{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:44:12Z","timestamp":1791927852680,"version":"4.3.4"},"reference-count":179,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T00:00:00Z","timestamp":1559606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010198","name":"Ministerio de Econom\u00eda, Industria y Competitividad, Gobierno de Espa\u00f1a","doi-asserted-by":"publisher","award":["PI16\/01298"],"award-info":[{"award-number":["PI16\/01298"]}],"id":[{"id":"10.13039\/501100010198","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Traditional dietary recommendations to renal patients limited the intake of fruits and vegetables because of their high potassium content. However, this paradigm is rapidly changing due to the multiple benefits derived from a fundamentally vegetarian diet such as, improvement in gut dysbiosis, reducing the number of pathobionts and protein-fermenting species leading to a decreased production of the most harmful uremic toxins, while the high fiber content of these diets enhances intestinal motility and short-chain fatty acid production. Metabolic acidosis in chronic kidney disease (CKD) is aggravated by the high consumption of meat and refined cereals, increasing the dietary acid load, while the intake of fruit and vegetables is able to neutralize the acidosis and its deleterious consequences. Phosphorus absorption and bioavailability is also lower in a vegetarian diet, reducing hyperphosphatemia, a known cause of cardiovascular mortality in CKD. The richness of multiple plants in magnesium and vitamin K avoids their deficiency, which is common in these patients. These beneficial effects, together with the reduction of inflammation and oxidative stress observed with these diets, may explain the reduction in renal patients\u2019 complications and mortality, and may slow CKD progression. Finally, although hyperkalemia is the main concern of these diets, the use of adequate cooking techniques can minimize the amount absorbed.<\/jats:p>","DOI":"10.3390\/nu11061263","type":"journal-article","created":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T04:26:40Z","timestamp":1559622400000},"page":"1263","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":110,"title":["Vegetable-Based Diets for Chronic Kidney Disease? It Is Time to Reconsider"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6962-8184","authenticated-orcid":false,"given":"Aleix","family":"Cases","sequence":"first","affiliation":[{"name":"Medicine Department, Universitat de Barcelona, Institut d\u2019Investigacions Biom\u00e8qiques August Pi i Sunyer, 08036 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Secundino","family":"Cigarr\u00e1n-Guldr\u00eds","sequence":"additional","affiliation":[{"name":"Servicio de Nefrolog\u00eda, Hospital da Costa, 27880 Burela, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6604-3327","authenticated-orcid":false,"given":"Sebasti\u00e1n","family":"Mas","sequence":"additional","affiliation":[{"name":"Servicio de Nefrolog\u00eda, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, 28040 Madrid, Spain"},{"name":"Centro de investigaci\u00f3n en Red de Diabetes y Enfermedades Metab\u00f3licas Asociadas (CIBERDEM), 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio","family":"Gonzalez-Parra","sequence":"additional","affiliation":[{"name":"Servicio de Nefrolog\u00eda, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, 28040 Madrid, Spain"},{"name":"Red de Investigaci\u00f3n Renal (RedinRen), 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,6,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1093\/ije\/dyy030","article-title":"Patterns of plant and animal protein intake are strongly associated with cardiovascular mortality: The Adventist Health Study-2 cohort","volume":"47","author":"Tharrey","year":"2018","journal-title":"Int. J. Epidemiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"597","DOI":"10.3945\/ajcn.112.044073","article-title":"Risk of hospitalization or death from ischemic heart disease among British vegetarians and nonvegetarians: Results from the EPIC-Oxford cohort study","volume":"97","author":"Crowe","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1093\/jn\/82.1.88","article-title":"The amino acids composition and nutritive value of proteins. V. Amino acid requirements as pattern for protein evaluation","volume":"82","author":"Ramarao","year":"1964","journal-title":"J. Nutr."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1079\/PHN2005730","article-title":"Height, age at menarche, body weight and body mass index in life-long vegetarians","volume":"8","author":"Rosell","year":"2005","journal-title":"Public Health Nutr."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1159\/000189341","article-title":"A low-nitrogen low-phosphorus Vegan diet for patients with chronic renal failure","volume":"74","author":"Barsotti","year":"1996","journal-title":"Nephron"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/ckj\/sfu125","article-title":"Low-protein diets in CKD: How can we achieve them? A narrative, pragmatic review","volume":"8","author":"Piccoli","year":"2015","journal-title":"Clin. Kidney J."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Piccoli, G.B., Capizzi, I., Vigotti, F.N., Leone, F., D\u2019Alessandro, C., Giuffrida, D., Nazha, M., Roggero, S., Colombi, N., and Mauro, G. (2016). Low protein diets in patients with chronic kidney disease: A bridge between mainstream and complementary-alternative medicines?. BMC Nephrol., 17.","DOI":"10.1186\/s12882-016-0275-x"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/hdi.12414","article-title":"Reduced protein bound uraemic toxins in vegetarian kidney failure patients treated by haemodiafiltration","volume":"20","author":"Kandouz","year":"2016","journal-title":"Hemodial. Int."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/ki.1989.12","article-title":"Control of serum potassium during fasting in patients with end-stage renal disease","volume":"35","author":"Gifford","year":"1989","journal-title":"Kidney Int."