{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T19:15:28Z","timestamp":1790795728219,"version":"4.1.0"},"reference-count":286,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Diet plays a pivotal role in the onset and course of inflammatory bowel disease (IBD). Patients are keen to know what to eat to reduce symptoms and flares, but dietary guidelines are lacking. To advice patients, an overview of the current evidence on food (group) level is needed. This narrative review studies the effects of food (groups) on the onset and course of IBD and if not available the effects in healthy subjects or animal and in vitro IBD models. Based on this evidence the Groningen anti-inflammatory diet (GrAID) was designed and compared on food (group) level to other existing IBD diets. Although on several foods conflicting results were found, this review provides patients a good overview. Based on this evidence, the GrAID consists of lean meat, eggs, fish, plain dairy (such as milk, yoghurt, kefir and hard cheeses), fruit, vegetables, legumes, wheat, coffee, tea and honey. Red meat, other dairy products and sugar should be limited. Canned and processed foods, alcohol and sweetened beverages should be avoided. This comprehensive review focuses on anti-inflammatory properties of foods providing IBD patients with the best evidence on which foods they should eat or avoid to reduce flares. This was used to design the GrAID.<\/jats:p>","DOI":"10.3390\/nu13041067","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T14:51:12Z","timestamp":1616683872000},"page":"1067","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":110,"title":["Food and Food Groups in Inflammatory Bowel Disease (IBD): The Design of the Groningen Anti-Inflammatory Diet (GrAID)"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8111-6026","authenticated-orcid":false,"given":"Marjo J. E.","family":"Campmans-Kuijpers","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4563-7462","authenticated-orcid":false,"given":"Gerard","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/nrgastro.2017.136","article-title":"Environmental triggers in IBD: A review of progress and evidence","volume":"15","author":"Ananthakrishnan","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/nrgastro.2015.150","article-title":"The global burden of IBD: From 2015 to 2025","volume":"12","author":"Kaplan","year":"2015","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1002\/mnfr.201100630","article-title":"Role of nutrition and microbiota in susceptibility to inflammatory bowel diseases","volume":"56","author":"Gentschew","year":"2012","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/nature12820","article-title":"Diet rapidly and reproducibly alters the human gut microbiome","volume":"505","author":"David","year":"2014","journal-title":"Nature"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/MCO.0000000000000402","article-title":"Exclusive enteral nutrition for inducing remission in inflammatory bowel disease in paediatric patients","volume":"20","author":"Assa","year":"2017","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.crohns.2014.04.005","article-title":"Consensus guidelines of ECCO\/ESPGHAN on the medical management of pediatric Crohn\u2019s disease","volume":"8","author":"Ruemmele","year":"2014","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.3748\/wjg.v16.i20.2484","article-title":"Lifestyle-related disease in Crohn\u2019s disease: Relapse prevention by a semi-vegetarian diet","volume":"16","author":"Chiba","year":"2010","journal-title":"World J. Gastroenterol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2891-13-5","article-title":"An anti-inflammatory diet as treatment for inflammatory bowel disease: A case series report","volume":"13","author":"Olendzki","year":"2014","journal-title":"Nutr. J."