{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:11:59Z","timestamp":1792642319920,"version":"4.5.0"},"reference-count":245,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T00:00:00Z","timestamp":1579564800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1137750"],"award-info":[{"award-number":["OPP1137750"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Micronutrient deficiencies continue to be widespread among children under-five in low- and middle-income countries (LMICs), despite the fact that several effective strategies now exist to prevent them. This kind of malnutrition can have several immediate and long-term consequences, including stunted growth, a higher risk of acquiring infections, and poor development outcomes, all of which may lead to a child not achieving his or her full potential. This review systematically synthesizes the available evidence on the strategies used to prevent micronutrient malnutrition among children under-five in LMICs, including single and multiple micronutrient (MMN) supplementation, lipid-based nutrient supplementation (LNS), targeted and large-scale fortification, and point-of-use-fortification with micronutrient powders (MNPs). We searched relevant databases and grey literature, retrieving 35,924 papers. After application of eligibility criteria, we included 197 unique studies. Of note, we examined the efficacy and effectiveness of interventions. We found that certain outcomes, such as anemia, responded to several intervention types. The risk of anemia was reduced with iron alone, iron-folic acid, MMN supplementation, MNPs, targeted fortification, and large-scale fortification. Stunting and underweight, however, were improved only among children who were provided with LNS, though MMN supplementation also slightly increased length-for-age z-scores. Vitamin A supplementation likely reduced all-cause mortality, while zinc supplementation decreased the incidence of diarrhea. Importantly, many effects of LNS and MNPs held when pooling data from effectiveness studies. Taken together, this evidence further supports the importance of these strategies for reducing the burden of micronutrient malnutrition in children. Population and context should be considered when selecting one or more appropriate interventions for programming.<\/jats:p>","DOI":"10.3390\/nu12020289","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T11:25:59Z","timestamp":1579605959000},"page":"289","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":245,"title":["Micronutrient Supplementation and Fortification Interventions on Health and Development Outcomes among Children Under-Five in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"12","author":[{"given":"Emily","family":"Tam","sequence":"first","affiliation":[{"name":"Centre for Global Child Health, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1354-7086","authenticated-orcid":false,"given":"Emily C.","family":"Keats","sequence":"additional","affiliation":[{"name":"Centre for Global Child Health, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad","family":"Rind","sequence":"additional","affiliation":[{"name":"Centre of Excellence in Women and Child\u2019s Health, Aga Khan University, Karachi 74800, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jai K.","family":"Das","sequence":"additional","affiliation":[{"name":"Division of Women and Child Health, Aga Khan University, Karachi 74800, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulfiqar A.","family":"Bhutta","sequence":"additional","affiliation":[{"name":"Centre for Global Child Health, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada"},{"name":"Centre of Excellence in Women and Child\u2019s Health, Aga Khan University, Karachi 74800, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,1,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000371618","article-title":"The epidemiology of global micronutrient deficiencies","volume":"66","author":"Bailey","year":"2015","journal-title":"Ann. Nutr. Metab."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1016\/S2214-109X(13)70001-9","article-title":"Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995\u20132011: A systematic analysis of population-representative data","volume":"1","author":"Stevens","year":"2013","journal-title":"Lancet Glob. Health"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e528","DOI":"10.1016\/S2214-109X(15)00039-X","article-title":"Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: A pooled analysis of population-based surveys","volume":"3","author":"Stevens","year":"2015","journal-title":"Lancet Glob. Health"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"744","DOI":"10.3945\/jn.111.149393","article-title":"Global iodine status in 2011 and trends over the past decade","volume":"142","author":"Andersson","year":"2012","journal-title":"J. Nutr."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Wessells, K.R., and Brown, K.H. (2012). Estimating the global prevalence of zinc deficiency: Results based on zinc availability in national food supplies and the prevalence of stunting. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0050568"},{"key":"ref_6","unstructured":"World Health Organization (2017). Nutritional Anaemias: Tools for Effective Prevention and Control, World Health Organization."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"S560","DOI":"10.1177\/15648265070284S409","article-title":"Iron deficiency and child development","volume":"28","author":"Lozoff","year":"2007","journal-title":"Food Nutr. Bull."},{"key":"ref_8","first-page":"S160","article-title":"Vitamin and mineral deficiencies technical situation analysis: A report for the Ten Year Strategy for the Reduction of Vitamin and Mineral Deficiencies","volume":"28","author":"Sanghvi","year":"2007","journal-title":"Food Nutr. Bull."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0140-6736(07)61690-0","article-title":"Maternal and Child Undernutrition Study Group. Maternal and child undernutrition: Global and regional exposures and health consequences","volume":"371","author":"Black","year":"2008","journal-title":"Lancet"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1001\/jama.2010.1861","article-title":"Prenatal micronutrient supplementation and intellectual and motor function in early school-aged children in Nepal","volume":"304","author":"Christian","year":"2010","journal-title":"JAMA"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/S0140-6736(11)60555-2","article-title":"Inequality in early childhood: Risk and protective factors for early child development","volume":"378","author":"Walker","year":"2011","journal-title":"Lancet"},{"key":"ref_12","first-page":"CD008524","article-title":"Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age","volume":"3","author":"Imdad","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_13","first-page":"CD009384","article-title":"Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years of age","volume":"15","author":"Junior","year":"2014","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1177\/15648265090301S103","article-title":"Preventive zinc supplementation among infants, preschoolers, and older prepubertal children","volume":"30","author":"Brown","year":"2009","journal-title":"Food Nutr. Bull."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S0140-6736(13)60937-X","article-title":"Maternal and child undernutrition and overweight in low-income and middle-income countries","volume":"382","author":"Black","year":"2013","journal-title":"Lancet"},{"key":"ref_16","unstructured":"World Health Organization (2006). Guidelines on Food Fortification with Micronutrients, World Health Organization."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"402B","DOI":"10.2471\/BLT.10.083758","article-title":"Maternal multiple micronutrient supplementation and pregnancy outcomes in developing countries: Meta-analysis and meta-regression","volume":"89","author":"Kawai","year":"2011","journal-title":"Bull. World Health Organ."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Dewey, K.G., and Arimond, M. (2012). Lipid-based nutrient supplements: How can they combat child malnutrition?. PLoS Med., 9.","DOI":"10.1371\/journal.pmed.1001314"},{"key":"ref_19","unstructured":"Home Fortification Technical Advisory Group (2016). Home Fortification with Micronutrient Powders Sight and Life, Home Fortification Technical Advisory Group."},{"key":"ref_20","first-page":"CD009085","article-title":"Intermittent iron supplementation for improving nutrition and development in children under 12 years of age","volume":"7","author":"Jefferds","year":"2011","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1079\/PHN2004677","article-title":"Effect of iron supplementation on mental and motor development in children: Systematic review of randomised controlled trials","volume":"8","author":"Sachdev","year":"2005","journal-title":"Public Health Nutr."},{"key":"ref_22","first-page":"CD007991","article-title":"Zinc supplementation for mental and motor development in children","volume":"12","author":"Gogia","year":"2012","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_23","first-page":"CD008824","article-title":"Vitamin D supplementation for preventing infections in children under five years of age","volume":"11","author":"Yakoob","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.3945\/jn.107.086199","article-title":"Provision of multiple rather than two or fewer micronutrients more effectively improves growth and other outcomes in micronutrient-deficient children and adults","volume":"139","author":"Allen","year":"2009","journal-title":"J. Nutr."