{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T07:08:05Z","timestamp":1779260885024,"version":"3.51.4"},"reference-count":93,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T00:00:00Z","timestamp":1614297600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>This study investigated the effect of decaffeinated green tea extract (dGTE), with or without antioxidant nutrients, on fat oxidation, body composition and cardio-metabolic health measures in overweight individuals engaged in regular exercise. Twenty-seven participants (20 females, 7 males; body mass: 77.5 \u00b1 10.5 kg; body mass index: 27.4 \u00b1 3.0 kg\u00b7m2; peak oxygen uptake (V.O2peak): 30.2 \u00b1 5.8 mL\u00b7kg\u22121\u00b7min\u22121) were randomly assigned, in a double-blinded manner, either: dGTE (400 mg\u00b7d\u22121 (\u2212)-epigallocatechin\u22123-gallate (EGCG), n = 9); a novel dGTE+ (400 mg\u00b7d\u22121 EGCG, quercetin (50 mg\u00b7d\u22121) and \u03b1-lipoic acid (LA, 150 mg\u00b7d\u22121), n = 9); or placebo (PL, n = 9) for 8 weeks, whilst maintaining standardised, aerobic exercise. Fat oxidation (\u2018FATMAX\u2019 and steady state exercise protocols), body composition, cardio-metabolic and blood measures (serum glucose, insulin, leptin, adiponectin, glycerol, free fatty acids, total cholesterol, high [HDL-c] and low-density lipoprotein cholesterol [LDL-c], triglycerides, liver enzymes and bilirubin) were assessed at baseline, week 4 and 8. Following 8 weeks of dGTE+, maximal fat oxidation (MFO) significantly improved from 154.4 \u00b1 20.6 to 224.6 \u00b1 23.2 mg\u00b7min\u22121 (p = 0.009), along with a 22.5% increase in the exercise intensity at which fat oxidation was deemed negligible (FATMIN; 67.6 \u00b1 3.6% V.O2peak, p = 0.003). Steady state exercise substrate utilisation also improved for dGTE+ only, with respiratory exchange ratio reducing from 0.94 \u00b1 0.01 at week 4, to 0.89 \u00b1 0.01 at week 8 (p = 0.004). This corresponded with a significant increase in the contribution of fat to energy expenditure for dGTE+ from 21.0 \u00b1 4.1% at week 4, to 34.6 \u00b1 4.7% at week 8 (p = 0.006). LDL-c was also lower (normalised fold change of \u22120.09 \u00b1 0.06) for dGTE+ by week 8 (p = 0.038). No other significant effects were found in any group. Eight weeks of dGTE+ improved MFO and substrate utilisation during exercise, and lowered LDL-c. However, body composition and cardio-metabolic markers in healthy, overweight individuals who maintained regular physical activity were largely unaffected by dGTE.<\/jats:p>","DOI":"10.3390\/nu13030764","type":"journal-article","created":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T09:47:20Z","timestamp":1614332840000},"page":"764","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["The Impact of Decaffeinated Green Tea Extract on Fat Oxidation, Body Composition and Cardio-Metabolic Health in Overweight, Recreationally Active Individuals"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3169-2041","authenticated-orcid":false,"given":"Justin D.","family":"Roberts","sequence":"first","affiliation":[{"name":"Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport Science, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley G. B.","family":"Willmott","sequence":"additional","affiliation":[{"name":"Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport Science, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liam","family":"Beasley","sequence":"additional","affiliation":[{"name":"Department for Health, University of Bath, Bath BA2 7AY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariette","family":"Boal","sequence":"additional","affiliation":[{"name":"Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport Science, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rory","family":"Davies","sequence":"additional","affiliation":[{"name":"Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport Science, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence","family":"Martin","sequence":"additional","affiliation":[{"name":"Cambridge Centre for Sport and Exercise Sciences, School of Psychology and Sport Science, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8549-7583","authenticated-orcid":false,"given":"Havovi","family":"Chichger","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0409-4724","authenticated-orcid":false,"given":"Lata","family":"Gautam","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5785-984X","authenticated-orcid":false,"given":"Juan","family":"Del Coso","sequence":"additional","affiliation":[{"name":"Centre for Sport Studies, Rey Juan Carlos University, 28943, Fuenlabrada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1093\/ajcn\/80.6.1558","article-title":"Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement","volume":"80","author":"Henning","year":"2004","journal-title":"Am. 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