{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:49:34Z","timestamp":1788554974177,"version":"build-2803163510"},"reference-count":37,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>There is currently no standardized procedure to assess sarcopenia in long-stay catabolic patients. Our aim is to analyze a novel ultrasound muscle assessment protocol in these patients versus healthy controls, by carrying out a prospective observational study. We designed a new ultrasound protocol that assesses quadriceps rectus femoris (QRF) muscle quality in real-time B-mode, color-Doppler, and M-mode ultrasound, and evaluates QRF intramuscular central tendon thickness, cross-sectional area, and muscle thickness in ultrasound B-mode. Logistic regression was performed as a multivariable analysis on 29 cases and 19 controls. The QRF muscle area and thickness were shown to significantly decrease (p \u2264 0.001), and the central tendon thickness significantly increased (p = 0.047) in cases versus controls. The QRF muscle echogenicity and angiogenic activity fasciculations, subcutaneous edema, and intramuscular fluid were also significantly different between the two groups (p &lt; 0.001). The selected variables in the multivariate logit analysis were the muscle area (OR per cm2 = 0.07; 95% confidence interval (CI) = 0.012\u20130.41) and the central tendon thickness (OR per mm 1.887; 95% CI = 2.66\u201313.38).<\/jats:p>","DOI":"10.3390\/nu10121849","type":"journal-article","created":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T06:02:09Z","timestamp":1543816929000},"page":"1849","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Assessment of Muscle Wasting in Long-Stay ICU Patients Using a New Ultrasound Protocol"],"prefix":"10.3390","volume":"10","author":[{"given":"Carmen Rosa","family":"Hern\u00e1ndez-Socorro","sequence":"first","affiliation":[{"name":"Department of Radiology, Hospital Universitario de Gran Canaria Dr. Negr\u00edn, Universidad de Las Palmas de Gran Canaria, Barranco de la Ballena s\/n, 35010 Las Palmas de Gran Canaria, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Saavedra","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Universidad de Las Palmas de Gran Canaria, 35010 Las Palmas de Gran Canaria, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"L\u00f3pez-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital Universitario de Gran Canaria Dr. Negr\u00edn, Universidad of Las Palmas de Gran Canaria, Barranco de la Ballena s\/n, 35010 Las Palmas de Gran Canaria, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Ruiz-Santana","sequence":"additional","affiliation":[{"name":"Department of Intensive Care, Hospital Universitario de Gran Canaria Dr. Negr\u00edn, Universidad of Las Palmas de Gran Canaria, Barranco de la Ballena s\/n, 35010 Las Palmas de Gran Canaria, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Coelho-J\u00fanior, H.J., Rodrigues, B., Uchida, M., and Marzetti, E. 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