{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:06:50Z","timestamp":1788397610047,"version":"build-2803163510"},"reference-count":266,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2019,7,5]],"date-time":"2019-07-05T00:00:00Z","timestamp":1562284800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>This review discusses the personalised dietary approach with respect to inflammatory bowel disease (IBD). It identifies gene\u2013nutrient interactions associated with the nutritional deficiencies that people with IBD commonly experience, and the role of the Western diet in influencing these. It also discusses food intolerances and how particular genotypes can affect these. It is well established that with respect to food there is no \u201cone size fits all\u201d diet for those with IBD. Gene\u2013nutrient interactions may help explain this variability in response to food that is associated with IBD. Nutrigenomic research, which examines the effects of food and its constituents on gene expression, shows that\u2014like a number of pharmaceutical products\u2014food can have beneficial effects or have adverse (side) effects depending on a person\u2019s genotype. Pharmacogenetic research is identifying gene variants with adverse reactions to drugs, and this is modifying clinical practice and allowing individualised treatment. Nutrigenomic research could enable individualised treatment in persons with IBD and enable more accurate tailoring of food intake, to avoid exacerbating malnutrition and to counter some of the adverse effects of the Western diet. It may also help to establish the dietary pattern that is most protective against IBD.<\/jats:p>","DOI":"10.3390\/nu11071532","type":"journal-article","created":{"date-parts":[[2019,7,5]],"date-time":"2019-07-05T11:44:16Z","timestamp":1562327056000},"page":"1532","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["A Personalised Dietary Approach\u2014A Way Forward to Manage Nutrient Deficiency, Effects of the Western Diet, and Food Intolerances in Inflammatory Bowel Disease"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3064-1717","authenticated-orcid":false,"given":"Bobbi B","family":"Laing","sequence":"first","affiliation":[{"name":"Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand"},{"name":"Nutrition Society of New Zealand, Palmerston North 4444, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anecita Gigi","family":"Lim","sequence":"additional","affiliation":[{"name":"Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0107-4741","authenticated-orcid":false,"given":"Lynnette R","family":"Ferguson","sequence":"additional","affiliation":[{"name":"Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,7,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.cell.2015.11.001","article-title":"Personalized nutrition by prediction of glycemic responses","volume":"163","author":"Zeevi","year":"2015","journal-title":"Cell"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3754","DOI":"10.1021\/acs.jafc.8b00456","article-title":"Food design to feed the human gut microbiota","volume":"66","author":"Ercolini","year":"2018","journal-title":"J. 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