{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T11:52:23Z","timestamp":1778586743397,"version":"3.51.4"},"reference-count":41,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T00:00:00Z","timestamp":1604275200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1138533"],"award-info":[{"award-number":["1138533"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Danone Research","award":["No Number"],"award-info":[{"award-number":["No Number"]}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","award":["No number"],"award-info":[{"award-number":["No number"]}],"id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"name":"PKD Australia","award":["No Number"],"award-info":[{"award-number":["No Number"]}]},{"name":"Westmead Medical Research Foundation","award":["No  Number"],"award-info":[{"award-number":["No  Number"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The excess intake of dietary sodium is a key modifiable factor for reducing disease progression in autosomal dominant polycystic kidney disease (ADPKD). The aim of this study was to test the hypothesis that the scored salt questionnaire (SSQ; a frequency questionnaire of nine sodium-rich food types) is a valid instrument to identify high dietary salt intake in ADPKD. The performance of the SSQ was evaluated in adults with ADPKD with an estimated glomerular filtration rate (eGFR) \u2265 30 mL\/min\/1.73 m2 during the screening visit of the PREVENT-ADPKD trial. High dietary sodium intake (HSI) was defined by a mean 24-h urinary sodium excretion \u2265 100 mmol\/day from two collections. The median 24-h urine sodium excretion was 132 mmol\/day (IQR: 112\u2013172 mmol\/d) (n = 75; mean age: 44.6 \u00b1 11.5 years old; 53% female), and HSI (86.7% of total) was associated with male gender and higher BMI and systolic blood pressure (p &lt; 0.05). The SSQ score (73 \u00b1 23; mean \u00b1 SD) was weakly correlated with log10 24-h urine sodium excretion (r = 0.29, p = 0.01). Receiving operating characteristic analysis showed that the optimal cut-off point in predicting HSI was an SSQ score of 74 (area under the curve 0.79; sensitivity 61.5%; specificity 90.0%; p &lt; 0.01). The evaluation of the SSQ in participants with a BMI \u2265 25 (n = 46) improved the sensitivity (100%) and the specificity (100%). Consumers with an SSQ score \u2265 74 (n = 41) had higher relative percentage intake of processed meats\/seafood and flavourings added to cooking (p &lt; 0.05). In conclusion, the SSQ is a valid tool for identifying high dietary salt intake in ADPKD but its value proposition (over 24-h urinary sodium measurement) is that it may provide consumers and their healthcare providers with insight into the potential origin of sodium-rich food sources.<\/jats:p>","DOI":"10.3390\/nu12113376","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T09:04:46Z","timestamp":1604307886000},"page":"3376","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Assessment of Dietary Sodium Intake Using the Scored Salt Questionnaire in Autosomal Dominant Polycystic Kidney Disease"],"prefix":"10.3390","volume":"12","author":[{"given":"Annette T. Y.","family":"Wong","sequence":"first","affiliation":[{"name":"Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney 2145, Australia"},{"name":"Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney 2145, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Munt","sequence":"additional","affiliation":[{"name":"Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney 2145, Australia"},{"name":"Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney 2145, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6478-1374","authenticated-orcid":false,"given":"Margaret","family":"Allman-Farinelli","sequence":"additional","affiliation":[{"name":"School of Life and Environmental Sciences, The University of Sydney, Sydney 2006, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil V.","family":"Badve","sequence":"additional","affiliation":[{"name":"St George Hospital, Sydney 2217, Australia"},{"name":"The George Institute for Global Health, University of New South Wales, Sydney 2042, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5884-640X","authenticated-orcid":false,"given":"Neil","family":"Boudville","sequence":"additional","affiliation":[{"name":"Sir Charles Gairdner Hospital, Perth 6009, Australia"},{"name":"Medical School, University of Western Australia, Perth 6009, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Coolican","sequence":"additional","affiliation":[{"name":"Polycystic Kidney Disease Australia, Roseville 2069, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley N.","family":"Chandra","sequence":"additional","affiliation":[{"name":"Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney 2145, Australia"},{"name":"Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney 2145, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Coulshed","sequence":"additional","affiliation":[{"name":"North Shore Nephrology, Sydney 2065, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mangalee","family":"Fernando","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Prince of Wales Hospital, Sydney 2031, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jared","family":"Grantham","sequence":"additional","affiliation":[{"name":"Kansas University Medical Center, Kansas City, MO 66103, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imad","family":"Haloob","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Bathurst Hospital, Bathurst 2795, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C. H.","family":"Harris","sequence":"additional","affiliation":[{"name":"Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney 2145, Australia"},{"name":"Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney 2145, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmel M.","family":"Hawley","sequence":"additional","affiliation":[{"name":"Australasian Kidney Trials Network, University of Queensland at Princess Alexandra Hospital, Brisbane 4102, Australia"},{"name":"Translational Research Institute, Brisbane 4102, Australia"},{"name":"Department of Nephrology, Princess Alexandra Hospital, Brisbane 4102, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Holt","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Wollongong Hospital, Wollongong 2500, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5491-3460","authenticated-orcid":false,"given":"David W.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Australasian Kidney Trials Network, University of Queensland at Princess Alexandra Hospital, Brisbane 4102, Australia"},{"name":"Translational Research Institute, Brisbane 4102, Australia"},{"name":"Department of Nephrology, Princess Alexandra Hospital, Brisbane 4102, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karthik","family":"Kumar","sequence":"additional","affiliation":[{"name":"Gosford Nephrology, Gosford 2250, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9400-3696","authenticated-orcid":false,"given":"Vincent W.","family":"Lee","sequence":"additional","affiliation":[{"name":"Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney 2145, Australia"},{"name":"Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney 2145, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen","family":"Lonergan","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Wollongong Hospital, Wollongong 2500, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Mai","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Liverpool Hospital, Southwestern Sydney Local Health District, Sydney 2170, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1815-844X","authenticated-orcid":false,"given":"Anna","family":"Rangan","sequence":"additional","affiliation":[{"name":"School of Life and Environmental Sciences, The University of Sydney, Sydney 2006, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon D.","family":"Roger","sequence":"additional","affiliation":[{"name":"Renal Research, Gosford 2250, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayanthooran","family":"Saravanabavan","sequence":"additional","affiliation":[{"name":"Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney 2145, Australia"},{"name":"Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney 2145, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7648-007X","authenticated-orcid":false,"given":"Kamal","family":"Sud","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Nepean Hospital, Sydney 2751, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicente E.","family":"Torres","sequence":"additional","affiliation":[{"name":"Translational Polycystic Kidney Disease Center, Mayo Clinic, Rochester, NY 55902, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eswari","family":"Vilayur","sequence":"additional","affiliation":[{"name":"Department of Nephrology, John Hunter Hospital, Newcastle 2305, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3269-3801","authenticated-orcid":false,"given":"Jennifer Q. 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