{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:21:03Z","timestamp":1790544063202,"version":"4.1.0"},"reference-count":112,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T00:00:00Z","timestamp":1586476800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Enteral nutrition seems to play a significant role in the treatment of both adults and children with active Crohn\u2019s disease, and to a lesser degree in the treatment of patients with active ulcerative colitis. The inclusion of some special factors in the enteral nutrition formulas might increase the rate of the efficacy. Actually, enteral nutrition enriched in Transforming Growth Factor-\u03b2 reduced the activity index and maintained remission in patients with Crohn\u2019s disease. In addition, a number of experimental animal studies have shown that colostrum exerts a significantly positive result. Probiotics of a special type and a certain dosage could also reduce the inflammatory process in patients with active ulcerative colitis. Therefore, the addition of these factors in an enteral nutrition formula might increase its effectiveness. Although the use of these formulas is not supported by large clinical trials, it could be argued that their administration in selected cases as an exclusive diet or in combination with the drugs used in patients with inflammatory bowel disease could benefit the patient. In this review, the authors provide an update on the role of enteral nutrition, supplemented with Transforming Growth Factor-\u03b2, colostrum, and probiotics in patients with inflammatory bowel disease.<\/jats:p>","DOI":"10.3390\/nu12041048","type":"journal-article","created":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T04:45:31Z","timestamp":1586753131000},"page":"1048","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Enteral Nutrition Supplemented with Transforming Growth Factor-\u03b2, Colostrum, Probiotics, and Other Nutritional Compounds in the Treatment of Patients with Inflammatory Bowel Disease"],"prefix":"10.3390","volume":"12","author":[{"given":"John K.","family":"Triantafillidis","sequence":"first","affiliation":[{"name":"\u201cMetropolitan General\u201d Hospital, ZC 15562 Holargos, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Tzouvala","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology \u201cSt Panteleimon\u201d General Hospital, ZC 18454 Nicea, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Triantafyllidi","sequence":"additional","affiliation":[{"name":"\u201cMetropolitan General\u201d Hospital, ZC 15562 Holargos, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Di Caro, S., Fragkos, K.C., Keetarut, K., Koo, F.H., Sebepos-Rogers, G., Saravanapavan, H., Barragry, J., Rogers, J., Mehta, S.J., and Rahman, F. 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