},{"key":"ref_10","first-page":"9","article-title":"Gut microbiota in chronic kidney disease","volume":"37","year":"2017","journal-title":"Nefrologia"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1038\/ki.2012.345","article-title":"Chronic kidney disease alters intestinal microbial flora","volume":"83","author":"Vaziri","year":"2013","journal-title":"Kidney Int."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"745","DOI":"10.2215\/CJN.00600207","article-title":"A randomized, controlled trial of lactic acid bacteria for idiopathic hyperoxaluria","volume":"2","author":"Goldfarb","year":"2007","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.numecd.2015.03.015","article-title":"Dietary protein-fiber ratio associates with circulating levels of indoxyl sulfate and p-cresyl sulfate in chronic kidney disease patients","volume":"25","author":"Rossi","year":"2015","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1053\/j.jrn.2012.04.002","article-title":"Foods with added fiber lower serum creatinine levels in patients with chronic kidney disease","volume":"23","author":"Salmean","year":"2013","journal-title":"J. Ren. Nutr."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1194\/jlr.R036012","article-title":"The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism","volume":"54","author":"Groen","year":"2013","journal-title":"J. Lipid Res."},{"key":"ref_16","first-page":"185","article-title":"Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health","volume":"7","author":"Margolles","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.2217\/fmb-2017-0059","article-title":"Short-chain fatty acids: A link between prebiotics and microbiota in chronic kidney disease","volume":"12","author":"Esgalhado","year":"2017","journal-title":"Future Microbiol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Marzocco, S., Fazeli, G., Di Micco, L., Autore, G., Adesso, S., Dal Piaz, F., Heidland, A., and Di Iorio, B. (2018). Supplementation of Short-Chain Fatty Acid, Sodium Propionate, in Patients on Maintenance Hemodialysis: Beneficial Effects on Inflammatory Parameters and Gut-Derived Uremic Toxins, A Pilot Study (PLAN Study). J. Clin. Med., 7.","DOI":"10.3390\/jcm7100315"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12986-019-0343-x","article-title":"Effects of fermentable high fiber diet supplementation on gut derived and conventional nitrogenous product in patients on maintenance hemodialysis: A randomized controlled trial","volume":"16","author":"Khosroshahi","year":"2019","journal-title":"Nutr. Metab. (Lond)."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1053\/j.jrn.2016.02.005","article-title":"Nutrient Non-equivalence: Does Restricting High-Potassium Plant Foods Help to Prevent Hyperkalemia in Hemodialysis Patients?","volume":"26","author":"Goldfarb","year":"2016","journal-title":"J. Ren. Nutr."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1681\/ASN.2016060656","article-title":"Constipation and Incident CKD","volume":"28","author":"Sumida","year":"2017","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1007\/s10482-016-0737-y","article-title":"A reduction in the butyrate producing species Roseburia spp. and Faecalibacterium prausnitzii is associated with chronic kidney disease progression","volume":"109","author":"Jiang","year":"2016","journal-title":"Antonie Van Leeuwenhoek"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1159\/000493862","article-title":"Gut Microbial Product Predicts Cardiovascular Risk in Chronic Kidney Disease Patients","volume":"48","author":"Jadoon","year":"2018","journal-title":"Am. J. Nephrol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/mnfr.201100542","article-title":"Relevance of protein fermentation to gut health","volume":"56","author":"Windey","year":"2012","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/ejcn.2011.141","article-title":"A vegan or vegetarian diet substantially alters the human colonic faecal microbiota","volume":"66","author":"Zimmer","year":"2012","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"F857","DOI":"10.1152\/ajprenal.00513.2015","article-title":"Resistant starch alters gut microbiome and metabolomic profiles concurrent with amelioration of chronic kidney disease in rats","volume":"310","author":"Kieffer","year":"2016","journal-title":"Am. J. Physiol. Physiol."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Laffin, M.R., Tayebi Khosroshahi, H., Park, H., Laffin, L.J., Madsen, K., Kafil, H.S., Abedi, B., Shiralizadeh, S., and Vaziri, N.D. (2019). Amylose resistant starch (HAM-RS2) supplementation increases the proportion of Faecalibacterium bacteria in end-stage renal disease patients: Microbial analysis from a randomized placebo-controlled trial. Hemodial. Int., hdi.12753.","DOI":"10.1111\/hdi.12753"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/hdi.12653","article-title":"Effect of high amylose resistant starch (HAM-RS2) supplementation on biomarkers of inflammation and oxidative stress in hemodialysis patients: A randomized clinical trial","volume":"22","author":"Vaziri","year":"2018","journal-title":"Hemodial. Int."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Zybailov, B.L., Glazko, G.V., Rahmatallah, Y., Andreyev, D.S., McElroy, T., Karaduta, O., Byrum, S.D., Orr, L., Tackett, A.J., and Mackintosh, S.G. (2019). Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats. PLoS One, 14.","DOI":"10.1371\/journal.pone.0199274"},{"key":"ref_30","unstructured":"(2000). Clinical practice guidelines for nutrition in chronic renal failure. K\/DOQI, National Kidney Foundation. Am. J. Kidney Dis., 35, S1\u2013S140."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1093\/ajh\/hpt133","article-title":"Plasma Bicarbonate and Odds of Incident Hypertension","volume":"26","author":"Mandel","year":"2013","journal-title":"Am. J. Hypertens."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1053\/j.ajkd.2013.01.017","article-title":"Association of Serum Bicarbonate With Risk of Renal and Cardiovascular Outcomes in CKD: A Report From the Chronic Renal Insufficiency Cohort (CRIC) Study","volume":"62","author":"Dobre","year":"2013","journal-title":"Am. J. Kidney Dis."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1053\/j.ajkd.2015.08.028","article-title":"Metabolic Acidosis of CKD: An Update","volume":"67","author":"Kraut","year":"2016","journal-title":"Am. J. Kidney Dis."