{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T09:15:38Z","timestamp":1765530938804,"version":"3.48.0"},"reference-count":35,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology International"],"abstract":"<jats:p>Background: Migraine is a highly prevalent neurological disorder and a leading cause of disability, particularly among working-age adults. Although the Work Productivity and Activity Impairment (WPAI) questionnaire is widely used to assess the functional impact of health conditions, no validated Arabic version specific to migraine is currently available. This study was conducted to validate the Arabic version of the WPAI:Migraine questionnaire among Arabic-speaking migraine patients in Saudi Arabia. Methods: A cross-sectional psychometric validation study was conducted at a tertiary headache clinic between June 2023 and January 2024. Adult patients diagnosed with episodic or chronic migraine, based on the International Classification of Headache Disorders, 3rd edition (ICHD-3), completed the Arabic version of the WPAI:Migraine and the validated Arabic version of the Migraine Disability Assessment Scale (MIDAS). Test\u2013retest reliability was assessed after two weeks. Psychometric properties, including reliability, criterion validity, and known-group validity, were evaluated using intraclass correlation coefficients (ICCs), Pearson\u2019s and Spearman\u2019s correlations, and one-way ANOVA. Results: Eighty-two patients completed the study (76.8% female; mean age 38 \u00b1 11 years). The Arabic WPAI:Migraine questionnaire demonstrated substantial-to-almost-perfect test\u2013retest reliability (ICC range: 0.68\u20130.84). WPAI:Migraine domain scores correlated significantly with MIDAS scores\u2014particularly for activity impairment (r = 0.576), presenteeism (r = 0.526), and absenteeism (r = 0.522)\u2014and increased consistently across MIDAS disability grades, supporting validity. Conclusions: The Arabic WPAI:Migraine questionnaire is a valid and reliable instrument for assessing work productivity and activity impairment among Arabic-speaking migraine patients, suitable for clinical and research use.<\/jats:p>","DOI":"10.3390\/neurolint17120202","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T08:30:17Z","timestamp":1765528217000},"page":"202","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychometric Validation of the Arabic Version of the WPAI:Migraine Questionnaire in Patients with Migraine"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9308-3033","authenticated-orcid":false,"given":"Abdulrazaq","family":"Albilali","sequence":"first","affiliation":[{"name":"Neurology Unit, Department of Medicine, College of Medicine, King Saud University, Riyadh 11472, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9474-3408","authenticated-orcid":false,"given":"Rema A.","family":"Almutawa","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Neuroscience Institute, King Fahad Medical City, Riyadh 11525, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6289-7629","authenticated-orcid":false,"given":"Elaf A.","family":"Almusahel","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Neuroscience Institute, King Fahad Medical City, Riyadh 11525, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6930-047X","authenticated-orcid":false,"given":"Renad A.","family":"Almutawa","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, King Fahad Medical City, Riyadh 11525, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0363-3767","authenticated-orcid":false,"given":"Nasser A.","family":"Almutawa","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Ad Diriyah Hospital, Riyadh 13717, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0418-8323","authenticated-orcid":false,"given":"Faisal M.","family":"Almutawa","sequence":"additional","affiliation":[{"name":"Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh 12713, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1973-6870","authenticated-orcid":false,"given":"Shiekha","family":"AlAujan","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8531-556X","authenticated-orcid":false,"given":"Haya M.","family":"AlMalag","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/S0140-6736(17)32154-2","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990\u20132016: A systematic analysis for the Global Burden of Disease Study 2016","volume":"390","author":"Vos","year":"2017","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s10194-018-0846-2","article-title":"Migraine is first cause of disability in under 50s: Will health politicians now take notice?","volume":"19","author":"Steiner","year":"2018","journal-title":"J. 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