{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T01:51:34Z","timestamp":1772761894791,"version":"3.50.1"},"reference-count":31,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T00:00:00Z","timestamp":1555718400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Celiac disease (CD) is an immunologically-mediated disorder characterized by duodenal mucosa villi atrophy. Iron absorption is usually reduced in celiac patients making every kind of oral iron treatment unhelpful because of malasorption. Feralgine\u2122 is a new product that has been demonstrated to be more bioavailable. As such, the aim of our study was to evaluate the absorption of Feralgine\u2122 in adult patients with CD. Methods: Twenty-six adults affected by Iron Deficiency Anemia (IDA), of which 14 were also affected by CD and 12 were not affected by CD, were enrolled. An oral iron absorption test (OIAT) was performed in each patient by administrating Feralgine\u2122, and serum iron was evaluated at baseline (T0) and after 2 h (T1) from the oral iron ingestion. Results: The OIAT was well tolerated in all patients, and, surprisingly, an equivalent statistically significant improvement in serum iron occurred in the two groups of patients (IDA plus CD: T0 = 28.21 \u00b5g\/dL vs. T1 = 94.14 \u00b5g\/dL p = 0.004 and IDA without CD: T0 = 34.91 \u00b5g\/dL vs. T1 = 118.83 \u00b5g\/dL, p = 0.0003). Conclusions: These results demonstrated the high absorption of Feralgine\u2122 in celiac patients, confirming our previous data obtained with Ferrous Bysglicinate in children with CD.<\/jats:p>","DOI":"10.3390\/nu11040887","type":"journal-article","created":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T11:02:53Z","timestamp":1555930973000},"page":"887","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Feralgine\u2122 a New Approach for Iron Deficiency Anemia in Celiac Patients"],"prefix":"10.3390","volume":"11","author":[{"given":"Laura","family":"Giancotti","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Talarico","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe Antonio","family":"Mazza","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santina","family":"Marrazzo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Gangemi","sequence":"additional","affiliation":[{"name":"Clinical Chemistry Laboratory, Pugliese-Ciaccio Hospital, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Miniero","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pugliese-Ciaccio Hospital-Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1469-7825","authenticated-orcid":false,"given":"Marco","family":"Bertini","sequence":"additional","affiliation":[{"name":"R&amp;D Department, Laboratori Baldacci SpA, 56124 Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,4,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0140-6736(17)31796-8","article-title":"Coeliac disease","volume":"391","author":"Lebwohl","year":"2018","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"4644","DOI":"10.3748\/wjg.15.4644","article-title":"A short review of malabsorption and anemia","volume":"15","author":"Gisbert","year":"2009","journal-title":"World J. 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