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.2215\/CJN.03730411","article-title":"Serum Bicarbonate and Mortality in Stage 3 and Stage 4 Chronic Kidney Disease","volume":"6","author":"Navaneethan","year":"2011","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1681\/ASN.2008111205","article-title":"Bicarbonate supplementation slows progression of CKD and improves nutritional status","volume":"20","author":"Varagunam","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.clnu.2011.03.008","article-title":"Diet-induced metabolic acidosis","volume":"30","author":"Adeva","year":"2011","journal-title":"Clin. Nutr."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/ajcn\/68.3.576","article-title":"Estimation of net endogenous noncarbonic acid production in humans from diet potassium and protein contents","volume":"68","author":"Frassetto","year":"1998","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/ki.2011.331","article-title":"The key to halting progression of CKD might be in the produce market, not in the pharmacy","volume":"81","author":"Uribarri","year":"2012","journal-title":"Kidney Int."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1093\/ndt\/17.8.1419","article-title":"Elevations of serum phosphorus and potassium in mild to moderate chronic renal insufficiency","volume":"17","author":"Hsu","year":"2002","journal-title":"Nephrol. Dial. Transplant"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2215\/CJN.02430312","article-title":"A Comparison of Treating Metabolic Acidosis in CKD Stage 4 Hypertensive Kidney Disease with Fruits and Vegetables or Sodium Bicarbonate","volume":"8","author":"Goraya","year":"2013","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/ki.2011.313","article-title":"Dietary acid reduction with fruits and vegetables or bicarbonate attenuates kidney injury in patients with a moderately reduced glomerular filtration rate due to hypertensive nephropathy","volume":"81","author":"Goraya","year":"2012","journal-title":"Kidney Int."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1053\/j.jrn.2013.08.004","article-title":"Vegetarianism: Advantages and drawbacks in patients with chronic kidney diseases","volume":"23","author":"Chauveau","year":"2013","journal-title":"J. Ren. Nutr."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1001\/jama.2009.96","article-title":"Effect of food additives on hyperphosphatemia among patients with end-stage renal disease: A randomized controlled trial","volume":"301","author":"Sullivan","year":"2009","journal-title":"JAMA"},{"key":"ref_44","first-page":"1","article-title":"Phosphorus and Nutrition in Chronic Kidney Disease","volume":"2012","author":"Egido","year":"2012","journal-title":"Int. J. Nephrol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2215\/CJN.11051210","article-title":"Source Matters: From Phosphorus Load to Bioavailability","volume":"6","author":"Fukagawa","year":"2011","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2215\/CJN.05040610","article-title":"Vegetarian Compared with Meat Dietary Protein Source and Phosphorus Homeostasis in Chronic Kidney Disease","volume":"6","author":"Moe","year":"2011","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1056\/NEJMoa0706130","article-title":"Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis","volume":"359","author":"Mannstadt","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.2215\/CJN.08200718","article-title":"Gut-Derived Metabolites and Chronic Kidney Disease","volume":"13","author":"Vanholder","year":"2018","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1042\/CS20171107","article-title":"Altered microbiome in chronic kidney disease: Systemic effects of gut-derived uremic toxins","volume":"132","author":"Lau","year":"2018","journal-title":"Clin. Sci. (Lond)."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1681\/ASN.2013101062","article-title":"The uremic toxicity of indoxyl sulfate and p-cresyl sulfate: A systematic review","volume":"25","author":"Vanholder","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1161\/CIRCRESAHA.116.305360","article-title":"Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease","volume":"116","author":"Tang","year":"2015","journal-title":"Circ. Res."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1159\/000360010","article-title":"Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD","volume":"39","author":"Wong","year":"2014","journal-title":"Am. J. Nephrol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1042\/CS20160203","article-title":"Urea, a true uremic toxin: The empire strikes back","volume":"131","author":"Lau","year":"2017","journal-title":"Clin. Sci. (Lond)."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Koguchi, T., and Tadokoro, T. (2019). Beneficial Effect of Dietary Fiber on Hyperuricemia in Rats and Humans: A Review. Int. J. Vitam. Nutr. Res., 1\u201320.","DOI":"10.1024\/0300-9831\/a000548"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/sdi.12348","article-title":"Dietary restrictions in dialysis patients: Is there anything left to eat?","volume":"28","author":"Tortorici","year":"2015","journal-title":"Semin. Dial."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"982","DOI":"10.2215\/CJN.12491211","article-title":"The production of p-cresol sulfate and indoxyl sulfate in vegetarians versus omnivores","volume":"7","author":"Patel","year":"2012","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1159\/000346628","article-title":"Very low protein diet reduces indoxyl sulfate levels in chronic kidney disease","volume":"35","author":"Marzocco","year":"2013","journal-title":"Blood Purif."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1111\/j.1440-1797.2011.01464.x","article-title":"Nutritional status of vegetarians on maintenance haemodialysis","volume":"16","author":"Wu","year":"2011","journal-title":"Nephrology (Carlton)."},{"key":"ref_59","first-page":"159","article-title":"Treatment of chronic renal failure with dietary fiber","volume":"21","author":"Rampton","year":"1984","journal-title":"Clin. Nephrol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/ejcn.2014.237","article-title":"Dietary fiber effects in chronic kidney disease: A systematic review and meta-analysis of controlled feeding trials","volume":"69","author":"Chiavaroli","year":"2015","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1053\/j.jrn.2014.09.002","article-title":"Fiber supplementation lowers plasma p-cresol in chronic kidney disease patients","volume":"25","author":"Salmean","year":"2015","journal-title":"J. Ren. Nutr."