{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T15:04:15Z","timestamp":1783609455856,"version":"3.55.0"},"reference-count":41,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,4,12]],"date-time":"2020-04-12T00:00:00Z","timestamp":1586649600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>There is still room for further studies analyzing the long-term health impact of specific dietary patterns observable in regions belonging to the Mediterranean area. The aim of the study is to evaluate how much a diet practiced in southern Italy is associated to a risk of mortality. The study population included 2472 participants first investigated in 1985, inquiring about their frequencies of intake of 29 foods using a self-administered questionnaire covering the previous year. The population was followed up for mortality until 31 December 2017. Cox-based risk modeling referred to single foods, food groups, the results of principal component analysis (PCA), and a priori indexes. Single food analysis revealed eggs, fatty meat, and fatty\/baked ham to be inversely associated with mortality. Furthermore, one of the 5 PCA derived dietary patterns, the \u201cFarmhouse\u201d pattern, showed a higher hazard ratio (HR), mostly driven by dairy products. In subsequent analyses, the increased risk of mortality for fresh cheese and decreased risk for fatty ham and eggs were confirmed. The a priori diet indexes (Italian Meddiet, Meddietscore, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean\u2013DASH Intervention for Neurodegenerative Delay diet (MIND) indexes) showed borderline inverse relationships. In a Mediterranean population with an overall healthy diet, foods such as eggs and fatty meat, reflecting dietary energy and wealth, played a role in prolonging the life of individuals. Our study confirms that some dairy products might have a detrimental role in mortality in the Mediterranean setting.<\/jats:p>","DOI":"10.3390\/nu12041070","type":"journal-article","created":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T04:45:31Z","timestamp":1586753131000},"page":"1070","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Traditional Dietary Patterns and Risk of Mortality in a Longitudinal Cohort of the Salus in Apulia Study"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9885-1185","authenticated-orcid":false,"given":"Roberta","family":"Zupo","sequence":"first","affiliation":[{"name":"Population Health Unit \u2014\u201cSalus in Apulia Study\u201d\u2014National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo","family":"Sardone","sequence":"additional","affiliation":[{"name":"Population Health Unit \u2014\u201cSalus in Apulia Study\u201d\u2014National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9140-673X","authenticated-orcid":false,"given":"Rossella","family":"Donghia","sequence":"additional","affiliation":[{"name":"Data Analysis Unit, National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6439-8228","authenticated-orcid":false,"given":"Fabio","family":"Castellana","sequence":"additional","affiliation":[{"name":"Population Health Unit \u2014\u201cSalus in Apulia Study\u201d\u2014National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9299-3211","authenticated-orcid":false,"given":"Luisa","family":"Lampignano","sequence":"additional","affiliation":[{"name":"Population Health Unit \u2014\u201cSalus in Apulia Study\u201d\u2014National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4767-5334","authenticated-orcid":false,"given":"Ilaria","family":"Bortone","sequence":"additional","affiliation":[{"name":"Population Health Unit \u2014\u201cSalus in Apulia Study\u201d\u2014National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Misciagna","sequence":"additional","affiliation":[{"name":"Population Health Unit \u2014\u201cSalus in Apulia Study\u201d\u2014National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"De Pergola","sequence":"additional","affiliation":[{"name":"Clinical Nutrition Unit, Medical Oncology, Department of Biomedical Science and Human Oncology, University of Bari, School of Medicine, Policlinico, Piazza Giulio Cesare 11, 70124 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7220-0656","authenticated-orcid":false,"given":"Francesco","family":"Panza","sequence":"additional","affiliation":[{"name":"Population Health Unit \u2014\u201cSalus in Apulia Study\u201d\u2014National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"},{"name":"Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, 70121 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1674-9724","authenticated-orcid":false,"given":"Madia","family":"Lozupone","sequence":"additional","affiliation":[{"name":"Population Health Unit \u2014\u201cSalus in Apulia Study\u201d\u2014National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"},{"name":"Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, 70121 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Passantino","sequence":"additional","affiliation":[{"name":"Department of Cardiology and 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Italy"},{"name":"German Institute of Human Nutrition Potsdam-Rehbr\u00fccke, 14558 Nuthetal, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluigi","family":"Giannelli","sequence":"additional","affiliation":[{"name":"Scientific direction, National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Castellana Grotte, 70013 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"g4490","DOI":"10.1136\/bmj.g4490","article-title":"Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: Systematic review and dose-response meta-analysis of prospective cohort studies","volume":"349","author":"Wang","year":"2014","journal-title":"BMJ"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Aune, D., Keum, N., Giovannucci, E., Fadnes, L.T., 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