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3945\/ajcn.2008.26862","article-title":"Effects of micronutrients on growth of children under 5 y of age: Meta-analyses of single and multiple nutrient interventions","volume":"89","author":"Ramakrishnan","year":"2009","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_26","first-page":"CD009666","article-title":"Point-of-use fortification of foods with micronutrient powders containing iron in children of preschool and school-age","volume":"11","author":"Jefferds","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_27","first-page":"CD008959","article-title":"Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age","volume":"7","author":"Suchdev","year":"2011","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Salam, R.A., MacPhail, C., Das, J.K., and Bhutta, Z.A. (2013). Effectiveness of Micronutrient Powders (MNP) in women and children. BMC Public Health, 13.","DOI":"10.1186\/1471-2458-13-S3-S22"},{"key":"ref_29","first-page":"CD012611","article-title":"Preventive lipid-based nutrient supplements given with complementary foods to infants and young children 6 to 23 months of age for health, nutrition, and developmental outcomes","volume":"5","author":"Das","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/ajcn\/nqz262","article-title":"Lipid-based nutrient supplements and all-cause mortality in children 6-24 months of age: A meta-analysis of randomized controlled trials","volume":"111","author":"Stewart","year":"2019","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Eichler, K., Wieser, S., Ruthemann, I., and Brugger, U. (2012). Effects of micronutrient fortified milk and cereal food for infants and children: A systematic review. BMC Public Health, 12.","DOI":"10.1186\/1471-2458-12-506"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.3945\/jn.111.146845","article-title":"Do multiple micronutrient interventions improve child health, growth, and development?","volume":"141","author":"Ramakrishnan","year":"2011","journal-title":"J. Nutr."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/2046-4053-2-67","article-title":"Micronutrient fortification of food and its impact on woman and child health: A systematic review","volume":"2","author":"Das","year":"2013","journal-title":"Syst. Rev."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/ajcn\/nqz023","article-title":"Improved micronutrient status and health outcomes in low- and middle-income countries following large-scale fortification: Evidence from a systematic review and meta-analysis","volume":"109","author":"Keats","year":"2019","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1017\/S1368980016003189","article-title":"Effect of fortified milk on growth and nutritional status in young children: A systematic review and meta-analysis","volume":"20","author":"Matsuyama","year":"2017","journal-title":"Public Health Nutr."},{"key":"ref_36","first-page":"1","article-title":"Protocol: Efficacy and effectiveness of micronutrient supplementation and fortification interventions on the health and nutritional status of children under-five in low and middle-income countries","volume":"14","author":"Keats","year":"2018","journal-title":"Campbell Syst. Rev."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"key":"ref_38","unstructured":"Cochrane Effective Practice Organisation of Care (EPOC) (2017). Suggested risk of bias criteria for EPOC reviews. EPOC Resources for Review Authors, EPOC."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"ref_40","first-page":"136","article-title":"Effect of fortification of maize with cowpea and iron on growth and anaemia status of children","volume":"4","author":"Adom","year":"2010","journal-title":"Afr. J. Food Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ajcn\/86.2.412","article-title":"Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: Effects on growth and motor development","volume":"86","author":"Lartey","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"797","DOI":"10.3945\/ajcn.116.134692","article-title":"Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: A randomized controlled trial","volume":"104","author":"Lartey","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_43","first-page":"823","article-title":"Effect of consumption of micronutrient fortified candies on the iron and vitamin A status of children aged 3-6 years in rural Haryana","volume":"44","author":"Anand","year":"2007","journal-title":"Indian Pediatr."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"(1998). Randomised trial to assess benefits and safety of vitamin A supplementation linked to immunisation in early infancy. WHO\/CHD Immunisation-Linked Vitamin A Supplementation Study Group. Lancet, 352, 1257\u20131263.","DOI":"10.1016\/S0140-6736(98)02487-8"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.3945\/jn.114.207225","article-title":"Supplementation of Maternal Diets during Pregnancy and for 6 Months Postpartum and Infant Diets Thereafter with Small-Quantity Lipid-Based Nutrient Supplements Does Not Promote Child Growth by 18 Months of Age in Rural Malawi: A Randomized Controlled Trial","volume":"145","author":"Ashorn","year":"2015","journal-title":"J. Nutr."},{"key":"ref_46","first-page":"473","article-title":"Dual fortification of salt with iron and iodine in women and children in rural Ghana","volume":"84","author":"Zlotkin","year":"2007","journal-title":"East Afr. Med. J."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1017\/S0007114507705019","article-title":"The effects of maternal and infant vitamin A supplementation on vitamin A status: A randomised trial in Kenya","volume":"98","author":"Ayah","year":"2007","journal-title":"Br. J. Nutr."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/j.1651-2227.1995.tb13781.x","article-title":"Bulging fontanelle after supplementation with 25,000 IU of vitamin A in infancy using immunization contacts","volume":"84","author":"Baqui","year":"1995","journal-title":"Acta Paediatr."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"4150","DOI":"10.1093\/jn\/133.12.4150","article-title":"Simultaneous weekly supplementation of iron and zinc is associated with lower morbidity due to diarrhea and acute lower respiratory infection in Bangladeshi infants","volume":"133","author":"Baqui","year":"2003","journal-title":"J. Nutr."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/mcn.12163","article-title":"In-home fortification with 2.5 mg iron as NaFeEDTA does not reduce anaemia but increases weight gain: A randomised controlled trial in Kenyan infants","volume":"11","author":"Moretti","year":"2015","journal-title":"Matern. Child Nutr."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/sj.ejcn.1602682","article-title":"Effects of bovine serum concentrate, with or without supplemental micronutrients, on the growth, morbidity, and micronutrient status of young children in a low-income, peri-urban Guatemalan community","volume":"62","author":"Begin","year":"2008","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1093\/jn\/127.7.1333","article-title":"Zinc supplementation affects the activity patterns of rural Guatemalan infants","volume":"127","author":"Bentley","year":"1997","journal-title":"J. Nutr."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/sj.ejcn.1600888","article-title":"Effect of daily iron supplementation on iron status, cell-mediated immunity, and incidence of infections in 6-36 month old Togolese children","volume":"54","author":"Berger","year":"2000","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/sj.ejcn.1602336","article-title":"Efficacy of combined iron and zinc supplementation on micronutrient status and growth in Vietnamese infants","volume":"60","author":"Berger","year":"2006","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"e86","DOI":"10.1542\/peds.109.6.e86","article-title":"Substantial reduction in severe diarrheal morbidity by daily zinc supplementation in young north Indian children","volume":"109","author":"Bhandari","year":"2002","journal-title":"Pediatrics"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.3945\/ajcn.111.028704","article-title":"Randomized controlled trial of the effectiveness of a soybean-maize-sorghum-based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo","volume":"95","author":"Bisimwa","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0140-6736(05)67109-7","article-title":"Effect of weekly zinc supplements on incidence of pneumonia and diarrhoea in children younger than 2 years in an urban, low-income population in Bangladesh: Randomised controlled trial","volume":"366","author":"Brooks","year":"2005","journal-title":"Lancet"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1016\/j.nut.2013.05.023","article-title":"Mineral status of non-anemic Peruvian infants taking an iron and copper syrup with or without zinc from 6 to 18 months of age: A randomized controlled trial","volume":"29","author":"Caulfield","year":"2013","journal-title":"Nutrition"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/ejcn.2009.127","article-title":"Supplementing iron and zinc: Double blind, randomized evaluation of separate or combined delivery","volume":"64","author":"Chang","year":"2010","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0895-3988(10)60036-0","article-title":"Effect of in-home fortification of complementary feeding on intellectual development of Chinese children","volume":"23","author":"Chen","year":"2010","journal-title":"Biomed. Environ. Sci."