{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T20:10:21Z","timestamp":1787256621895,"version":"build-2736575974"},"reference-count":69,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T00:00:00Z","timestamp":1580774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005285","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Goi\u00e1s","doi-asserted-by":"publisher","award":["201310267000003"],"award-info":[{"award-number":["201310267000003"]}],"id":[{"id":"10.13039\/501100005285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Dietary interventions can stabilize and\/or reverse bone mass loss. However, there are no reports on its effects on bone mineral density (BMD) in severely obese people, despite the vulnerability of this group to bone loss. We examine the effect of extra virgin olive oil supplementation and the traditional Brazilian diet (DieTBra) on BMD and levels of calcium, vitamin D, and parathyroid hormone (PTH) in severely obese adults. A randomized controlled trial followed-up with severely obese adults (n = 111, with mean body mass index 43.6 kg\/m2 \u00b1 4.5 kg\/m2) for 12 weeks. Study participants received either olive oil (52 mL\/day), DieTBra, or olive oil + DieTBra (52 mL\/day + DieTBra). BMD was assessed by total spine and hip dual-energy X-ray absorptiometry. After interventions, BMD means for total spine (p = 0.016) and total hip (p = 0.029) were higher in the DieTBra group than in the olive oil + DieTBra group. Final mean calcium levels were higher in the olive oil group compared to the olive oil + DieTBra group (p = 0.026). Findings suggest that DieTBra and extra virgin olive oil have positive effects on bone health in severely obese adults. The major study was registered at ClinicalTrials.gov (NCT02463435).<\/jats:p>","DOI":"10.3390\/nu12020403","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T03:18:48Z","timestamp":1580872728000},"page":"403","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Effect of Extra Virgin Olive Oil and Traditional Brazilian Diet on the Bone Health Parameters of Severely Obese Adults: A Randomized Controlled Trial"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1246-5572","authenticated-orcid":false,"given":"Camila Kellen de Souza","family":"Cardoso","sequence":"first","affiliation":[{"name":"The Postgraduate Program in Health Sciences, School of Social Sciences and Health, Nutrition Course, Pontifical Catholic University of Goi\u00e1s, Goi\u00e2nia, 74605-020 Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0045-6991","authenticated-orcid":false,"given":"Annelisa Silva e Alves de Carvalho","family":"Santos","sequence":"additional","affiliation":[{"name":"The Postgraduate Program in Health Sciences, Faculty of Medicine, Federal University of Goi\u00e1s, Goi\u00e2nia, 74605-220 Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4937-4284","authenticated-orcid":false,"given":"Lorena Pereira de Souza","family":"Rosa","sequence":"additional","affiliation":[{"name":"The Postgraduate Program in Health Sciences, Faculty of Medicine, Federal University of Goi\u00e1s, Goi\u00e2nia, 74605-220 Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9902-8227","authenticated-orcid":false,"given":"Carolina Rodrigues","family":"Mendon\u00e7a","sequence":"additional","affiliation":[{"name":"The Postgraduate Program in Health Sciences, Faculty of Medicine, Federal University of Goi\u00e1s, Goi\u00e2nia, 74605-220 Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5487-4649","authenticated-orcid":false,"given":"Priscila Valverde de Oliveira","family":"Vitorino","sequence":"additional","affiliation":[{"name":"The Postgraduate Program in Health Sciences, Professor of the School of Social Sciences and Health, Pontifical Catholic University of Goi\u00e1s, Goi\u00e2nia, 74605-020 Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1950-0817","authenticated-orcid":false,"given":"Maria do Ros\u00e1rio Gondim","family":"Peixoto","sequence":"additional","affiliation":[{"name":"The Postgraduate Program Nutrition and Health, Faculty of Nutrition, Federal University of Goi\u00e1s, Goi\u00e2nia, 74605-220 Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8839-4520","authenticated-orcid":false,"given":"\u00c9rika Aparecida","family":"Silveira","sequence":"additional","affiliation":[{"name":"The Postgraduate Program in Health Sciences, Faculty of Medicine, Federal University of Goi\u00e1s, Goi\u00e2nia, 74605-220 Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/S0140-6736(16)30054-X","article-title":"Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 192 million participants","volume":"387","author":"Collaboration","year":"2016","journal-title":"Lancet"},{"key":"ref_2","unstructured":"World Health Organization (2012). 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