{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T14:17:17Z","timestamp":1784902637441,"version":"3.55.0"},"reference-count":57,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T00:00:00Z","timestamp":1609891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Regional Government of Andalusia. Excellence Research Project","award":["P12-AGR-2581"],"award-info":[{"award-number":["P12-AGR-2581"]}]},{"DOI":"10.13039\/501100006393","name":"University of Granada","doi-asserted-by":"publisher","award":["PP2017-PIP14"],"award-info":[{"award-number":["PP2017-PIP14"]}],"id":[{"id":"10.13039\/501100006393","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Spanish Ministry of Education, Culture and Sports","award":["FPU17\/03715"],"award-info":[{"award-number":["FPU17\/03715"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The current study was designed to assess the influence of consumption of ultra-processed (UPF) on oxidative\/antioxidant balance and evoked inflammatory signaling in young patients with celiac disease (CD). The study included 85 children. The celiac group (n = 53) included children with CD with a long (&gt;18 months, n = 17) or recent (&lt;18 months, n = 36) adherence to a gluten-free diet (GFD). The control group (n = 32) included healthy children with a significantly lower consumption of UPF compared to the CD group, both expressed as kcal\/day (p = 0.043) and as percentage of daily energy intake (p = 0.023). Among children with CD, the group with the lowest consumption of UPF (below the 50% of daily energy intake) had a greater Mediterranean diet (MD) adherence and higher moderate physical activity levels. In addition, CD children with the lowest consumption of UPF had healthier redox (lower soluble superoxide dismutase-1 and 15-F2t-isoprostanes) and inflammatory profiles (lower macrophage inflammatory protein-1\u03b1) compared to the group with the highest consumption of UPF (all, p &lt; 0.05) regardless of the time on a GFD. These findings highlight the importance of a correct monitoring of the GFD. An unbalanced GFD with high consumption of UPF and an unhealthy pattern with less physical activity and worse adherence to MD results in a worse inflammatory profile, which could act as a parallel pathway that could have important consequences on the pathophysiology of the disease.<\/jats:p>","DOI":"10.3390\/nu13010156","type":"journal-article","created":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T09:15:16Z","timestamp":1609924516000},"page":"156","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Influence of Ultra-Processed Foods Consumption on Redox Status and Inflammatory Signaling in Young Celiac Patients"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9573-3244","authenticated-orcid":false,"given":"Teresa","family":"Nestares","sequence":"first","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 Mataix Verd\u00fa\u201d (INYTA), Biomedical Research Centre (CIBM), University of Granada, 18100 Armilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0113-9904","authenticated-orcid":false,"given":"Rafael","family":"Mart\u00edn-Masot","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, 19010 M\u00e1laga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Flor-Alemany","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 Mataix Verd\u00fa\u201d (INYTA), Biomedical Research Centre (CIBM), University of Granada, 18100 Armilla, Spain"},{"name":"Sport and Health University Research Centre (iMUDS), University of Granada, 18100 Armilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonela","family":"Bonavita","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Granada, 18071 Granada, Spain"},{"name":"Biohealth Research Institute, 18071 Granada, Spain"},{"name":"Maternal and Child Health Network, Carlos III Health Institute, 28029 Madrid, Spain"},{"name":"Pediatric Clinical Management Unit, \u201cVirgen de las Nieves\u201d University Hospital, 18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2867-378X","authenticated-orcid":false,"given":"Virginia A.","family":"Aparicio","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, University of Granada, 18071 Granada, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 Mataix Verd\u00fa\u201d (INYTA), Biomedical Research Centre (CIBM), University of Granada, 18100 Armilla, Spain"},{"name":"Sport and Health University Research Centre (iMUDS), University of Granada, 18100 Armilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"507","DOI":"10.14309\/ajg.0000000000000523","article-title":"Incidence of Celiac Disease Is Increasing over Time: A Systematic Review and Meta-analysis","volume":"115","author":"King","year":"2020","journal-title":"Am. 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