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.nut.2013.03.025","article-title":"Effect of simultaneous supplementation of vitamin A and iron on diarrheal and respiratory tract infection in preschool children in Chengdu City, China","volume":"29","author":"Chen","year":"2013","journal-title":"Nutrition"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"440","DOI":"10.3177\/jnsv.54.440","article-title":"Effects of vitamin A, vitamin A plus iron and multiple micronutrient-fortified seasoning powder on preschool children in a suburb of Chongqing, China","volume":"54","author":"Chen","year":"2008","journal-title":"J. Nutr. Sci. Vitaminol. (Tokyo)"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.1093\/jn\/132.12.3693","article-title":"A randomized, 4-month mango and fat supplementation trial improved vitamin A status among young Gambian children","volume":"132","author":"Drammeh","year":"2002","journal-title":"J. Nutr."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1177\/15648265020233S142","article-title":"Domestic drinking water\u2014An effective way to prevent anemia among low socioeconomic families in Brazil","volume":"23","year":"2002","journal-title":"Food Nutr. Bull."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1046\/j.1365-3156.2000.00626.x","article-title":"Micronutrient and iron supplementation and effective antimalarial treatment synergistically improve childhood anaemia","volume":"5","author":"Ekvall","year":"2000","journal-title":"Trop. Med. Int. Health"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1093\/tropej\/48.5.280","article-title":"Effects of three different iron supplementations in term healthy infants after 5 months of life","volume":"48","author":"Ermis","year":"2002","journal-title":"J. Trop. Pediatr."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"5636","DOI":"10.3390\/nu6125636","article-title":"Zinc absorption from micronutrient powder is low but is not affected by iron in Kenyan infants","volume":"6","author":"Esamai","year":"2014","journal-title":"Nutrients"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1093\/ajcn\/82.5.1032","article-title":"Effect of a fortified maize-meal porridge on anemia, micronutrient status, and motor development of infants","volume":"82","author":"Faber","year":"2005","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_69","first-page":"301","article-title":"Zinc-iron, but not zinc-alone supplementation, increased linear growth of stunted infants with low haemoglobin","volume":"16","author":"Fahmida","year":"2007","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.2105\/AJPH.87.8.1359","article-title":"The effect of vitamin A supplementation on the growth of preschool children in the Sudan","volume":"87","author":"Fawzi","year":"1997","journal-title":"Am. J. Public Health"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.1016\/j.vaccine.2013.04.072","article-title":"High-dose vitamin A supplementation administered with vaccinations after 6 months of age: Sex-differential adverse reactions and morbidity","volume":"31","author":"Fisker","year":"2013","journal-title":"Vaccine"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/01.mpg.0000189363.07040.4b","article-title":"Double-blind, placebo-controlled trial comparing effects of supplementation with two different combinations of micronutrients delivered as sprinkles on growth, anemia, and iron deficiency in cambodian infants","volume":"42","author":"Giovannini","year":"2006","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1093\/tropej\/fms028","article-title":"Effect of iron supplementation on development of iron deficiency anemia in breastfed infants","volume":"58","author":"Gokcay","year":"2012","journal-title":"J. Trop. Pediatr."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/j.1651-2227.2003.tb02501.x","article-title":"Impact of zinc supplementation on diarrhoeal morbidity in rural children of West Bengal, India","volume":"92","author":"Gupta","year":"2003","journal-title":"Acta Paediatr."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/01.inf.0000258692.65485.d9","article-title":"Operational feasibility of implementing community-based zinc supplementation: Impact on childhood diarrheal morbidity","volume":"26","author":"Gupta","year":"2007","journal-title":"Pediatr. Infect. Dis. J."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1093\/ajcn\/74.3.381","article-title":"Randomized controlled trial of the effect of zinc supplementation on the mental development of Bangladeshi infants","volume":"74","author":"Hamadani","year":"2001","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3945\/ajcn.113.063883","article-title":"Linear growth increased in young children in an urban slum of Haiti: A randomized controlled trial of a lipid-based nutrient supplement","volume":"99","author":"Iannotti","year":"2014","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_78","first-page":"203","article-title":"A randomized placebo-controlled trial of iron supplementation in breastfed young infants initiated on complementary feeding: Effect on haematological status","volume":"22","author":"Nagpal","year":"2004","journal-title":"J. Health Popul. Nutr."},{"key":"ref_79","first-page":"1131","article-title":"Effectiveness of nutrition education, iron supplementation or both on iron status in children","volume":"40","author":"Kapur","year":"2003","journal-title":"Indian Pediatr."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0962-8479(95)90535-9","article-title":"Plasma retinol level, vitamin A supplementation and acute respiratory infections in children of 1-5 years old in a developing country. Respiratory Diseases Working Group","volume":"76","author":"Kartasasmita","year":"1995","journal-title":"Tuber. Lung Dis."},{"key":"ref_81","unstructured":"Donald, S. (2012). Acceptance and Effect of Ferrous Fumarate Containing Micronutrient Sprinkles on Anemia, Iron Deficiency and Anthropometrics in Honduran Children. Anemia, InTech."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1093\/ajcn\/68.6.1261","article-title":"Effect of zinc supplementation on growth and body composition of Ugandan preschool children: A randomized, controlled, intervention trial","volume":"68","author":"Kikafunda","year":"1998","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/1475-2891-10-129","article-title":"Effect of daily versus weekly home fortification with multiple micronutrient powder on haemoglobin concentration of young children in a rural area, Lao People\u2019s Democratic Republic: A randomised trial","volume":"10","author":"Kounnavong","year":"2011","journal-title":"Nutr. J."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"2855","DOI":"10.1017\/S1368980018001441","article-title":"Effectiveness of zinc-fortified water on zinc intake, status and morbidity in Kenyan pre-school children: A randomised controlled trial","volume":"21","author":"Kujinga","year":"2018","journal-title":"Public Health Nutr."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1093\/ajcn\/70.3.391","article-title":"A randomized, community-based trial of the effects of improved, centrally processed complementary foods on growth and micronutrient status of Ghanaian infants from 6 to 12 mo of age","volume":"70","author":"Lartey","year":"1999","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"660S","DOI":"10.1093\/jn\/135.3.660S","article-title":"Multiple micronutrient supplementation improves anemia, micronutrient nutrient status, and growth of Vietnamese infants: Double-blind, randomized, placebo-controlled trial","volume":"135","author":"Hop","year":"2005","journal-title":"J. Nutr."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1093\/ajcn\/77.4.883","article-title":"A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: Interactions between iron and zinc","volume":"77","author":"Lind","year":"2003","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.3945\/ajcn.111.012278","article-title":"Plasma zinc concentration responds to short-term zinc supplementation, but not zinc fortification, in young children in Senegal1,2","volume":"93","author":"Lo","year":"2011","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1093\/ajcn.83.3.693","article-title":"A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mexico","volume":"83","author":"Long","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1017\/S0007114507257757","article-title":"Supplementation with vitamin A reduces watery diarrhoea and respiratory infections in Mexican children","volume":"97","author":"Long","year":"2007","journal-title":"Br. J. Nutr."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"646S","DOI":"10.1093\/jn\/135.3.646S","article-title":"Efficacy of multiple micronutrient supplementation for improving anemia, micronutrient status, growth, and morbidity of Peruvian infants","volume":"135","author":"Cusirramos","year":"2005","journal-title":"J. Nutr."