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.2215\/CJN.00490114","article-title":"Effect of increasing dietary fiber on plasma levels of colon-derived solutes in hemodialysis patients","volume":"9","author":"Sirich","year":"2014","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_63","unstructured":"Wu, M., Cai, X., Lin, J., Zhang, X., Scott, E.M., and Li, X. (2018). Association between fibre intake and indoxyl sulphate\/P-cresyl sulphate in patients with chronic kidney disease: Meta-analysis and systematic review of experimental studies. Clin. Nutr."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1093\/ajcn\/63.5.766","article-title":"Resistant starch lowers fecal concentrations of ammonia and phenols in humans","volume":"63","author":"Birkett","year":"1996","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1017\/BJN20061936","article-title":"The influence of inulin on the absorption of nitrogen and the production of metabolites of protein fermentation in the colon","volume":"96","author":"Geboes","year":"2006","journal-title":"Br. J. Nutr."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1053\/j.jrn.2005.10.007","article-title":"Fermentable Carbohydrate Supplementation Alters Nitrogen Excretion in Chronic Renal Failure","volume":"16","author":"Younes","year":"2006","journal-title":"J. Ren. Nutr."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/eurheartj\/ehy799","article-title":"Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women","volume":"40","author":"Wang","year":"2019","journal-title":"Eur. Heart J."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1172\/JCI94601","article-title":"l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans","volume":"129","author":"Koeth","year":"2019","journal-title":"J. Clin. Invest."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"e02210","DOI":"10.1128\/mBio.02210-15","article-title":"Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota","volume":"7","author":"Chen","year":"2016","journal-title":"MBio"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"i3","DOI":"10.1093\/ndtplus\/sfr163","article-title":"Magnesium basics","volume":"5","author":"Ketteler","year":"2012","journal-title":"Clin. Kidney J."},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"Hughes, J., Chiu, D.Y.Y., Kalra, P.A., and Green, D. (2018). Prevalence and outcomes of proton pump inhibitor associated hypomagnesemia in chronic kidney disease. PLoS One, 13.","DOI":"10.1371\/journal.pone.0197400"},{"key":"ref_72","unstructured":"Oka, T., Hamano, T., Sakaguchi, Y., Yamaguchi, S., Kubota, K., Senda, M., Yonemoto, S., Shimada, K., Matsumoto, A., and Hashimoto, N. (2018). Proteinuria-associated renal magnesium wasting leads to hypomagnesemia: A common electrolyte abnormality in chronic kidney disease. Nephrol. Dial. Transplant."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/j.kint.2017.04.011","article-title":"Dietary magnesium supplementation prevents and reverses vascular and soft tissue calcifications in uremic rats","volume":"92","author":"Raya","year":"2017","journal-title":"Kidney Int."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1038\/s41598-018-20241-3","article-title":"Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation","volume":"8","author":"Tinnemans","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/nrneph.2015.74","article-title":"Magnesium and cardiovascular complications of chronic kidney disease","volume":"11","author":"Massy","year":"2015","journal-title":"Nat. Rev. Nephrol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1042\/CS20110506","article-title":"Endothelial cells and magnesium: Implications in atherosclerosis","volume":"122","author":"Maier","year":"2012","journal-title":"Clin. Sci."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/ki.2013.327","article-title":"Hypomagnesemia is a significant predictor of cardiovascular and non-cardiovascular mortality in patients undergoing hemodialysis","volume":"85","author":"Sakaguchi","year":"2014","journal-title":"Kidney Int."},{"key":"ref_78","first-page":"90","article-title":"Serum magnesium concentration is a significant predictor of mortality in peritoneal dialysis patients","volume":"30","author":"Fein","year":"2014","journal-title":"Adv. Perit. Dial."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1159\/000341868","article-title":"Relationship between Serum Magnesium Levels and Cardiovascular Events in Chronic Kidney Disease Patients","volume":"36","author":"Kanbay","year":"2012","journal-title":"Am. J. Nephrol."},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Xiong, J., He, T., Wang, M., Nie, L., Zhang, Y., Wang, Y., Huang, Y., Feng, B., Zhang, J., and Zhao, J. (2019). Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: A systematic review and meta-analysis. J. Nephrol.","DOI":"10.1007\/s40620-019-00601-6"},{"key":"ref_81","doi-asserted-by":"crossref","unstructured":"Sakaguchi, Y., Fujii, N., Shoji, T., Hayashi, T., Rakugi, H., Iseki, K., Tsubakihara, Y., and Isaka, Y. (2014). Committee of Renal Data Registry of the Japanese Society for Dialysis Therapy Magnesium modifies the cardiovascular mortality risk associated with hyperphosphatemia in patients undergoing hemodialysis: A cohort study. PLoS One, 9.","DOI":"10.1371\/journal.pone.0116273"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1038\/ki.2014.331","article-title":"Results from the Atherosclerosis Risk in Communities study suggest that low serum magnesium is associated with incident kidney disease","volume":"87","author":"Tin","year":"2015","journal-title":"Kidney Int."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.amjmed.2013.02.036","article-title":"Hypomagnesemia and the risk of death and GFR decline in chronic kidney disease","volume":"126","author":"Nagler","year":"2013","journal-title":"Am. J. Med."