{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T05:15:30Z","timestamp":1773551730148,"version":"3.50.1"},"reference-count":43,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,4,11]],"date-time":"2020-04-11T00:00:00Z","timestamp":1586563200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Competitive State Research Financing of the Expert Responsibility area of Tampere University Hospital","award":["-"],"award-info":[{"award-number":["-"]}]},{"DOI":"10.13039\/100008723","name":"Suomen L\u00e4\u00e4ketieteen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/100008723","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Foundation for Paediatric Research","award":["-"],"award-info":[{"award-number":["-"]}]},{"DOI":"10.13039\/501100004212","name":"P\u00e4ivikki ja Sakari Sohlbergin S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100004212","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005873","name":"Keliakialiitto","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100005873","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010746","name":"Finnish Dermatological Society","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/100010746","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The treatment of choice for dermatitis herpetiformis (DH), a cutaneous manifestation of coeliac disease, is a life-long gluten-free diet (GFD). In a GFD, wheat, rye and barley should be strictly avoided, but the role of oats is more controversial. This study aimed to investigate the safety and long-term quality of life and health effects of oat consumption in 312 long-term treated DH patients. Baseline data were gathered from patient records and follow-up data from questionnaires or interviews, and validated questionnaires were used to assess quality of life. We found that altogether 256 patients (82%) were consuming oats as part of their GFD at the follow-up. Long-term follow-up data showed that there were no differences in the presence of long-term illnesses, coeliac disease complications or the usage of medication between those consuming and not consuming oats. However, oat consumers had a better quality of life and reported ongoing gastrointestinal symptoms less frequently (4% vs 19%, p = 0.004) at the follow-up than those not consuming oats. The study established that oats are safe for DH patients and in the long-term seem to improve the quality of life of DH patients.<\/jats:p>","DOI":"10.3390\/nu12041060","type":"journal-article","created":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T04:45:31Z","timestamp":1586753131000},"page":"1060","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis"],"prefix":"10.3390","volume":"12","author":[{"given":"Anna","family":"Alakoski","sequence":"first","affiliation":[{"name":"Department of Dermatology, Tampere University Hospital, 33521 Tampere, Finland"},{"name":"Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaisa","family":"Hervonen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tampere University Hospital, 33521 Tampere, Finland"},{"name":"Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eriika","family":"Mansikka","sequence":"additional","affiliation":[{"name":"Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timo","family":"Reunala","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tampere University Hospital, 33521 Tampere, Finland"},{"name":"Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katri","family":"Kaukinen","sequence":"additional","affiliation":[{"name":"Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland"},{"name":"Department of Internal Medicine, Tampere University Hospital, 33521 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Kivel\u00e4","sequence":"additional","affiliation":[{"name":"Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilvi","family":"Laurikka","sequence":"additional","affiliation":[{"name":"Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1372-430X","authenticated-orcid":false,"given":"Heini","family":"Huhtala","sequence":"additional","affiliation":[{"name":"Faculty of Social Sciences, Tampere University, 33014 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalle","family":"Kurppa","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Tampere University Hospital, 33521 Tampere, Finland"},{"name":"Center for Child Health Research, Tampere University; 33521 Tampere, Finland"},{"name":"Department of Pediatrics, Sein\u00e4joki Central Hospital and the University Consortium of Sein\u00e4joki, 60220 Sein\u00e4joki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teea","family":"Salmi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tampere University Hospital, 33521 Tampere, Finland"},{"name":"Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, 33014 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.clindermatol.2011.03.010","article-title":"Dermatitis Herpetiformis","volume":"30","year":"2012","journal-title":"Clin. 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