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"612","DOI":"10.3945\/jn.115.223917","article-title":"Low-Dose Iron Supplementation in Infancy Modestly Increases Infant Iron Status at 9 Mo without Decreasing Growth or Increasing Illness in a Randomized Clinical Trial in Rural China","volume":"146","author":"Lozoff","year":"2016","journal-title":"J. Nutr."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/S0022-3476(96)70070-7","article-title":"Iron-deficiency anemia and infant development: Effects of extended oral iron therapy","volume":"129","author":"Lozoff","year":"1996","journal-title":"J. Pediatr."},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Luabeya, K.K., Mpontshane, N., Mackay, M., Ward, H., Elson, I., Chhagan, M., Tomkins, A., Van den Broeck, J., and Bennish, M.L. (2007). Zinc or multiple micronutrient supplementation to reduce diarrhea and respiratory disease in South African children: A randomized controlled trial. PLoS ONE, 2.","DOI":"10.1371\/journal.pone.0000541"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.3945\/jn.112.157578","article-title":"Maize porridge enriched with a micronutrient powder containing low-dose iron as NaFeEDTA but not amaranth grain flour reduces anemia and iron deficiency in Kenyan preschool children","volume":"142","author":"Moretti","year":"2012","journal-title":"J. Nutr."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.3945\/jn.114.208181","article-title":"Provision of 10-40 g\/d Lipid-Based Nutrient Supplements from 6 to 18 Months of Age Does Not Prevent Linear Growth Faltering in Malawi","volume":"145","author":"Maleta","year":"2015","journal-title":"J. Nutr."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1542\/peds.2012-2980","article-title":"Short-course prophylactic zinc supplementation for diarrhea morbidity in infants of 6 to 11 months","volume":"132","author":"Malik","year":"2013","journal-title":"Pediatrics"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/S0140-6736(11)61650-4","article-title":"Effect on the incidence of pneumonia of vitamin D supplementation by quarterly bolus dose to infants in Kabul: A randomised controlled superiority trial","volume":"379","author":"Maroof","year":"2012","journal-title":"Lancet"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.3945\/jn.114.196139","article-title":"Lipid-based nutrient supplements do not affect the risk of malaria or respiratory morbidity in 6- to 18-month-old Malawian children in a randomized controlled trial","volume":"144","author":"Mangani","year":"2014","journal-title":"J. Nutr."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.aller.2015.12.006","article-title":"Effects of zinc supplementation in the prevention of respiratory tract infections and diarrheal disease in Colombian children: A 12-month randomised controlled trial","volume":"44","year":"2016","journal-title":"Allergol. Immunopathol. (Madr.)"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1016\/S0140-6736(03)13504-0","article-title":"Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: A randomised placebo-controlled trial","volume":"361","author":"Massaga","year":"2003","journal-title":"Lancet"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"2998","DOI":"10.1017\/S1368980017001811","article-title":"Effects of lipid-based nutrient supplements v. micronutrient powders on nutritional and developmental outcomes among Peruvian infants","volume":"20","author":"Matias","year":"2017","journal-title":"Public Health Nutr."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.3945\/jn.109.115154","article-title":"Neither a zinc supplement nor phytate-reduced maize nor their combination enhance growth of 6- to 12-month-old Guatemalan infants","volume":"140","author":"Mazariegos","year":"2010","journal-title":"J. Nutr."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.3945\/jn.115.212308","article-title":"Daily Zinc but Not Multivitamin Supplementation Reduces Diarrhea and Upper Respiratory Infections in Tanzanian Infants: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial","volume":"145","author":"McDonald","year":"2015","journal-title":"J. Nutr."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/S0140-6736(97)04229-3","article-title":"Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infants","volume":"350","author":"Menendez","year":"1997","journal-title":"Lancet"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1093\/jn\/137.4.1023","article-title":"Micronutrient Sprinkles reduce anemia among 9- to 24-mo-old children when delivered through an integrated health and nutrition program in rural Haiti","volume":"137","author":"Menon","year":"2007","journal-title":"J. Nutr."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1093\/jn\/127.8.1451","article-title":"Long-term oral supplementation with iron is not harmful for young children in a poor community of Bangladesh","volume":"127","author":"Mitra","year":"1997","journal-title":"J. Nutr."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1136\/bmj.322.7302.1567","article-title":"Effect of zinc supplementation on malaria and other causes of morbidity in west African children: Randomised double blind placebo controlled trial","volume":"322","author":"Muller","year":"2001","journal-title":"BMJ"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s13690-016-0121-4","article-title":"Vitamin A status and body pool size of infants before and after consuming fortified home-based complementary foods","volume":"74","author":"Newton","year":"2016","journal-title":"Arch. Public Health"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1093\/ajcn\/64.5.694","article-title":"Effect of improved vitamin A status on response to iron supplementation in Pakistani infants","volume":"64","author":"Paracha","year":"1996","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/0963748031000092161","article-title":"The effect of a micronutrient-fortified complementary food on micronutrient status, growth and development of 6- to 12-month-old disadvantaged urban South African infants","volume":"54","author":"Oelofse","year":"2003","journal-title":"Int. J. Food Sci. Nutr."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/09637486.2010.495710","article-title":"Point-of-use micronutrient fortification: Lessons learned in implementing a preschool-based pilot trial in South Africa","volume":"62","author":"Ogunlade","year":"2011","journal-title":"Int. J. Food Sci. Nutr."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1017\/S1368980010000911","article-title":"Effect of an improved local ingredient-based complementary food fortified or not with iron and selected multiple micronutrients on Hb concentration","volume":"13","author":"Ouedraogo","year":"2010","journal-title":"Public Health Nutr."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1093\/ajcn\/86.4.1094","article-title":"Fortified complementary foods with or without alpha-amylase treatment increase hemoglobin but do not reduce breast milk intake of 9-mo-old Zambian infants","volume":"86","author":"Owino","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/1475-2891-12-131","article-title":"Impact of vitamin A with zinc supplementation on malaria morbidity in Ghana","volume":"12","author":"Newton","year":"2013","journal-title":"Nutr. J."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1136\/gutjnl-2017-314418","article-title":"Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: A randomised controlled study in Kenyan infants","volume":"66","author":"Paganini","year":"2017","journal-title":"Gut"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1093\/ajcn\/65.4.1057","article-title":"Effective community intervention to improve hemoglobin status in preschoolers receiving once-weekly iron supplementation","volume":"65","author":"Palupi","year":"1997","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1001\/archpedi.162.7.619","article-title":"Complementary feeding with fortified spread and incidence of severe stunting in 6- to 18-month-old rural Malawians","volume":"162","author":"Phuka","year":"2008","journal-title":"Arch. Pediatr. Adolesc. Med."},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Radhakrishna, K.V., Hemalatha, R., Geddam, J.J., Kumar, P.A., Balakrishna, N., and Shatrugna, V. (2013). Effectiveness of zinc supplementation to full term normal infants: A community based double blind, randomized, controlled, clinical trial. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0061486"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1093\/jn\/129.7.1319","article-title":"Long-term supplementation with iron does not enhance growth in malnourished Bangladeshi children","volume":"129","author":"Rahman","year":"1999","journal-title":"J. Nutr."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1093\/jn\/126.3.628","article-title":"Acute respiratory infections prevent improvement of vitamin A status in young infants supplemented with vitamin A","volume":"126","author":"Rahman","year":"1996","journal-title":"J. Nutr."