. Data were collected at three time points\u2014admission, discharge, and follow-up\u2014using validated instruments such as the National Institutes of Health Stroke Scale, Mini-Mental State Examination, Barthel Index, and Beck Depression Inventory. Statistical analyses included Spearman\u2019s correlation, Kruskal\u2013Wallis, and Mann\u2013Whitney tests. Results: Patients with greater cognitive impairment at admission showed poorer functional recovery and higher depressive symptoms during follow-up. Depressive symptoms remained minimal in most cases, but correlations with cognitive and functional deficits were significant. NIHSS scores at admission strongly predicted both functional and emotional recovery, reinforcing its value in early prognosis and therapeutic planning. Conclusions: This study highlights the importance of integrating cognitive, functional, and emotional dimensions into stroke care protocols to optimize patient recovery and improve long-term outcomes.<\/jats:p>","DOI":"10.3390\/neurolint17100164","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T12:04:52Z","timestamp":1759925092000},"page":"164","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cognitive, Functional, and Emotional Recovery in Patients with Stroke: A Multidimensional Prospective Analysis"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5515-9172","authenticated-orcid":false,"given":"Emilio Rub\u00e9n","family":"Pego P\u00e9rez","sequence":"first","affiliation":[{"name":"Departament of Psychiatry, Radiology, Public Health, Nursing and Medicine, Faculty of Nursing, University of Santiago de Compostela, 15704 Santiago de Compostela, Spain"},{"name":"Research Group of Dependencie, Gerontology y Geriatrics, Faculty of Nursing, University of Santiago de Compostela, 15704 Santiago de Compostela, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes","family":"Bermello L\u00f3pez","sequence":"additional","affiliation":[{"name":"Neurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"G\u00f3mez Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Neurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7418-0457","authenticated-orcid":false,"given":"Mar\u00eda del Rosario","family":"Mar\u00edn Arn\u00e9s","sequence":"additional","affiliation":[{"name":"Neurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercedes","family":"Fern\u00e1ndez V\u00e1zquez","sequence":"additional","affiliation":[{"name":"Neurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlota","family":"Touza Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Galician Health Service, Santiago de Compostela Hospital, 15704 Santiago de Compostela, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Irene","family":"N\u00fa\u00f1ez Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Neurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,8]]},"reference":[{"key":"ref_1","unstructured":"Puente Castillo, E. 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