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/MPG.0000000000000103","article-title":"Nutritional therapy in pediatric Crohn disease: The specific carbohydrate diet","volume":"58","author":"Suskind","year":"2014","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Suskind, D.L., Lee, D., Kim, Y.M., Wahbeh, G., Singh, N., Braly, K., Nuding, M., Nicora, C.D., Purvine, S.O., and Lipton, M.S. (2020). The specific carbohydrate diet and diet modification as induction therapy for pediatric crohn\u2019s disease: A randomized diet controlled trial. Nutrients, 12.","DOI":"10.3390\/nu12123749"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1093\/ecco-jcc\/jjx071","article-title":"Dietary therapy with the Crohn\u2019s disease exclusion diet is a successful strategy for induction of Remission in children and adults failing biological therapy","volume":"11","author":"Boneh","year":"2017","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1053\/j.gastro.2019.04.021","article-title":"Crohn\u2019s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial","volume":"157","author":"Levine","year":"2019","journal-title":"Gastroenterology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1053\/j.gastro.2018.12.002","article-title":"Treatment of Active Crohn\u2019s Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition","volume":"156","author":"Svolos","year":"2019","journal-title":"Gastroenterology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1053\/j.gastro.2019.09.024","article-title":"Effects of Low FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial","volume":"158","author":"Cox","year":"2020","journal-title":"Gastroenterology"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Grammatikopoulou, M.G., Goulis, D.G., Gkiouras, K., Nigdelis, M.P., Papageorgiou, S.T., Papamitsou, T., Forbes, A., and Bogdanos, D.P. (2020). Low fodmap diet for functional gastrointestinal symptoms in quiescent inflammatory bowel disease: A systematic review of randomized controlled trials. Nutrients, 12.","DOI":"10.3390\/nu12123648"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1053\/j.gastro.2015.01.007","article-title":"Diet in the Pathogenesis and Treatment of Inflammatory Bowel Diseases","volume":"148","author":"Lee","year":"2015","journal-title":"Gastroenterology"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1053\/j.gastro.2004.01.063","article-title":"V Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences","volume":"126","author":"Loftus","year":"2004","journal-title":"Gastroenterology"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3109\/00365528708991479","article-title":"Crohn\u2019s Disease an Ulcerative Colitis\u2014A Review of Dietary Studies with Emphasis on Methodologic Aspects","volume":"22","author":"Persson","year":"1987","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.crohns.2011.05.010","article-title":"Environmental factors in inflammatory bowel disease: A case-control study based on a Danish inception cohort","volume":"5","author":"Hansen","year":"2011","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.crohns.2013.01.004","article-title":"Hypothesis: Increased consumption of emulsifiers as an explanation for the rising incidence of Crohn\u2019s disease","volume":"7","author":"Roberts","year":"2013","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Christ, A., and Latz, E. (2019). The Western lifestyle has lasting effects on metaflammation. Nat. Rev. Immunol.","DOI":"10.1038\/s41577-019-0156-1"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/ibd.22965","article-title":"Dietary beliefs and behavior among inflammatory bowel disease patients","volume":"19","author":"Zallot","year":"2013","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1007\/s10620-012-2373-3","article-title":"Dietary Patterns and Self-Reported Associations of Diet with Symptoms of Inflammatory Bowel Disease","volume":"58","author":"Cohen","year":"2013","journal-title":"Dig. Dis. Sci."},{"key":"ref_24","first-page":"33","article-title":"Nutrition issues in gastroenterology, series #5. Nutritional Considerations in IBD","volume":"27","author":"Eiden","year":"2003","journal-title":"Pract. Gastroenterol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1177\/0148607107031004311","article-title":"Nutrition Assessment of Patients with Inflammatory Bowel Disease","volume":"31","author":"Vagianos","year":"2007","journal-title":"J. Parenter. Enter. Nutr."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1177\/0148607114549254","article-title":"What are adults with inflammatory bowel disease (IBD) eating? A closer look at the dietary habits of a population-based Canadian IBD cohort","volume":"40","author":"Vagianos","year":"2016","journal-title":"J. Parenter. Enter. Nutr."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3945\/ajcn.2009.27725","article-title":"Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease","volume":"91","author":"Sun","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"398","DOI":"10.7326\/M13-1788","article-title":"Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk: A Systematic Review and Meta-analysis","volume":"160","author":"Chowdhury","year":"2014","journal-title":"Ann. Intern. Med."