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1136\/bmj.323.7308.314","article-title":"Simultaneous zinc and vitamin A supplementation in Bangladeshi children: Randomised double blind controlled trial","volume":"323","author":"Rahman","year":"2001","journal-title":"BMJ"},{"key":"ref_123","first-page":"264","article-title":"Effect of iron fortification of nursery complementary food on iron status of infants in the DPRKorea","volume":"17","author":"Rim","year":"2008","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/ajcn\/74.5.657","article-title":"Multiple micronutrient supplementation increases the growth of Mexican infants","volume":"74","author":"Rivera","year":"2001","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/ajcn\/65.1.13","article-title":"Zinc supplementation reduced morbidity, but neither zinc nor iron supplementation affected growth or body composition of Mexican preschoolers","volume":"65","author":"Rosado","year":"1997","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1017\/S1368980010003344","article-title":"Effectiveness of the nutritional supplement used in the Mexican Oportunidades programme on growth, anaemia, morbidity and cognitive development in children aged 12-24 months","volume":"14","author":"Rosado","year":"2011","journal-title":"Public Health Nutr."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.2105\/AJPH.85.9.1246","article-title":"Child morbidity and mortality following vitamin A supplementation in Ghana: Time since dosing, number of doses, and time of year","volume":"85","author":"Ross","year":"1995","journal-title":"Am. J. Public Health"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.jped.2012.11.004","article-title":"Zinc and other micronutrients supplementation through the use of sprinkles: Impact on the occurrence of diarrhea and respiratory infections in institutionalized children","volume":"89","author":"Sampaio","year":"2013","journal-title":"J. Pediatr. (Rio J.)"},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/ajcn\/66.2.413","article-title":"Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea\u2014A community-based, double-blind, controlled trial","volume":"66","author":"Sazawal","year":"1997","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0140-6736(06)67962-2","article-title":"Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: Community-based, randomised, placebo-controlled trial","volume":"367","author":"Sazawal","year":"2006","journal-title":"Lancet"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1136\/bmj.39035.482396.55","article-title":"Effects of fortified milk on morbidity in young children in north India: Community based, randomised, double masked placebo controlled trial","volume":"334","author":"Sazawal","year":"2007","journal-title":"BMJ"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1542\/peds.104.1.e1","article-title":"The beneficial effects of weekly low-dose vitamin A supplementation on acute lower respiratory infections and diarrhea in Ecuadorian children","volume":"104","author":"Sempertegui","year":"1999","journal-title":"Pediatrics"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1097\/MPG.0b013e318167b03b","article-title":"Ferrous gluconate and ferrous sulfate added to a complementary food distributed by the Mexican nutrition program Oportunidades have a comparable efficacy to reduce iron deficiency in toddlers","volume":"47","author":"Villalpando","year":"2008","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0140-6736(98)08293-2","article-title":"Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: A randomised trial","volume":"354","author":"Shankar","year":"1999","journal-title":"Lancet"},{"key":"ref_135","first-page":"227","article-title":"Effects of zinc supplementation on 1- to 5-year old children","volume":"82","author":"Silva","year":"2006","journal-title":"J. Pediatr. (Rio J.)"},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"653S","DOI":"10.1093\/jn\/135.3.653S","article-title":"Efficacy of multiple micronutrient supplementation for improving anemia, micronutrient status, and growth in South African infants","volume":"135","author":"Smuts","year":"2005","journal-title":"J. Nutr."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1136\/bmj.323.7326.1389","article-title":"Effects of iron supplementation and anthelmintic treatment on motor and language development of preschool children in Zanzibar: Double blind, placebo controlled study","volume":"323","author":"Stoltzfus","year":"2001","journal-title":"BMJ"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.jtemb.2014.07.009","article-title":"Effect of probiotic L. plantarum IS-10506 and zinc supplementation on humoral immune response and zinc status of Indonesian pre-school children","volume":"28","author":"Surono","year":"2014","journal-title":"J. Trace Elem. Med. Biol."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"731","DOI":"10.3945\/ajcn.113.059592","article-title":"Folic acid and vitamin B-12 supplementation and common infections in 6-30-mo-old children in India: A randomized placebo-controlled trial","volume":"98","author":"Taneja","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_140","doi-asserted-by":"crossref","unstructured":"Teshome, E.M., Andang\u2019o, P.E.A., Osoti, V., Terwel, S.R., Otieno, W., Demir, A.Y., Prentice, A.M., and Verhoef, H. (2017). Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: A randomised, placebo-controlled, non-inferiority trial in Kenyan children. BMC Med., 15.","DOI":"10.1186\/s12916-017-0839-z"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1093\/ajcn\/69.1.80","article-title":"Effect of daily and weekly micronutrient supplementation on micronutrient deficiencies and growth in young Vietnamese children","volume":"69","author":"Thu","year":"1999","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1016\/S0140-6736(00)02348-5","article-title":"Zinc supplementation and stunted infants in Ethiopia: A randomised controlled trial","volume":"355","author":"Umeta","year":"2000","journal-title":"Lancet"},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"639S","DOI":"10.1093\/jn\/135.3.639S","article-title":"Multiple micronutrient supplements improve micronutrient status and anemia but not growth and morbidity of Indonesian infants: A randomized, double-blind, placebo-controlled trial","volume":"135","author":"Untoro","year":"2005","journal-title":"J. Nutr."},{"key":"ref_144","first-page":"279","article-title":"Effect of vitamin A supplementation to mother and infant on morbidity in infancy","volume":"33","author":"Venkatarao","year":"1996","journal-title":"Indian Pediatr."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"6606","DOI":"10.3390\/nu7085302","article-title":"The Long Term Impact of Micronutrient Supplementation during Infancy on Cognition and Executive Function Performance in Pre-School Children","volume":"7","author":"Qualter","year":"2015","journal-title":"Nutrients"},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1093\/jn\/136.9.2405","article-title":"Iron and zinc supplementation improved iron and zinc status, but not physical growth, of apparently healthy, breast-fed infants in rural communities of northeast Thailand","volume":"136","author":"Wasantwisut","year":"2006","journal-title":"J. Nutr."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jpeds.2011.06.051","article-title":"Short-term zinc supplementation with dispersible tablets or zinc sulfate solution yields similar positive effects on plasma zinc concentration of young children in Burkina Faso: A randomized controlled trial","volume":"160","author":"Wessells","year":"2012","journal-title":"J. Pediatr."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/ajcn\/77.3.651","article-title":"Redistribution of vitamin A after iron supplementation in Indonesian infants","volume":"77","author":"Wieringa","year":"2003","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/00043426-200405000-00005","article-title":"Efficacy of daily and weekly iron supplementation on iron status in exclusively breast-fed infants","volume":"26","author":"Yurdakok","year":"2004","journal-title":"J. Pediatr. Hematol. Oncol."},{"key":"ref_150","first-page":"108","article-title":"Use of microencapsulated iron(II) fumarate sprinkles to prevent recurrence of anaemia in infants and young children at high risk","volume":"81","author":"Zlotkin","year":"2003","journal-title":"Bull. World Health Organ."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1093\/jn\/127.4.574","article-title":"Infant survival is improved by oral iodine supplementation","volume":"127","author":"Cobra","year":"1997","journal-title":"J. Nutr."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1093\/jn\/126.2.434","article-title":"Vitamin A supplementation fails to reduce incidence of acute respiratory illness and diarrhea in preschool-age Indonesian children","volume":"126","author":"Dibley","year":"1996","journal-title":"J. Nutr."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"2860","DOI":"10.1093\/jn\/131.11.2860","article-title":"Effects of iron and zinc supplementation in Indonesian infants on micronutrient status and growth","volume":"131","author":"Dijkhuizen","year":"2001","journal-title":"J. Nutr."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1067\/mpd.2001.112895","article-title":"Iron supplementation of breast-fed Honduran and Swedish infants from 4 to 9 months of age","volume":"138","author":"Domellof","year":"2001","journal-title":"J. Pediatr."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/sj.ejcn.1601126","article-title":"Impact of iron supplementation and deworming on growth performance in preschool Beninese children","volume":"55","author":"Dossa","year":"2001","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jpeds.2018.11.022","article-title":"Effects of Daily Zinc, Daily Multiple Micronutrient Powder, or Therapeutic Zinc Supplementation for Diarrhea Prevention on Physical Growth, Anemia, and Micronutrient Status in Rural Laotian Children: A Randomized Controlled Trial","volume":"207","author":"Barffour","year":"2019","journal-title":"J. Pediatr."