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1007\/s11255-008-9410-3","article-title":"Magnesium supplementation helps to improve carotid intima media thickness in patients on hemodialysis","volume":"40","author":"Turgut","year":"2008","journal-title":"Int. Urol. Nephrol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1007\/s11255-014-0751-9","article-title":"Magnesium retards the progress of the arterial calcifications in hemodialysis patients: A pilot study","volume":"46","author":"Tzanakis","year":"2014","journal-title":"Int. Urol. Nephrol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.ekir.2016.12.008","article-title":"Oral Magnesium Supplementation in Chronic Kidney Disease Stages 3 and 4: Efficacy, Safety, and Effect on Serum Calcification Propensity-A Prospective Randomized Double-Blinded Placebo-Controlled Clinical Trial","volume":"2","author":"Bressendorff","year":"2017","journal-title":"Kidney Int. reports"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000451070","article-title":"Vitamin K Deficiency in Chronic Kidney Disease: Evidence Is Building Up","volume":"45","author":"Fusaro","year":"2017","journal-title":"Am. J. Nephrol."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.clnu.2016.04.024","article-title":"Low vitamin K1 intake in haemodialysis patients","volume":"36","author":"Fusaro","year":"2017","journal-title":"Clin. Nutr."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/ki.2012.191","article-title":"Vitamin K intake and status are low in hemodialysis patients","volume":"82","author":"Cranenburg","year":"2012","journal-title":"Kidney Int."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"590","DOI":"10.2215\/CJN.06420909","article-title":"Vitamins K and D status in stages 3-5 chronic kidney disease","volume":"5","author":"Holden","year":"2010","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_91","doi-asserted-by":"crossref","unstructured":"Cupisti, A., D\u2019Alessandro, C., Gesualdo, L., Cosola, C., Gallieni, M., Egidi, M.F., and Fusaro, M. (2017). Non-Traditional Aspects of Renal Diets: Focus on Fiber, Alkali and Vitamin K1 Intake. Nutrients, 9.","DOI":"10.3390\/nu9050444"},{"key":"ref_92","doi-asserted-by":"crossref","unstructured":"Caluw\u00e9, R., Verbeke, F., and De Vriese, A.S. (2018). Evaluation of vitamin K status and rationale for vitamin K supplementation in dialysis patients. Nephrol. Dial. Transplant.","DOI":"10.1093\/ndt\/gfy373"},{"key":"ref_93","doi-asserted-by":"crossref","unstructured":"Cozzolino, M., Mangano, M., Galassi, A., Ciceri, P., Messa, P., and Nigwekar, S. (2019). Vitamin K in Chronic Kidney Disease. Nutrients, 11.","DOI":"10.3390\/nu11010168"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/eci.12718","article-title":"Does statins promote vascular calcification in chronic kidney disease?","volume":"47","author":"Chen","year":"2017","journal-title":"Eur. J. Clin. Invest."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1093\/ndt\/gfu224","article-title":"The impact of warfarin on the rate of progression of aortic stiffness in hemodialysis patients: A longitudinal study","volume":"29","author":"Poulin","year":"2014","journal-title":"Nephrol. Dial. Transplant"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1681\/ASN.2010040339","article-title":"Circulating nonphosphorylated carboxylated matrix gla protein predicts survival in ESRD","volume":"22","author":"Schlieper","year":"2011","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1002\/jbmr.3608","article-title":"Poor Vitamin K Status Is Associated With Low Bone Mineral Density and Increased Fracture Risk in End-Stage Renal Disease","volume":"34","author":"Evenepoel","year":"2019","journal-title":"J. Bone Miner. Res."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"631","DOI":"10.20452\/pamw.3041","article-title":"Effect of vitamin K2 on progression of atherosclerosis and vascular calcification in nondialyzed patients with chronic kidney disease stages 3-5","volume":"125","author":"Kurnatowska","year":"2015","journal-title":"Pol. Arch. Med. Wewn."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"3999","DOI":"10.1158\/1078-0432.CCR-16-0495","article-title":"Molecular Pathways: Cachexia Signaling\u2014A Targeted Approach to Cancer Treatment","volume":"22","author":"Miyamoto","year":"2016","journal-title":"Clin. Cancer Res."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000381990","article-title":"The Gut as a Source of Inflammation in Chronic Kidney Disease","volume":"130","author":"Lau","year":"2015","journal-title":"Nephron"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"399","DOI":"10.2217\/fmb.13.165","article-title":"Role of altered intestinal microbiota in systemic inflammation and cardiovascular disease in chronic kidney disease","volume":"9","author":"Mafra","year":"2014","journal-title":"Future Microbiol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.3945\/jn.109.114025","article-title":"A new dietary inflammatory index predicts interval changes in serum high-sensitivity C-reactive protein","volume":"139","author":"Cavicchia","year":"2009","journal-title":"J. Nutr."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"F90","DOI":"10.1152\/ajprenal.00358.2003","article-title":"Downregulation of hepatic acyl-CoA:diglycerol acyltransferase in chronic renal failure","volume":"287","author":"Vaziri","year":"2004","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"ref_104","first-page":"598","article-title":"Dietary fiber intake is associated with chronic kidney disease (CKD) progression and cardiovascular risk, but not protein nutritional status, in adults with CKD","volume":"26","author":"Lu","year":"2017","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/ki.2011.355","article-title":"High dietary fiber intake is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease","volume":"81","author":"Krishnamurthy","year":"2012","journal-title":"Kidney Int."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1017\/S1368980017001768","article-title":"Association of vegetarian diet with inflammatory biomarkers: A systematic review and meta-analysis of observational studies","volume":"20","author":"Haghighatdoost","year":"2017","journal-title":"Public Health Nutr."