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Low selenium intake during pregnancy has been associated with low birth weight and an increased risk of children being born small for gestational age (SGA). Based on data from the Norwegian Mother, Father and Child Cohort Study (MoBa) and the Medical Birth Registry of Norway (MBRN), we studied the association of maternal selenium intake from diet and supplements during the first half of pregnancy (n = 71,728 women) and selenium status in mid-pregnancy (n = 2628 women) with birth weight and SGA status, according to population-based, ultrasound-based and customized growth standards. An increase of one standard deviation of maternal dietary selenium intake was associated with increased birth weight z-scores (\u00df = 0.027, 95% CI: 0.007, 0.041) and lower SGA risk (OR = 0.91, 95% CI 0.86, 0.97) after adjusting for confounders. Maternal organic and inorganic selenium intake from supplements as well as whole blood selenium concentration were not associated with birth weight or SGA. Our results suggest that a maternal diet rich in selenium during pregnancy may be beneficial for foetal growth. However, the effect estimates were small and further studies are needed to elucidate the potential impact of selenium on foetal growth.<\/jats:p>","DOI":"10.3390\/nu13010023","type":"journal-article","created":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T08:38:43Z","timestamp":1608712723000},"page":"23","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Maternal Dietary Selenium Intake during Pregnancy Is Associated with Higher Birth Weight and Lower Risk of Small for Gestational Age Births in the Norwegian Mother, Father and Child Cohort Study"],"prefix":"10.3390","volume":"13","author":[{"given":"Pol","family":"Sol\u00e9-Navais","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6315-7134","authenticated-orcid":false,"given":"Anne Lise","family":"Brants\u00e6ter","sequence":"additional","affiliation":[{"name":"Division of Infection Control, Environment and Health, Norwegian Institute of Public Health, 0213 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2591-8435","authenticated-orcid":false,"given":"Ida Henriette","family":"Caspersen","sequence":"additional","affiliation":[{"name":"Centre for Fertility and Health, Norwegian Institute of Public Health, 0403 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Lundh","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University, 221 85 Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis J.","family":"Muglia","sequence":"additional","affiliation":[{"name":"Cincinnati Children\u2019s Hospital Medical Center, Division of Human Genetics and Perinatal Institute, Cincinnati, OH 45229, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA"},{"name":"Office of the President, Burroughs Wellcome Fund, Research Triangle Park, Durham, NC 27709, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3591-7017","authenticated-orcid":false,"given":"Helle Margrete","family":"Meltzer","sequence":"additional","affiliation":[{"name":"Division of Infection Control, Environment and Health, Norwegian Institute of Public Health, 0213 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge","family":"Zhang","sequence":"additional","affiliation":[{"name":"Cincinnati Children\u2019s Hospital Medical Center, Division of Human Genetics and Perinatal Institute, Cincinnati, OH 45229, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5079-2374","authenticated-orcid":false,"given":"Bo","family":"Jacobsson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden"},{"name":"Department of Genetics and Bioinformatics, Domain of Health Data and Digitalisation, Institute of Public Health, 0456 Oslo, Norway"},{"name":"Department of Obstetrics and Gynaecology, Sahlgrenska University Hospital\/\u00d6stra, 405 30 Gothenburg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Sengpiel","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden"},{"name":"Department of Obstetrics and Gynaecology, Sahlgrenska University Hospital\/\u00d6stra, 405 30 Gothenburg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5317-2768","authenticated-orcid":false,"given":"Malin","family":"Barman","sequence":"additional","affiliation":[{"name":"Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden"},{"name":"Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,12,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Bukowski, R., Hansen, N.I., Willinger, M., Reddy, U.M., Parker, C.B., Pinar, H., Silver, R.M., Dudley, N.J., Stoll, B.J., and Saade, G.R. 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