{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:30:17Z","timestamp":1781587817574,"version":"3.54.5"},"reference-count":31,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2018,3,22]],"date-time":"2018-03-22T00:00:00Z","timestamp":1521676800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education","award":["2017R1D1A1B03035355"],"award-info":[{"award-number":["2017R1D1A1B03035355"]}]},{"name":"the Korea Health Technology R&amp;D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health &amp; Welfare, Republic of Korea","award":["HI14C1062"],"award-info":[{"award-number":["HI14C1062"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Glaucoma is a leading cause of loss of sight. High intraocular pressure (IOP) is the most critical risk factor. However, glaucoma develops even within a normal IOP range. Normal tension glaucoma (NTG) is more common in Asia, whereas high tension glaucoma is more common in Western countries. The pathogenesis of glaucoma, especially NTG, is poorly understood. We evaluated the correlation between dietary nutrient intake and glaucoma using data from subjects \u226540 years old from the ongoing, nationwide, population-based study, the Korean National Health and Nutrition Examination Survey V (2008\u20132012). Dietary intake was determined using the 24 h recall method. Fiber (g\/day), ash (g\/day), calcium (mg\/day), phosphorus (mg\/day), iron (mg\/day), sodium (mg\/day), potassium (mg\/day), \u03b2-Carotene (\u03bcg\/day), retinol (\u03bcg\/day), vitamin A (\u03bcg Retinol Equivalents\/day), thiamine (mg\/day), riboflavin (mg\/day), niacin (mg\/day), and vitamin C (mg\/day) were included in nutrient intake data. All nutrient intake was divided into quartiles. The mean IOP did not differ according to quartiles from any nutrients (all p &gt; 0.05). After adjusting for age, gender, income status, education level, smoking, alcohol consumption, physical activity, diabetes, hypertension, IOP, and total energy, the intake of niacin was associated with glaucoma (p = 0.013). Among subjects with IOP \u2264 21 mmHg, only niacin was related to glaucoma in a multivariate analysis (p = 0.022). Dietary nutrient intake was associated with open-angle glaucoma independent of IOP. Individuals with NTG showed lower intake of niacin among nutrients. This finding suggests the possibility that proper diet counseling may be another modifiable factor, aside from IOP, particularly among patients with NTG.<\/jats:p>","DOI":"10.3390\/nu10040387","type":"journal-article","created":{"date-parts":[[2018,3,22]],"date-time":"2018-03-22T05:14:55Z","timestamp":1521695695000},"page":"387","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Dietary Niacin and Open-Angle Glaucoma: The Korean National Health and Nutrition Examination Survey"],"prefix":"10.3390","volume":"10","author":[{"given":"Kyoung","family":"Jung","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-ku, Seoul 137-701, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-ku, Seoul 137-701, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-ku, Seoul 137-701, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,3,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br. 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