{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:36:48Z","timestamp":1787315808735,"version":"build-2736575974"},"reference-count":50,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Loewenstein Rehabilitation Medical Center fund","award":["KM600010322"],"award-info":[{"award-number":["KM600010322"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurol. Int.","Neurology International"],"abstract":"<jats:p>Background\/Objectives: Patients with prolonged disorder of consciousness (PDOC) who regained consciousness in intensive care for consciousness rehabilitation (ICCR) were referred to further brain rehabilitation (FBR). The current retrospective cohort study evaluated the functional and cognitive outcomes of FBR. Methods: We assessed outcomes in 258 PDOC patients during FBR and used multivariate regression analyses to examine the influence of demographic and clinical characteristics on outcomes. Results: During FBR, Functional Independence Measure (FIM) motor, cognitive, and total scores improved from 21 \u00b1 11, 11 \u00b1 10, and 32 \u00b1 15 to 43 \u00b1 26, 18 \u00b1 7, and 61 \u00b1 32, respectively (p &lt; 0.001). Dynamic Lowenstein Occupational Therapy Cognitive Assessment (DLOTCA) total scores increased from 57 \u00b1 29 to 82 \u00b1 36, and the average 6-min-walk (6MW) distances improved from 295 to 374 m (p &lt; 0.001). Higher discharge FIM and DLOTCA scores were associated with younger age, traumatic etiology of the brain injury, shorter time to regaining consciousness, and higher FIM and DLOTCA scores at admission to FBR (p &lt; 0.05). Conclusions: We observed functional and cognitive improvement in the examined patients. The improvement was associated with factors that may mainly reflect the severity of brain damage. The findings support continuing rehabilitation before and after emerging from PDOC.<\/jats:p>","DOI":"10.3390\/neurolint18080158","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:37:34Z","timestamp":1787312254000},"page":"158","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rehabilitation Outcomes in Patients Who Regained Consciousness"],"prefix":"10.3390","volume":"18","author":[{"given":"Elena","family":"Aidinoff","sequence":"first","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"},{"name":"The Department of Rehabilitation, The School of Mathematics, Tel Aviv University, Tel Aviv 6139001, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almothana","family":"Khatib","sequence":"additional","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Oksamitni","sequence":"additional","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"},{"name":"The Department of Rehabilitation, The School of Mathematics, Tel Aviv University, Tel Aviv 6139001, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilana","family":"Gelernter","sequence":"additional","affiliation":[{"name":"The Department of Rehabilitation, The School of Mathematics, Tel Aviv University, Tel Aviv 6139001, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilach","family":"Front","sequence":"additional","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amiram","family":"Catz","sequence":"additional","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"},{"name":"The Department of Rehabilitation, The School of Mathematics, Tel Aviv University, Tel Aviv 6139001, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Shaklai","sequence":"additional","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"},{"name":"The Department of Rehabilitation, The School of Mathematics, Tel Aviv University, Tel Aviv 6139001, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Motin","sequence":"additional","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinne","family":"Serfaty","sequence":"additional","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"},{"name":"The Department of Rehabilitation, The School of Mathematics, Tel Aviv University, Tel Aviv 6139001, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Rubin-Asher","sequence":"additional","affiliation":[{"name":"The Intensive Care for Consciousness Rehabilitation Department, The Departments of Spinal Rehabilitation, Pediatric Rehabilitation, Stroke Rehabilitation, and Brain Injury Rehabilitation, Loewenstein Rehabilitation Medical Center, 278 Achuza St., POB 3, Raanana 4355840, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"ref_1","unstructured":"Royal College of Physicians (2020). 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