{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T05:29:03Z","timestamp":1769750943866,"version":"3.49.0"},"reference-count":38,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T00:00:00Z","timestamp":1594857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Up to 60% of colorectal cancer (CRC) patients develop malnutrition, affecting treatment effectiveness, increasing toxicity, postoperative complications, hospital stay, and worsening health-related quality of life (HRQOL). This cross-sectional study analyzed data from 48 women and 65 men with CRC. We correlated scores of the scales from the questionnaires EORTC (European Organisation for Research and Treatment of Cancer) Quality of Life Questionnaire Core 30 (QLQ)-C30 and Colorectal Cancer module Colorectal 29 (QLQ-CR29) with patients\u2019 body composition and clinical and biochemical indicators of nutritional status. Results: Scores on quality of life were negatively associated with the lymphocyte count (rP = \u22120.386) and the fat trunk percentage (rP = \u22120.349) in the women\u2019s group. Scores on the physical and role functioning were inversely associated with the adiposity percentage (rP = \u22120.486 and rP = \u22120.411, respectively). In men, total skeletal muscle mass (SMM) was positively associated with emotional functioning (rP = 0.450); the trunk SMM was negatively related to fatigue (rP = \u22120.586), nausea and vomiting (rP = \u22120.469), pain (rP = \u22120.506), and financial difficulties (rP = \u22120.475); additionally, serum albumin was positively related to physical, emotional, and social functioning scales (rPs = 0.395, 0.453, and 0.363, respectively) and negatively to fatigue (rP = \u22120.362), nausea and vomiting (rP = \u22120.387), and appetite loss (rP = \u22120.347). Among the men, the reduced SMM and biochemical, nutritional parameters were related to low scores on the EORTC QLQ-C30 and QLQ-CR29 functioning scales. In conclusion, in patients with CRC, malnourishment could have a profound effect on the patients\u2019 functionality and QoL (quality of life).<\/jats:p>","DOI":"10.3390\/nu12072110","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T10:54:46Z","timestamp":1594896886000},"page":"2110","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Body Composition and Biochemical Parameters of Nutritional Status: Correlation with Health-Related Quality of Life in Patients with Colorectal Cancer"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5052-457X","authenticated-orcid":false,"given":"Luz-Ma-Adriana","family":"Balderas-Pe\u00f1a","sequence":"first","affiliation":[{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica 02, UMAE Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"},{"name":"Departamento de Morfolog\u00eda, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdG), Cuerpo Acad\u00e9mico UDG CA-874 \u201cCiencias morfol\u00f3gicas en el diagn\u00f3stico y tratamiento de la enfermedad\u201d, 950 Sierra Mojada, Gate 7, Building C, 1st level, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5986-2655","authenticated-orcid":false,"given":"Faviola","family":"Gonz\u00e1lez-Barba","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica 02, UMAE Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9209-1362","authenticated-orcid":false,"given":"Brenda-Eugenia","family":"Mart\u00ednez-Herrera","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica 02, UMAE Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"},{"name":"Hospital General de Zona (HGZ) #02 c\/MF \u201cDr. Francisco Padr\u00f3n Puyou\u201d, Delegaci\u00f3n Estatal San Luis Potos\u00ed, IMSS, Benigno Arriaga street and Melchor Ocampo S\/N, Colonia Tequisquiapan, San Luis Potos\u00ed, San Luis Potos\u00ed 78250, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulises-Rodrigo","family":"Palomares-Chac\u00f3n","sequence":"additional","affiliation":[{"name":"Servicio de Coloproctolog\u00eda, Unidad M\u00e9dica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Dur\u00e1n-Anguiano","sequence":"additional","affiliation":[{"name":"Servicio de Coloproctolog\u00eda, Unidad M\u00e9dica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3391-6907","authenticated-orcid":false,"given":"Mario","family":"Salazar-P\u00e1ramo","sequence":"additional","affiliation":[{"name":"Academia de Inmunolog\u00eda, Departamento de Fisiolog\u00eda, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdG), 950 Sierra Mojada, Gate 7, Building O, 1st level, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"G\u00f3mez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n de Disciplinas B\u00e1sicas para Salud, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdG), Sierra Mojada 950, Edificio N, Puerta 1, Planta Baja, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"D\u00e1valos-Cobi\u00e1n","sequence":"additional","affiliation":[{"name":"Departamento Cl\u00ednico de Gastroenterolog\u00eda Endosc\u00f3pica, Unidad M\u00e9dica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO,) Instituto Mexicano del Seguro Social (IMSS), 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3061-521X","authenticated-orcid":false,"given":"Arnulfo-Hern\u00e1n","family":"Nava-Zavala","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica 02, UMAE Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"},{"name":"Programa Internacional Facultad de Medicina, Universidad Aut\u00f3noma de Guadalajara, Av. Patria 1201, Lomas del Valle, Zapopan 45129, Mexico"},{"name":"Servicio de Inmunolog\u00eda y Reumatolog\u00eda, Divisi\u00f3n de Medicina Interna, Hospital General de Occidente, Secretaria de Salud Jalisco, Av. Zoquipan 1050, Zoquipan, Zapopan, Jalisco 45170, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo-Allan","family":"Hern\u00e1ndez-Ch\u00e1vez","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n de Oncolog\u00eda Hematolog\u00eda, UMAE, Hospital de Especialidades, Centro M\u00e9dico Nacional de Occidente, Instituto Mexicano del Seguro Social, 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6565-6962","authenticated-orcid":false,"given":"Daniel","family":"Sat-Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Departamento de Morfolog\u00eda, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdG), Cuerpo Acad\u00e9mico UDG CA-874 \u201cCiencias morfol\u00f3gicas en el diagn\u00f3stico y tratamiento de la enfermedad\u201d, 950 Sierra Mojada, Gate 7, Building C, 1st level, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"},{"name":"Departamento Cl\u00ednico de Oncolog\u00eda Quir\u00fargica, Divisi\u00f3n de Oncolog\u00eda Hematolog\u00eda, UMAE, Hospital de Especialidades, Centro M\u00e9dico Nacional de Occidente, Instituto Mexicano del Seguro Social, 1000 Belisario Dom\u00ednguez, Colonia Independencia, Guadalajara, Jalisco 44340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,7,16]]},"reference":[{"key":"ref_1","first-page":"65","article-title":"Oncolog\u00eda en gastroenterolog\u00eda C\u00e1ncer de colon. 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