},{"key":"ref_157","first-page":"55","article-title":"To compare prophylactic zinc supplementation versus placebo in terms of frequency of diarrhea in infants of 6\u201311 months","volume":"29","author":"Noor","year":"2018","journal-title":"Med. Forum Mon."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1093\/ajcn\/nqy282","article-title":"Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: A randomized controlled trial","volume":"109","author":"Smuts","year":"2019","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/ajcn\/72.1.146","article-title":"Hyporetinolemia and acute phase proteins in children with and without xerophthalmia","volume":"72","author":"Semba","year":"2000","journal-title":"Am. J. Nutr."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1093\/jn\/136.10.2633","article-title":"Fortifying milk with ferrous gluconate and zinc oxide in a public nutrition program reduced the prevalence of anemia in toddlers","volume":"136","author":"Villalpando","year":"2006","journal-title":"J. Nutr."},{"key":"ref_161","first-page":"280","article-title":"Oral Zinc Supplementation Positively Affects Linear Growth, But not Weight, in Children 6\u201324 Months of Age","volume":"5","author":"Abdollahi","year":"2014","journal-title":"Int. J. Prev. Med."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"e1191","DOI":"10.1542\/peds.2010-2160","article-title":"A cluster-randomized evaluation of a responsive stimulation and feeding intervention in bangladesh","volume":"127","author":"Aboud","year":"2011","journal-title":"Pediatrics"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/ejcn.2010.52","article-title":"The effect of nutritional supplementation on physical activity and exploratory behavior of Mexican infants aged 8\u201312 months","volume":"64","author":"Aburto","year":"2010","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0271-5317(95)00034-G","article-title":"Vitamin a administration and preschool child mortality","volume":"15","author":"Agarwal","year":"1995","journal-title":"Nutr. Res."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1017\/S1368980008002619","article-title":"Effectiveness of a community-based intervention to improve nutrition in young children in Senegal: A difference in difference analysis","volume":"12","author":"Alderman","year":"2009","journal-title":"Public Health Nutr."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1093\/tropej\/fmt071","article-title":"Assessment of drinking water fortification with iron plus ascorbic Acid or ascorbic Acid alone in daycare centers as a strategy to control iron-deficiency anemia and iron deficiency: A randomized blind clinical study","volume":"60","author":"Ramos","year":"2014","journal-title":"J. Trop. Pediatr."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1093\/tropej\/fms003","article-title":"Milk-based cornstarch porridge fortified with iron is effective in reducing anemia: A randomized, double-blind, placebo-controlled trial","volume":"58","author":"Arcanjo","year":"2012","journal-title":"J. Trop. Pediatr."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"g5785","DOI":"10.1136\/bmj.g5785","article-title":"Using the infrastructure of a conditional cash transfer program to deliver a scalable integrated early child development program in Colombia: Cluster randomized controlled trial","volume":"349","author":"Attanasio","year":"2014","journal-title":"BMJ"},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/S0140-6736(12)62125-4","article-title":"Vitamin A supplementation every 6 months with retinol in 1 million pre-school children in north India: DEVTA, a cluster-randomised trial","volume":"381","author":"Awasthi","year":"2013","journal-title":"Lancet"},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1590\/S0102-311X2009000200007","article-title":"[Effect of weekly rice fortification with iron on anemia prevalence and hemoglobin concentration among children attending public daycare centers in Rio de Janeiro, Brazil]","volume":"25","author":"Bagni","year":"2009","journal-title":"Cad. Saude Publica"},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0104-4230(12)70164-1","article-title":"Double-blind randomized controlled trial of rolls fortified with microencapsulated iron","volume":"58","author":"Barbosa","year":"2012","journal-title":"Rev. Assoc. Med. Bras. (1992)"},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"124","DOI":"10.3945\/jn.115.218917","article-title":"A Randomized Controlled Trial Offering Higher- Compared with Lower-Dairy Second Meals Daily in Preschools in Guinea-Bissau Demonstrates an Attendance-Dependent Increase in Weight Gain for Both Meal Types and an Increase in Mid-Upper Arm Circumference for the Higher-Dairy Meal","volume":"146","author":"Batra","year":"2016","journal-title":"J. Nutr."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1377\/hlthaff.2017.0281","article-title":"Microfinance Institutions\u2019 Successful Delivery Of Micronutrient Powders: A Randomized Trial In Rural Haiti","volume":"36","author":"Baum","year":"2017","journal-title":"Health Aff. (Millwood)"},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.3945\/jn.116.230128","article-title":"Comparison of Preventive and Therapeutic Zinc Supplementation in Young Children in Burkina Faso: A Cluster-Randomized, Community-Based Trial","volume":"146","author":"Becquey","year":"2016","journal-title":"J. Nutr."},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1017\/S0007114517003658","article-title":"Introduction of iodised salt benefits infants\u2019 mental development in a community-based cluster-randomised effectiveness trial in Ethiopia","volume":"119","author":"Bougma","year":"2018","journal-title":"Br. J. Nutr."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1177\/156482650502600201","article-title":"Studies on the effectiveness of NaFeEDTA-fortified soy sauce in controlling iron deficiency: A population-based intervention trial","volume":"26","author":"Chen","year":"2005","journal-title":"Food Nutr. Bull."},{"key":"ref_177","first-page":"3","article-title":"Effects of vitamin A, vitamin A plus zinc, and multiple micronutrients on anemia in preschool children in Chongqing, China","volume":"21","author":"Chen","year":"2012","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1093\/ije\/dyv155","article-title":"Effect of fortified complementary food supplementation on child growth in rural Bangladesh: A cluster-randomized trial","volume":"44","author":"Christian","year":"2015","journal-title":"Int. J. Epidemiol."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1177\/156482650502600302","article-title":"Effect of fortification of drinking water with iron plus ascorbic acid or with ascorbic acid alone on hemoglobin values and anthropometric indicators in preschool children in day-care centers in Southeast Brazil","volume":"26","author":"Crott","year":"2005","journal-title":"Food Nutr. Bull."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"944","DOI":"10.3945\/ajcn.116.147942","article-title":"Lipid-based nutrient supplementation in the first 1000 d improves child growth in Bangladesh: A cluster-randomized effectiveness trial","volume":"105","author":"Dewey","year":"2017","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1186\/s12936-015-0872-3","article-title":"The effect of iron-fortified complementary food and intermittent preventive treatment of malaria on anaemia in 12- to 36-month-old children: A cluster-randomised controlled trial","volume":"14","author":"Glinz","year":"2015","journal-title":"Malar. J."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"S259","DOI":"10.1590\/S0102-311X2008001400011","article-title":"Treatment and prevention of anemia with ferrous sulfate plus folic acid in children attending daycare centers in Goiania, Goias State, Brazil: A randomized controlled trial","volume":"24","author":"Hadler","year":"2008","journal-title":"Cad. Saude Publica"},{"key":"ref_183","doi-asserted-by":"crossref","unstructured":"Hess, S.Y., Abbeddou, S., Jimenez, E.Y., Some, J.W., Vosti, S.A., Ouedraogo, Z.P., Guissou, R.M., Ouedraogo, J.B., and Brown, K.H. (2015). Small-quantity lipid-based nutrient supplements, regardless of their zinc content, increase growth and reduce the prevalence of stunting and wasting in young burkinabe children: A cluster-randomized trial. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0122242"},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1515\/jpem.2010.094","article-title":"Long-term cereal-based nutritional supplementation improved the total spine bone mineral density amongst Sri Lankan preschool children: A randomized controlled study","volume":"23","author":"Hettiarachchi","year":"2010","journal-title":"J. Pediatr. Endocrinol. Metab."