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.molmet.2016.05.011","article-title":"How gut microbes talk to organs: The role of endocrine and nervous routes","volume":"5","author":"Cani","year":"2016","journal-title":"Mol. Metab."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1525-139X.2009.00590.x","article-title":"The Role of Oxidative Stress in Chronic Kidney Disease","volume":"22","author":"Massy","year":"2009","journal-title":"Semin. Dial."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"155","DOI":"10.4162\/nrp.2012.6.2.155","article-title":"Long-term vegetarians have low oxidative stress, body fat, and cholesterol levels","volume":"6","author":"Kim","year":"2012","journal-title":"Nutr. Res. Pract."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1159\/000495540","article-title":"Antioxidant and Anti-Inflammatory Strategies Based on the Potentiation of Glutathione Peroxidase Activity Prevent Endothelial Dysfunction in Chronic Kidney Disease","volume":"51","author":"Vera","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"key":"ref_111","doi-asserted-by":"crossref","unstructured":"de Vries, J., Birkett, A., Hulshof, T., Verbeke, K., and Gibes, K. (2016). Effects of Cereal, Fruit and Vegetable Fibers on Human Fecal Weight and Transit Time: A Comprehensive Review of Intervention Trials. Nutrients, 8.","DOI":"10.3390\/nu8030130"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"50","DOI":"10.5740\/jaoacint.SGE_Macfarlane","article-title":"Bacteria, colonic fermentation, and gastrointestinal health","volume":"95","author":"Macfarlane","year":"2012","journal-title":"J. AOAC Int."},{"key":"ref_113","unstructured":"(2019, May 30). Scientific Opinion on Dietary Reference Values for Carbohydrates and Dietary Fibre. Available online: http:\/\/www.efsa.europa.eu\/sites\/default\/files\/scientific_output\/files\/main_documents\/1462.pdf."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1136\/gut.39.2.299","article-title":"Variability of gastrointestinal transit in healthy women and men","volume":"39","author":"Degen","year":"1996","journal-title":"Gut"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1089\/jmf.2005.8.281","article-title":"Flavonols, Flavones, Flavanones, and Human Health: Epidemiological Evidence","volume":"8","author":"Graf","year":"2005","journal-title":"J. Med. Food"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"508","DOI":"10.3109\/03602532.2014.978080","article-title":"Bioavailability of anthocyanins","volume":"46","author":"Fang","year":"2014","journal-title":"Drug Metab. Rev."},{"key":"ref_117","doi-asserted-by":"crossref","unstructured":"Saha, S., Nordstrom, J., Gerdtham, U.-G., Mattisson, I., Nilsson, P.M., and Scarborough, P. (2019). Prevention of Cardiovascular Disease and Cancer Mortality by Achieving Healthy Dietary Goals for the Swedish Population: A Macro-Simulation Modelling Study. Int. J. Environ. Res. Public Health, 16.","DOI":"10.3390\/ijerph16050890"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1038\/sj.ejcn.1602635","article-title":"Effect of the main dietary antioxidants (carotenoids, \u03b3-tocopherol, polyphenols and vitamin C) on \u03b1-tocopherol absorption","volume":"61","author":"Reboul","year":"2007","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1039\/c3fo60212e","article-title":"Citrus flavanones enhance carotenoid uptake by intestinal Caco-2 cells","volume":"4","author":"Claudie","year":"2013","journal-title":"Food Funct."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1080\/10408398.2016.1254595","article-title":"Interactions between phytochemicals from fruits and vegetables: Effects on bioactivities and bioavailability","volume":"58","author":"Phan","year":"2018","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.2215\/CJN.01150112","article-title":"Prevalence and factors associated with hyperkalemia in predialysis patients followed in a low-clearance clinic","volume":"7","author":"Sarafidis","year":"2012","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"141","DOI":"10.2215\/CJN.08960718","article-title":"Plant-Based Diets in CKD","volume":"14","author":"Clegg","year":"2019","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1038\/ki.2014.83","article-title":"Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate","volume":"86","author":"Goraya","year":"2014","journal-title":"Kidney Int."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1053\/j.jrn.2018.06.006","article-title":"Adequacy of Plant-Based Proteins in Chronic Kidney Disease","volume":"29","author":"Joshi","year":"2019","journal-title":"J. Ren. Nutr."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1093\/ndt\/gfx085","article-title":"Mediterranean diet as the diet of choice for patients with chronic kidney disease","volume":"33","author":"Chauveau","year":"2018","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"272","DOI":"10.2215\/CJN.06190616","article-title":"Healthy Dietary Patterns and Risk of Mortality and ESRD in CKD: A Meta-Analysis of Cohort Studies","volume":"12","author":"Kelly","year":"2017","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1681\/ASN.2018010008","article-title":"The Association of Mediterranean and DASH Diets with Mortality in Adults on Hemodialysis: The DIET-HD Multinational Cohort Study","volume":"29","author":"Saglimbene","year":"2018","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1093\/ajcn\/48.3.795","article-title":"Low blood pressure in vegetarians: Effects of specific foods and nutrients","volume":"48","author":"Sacks","year":"1988","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"1607S","DOI":"10.3945\/ajcn.2009.26736K","article-title":"Vegetarian diets: What do we know of their effects on common chronic diseases?","volume":"89","author":"Fraser","year":"2009","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1056\/NEJMoa1014296","article-title":"Changes in Diet and Lifestyle and Long-Term Weight Gain in Women and Men","volume":"364","author":"Mozaffarian","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.jand.2014.11.016","article-title":"A Systematic Review and Meta-Analysis of Changes in Body Weight in Clinical Trials of Vegetarian Diets","volume":"115","author":"Barnard","year":"2015","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/ndt\/gfy164","article-title":"Vegetarian diets and chronic kidney disease","volume":"34","author":"Chauveau","year":"2019","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/sj.ejcn.1601783","article-title":"Insulin sensitivity in Chinese ovo-lactovegetarians compared with omnivores","volume":"58","author":"Kuo","year":"2004","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"791","DOI":"10.2337\/dc08-1886","article-title":"Type of Vegetarian Diet, Body Weight, and Prevalence of Type 2 Diabetes","volume":"32","author":"Tonstad","year":"2009","journal-title":"Diabetes Care"},{"key":"ref_135","first-page":"373","article-title":"Vegetarian diets and glycemic control in diabetes: A systematic review and meta-analysis","volume":"4","author":"Yokoyama","year":"2014","journal-title":"Cardiovasc. Diagn. Ther."