{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:21:58Z","timestamp":1790266918615,"version":"4.1.0"},"reference-count":38,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T00:00:00Z","timestamp":1543795200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: The organic food market has grown rapidly worldwide in the past 15 years. However, evidence concerning the health effects of organic foods is scarce. We evaluated the cross-sectional association of organic food purchase, as a proxy of organic food consumption, with diabetes in a nationally representative population. Methods: We included 8199 participants aged \u226520 years from the National Health and Nutrition Examination Survey 2007\u20132008 and 2009\u20132010. Organic food purchase and frequency were ascertained by questionnaires. Diabetes was defined as a self-reported physician diagnosis or a hemoglobin A1c level \u22656.5% or both. We used logistic regression with sample weights to estimate the odds ratios (ORs) and 95% confidence intervals (CIs). Results: Individuals who reported purchasing organic foods were less likely to have diabetes compared to those who did not report organic food purchase. After adjustment for age, gender, race\/ethnicity, family history of diabetes, socioeconomic status, and dietary and lifestyle factors, the OR of diabetes associated with organic food purchase was 0.80 (95% CI 0.68\u20130.93). The association remained significant after additional adjustment for BMI with OR of 0.80 (0.69\u20130.94). Conclusions: In a nationally representative population, frequent organic food purchase was inversely associated with diabetes prevalence in adults in the United States.<\/jats:p>","DOI":"10.3390\/nu10121877","type":"journal-article","created":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T06:02:09Z","timestamp":1543816929000},"page":"1877","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Inverse Association between Organic Food Purchase and Diabetes Mellitus in US Adults"],"prefix":"10.3390","volume":"10","author":[{"given":"Yangbo","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9553-8764","authenticated-orcid":false,"given":"Buyun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda G.","family":"Snetselaar","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA"},{"name":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank B.","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA"},{"name":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA 02115, USA"},{"name":"Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7301-5786","authenticated-orcid":false,"given":"Wei","family":"Bao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA"},{"name":"Obesity Research and Education Initiative, University of Iowa, Iowa City, IA 52242, USA"},{"name":"Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,12,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1001\/jama.2015.10029","article-title":"Prevalence of and trends in diabetes among adults in the united states, 1988\u20132012","volume":"314","author":"Menke","year":"2015","journal-title":"J. Am. Med. Assoc."},{"key":"ref_2","unstructured":"International Diabetes Federation (2015). IDF Diabetes Atlas, International Diabetes Federation. [7th ed.]."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.envint.2016.02.013","article-title":"Exposure to pesticides and diabetes: A systematic review and meta-analysis","volume":"91","author":"Evangelou","year":"2016","journal-title":"Environ. Int."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Hernandez-Alonso, P., Camacho-Barcia, L., Bullo, M., and Salas-Salvado, J. (2017). Nuts and dried fruits: An update of their beneficial effects on type 2 diabetes. Nutrients, 9.","DOI":"10.3390\/nu9070673"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1146\/annurev-publhealth-031816-044437","article-title":"Organic food in the diet: Exposure and health implications","volume":"38","author":"Brantsaeter","year":"2017","journal-title":"Annu. Rev. Public Health"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1080\/02652030110113799","article-title":"Pesticide residues in conventional, integrated pest management (ipm)-grown and organic foods: Insights from three us data sets","volume":"19","author":"Baker","year":"2002","journal-title":"Food Addit. Contam."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1017\/S0007114515005073","article-title":"Composition differences between organic and conventional meat: A systematic literature review and meta-analysis","volume":"115","author":"Baranski","year":"2016","journal-title":"Br. J. Nutr."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2774","DOI":"10.1002\/jsfa.5639","article-title":"Comparison of nutritional quality between conventional and organic dairy products: A meta-analysis","volume":"92","author":"Palupi","year":"2012","journal-title":"J. Sci. Food Agric."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"348","DOI":"10.7326\/0003-4819-157-5-201209040-00007","article-title":"Are organic foods safer or healthier than conventional alternatives?: A systematic review","volume":"157","author":"Brandeau","year":"2012","journal-title":"Ann. Intern. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1017\/S0007114515003761","article-title":"Health and dietary traits of organic food consumers: Results from the nutrinet-sante study","volume":"114","author":"Baudry","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.9734\/EJNFS\/2015\/12734","article-title":"Customers purchasing organic food\u2014Do they live healthier? Results of the german national nutrition survey ii","volume":"5","author":"Wittig","year":"2015","journal-title":"Eur. J. Nutr. Food Saf."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e1406","DOI":"10.1542\/peds.2012-2579","article-title":"Organic foods: Health and environmental advantages and disadvantages","volume":"130","author":"Forman","year":"2012","journal-title":"Pediatrics"},{"key":"ref_13","unstructured":"Greene, C. (2017). Organic Market Overview."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3945\/an.115.009258","article-title":"Update on nhanes dietary data: Focus on collection, release, analytical considerations, and uses to inform public policy","volume":"7","author":"Ahluwalia","year":"2016","journal-title":"Adv. Nutr."