{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T23:23:15Z","timestamp":1783466595273,"version":"3.55.0"},"reference-count":37,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2018,11,3]],"date-time":"2018-11-03T00:00:00Z","timestamp":1541203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Celiac disease may present with a range of different symptoms, including abdominal problems in a broader sense, iron deficiency and \u201cconstant tiredness\u201d. All of these symptoms should consequently lead the clinicians to consider celiac disease as a potential etiopathogenetic cause. Although the pathophysiology of celiac disease is well documented, the actual mechanisms for disease presentation(s) are less well understood. We here address the topic of fatigue in celiac disease. A systematic literature search identified 298 papers of which five met the criteria for full evaluation. None of the reviewed papers were of high quality and had several methodological weaknesses. We conclude that there is an unmet need to study the contributing factors and management of fatigue in celiac disease.<\/jats:p>","DOI":"10.3390\/nu10111652","type":"journal-article","created":{"date-parts":[[2018,11,5]],"date-time":"2018-11-05T10:43:45Z","timestamp":1541414625000},"page":"1652","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Fatigue as an Extra-Intestinal Manifestation of Celiac Disease: A Systematic Review"],"prefix":"10.3390","volume":"10","author":[{"given":"Lars-Petter","family":"Jelsness-J\u00f8rgensen","sequence":"first","affiliation":[{"name":"Department of Health Science, \u00d8stfold University College, N-1757 Halden, Norway"},{"name":"Department of Gastroenterology, \u00d8stfold Hospital Trust Kalnes, N-1714 Gr\u00e5lum, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomm","family":"Bernklev","sequence":"additional","affiliation":[{"name":"Department of Research and Innovation, Vestfold Hospital Trust, N-3103 T\u00f8nsberg, Norway"},{"name":"Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, N-0318 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1713-5545","authenticated-orcid":false,"given":"Knut E. A.","family":"Lundin","sequence":"additional","affiliation":[{"name":"K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, N-0318 Oslo, Norway"},{"name":"Department of gastroenterology, Oslo University Hospital Rikshospitalet, N-0372 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,11,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1136\/gutjnl-2011-301346","article-title":"The Oslo definitions for coeliac disease and related terms","volume":"62","author":"Ludvigsson","year":"2013","journal-title":"Gut"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1136\/gutjnl-2013-306578","article-title":"Diagnosis and management of adult coeliac disease: Guidelines from the British Society of Gastroenterology","volume":"63","author":"Ludvigsson","year":"2014","journal-title":"Gut"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/nrgastro.2015.131","article-title":"Extraintestinal manifestations of coeliac disease","volume":"12","author":"Leffler","year":"2015","journal-title":"Nat. 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