},{"key":"ref_185","doi-asserted-by":"crossref","unstructured":"Huybregts, L., Houngbe, F., Salpeteur, C., Brown, R., Roberfroid, D., Ait-Aissa, M., and Kolsteren, P. (2012). The effect of adding ready-to-use supplementary food to a general food distribution on child nutritional status and morbidity: A cluster-randomized controlled trial. PLoS Med., 9.","DOI":"10.1371\/journal.pmed.1001313"},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"e001227","DOI":"10.1136\/bmjgh-2018-001227","article-title":"Cost-effectiveness of community-based screening and treatment of moderate acute malnutrition in Mali","volume":"4","author":"Isanaka","year":"2019","journal-title":"BMJ Glob. Health"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1001\/archpediatrics.2012.1003","article-title":"Effect of micronutrient sprinkles on reducing anemia: A cluster-randomized effectiveness trial","volume":"166","author":"Jack","year":"2012","journal-title":"Arch. Pediatr. Adolesc. Med."},{"key":"ref_188","doi-asserted-by":"crossref","unstructured":"Le Port, A., Bernard, T., Hidrobo, M., Birba, O., Rawat, R., and Ruel, M.T. (2017). Delivery of iron-fortified yoghurt, through a dairy value chain program, increases hemoglobin concentration among children 24 to 59 months old in Northern Senegal: A cluster-randomized control trial. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0172198"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1590\/1413-81232017222.17322016","article-title":"Impact of rice fortified with iron, zinc, thiamine and folic acid on laboratory measurements of nutritional status of preschool children","volume":"22","author":"Santos","year":"2017","journal-title":"Ci\u00eancia Sa\u00fade Coletiva"},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1177\/156482651003100307","article-title":"Daily use of Sprinkles micronutrient powder for 2 months reduces anemia among children 6 to 36 months of age in the Kyrgyz Republic: A cluster-randomized trial","volume":"31","author":"Lundeen","year":"2010","journal-title":"Food Nutr. Bull."},{"key":"ref_191","doi-asserted-by":"crossref","unstructured":"Luo, R., Yue, A., Zhou, H., Shi, Y., Zhang, L., Martorell, R., Medina, A., Rozelle, S., and Sylvia, S. (2017). The effect of a micronutrient powder home fortification program on anemia and cognitive outcomes among young children in rural China: A cluster randomized trial. BMC Public Health, 17.","DOI":"10.1186\/s12889-017-4755-0"},{"key":"ref_192","doi-asserted-by":"crossref","unstructured":"Ma, J., Sun, Q., Liu, J., Hu, Y., Liu, S., Zhang, J., Sheng, X., and Hambidge, K.M. (2016). The Effect of Iron Fortification on Iron (Fe) Status and Inflammation: A Randomized Controlled Trial. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0167458"},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1024\/0300-9831.74.1.35","article-title":"The use of iron-fortified wheat flour to reduce anemia among the estate population in Sri Lanka","volume":"74","author":"Nestel","year":"2004","journal-title":"Int. J. Vitam. Nutr. Res."},{"key":"ref_194","first-page":"31","article-title":"[Efficacy of daily and weekly iron supplementation for the control of iron deficiency anaemia in infants in rural Vietnam]","volume":"12","author":"Nguyen","year":"2002","journal-title":"Sante"},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/tropej\/fms021","article-title":"Use of iron-fortified rice reduces anemia in infants","volume":"58","author":"Santos","year":"2012","journal-title":"J. Trop. Pediatr."},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/mcn.12173","article-title":"Adding multiple micronutrient powders to a homestead food production programme yields marginally significant benefit on anaemia reduction among young children in Nepal","volume":"11","author":"Osei","year":"2015","journal-title":"Matern. Child Nutr."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.3945\/jn.110.123711","article-title":"Complementary foods fortified with micronutrients prevent iron deficiency and anemia in Vietnamese infants","volume":"140","author":"Phu","year":"2010","journal-title":"J. Nutr."},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"431","DOI":"10.3945\/ajcn.2009.28104","article-title":"Effectiveness of a large-scale iron-fortified milk distribution program on anemia and iron deficiency in low-income young children in Mexico","volume":"91","author":"Rivera","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_199","first-page":"217","article-title":"Compliance with home-based fortification strategies for delivery of iron and zinc: Its effect on haematological and growth markers among 6-24 months old children in north India","volume":"32","author":"Sazawal","year":"2014","journal-title":"J. Health Popul. Nutr."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1079\/PHN2006841","article-title":"Short-term daily or weekly administration of micronutrient Sprinkles has high compliance and does not cause iron overload in Chinese schoolchildren: A cluster-randomised trial","volume":"9","author":"Sharieff","year":"2006","journal-title":"Public Health Nutr."},{"key":"ref_201","first-page":"413","article-title":"Effect of daily versus weekly iron folic acid supplementation on the haemoglobin levels of children 6 to 36 months of urban slums of Vadodara","volume":"2","author":"Sharma","year":"2011","journal-title":"Indian J. Community Med."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/ppe.12117","article-title":"Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6\u201318 months living in the rural region of Intibuca, Honduras","volume":"28","author":"Kinlaw","year":"2014","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1017\/S1368980017003858","article-title":"The WHO recommendation of home fortification of foods with multiple-micronutrient powders in children under 2 years of age and its effectiveness on anaemia and weight: A pragmatic cluster-randomized controlled trial","volume":"21","author":"Somasse","year":"2018","journal-title":"Public Health Nutr."},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0140-6736(13)60437-7","article-title":"Effect of provision of daily zinc and iron with several micronutrients on growth and morbidity among young children in Pakistan: A cluster-randomised trial","volume":"382","author":"Soofi","year":"2013","journal-title":"Lancet"},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0140-6736(06)67963-4","article-title":"Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: Community-based, cluster-randomised, placebo-controlled trial","volume":"367","author":"Tielsch","year":"2006","journal-title":"Lancet"},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1093\/ajcn\/85.4.1127","article-title":"Community-level micronutrient fortification of a food supplement in India: A controlled trial in preschool children aged 36\u201366 months","volume":"85","author":"Varma","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_207","first-page":"294","article-title":"Impact of micronutrients sprinkle on weight and height of children aged 6\u201336 months in Tonk district of Rajasthan state","volume":"26","author":"Vijay","year":"2014","journal-title":"Indian J Community Health"},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/ajcn\/62.1.143","article-title":"Mortality of infants < 6 mo of age supplemented with vitamin A: A randomized, double-masked trial in Nepal","volume":"62","author":"West","year":"1995","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1001\/jama.2013.277129","article-title":"Effect of iron fortification on malaria incidence in infants and young children in Ghana: A randomized trial","volume":"310","author":"Zlotkin","year":"2013","journal-title":"JAMA"},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1080\/19390211.2018.1474987","article-title":"Micronutrient Fortification at Child-Care Centers Reduces Anemia in Young Children","volume":"16","author":"Arcanjo","year":"2019","journal-title":"J. Diet. Suppl."},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"e1257","DOI":"10.1016\/S2214-109X(19)30317-1","article-title":"Effects of nutritional supplementation and home visiting on growth and development in young children in Madagascar: A cluster-randomised controlled trial","volume":"7","author":"Galasso","year":"2019","journal-title":"Lancet Glob. Health"},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.1017\/jns.2019.18","article-title":"A macro- and micronutrient-fortified complementary food supplement reduced acute infection, improved haemoglobin and showed a dose-response effect in improving linear growth: A 12-month cluster randomised trial","volume":"8","author":"Ghosh","year":"2019","journal-title":"J. Nutr. Sci."},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1017\/S000711451800140X","article-title":"Effectiveness of a home fortification programme with multiple micronutrients on infant and young child development: A cluster-randomised trial in rural Bihar, India","volume":"120","author":"Larson","year":"2018","journal-title":"Br. J. Nutr."},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.3945\/ajcn.111.030072","article-title":"Selling Sprinkles micronutrient powder reduces anemia, iron deficiency, and vitamin A deficiency in young children in Western Kenya: A cluster-randomized controlled trial","volume":"95","author":"Suchdev","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"e302","DOI":"10.1016\/S2214-109X(17)30490-4","article-title":"Effects of water quality, sanitation, handwashing, and nutritional interventions on diarrhoea and child growth in rural Bangladesh: A cluster randomised controlled trial","volume":"6","author":"Luby","year":"2018","journal-title":"Lancet Glob. Health"},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"e316","DOI":"10.1016\/S2214-109X(18)30005-6","article-title":"Effects of water quality, sanitation, handwashing, and nutritional interventions on diarrhoea and child growth in rural Kenya: A cluster-randomised controlled trial","volume":"6","author":"Null","year":"2018","journal-title":"Lancet Glob. Health"},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1093\/jn\/nxy138","article-title":"PROCOMIDA, a Food-Assisted Maternal and Child Health and Nutrition Program, Reduces Child Stunting in Guatemala: A Cluster-Randomized Controlled Intervention Trial","volume":"148","author":"Olney","year":"2018","journal-title":"J. Nutr."