{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T20:57:07Z","timestamp":1775854627487,"version":"3.50.1"},"reference-count":18,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T00:00:00Z","timestamp":1544486400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Research evaluating the relationship between lactose intolerance (LI) symptoms and age, gender and race is reviewed. An exhaustive search was conducted on the Google Scholar and PubMed databases. The evidence suggests that women, the elderly or specific racial groups are not more susceptible to LI, but rather dose, body size and genetic differences in lactase non-persistence (LNP) are the primary drivers of intolerance symptoms.<\/jats:p>","DOI":"10.3390\/nu10121956","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T03:27:49Z","timestamp":1544585269000},"page":"1956","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Gender, Age, Race and Lactose Intolerance: Is There Evidence to Support a Differential Symptom Response? A Scoping Review"],"prefix":"10.3390","volume":"10","author":[{"given":"Rebecca A","family":"Lapides","sequence":"first","affiliation":[{"name":"Nutrition Science, Purdue University, West Lafayette, IN 47906, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8872-6276","authenticated-orcid":false,"given":"Dennis A","family":"Savaiano","sequence":"additional","affiliation":[{"name":"Nutrition Science, Purdue University, West Lafayette, IN 47906, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,12,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/ajcn\/57.3.399","article-title":"Correlation of lactose maldigestion, lactose intolerance, and milk intolerance","volume":"57","author":"Johnson","year":"1993","journal-title":"Am. J. Clin. 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Gerontol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/ajcn\/33.1.17","article-title":"Comparative tolerance of adolescents of differing ethnic backgrounds to lactose-containing and lactose-free dairy drinks I. Initial experience with a double-blind procedure","volume":"33","author":"Haverberg","year":"1980","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/ajcn\/33.1.22","article-title":"Comparative tolerance of adolescents of differing ethnic backgrounds to lactose-containing and lactose-free dairy drinks. II. Improvement of a double-blind test","volume":"33","author":"Kwon","year":"1980","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1093\/ajcn\/45.6.1457","article-title":"Milk consumption, symptom response, and lactose digestion in milk intolerance","volume":"45","author":"Rosado","year":"1987","journal-title":"Am. 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Nutr."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/apt.12006","article-title":"Is the subjective perception of lactose intolerance influenced by the psychological profile?","volume":"36","author":"Tomba","year":"2012","journal-title":"Alimen. Pharmacol. Ther."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1186\/1475-2891-12-160","article-title":"Improving lactose digestion and symptoms of lactose intolerance with a novel galacto-oligosaccharide (RP-G28): A randomized, double-blind clinical trial","volume":"12","author":"Savaiano","year":"2013","journal-title":"Nutr. J."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/10\/12\/1956\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T15:33:00Z","timestamp":1760196780000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/10\/12\/1956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,11]]},"references-count":18,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2018,12]]}},"alternative-id":["nu10121956"],"URL":"https:\/\/doi.org\/10.3390\/nu10121956","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,11]]}}}