{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:47:25Z","timestamp":1762876045253,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T00:00:00Z","timestamp":1545436800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH Institute on Aging","award":["R01AG039374"],"award-info":[{"award-number":["R01AG039374"]}]},{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","award":["2617755","MRSG014-025-01-CNE"],"award-info":[{"award-number":["2617755","MRSG014-025-01-CNE"]}],"id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Osteoarthritis (OA) is a leading cause of immobility in the United States and is associated with older age, inflammation, and obesity. Prudent dietary patterns have been associated with disease prevention, yet little evidence exists describing diet quality (DQ) in older overweight or obese African American (AA) adults with OA and its relation to body composition. We conducted a secondary data analysis of a dataset containing alternate Healthy Eating Index-2010 (AHEI-2010), body composition, OA severity, and serum interleukin-6 (IL-6) data from 126 AA females (aged 60\u201387 years) with OA to examine the relationships between these variables. Our sample had poor DQ and reported having higher OA severity as measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Interleukin-6 was negatively correlated with AHEI-2010, and AHEI-2010 and the WOMAC physical function subcategory (WOMACpf) were significant predictors of IL-6 (odds ratio (OR): 0.95, 95% confidence interval (CI) 0.92\u20130.99 and 1.04, 95% CI 1.01\u20131.07, respectively, p &lt; 0.05) but not body composition. In conclusion, AHEI-2010 and WOMACpf were significant predictors of inflammation (IL-6) and AHEI-2010 accounted for ~16% of the variation of IL-6 (inflammation) in this sample.<\/jats:p>","DOI":"10.3390\/nu11010026","type":"journal-article","created":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T10:37:49Z","timestamp":1545647869000},"page":"26","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Associations between Alternate Healthy Eating Index-2010, Body Composition, Osteoarthritis Severity, and Interleukin-6 in Older Overweight and Obese African American Females with Self-Reported Osteoarthritis"],"prefix":"10.3390","volume":"11","author":[{"given":"Macy","family":"Mears","sequence":"first","affiliation":[{"name":"Department of Clinical Nutrition, College of Health Sciences, Rush University, Chicago, IL 60601, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Tussing-Humphreys","sequence":"additional","affiliation":[{"name":"Institute for Health Research and Policy, University of Illinois at Chicago, Chicago, IL 60601, USA"},{"name":"University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, IL 60601, USA"},{"name":"Department of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL 60601, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah","family":"Cerwinske","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition, College of Health Sciences, Rush University, Chicago, IL 60601, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2431-9687","authenticated-orcid":false,"given":"Christy","family":"Tangney","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition, College of Health Sciences, Rush University, Chicago, IL 60601, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Hughes","sequence":"additional","affiliation":[{"name":"Institute for Health Research and Policy, University of Illinois at Chicago, Chicago, IL 60601, USA"},{"name":"School of Public Health, University of Illinois at Chicago, Chicago, IL 60601, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Fitzgibbons","sequence":"additional","affiliation":[{"name":"Institute for Health Research and Policy, University of Illinois at Chicago, Chicago, IL 60601, USA"},{"name":"University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, IL 60601, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Gomez-Perez","sequence":"additional","affiliation":[{"name":"Department of Clinical Nutrition, College of Health Sciences, Rush University, Chicago, IL 60601, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,12,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/art.23176","article-title":"National Arthritis Data Workgroup. 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