{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:40:20Z","timestamp":1790106020180,"version":"4.0.1"},"reference-count":50,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG2E0101-CMRPG2E0103, CMRPG2J0171 and CORPG2F0011-13"],"award-info":[{"award-number":["CMRPG2E0101-CMRPG2E0103, CMRPG2J0171 and CORPG2F0011-13"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Study on the impact of pretreatment malnutrition on treatment outcomes in locally advanced head and neck cancer (LAHNC) patients is still lacking. We prospectively collected various malnutrition assessment methods including nutrition indexes, inflammatory biomarkers, and lean body mass index (LBMI) data before treatments. The one year mortality rate was assessed, and the factors associated with this outcome were investigated. Furthermore, the association between malnutrition assessment methods was examined. A total of 113 patients were enrolled. By prognostic stratification based on the prognostic nutritional index (PNI) and platelet-to-lymphocyte ratio (PLR) combination, the low PNI\/high PLR group had highest and the high PNI\/low PLR group had the lowest mortality rate. Furthermore, the PNI was positively correlated with the LBMI, and the PLR was inversely correlated with the LBMI. PNI and PLR were found to be independent prognostic factors of one year mortality and also associated with the loss of muscle.<\/jats:p>","DOI":"10.3390\/nu12030836","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T11:42:11Z","timestamp":1584704531000},"page":"836","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Determining Malnutrition Assessment Criteria to Predict One-Year Mortality for Locally Advanced Head and Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4662-1235","authenticated-orcid":false,"given":"Hang Huong","family":"Ling","sequence":"first","affiliation":[{"name":"Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung &amp; Chang Gung University, College of Medicine, Keelung 204, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5572-7897","authenticated-orcid":false,"given":"Kun-Yun","family":"Yeh","sequence":"additional","affiliation":[{"name":"Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung &amp; Chang Gung University, College of Medicine, Keelung 204, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1842-6179","authenticated-orcid":false,"given":"Shu-Hang","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou &amp; Chang Gung University, Taoyuan 333, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Hsu","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung &amp; Chang Gung University, College of Medicine, Keelung 204, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Hong","family":"Lai","sequence":"additional","affiliation":[{"name":"Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung &amp; Chang Gung University, College of Medicine, Keelung 204, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsung-Han","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung &amp; Chang Gung University, College of Medicine, Keelung 204, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5006-0277","authenticated-orcid":false,"given":"Pei-Hung","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung &amp; Chang Gung University, College of Medicine, Keelung 204, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0361-4548","authenticated-orcid":false,"given":"Wen-Chi","family":"Chou","sequence":"additional","affiliation":[{"name":"Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou &amp; Chang Gung University, College of Medicine, Taoyuan 333, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang-Ping","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Keelung 204, Taiwan"},{"name":"College of Medicine, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan"},{"name":"Osteoporosis Prevention and Treatment Center, Chang Gung Memorial Hospital, Keelung 204, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2318-8507","authenticated-orcid":false,"given":"Yu-Ching","family":"Lin","sequence":"additional","affiliation":[{"name":"Osteoporosis Prevention and Treatment Center, Chang Gung Memorial Hospital, Keelung 204, Taiwan"},{"name":"Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Keelung &amp; Chang Gung University, Keelung 204, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1002\/hed.20221","article-title":"Impact of nutrition on outcome: A prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy","volume":"27","author":"Ravasco","year":"2005","journal-title":"Head Neck"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1016\/j.joms.2013.04.028","article-title":"Nutritional considerations for head and neck cancer patients: A review of the literature","volume":"71","author":"Alshadwi","year":"2013","journal-title":"J. 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