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.2337\/diacare.18.9.1233","article-title":"Renal, metabolic, and hormonal responses to proteins of different origin in normotensive, nonproteinuric type I diabetic patients","volume":"18","author":"Kontessis","year":"1995","journal-title":"Diabetes Care"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.1056\/NEJMoa1800389","article-title":"Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts","volume":"378","author":"Estruch","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"F830","DOI":"10.1152\/ajprenal.00587.2010","article-title":"Acid retention accompanies reduced GFR in humans and increases plasma levels of endothelin and aldosterone","volume":"300","author":"Wesson","year":"2011","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/MNH.0000000000000386","article-title":"Retarding progression of chronic kidney disease: Use of modalities that counter acid retention","volume":"27","author":"Kraut","year":"2018","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/ki.2012.82","article-title":"Net endogenous acid production is associated with a faster decline in GFR in African Americans","volume":"82","author":"Scialla","year":"2012","journal-title":"Kidney Int."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1053\/j.ackd.2012.11.001","article-title":"Dietary Acid Load: A Novel Nutritional Target in Chronic Kidney Disease?","volume":"20","author":"Scialla","year":"2013","journal-title":"Adv. Chronic Kidney Dis."},{"key":"ref_142","first-page":"239","article-title":"Increased endothelin activity mediates augmented distal nephron acidification induced by dietary protein","volume":"116","author":"Khanna","year":"2005","journal-title":"Trans. Am. Clin. Climatol. Assoc."},{"key":"ref_143","doi-asserted-by":"crossref","unstructured":"Barton, M., and Kohan, D. (2011). Endothelins and Kidney Acidification. Endothelin in Renal Physiology and Disease, Karger Publishers.","DOI":"10.1159\/isbn.978-3-8055-9795-1"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1053\/j.jrn.2017.12.008","article-title":"Dietary Potential Renal Acid Load and Risk of Albuminuria and Reduced Kidney Function in the Jackson Heart Study","volume":"28","author":"Banerjee","year":"2018","journal-title":"J. Ren. Nutr."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1053\/j.ajkd.2010.09.027","article-title":"Association of dietary patterns with albuminuria and kidney function decline in older white women: A subgroup analysis from the Nurses\u2019 Health Study","volume":"57","author":"Lin","year":"2011","journal-title":"Am. J. Kidney Dis."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1001\/jamapediatrics.2015.0411","article-title":"Longitudinal Effects of Dietary Sodium and Potassium on Blood Pressure in Adolescent Girls","volume":"169","author":"Buendia","year":"2015","journal-title":"JAMA Pediatr."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.nut.2008.04.005","article-title":"Association between dietary fiber and markers of systemic inflammation in the Women\u2019s Health Initiative Observational Study","volume":"24","author":"Ma","year":"2008","journal-title":"Nutrition"},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MNH.0b013e32834d54ca","article-title":"Nitric oxide synthase derangements and hypertension in kidney disease","volume":"21","author":"Baylis","year":"2012","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"937","DOI":"10.3109\/0886022X.2016.1165118","article-title":"Consumption of nitrate containing vegetables and the risk of chronic kidney disease: Tehran Lipid and Glucose Study","volume":"38","author":"Mirmiran","year":"2016","journal-title":"Ren. Fail."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1079\/NRR200485","article-title":"Organic anions and potassium salts in nutrition and metabolism","volume":"17","author":"Sabboh","year":"2004","journal-title":"Nutr. Res. Rev."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1681\/ASN.2013080905","article-title":"The Gut Microbiome, Kidney Disease, and Targeted Interventions","volume":"25","author":"Ramezani","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/j.1525-139X.2007.00303.x","article-title":"Phosphate metabolism in the setting of chronic kidney disease: Significance and recommendations for treatment","volume":"20","author":"Kestenbaum","year":"2007","journal-title":"Semin. Dial."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/ki.2015.284","article-title":"Relationship of dietary phosphate intake with risk of end-stage renal disease and mortality in chronic kidney disease stages 3-5: The Modification of Diet in Renal Disease Study","volume":"89","author":"Selamet","year":"2016","journal-title":"Kidney Int."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"13701","DOI":"10.1038\/s41598-018-32065-2","article-title":"Increased Phosphaturia Accelerates The Decline in Renal Function: A Search for Mechanisms","volume":"8","author":"Robles","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"ii224","DOI":"10.1093\/ndt\/gfw273","article-title":"The association between Dietary Approaches to Stop Hypertension and incidence of chronic kidney disease in adults: The Tehran Lipid and Glucose Study","volume":"32","author":"Asghari","year":"2017","journal-title":"Nephrol. Dial. Transplant"},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1017\/S0007114517003671","article-title":"Dietary fibre intake in relation to the risk of incident chronic kidney disease","volume":"119","author":"Mirmiran","year":"2018","journal-title":"Br. J. Nutr."