},{"key":"ref_218","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1007\/s12098-007-0130-y","article-title":"Impact of long-term oral iron supplementation in breast-fed infants","volume":"74","author":"Abdelrazik","year":"2007","journal-title":"Indian J. Pediatr."},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1590\/S0102-311X2000000100006","article-title":"Tolerance of vitamin A application associated with mass immunization of children in Northeast Brazil","volume":"16","author":"Assis","year":"2000","journal-title":"Cad. Saude Publica"},{"key":"ref_220","doi-asserted-by":"crossref","unstructured":"Cardoso, M.A., Augusto, R.A., Bortolini, G.A., Oliveira, C.S., Tietzman, D.C., Sequeira, L.A., Hadler, M.C., Peixoto Mdo, R., Muniz, P.T., and Vitolo, M.R. (2016). Effect of Providing Multiple Micronutrients in Powder through Primary Healthcare on Anemia in Young Brazilian Children: A Multicentre Pragmatic Controlled Trial. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0156194"},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1093\/jn\/138.2.379","article-title":"Growth and micronutrient status in children receiving a fortified complementary food","volume":"138","author":"Lutter","year":"2008","journal-title":"J. Nutr."},{"key":"ref_222","first-page":"53","article-title":"Long-term preventive mass prescription of weekly doses of iron sulfate may be highly effective to reduce endemic child anemia","volume":"22","author":"Monteiro","year":"2001","journal-title":"Rev. Bras. Epidemiol."},{"key":"ref_223","first-page":"S36","article-title":"Complementary food supplementation with a small-quantity of lipid-based nutrient supplements prevents stunting in 6\u201312-month-old infants in rural West Madura Island, Indonesia","volume":"25","author":"Muslihah","year":"2016","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"559","DOI":"10.14260\/Jemds\/2017\/119","article-title":"Effect of iron prophylaxis in preventing iron deficiency anaemia in term infants","volume":"6","author":"Nair","year":"2017","journal-title":"J. Evol. Med. Dent. Sci."},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"3039","DOI":"10.1017\/S1368980016001294","article-title":"Multiple micronutrients in powder delivered through primary health care reduce iron and vitamin A deficiencies in young Amazonian children","volume":"19","author":"Oliveira","year":"2016","journal-title":"Public Health Nutr."},{"key":"ref_226","first-page":"105487","article-title":"Impact of vitamin D supplementation model on the circulating levels of 25 (OH) D in Algerian children aged 1-23 months","volume":"196","author":"Dupre","year":"2019","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"S143","DOI":"10.1177\/15648265060274S405","article-title":"Protective effect of multimicronutrient supplementation against anemia among children, women, and adolescent girls in lower-income areas of Chiclayo, Peru","volume":"27","author":"Verona","year":"2006","journal-title":"Food Nutr. Bull."},{"key":"ref_228","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1111\/tmi.12706","article-title":"Effect of calcium and vitamin D on growth, rickets and Kashin-Beck disease in 0- to 5-year-old children in a rural area of central Tibet","volume":"21","author":"Rooze","year":"2016","journal-title":"Trop. Med. Int. Health"},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.socscimed.2018.02.003","article-title":"The impact of vitamin A supplementation in childhood on adult outcomes: An exploration of mechanisms, timing of exposure, and heterogeneous effects","volume":"201","author":"Acharya","year":"2018","journal-title":"Soc. Sci. Med."},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s12098-007-0074-2","article-title":"Impact of mass supplementation of vitamin A","volume":"74","author":"Swami","year":"2007","journal-title":"Indian J. Pediatr."},{"key":"ref_231","first-page":"193","article-title":"An evaluation of the ICDS food fortification in Uttarakhand","volume":"24","author":"Yadav","year":"2012","journal-title":"Indian J. Community Health"},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/nyas.12368","article-title":"Cost-benefit analysis of a micronutrient supplementation and early childhood stimulation program in Nicaragua","volume":"1308","author":"Palloni","year":"2014","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_233","doi-asserted-by":"crossref","unstructured":"Samuel, A., Brouwer, I.D., Feskens, E.J.M., Adish, A., Kebede, A., De-Regil, L.M., and Osendarp, S.J.M. (2018). Effectiveness of a Program Intervention with Reduced-Iron Multiple Micronutrient Powders on Iron Status, Morbidity and Growth in Young Children in Ethiopia. Nutrients, 10.","DOI":"10.3390\/nu10101508"},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0140-6736(96)12365-5","article-title":"Effect on infant mortality of iodination of irrigation water in a severely iodine-deficient area of China","volume":"350","author":"DeLong","year":"1997","journal-title":"Lancet"},{"key":"ref_235","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1093\/oxfordjournals.aje.a117724","article-title":"The role of universal distribution of vitamin A capsules in combatting vitamin A deficiency in Bangladesh","volume":"142","author":"Bloem","year":"1995","journal-title":"Am. J. Epidemiol."},{"key":"ref_236","doi-asserted-by":"crossref","unstructured":"Gebremedhin, S. (2014). Effect of a single high dose vitamin A supplementation on the hemoglobin status of children aged 6-59 months: Propensity score matched retrospective cohort study based on the data of Ethiopian Demographic and Health Survey 2011. BMC Pediatr, 14.","DOI":"10.1186\/1471-2431-14-79"},{"key":"ref_237","doi-asserted-by":"crossref","unstructured":"Fisker, A.B., Aaby, P., Rodrigues, A., Frydenberg, M., Bibby, B.M., and Benn, C.S. (2011). Vitamin A supplementation at birth might prime the response to subsequent vitamin A supplements in girls. Three year follow-up of a randomized trial. PLoS ONE, 6.","DOI":"10.1371\/journal.pone.0023265"},{"key":"ref_238","doi-asserted-by":"crossref","first-page":"b919","DOI":"10.1136\/bmj.b919","article-title":"Neonatal vitamin A supplementation for prevention of mortality and morbidity in infancy: Systematic review of randomised controlled trials","volume":"338","author":"Gogia","year":"2009","journal-title":"BMJ"},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1093\/ajcn\/80.4.903","article-title":"Iron and zinc supplementation promote motor development and exploratory behavior among Bangladeshi infants","volume":"80","author":"Black","year":"2004","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_240","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1093\/ajcn\/80.3.729","article-title":"A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: Effects on growth and development","volume":"80","author":"Lind","year":"2004","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_241","doi-asserted-by":"crossref","first-page":"636","DOI":"10.3945\/ajcn.110.002220","article-title":"Long-term effects of iron and zinc supplementation during infancy on cognitive function at 9 y of age in northeast Thai children: A follow-up study","volume":"93","author":"Pongcharoen","year":"2011","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_242","doi-asserted-by":"crossref","first-page":"e77","DOI":"10.1016\/S2214-109X(13)70046-9","article-title":"Effect of daily iron supplementation on health in children aged 4-23 months: A systematic review and meta-analysis of randomised controlled trials","volume":"1","author":"Pasricha","year":"2013","journal-title":"Lancet Glob. Health"},{"key":"ref_243","doi-asserted-by":"crossref","first-page":"E791","DOI":"10.1503\/cmaj.130628","article-title":"Effects of daily iron supplementation in primary-school-aged children: Systematic review and meta-analysis of randomized controlled trials","volume":"185","author":"Low","year":"2013","journal-title":"CMAJ"},{"key":"ref_244","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1542\/peds.2012-2256","article-title":"Effects of daily iron supplementation in 2- to 5-year-old children: Systematic review and meta-analysis","volume":"131","author":"Thompson","year":"2013","journal-title":"Pediatrics"},{"key":"ref_245","unstructured":"WHO (2016). Guideline: Daily Iron Supplementation in Infants and Children, World Health Organization."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/12\/2\/289\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T14:05:35Z","timestamp":1760364335000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/12\/2\/289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,21]]},"references-count":245,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2]]}},"alternative-id":["nu12020289"],"URL":"https:\/\/doi.org\/10.3390\/nu12020289","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,21]]}}}