{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:44:53Z","timestamp":1791978293977,"version":"4.4.0"},"reference-count":144,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T00:00:00Z","timestamp":1553212800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Vitamin A is a crucial micronutrient for pregnant women and their fetuses. In addition to being essential for morphological and functional development and for ocular integrity, vitamin A exerts systemic effects on several fetal organs and on the fetal skeleton. Vitamin A requirements during pregnancy are therefore greater. Vitamin A deficiency (VAD) remains the leading cause of preventable blindness in the world. VAD in pregnant women is a public health issue in most developing countries. In contrast, in some developed countries, excessive vitamin A intake during pregnancy can be a concern since, when in excess, this micronutrient may exert teratogenic effects in the first 60 days following conception. Routine prenatal vitamin A supplementation for the prevention of maternal and infant morbidity and mortality is not recommended; however, in regions where VAD is a public health issue, vitamin A supplementation is recommended to prevent night blindness. Given the importance of this topic and the lack of a complete, up-to-date review on vitamin A and pregnancy, an extensive review of the literature was conducted to identify conflicting or incomplete data on the topic as well as any gaps in existing data.<\/jats:p>","DOI":"10.3390\/nu11030681","type":"journal-article","created":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T06:56:52Z","timestamp":1553497012000},"page":"681","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":205,"title":["Vitamin A and Pregnancy: A Narrative Review"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4974-5073","authenticated-orcid":false,"given":"Sabina","family":"Bastos Maia","sequence":"first","affiliation":[{"name":"Maternal and Child Healthcare Postgraduate Program, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 50070-550, Pernambuco, Brazil"},{"name":"Department of Obstetrics and Gynecology, Lauro Wanderley University Hospital, Federal University of Para\u00edba (UFPB), Jo\u00e3o Pessoa 58059-900, Para\u00edba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7039-2052","authenticated-orcid":false,"given":"Alex Sandro","family":"Rolland Souza","sequence":"additional","affiliation":[{"name":"Maternal and Child Healthcare Postgraduate Program, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 50070-550, Pernambuco, Brazil"},{"name":"Department of Maternal and Child Healthcare, Federal University of Pernambuco (UFPE), Recife 50670-901, Pernambuco, Brazil"},{"name":"Biological and Health Sciences Center, Catholic University of Pernambuco (UNICAP), Recife 50050-900, Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0653-5324","authenticated-orcid":false,"given":"Maria de F\u00e1tima","family":"Costa Caminha","sequence":"additional","affiliation":[{"name":"Maternal and Child Healthcare Postgraduate Program, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 50070-550, Pernambuco, Brazil"},{"name":"Coordination of the Nursing Mentoring Program, Faculdade Pernambucana de Sa\u00fade (FPS), Recife 51180-001, Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzana","family":"Lins da Silva","sequence":"additional","affiliation":[{"name":"Maternal and Child Healthcare Postgraduate Program, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 50070-550, Pernambuco, Brazil"},{"name":"Coordination of the Nursing Mentoring Program, Faculdade Pernambucana de Sa\u00fade (FPS), Recife 51180-001, Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel de S\u00e1 Barreto Luna","family":"Callou Cruz","sequence":"additional","affiliation":[{"name":"Department of Nursing, Regional University of Cariri (URCA), Crato 63105-000, Cear\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Carvalho dos Santos","sequence":"additional","affiliation":[{"name":"Research Directorate, IMIP, Recife 50070-550, Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malaquias","family":"Batista Filho","sequence":"additional","affiliation":[{"name":"Maternal and Child Healthcare Postgraduate Program, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 50070-550, Pernambuco, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,3,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0021-9258(18)88553-2","article-title":"The necessity of certain lipins in the diet during growth","volume":"15","author":"McCollum","year":"1913","journal-title":"J. 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