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1001\/jamainternmed.2013.6473","article-title":"Vegetarian Dietary Patterns and Mortality in Adventist Health Study 2","volume":"173","author":"Orlich","year":"2013","journal-title":"JAMA Intern. Med."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1001\/jamainternmed.2016.4182","article-title":"Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality","volume":"176","author":"Song","year":"2016","journal-title":"JAMA Intern. Med."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.2215\/CJN.00810110","article-title":"Serum Phosphate and Mortality in Patients with Chronic Kidney Disease","volume":"5","author":"Eddington","year":"2010","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.2215\/CJN.09250912","article-title":"Effects of Dietary Phosphate Restriction and Phosphate Binders on FGF23 Levels in CKD","volume":"8","author":"Isakova","year":"2013","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1053\/j.ajkd.2015.10.018","article-title":"The Associations of Plant Protein Intake with All-Cause Mortality in CKD","volume":"67","author":"Chen","year":"2016","journal-title":"Am. J. Kidney Dis."},{"key":"ref_162","first-page":"1055","article-title":"Nutrient intake and risk of subtypes of esophageal and gastric cancer","volume":"10","author":"Mayne","year":"2001","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.3945\/ajcn.2010.29626","article-title":"Dietary protein and risk of ischemic heart disease in middle-aged men","volume":"92","author":"Preis","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.arcmed.2006.01.007","article-title":"Vegetable protein and fiber from cereal are inversely associated with the risk of hypertension in a Spanish cohort","volume":"37","author":"Alonso","year":"2006","journal-title":"Arch. Med. Res."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1093\/ajcn\/87.2.339","article-title":"Low-carbohydrate-diet score and risk of type 2 diabetes in women","volume":"87","author":"Halton","year":"2008","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1053\/j.ackd.2017.06.006","article-title":"Management of the Metabolic Acidosis of Chronic Kidney Disease","volume":"24","author":"Goraya","year":"2017","journal-title":"Adv. Chronic Kidney Dis."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.2215\/CJN.00150111","article-title":"Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease","volume":"6","author":"Scialla","year":"2011","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/ki.2010.388","article-title":"Higher serum bicarbonate levels within the normal range are associated with better survival and renal outcomes in African Americans","volume":"79","author":"Raphael","year":"2011","journal-title":"Kidney Int."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3945\/ajcn.2010.29673","article-title":"Accruing evidence on benefits of adherence to the Mediterranean diet on health: An updated systematic review and meta-analysis","volume":"92","author":"Sofi","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1159\/000371498","article-title":"The effect of a diet containing 70% protein from plants on mineral metabolism and musculoskeletal health in chronic kidney disease","volume":"40","author":"Moorthi","year":"2014","journal-title":"Am. J. Nephrol."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"3065S","DOI":"10.1093\/jn\/131.11.3065S","article-title":"The Mediterranean diets: What is so special about the diet of Greece? The scientific evidence","volume":"131","author":"Simopoulos","year":"2001","journal-title":"J. Nutr."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1753-4887.2009.00189.x","article-title":"Health benefits of dietary fiber","volume":"67","author":"Anderson","year":"2009","journal-title":"Nutr. Rev."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.numecd.2016.02.016","article-title":"Excess protein intake relative to fiber and cardiovascular events in elderly men with chronic kidney disease","volume":"26","author":"Xu","year":"2016","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1093\/ndt\/gfu287","article-title":"Alterations of intestinal barrier and microbiota in chronic kidney disease","volume":"30","author":"Sabatino","year":"2015","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Frassetto, L., Banerjee, T., Powe, N., and Sebastian, A. (2018). Acid Balance, Dietary Acid Load, and Bone Effects-A Controversial Subject. Nutrients, 10.","DOI":"10.3390\/nu10040517"},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"H80","DOI":"10.1111\/j.1750-3841.2008.00782.x","article-title":"The effects of boiling and leaching on the content of potassium and other minerals in potatoes","volume":"73","author":"Bethke","year":"2008","journal-title":"J. Food Sci."},{"key":"ref_177","unstructured":"Acal, I., Cigarran, S., Sanjurjo, A., Latorre, J., Men\u00e9ndez, N., Rodriguez, B., and Vazquez-Oderiz, L.R.A. (2019). Influence of culinary techniques of different vegetables products. Implications for chronic kidney disease patients. J. Renal Nutr., (under review)."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"943","DOI":"10.3945\/ajcn.2009.27521","article-title":"V Effect of vegetarian diets on bone mineral density: A Bayesian meta-analysis","volume":"90","author":"Nguyen","year":"2009","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"1627S","DOI":"10.3945\/ajcn.2009.26736N","article-title":"Health effects of vegan diets","volume":"89","author":"Craig","year":"2009","journal-title":"Am. J. Clin. Nutr."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/11\/6\/1263\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T12:55:55Z","timestamp":1760187355000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/11\/6\/1263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,4]]},"references-count":179,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,6]]}},"alternative-id":["nu11061263"],"URL":"https:\/\/doi.org\/10.3390\/nu11061263","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,4]]}}}