{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:24:40Z","timestamp":1760149480241,"version":"build-2065373602"},"reference-count":24,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Conacyt Fellowship 574809"},{"name":"Academic Group of Neurosciences UV-CA-28"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NeuroSci"],"abstract":"<jats:p>Autism in humans is a lifelong behavioral disorder that typically manifests in early infancy, primarily affecting boys. It arises from neurodevelopmental changes that significantly impact social behavior, with the cerebellum being one of the principal affected regions. In this study, we investigated the cerebellum in an autism animal model, recording the multiunit activity of cerebellar vermis lobules 6 and 7 (L6 and L7) in male rats with autism-like behavior induced by postnatal valproate treatment. Two groups were formed: control (Ctrl) and experimental (VPA) males, which were further divided based on their living conditions into standard (Std) or enriched environments (EE). Social arenas were used for recording purposes. Both groups and lobules showed increased multiunit amplitude during social interaction (SI) and vertical exploration (VE), with higher amplitudes observed in VPA males. Interestingly, the EE significantly reduced the amplitude during SI, suggesting that EE promotes neural plasticity, resulting in improved social responses with fewer activated neurons, meaning improved activity with less energy consumption. Consequently, EE proves to be a valuable strategy for addressing the challenges associated with autism behavior.<\/jats:p>","DOI":"10.3390\/neurosci4030016","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T07:58:52Z","timestamp":1690531132000},"page":"178-185","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multiunit Recording of Cerebellar Cortex in Autistic Male Rats during Social Interaction in Enriched Environments"],"prefix":"10.3390","volume":"4","author":[{"given":"Omar E.","family":"Cruz-Magos","sequence":"first","affiliation":[{"name":"Doctorado en Investigaciones Cerebrales, Universidad Veracruzana, Xalapa 91190, Veracruz, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grecia","family":"Herrera-Meza","sequence":"additional","affiliation":[{"name":"Benem\u00e9rita Escuela Normal Veracruzana \u201cEnr\u00edque C. 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