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1093\/pch\/20.2.89","article-title":"Food insecurity and hunger: A review of the effects on children\u2019s health and behaviour","volume":"20","author":"Ke","year":"2015","journal-title":"Paediatr. Child Health"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.2337\/dc09-1777","article-title":"International expert committee report on the role of the a1c assay in the diagnosis of diabetes","volume":"32","author":"Nathan","year":"2009","journal-title":"Diabetes Care"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"562","DOI":"10.2337\/dc09-1524","article-title":"Prevalence of diabetes and high risk for diabetes using a1c criteria in the US population in 1988\u20132006","volume":"33","author":"Cowie","year":"2010","journal-title":"Diabetes Care"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.amepre.2018.05.018","article-title":"Trends in the prevalence of diabetes among U.S. Adults: 1999\u20132016","volume":"55","author":"Fang","year":"2018","journal-title":"Am. J. Prev. Med."},{"key":"ref_19","first-page":"1","article-title":"National health and nutrition examination survey: Plan and operations, 1999\u20132010","volume":"56","author":"Zipf","year":"2013","journal-title":"Vital Health Stat."},{"key":"ref_20","unstructured":"Centers for Disease Control and Prevention (1996). Nhanes III Reference Manuals and Reports."},{"key":"ref_21","first-page":"1","article-title":"National health and nutrition examination survey: Analytic guidelines, 1999\u20132010","volume":"161","author":"Johnson","year":"2013","journal-title":"Vital Health Stat. 2."},{"key":"ref_22","unstructured":"Centers for Disease Control and Prevention, and National Center for Health Statistics (2018, November 27). Adult Tobacco Use Information_Glossary, Available online: https:\/\/www.cdc.gov\/nchs\/nhis\/tobacco\/tobacco_glossary.htm."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/aje\/kwv241","article-title":"Multiple healthful dietary patterns and type 2 diabetes in the women\u2019s health initiative","volume":"183","author":"Cespedes","year":"2016","journal-title":"Am. J. Epidemiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"399","DOI":"10.3945\/jn.113.183079","article-title":"The healthy eating index-2010 is a valid and reliable measure of diet quality according to the 2010 dietary guidelines for americans","volume":"144","author":"Guenther","year":"2014","journal-title":"J. Nutr."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1097\/EDE.0b013e31829ef01a","article-title":"The prevalence of type 1 diabetes in the united states","volume":"24","author":"Menke","year":"2013","journal-title":"Epidemiology"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1017\/S0007114517000058","article-title":"Prospective association between consumption frequency of organic food and body weight change, risk of overweight or obesity: Results from the nutrinet-sante study","volume":"117","author":"Baudry","year":"2017","journal-title":"Br. J. Nutr."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1038\/bjc.2014.148","article-title":"Organic food consumption and the incidence of cancer in a large prospective study of women in the united kingdom","volume":"110","author":"Bradbury","year":"2014","journal-title":"Br. J. Cancer"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1002\/jsfa.5614","article-title":"Health effects of an organic diet--consumer experiences in the netherlands","volume":"92","year":"2012","journal-title":"J. Sci. Food Agric."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Curl, C.L., Beresford, S.A., Hajat, A., Kaufman, J.D., Moore, K., Nettleton, J.A., and Diez-Roux, A.V. (2013). Associations of organic produce consumption with socioeconomic status and the local food environment: Multi-ethnic study of atherosclerosis (mesa). PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0069778"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/oemed-2013-101659","article-title":"Pesticide use and incident diabetes among wives of farmers in the agricultural health study","volume":"71","author":"Starling","year":"2014","journal-title":"Occup. Environ. Med."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1007\/s00394-017-1520-1","article-title":"Association between organic food consumption and metabolic syndrome: Cross-sectional results from the nutrinet-sante study","volume":"57","author":"Baudry","year":"2017","journal-title":"Eur. J. Nutr."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.taap.2013.01.025","article-title":"Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives","volume":"268","author":"Mostafalou","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"e316","DOI":"10.1016\/S2542-5196(17)30141-9","article-title":"Restricting the use of antibiotics in food-producing animals and its associations with antibiotic resistance in food-producing animals and human beings: A systematic review and meta-analysis","volume":"1","author":"Tang","year":"2017","journal-title":"Lancet Planet. Health"},{"key":"ref_34","unstructured":"Dangour, A., Aikenhead, A., Hayter, A., Allen, E., Lock, K., and Uauy, R. (2009). Comparison of Putative Health Effects of Organically and Conventionally Produced Foodstuffs: A Systematic Review, Nutrition and Public Health Intervention Research Unit London School of Hygiene & Tropical Medicine."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"3633","DOI":"10.1210\/jc.2015-2696","article-title":"Use of antibiotics and risk of type 2 diabetes: A population-based case-control study","volume":"100","author":"Mikkelsen","year":"2015","journal-title":"J. Clin. Endocr. Metab."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.plipres.2008.10.002","article-title":"Dietary fats and prevention of type 2 diabetes","volume":"48","author":"Riserus","year":"2009","journal-title":"Prog. Lipid Res."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"k1497","DOI":"10.1136\/bmj.k1497","article-title":"Prevalence of diagnosed type 1 and type 2 diabetes among us adults in 2016 and 2017: Population based study","volume":"362","author":"Xu","year":"2018","journal-title":"BMJ Br. Med. J."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1007\/s11606-014-3147-8","article-title":"National patterns in diabetes screening: Data from the national health and nutrition examination survey (nhanes) 2005\u20132012","volume":"30","author":"Kiefer","year":"2015","journal-title":"J. Gen. Intern. Med."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/10\/12\/1877\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T15:30:39Z","timestamp":1760196639000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/10\/12\/1877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,3]]},"references-count":38,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2018,12]]}},"alternative-id":["nu10121877"],"URL":"https:\/\/doi.org\/10.3390\/nu10121877","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,3]]}}}