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Zheng, Y., Li, Y., Satija, A., Pan, A., Sotos-Prieto, M., Rimm, E., Willett, W.C., and Hu, F.B. (2019). Association of changes in red meat consumption with total and cause specific mortality among US women and men: Two prospective cohort studies. BMJ, 365.","DOI":"10.1136\/bmj.l2110"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.cgh.2016.12.036","article-title":"High Dietary Intake of Specific Fatty Acids Increases Risk of Flares in Patients with Ulcerative Colitis in Remission during Treatment with Aminosalicylates","volume":"15","author":"Barnes","year":"2017","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/apt.13456","article-title":"Review article: Insights into colonic protein fermentation, its modulation and potential health implications","volume":"43","author":"Yao","year":"2016","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1038\/ajg.2010.192","article-title":"Animal Protein Intake and Risk of Inflammatory Bowel Disease: The E3N Prospective Study","volume":"105","author":"Jantchou","year":"2010","journal-title":"Am. J. Gastroenterol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1007\/s10620-017-4620-0","article-title":"Influence of Diet on the Course of Inflammatory Bowel Disease","volume":"62","author":"Tasson","year":"2017","journal-title":"Dig. Dis. Sci."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1017\/S0029665116000100","article-title":"Socioeconomic and demographic drivers of red and processed meat consumption: Implications for health and environmental sustainability","volume":"75","author":"Clonan","year":"2016","journal-title":"Proc. Nutr. Soc."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1053\/j.gastro.2019.03.015","article-title":"A Diet Low in Red and Processed Meat Does Not Reduce Rate of Crohn\u2019s Disease Flares","volume":"157","author":"Albenberg","year":"2019","journal-title":"Gastroenterology"},{"key":"ref_36","unstructured":"Peters, V. (2021). Western and carnivorous dietary patterns are associated with greater likelihood of inflammatory bowel disease in a large prospective population-based cohort. Towards Dietary Assessment and Interventions for Patients with Inflammatory Bowel Disease, Ridderprint BV."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1136\/gut.2003.024828","article-title":"Influence of dietary factors on the clinical course of ulcerative colitis: A prospective cohort study","volume":"53","author":"Jowett","year":"2004","journal-title":"Gut"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Levine, A., El-Matary, W., and Van Limbergen, J. (2020). A case-based approach to new directions in dietary therapy of crohn\u2019s disease: Food for thought. Nutrients, 12.","DOI":"10.3390\/nu12030880"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/ejcn.2011.141","article-title":"A vegan or vegetarian diet substantially alters the human colonic faecal microbiota","volume":"66","author":"Zimmer","year":"2012","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.pharmthera.2013.10.010","article-title":"Pharmacology and therapeutics of omega-3 polyunsaturated fatty acids in chronic inflammatory disease","volume":"141","author":"Yates","year":"2014","journal-title":"Pharmacol. Ther."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/ajg.2011.44","article-title":"Dietary intake and risk of developing inflammatory bowel disease: A systematic review of the literature","volume":"106","author":"Hou","year":"2011","journal-title":"Am. J. Gastroenterol."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Scaioli, E., Liverani, E., and Belluzzi, A. (2017). The Imbalance between n-6\/n-3 Polyunsaturated Fatty Acids and Inflammatory Bowel Disease: A Comprehensive Review and Future Therapeutic Perspectives. Int. J. Mol. Sci., 18.","DOI":"10.3390\/ijms18122619"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Morampudi, V., Bhinder, G., Wu, X., Dai, C., Sham, H.P., Vallance, B.A., and Jacobson, K. (2014). DNBS\/TNBS colitis models: Providing insights into inflammatory bowel disease and effects of dietary fat. J. Vis. Exp., 1\u20138.","DOI":"10.3791\/51297"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Declercq, V., Langille, M.G.I., and Van Limbergen, J. (2018). Differences in adiposity and diet quality among individuals with inflammatory bowel disease in Eastern Canada. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0200580"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Young, D., Ibuki, M., Nakamori, T., Fan, M., and Mine, Y. (2012). Soy-derived di-and tripeptides alleviate colon and ileum inflammation in pigs with dextran sodium sulfate-induced colitis. J. Nutr.","DOI":"10.3945\/jn.111.149104"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1016\/j.bbagen.2012.07.007","article-title":"The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation","volume":"1820","author":"Zhang","year":"2012","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Raffner Basson, A., Gomez-Nguyen, A., LaSalla, A., Butt\u00f3, L., Kulpins, D., Warner, A., Di Martino, L., Ponzani, G., Osme, A., and Rodriguez-Palacios, A. (2021). Replacing Animal Protein with Soy-Pea Protein in an \u201cAmerican Diet\u201d Controls Murine Crohn Disease\u2013Like Ileitis Regardless of Firmicutes: Bacteroidetes Ratio. J. Nutr.","DOI":"10.1093\/jn\/nxaa386"},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Wang, G., Ren, J., Li, G., Hu, Q., Gu, G., Ren, H., Hong, Z., and Li, J. (2017). The utility of food antigen test in the diagnosis of Crohn\u2019s disease and remission maintenance after exclusive enteral nutrition. Clin. Res. Hepatol. Gastroenterol.","DOI":"10.1016\/j.clinre.2017.09.002"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/j.1463-1318.2010.02373.x","article-title":"Food-specific IgG4-guided exclusion diets improve symptoms in Crohn\u2019s disease: A pilot study","volume":"13","author":"Rajendran","year":"2011","journal-title":"Color. Dis."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"6444","DOI":"10.1039\/C8FO01939H","article-title":"The anti-inflammatory activity of peptides from simulated gastrointestinal digestion of preserved egg white in DSS-induced mouse colitis","volume":"9","author":"Zhang","year":"2018","journal-title":"Food Funct."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"3814","DOI":"10.3748\/wjg.v18.i29.3814","article-title":"Impact of environmental and dietary factors on the course of inflammatory bowel disease","volume":"18","year":"2012","journal-title":"World J. Gastroenterol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S2468-1253(18)30392-3","article-title":"Fermented foods: Fad or favourable addition to the diet?","volume":"4","author":"Staudacher","year":"2019","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/jgh.13695","article-title":"Use of the low-FODMAP diet in inflammatory bowel disease","volume":"32","author":"Gibson","year":"2017","journal-title":"J. Gastroenterol. Hepatol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.mrfmmm.2010.01.020","article-title":"Dietary factors in chronic inflammation: Food tolerances and intolerances of a New Zealand Caucasian Crohn\u2019s disease population","volume":"690","author":"Triggs","year":"2010","journal-title":"Mutat. Res. Fundam. Mol. Mech. Mutagen."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1080\/00365521.2017.1397736","article-title":"Persistent symptoms in patients with Crohn\u2019s disease in remission: An exploratory study on the role of diet","volume":"53","author":"Sommer","year":"2018","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/j.1365-2249.2007.03434.x","article-title":"Anti-inflammatory effects of probiotic yogurt in inflammatory bowel disease patients","volume":"149","author":"Kirjavainen","year":"2007","journal-title":"Clin. Exp. Immunol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1002\/mnfr.201500580","article-title":"Combining selected immunomodulatory Propionibacterium freudenreichii and Lactobacillus delbrueckii strains: Reverse engineering development of an anti-inflammatory cheese","volume":"60","author":"Breton","year":"2016","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.intimp.2015.04.004","article-title":"Anti-inflammatory properties of fermented soy milk with Lactococcus lactis subsp. lactis S-SU2 in murine macrophage RAW264.7 cells and DSS-induced IBD model mice","volume":"26","author":"Kawahara","year":"2015","journal-title":"Int. Immunopharmacol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"242","DOI":"10.5152\/tjg.2018.18227","article-title":"Effect of administering kefir on the changes in fecal microbiota and symptoms of inflammatory bowel disease: A randomized controlled trial","volume":"30","author":"Yilmaz","year":"2020","journal-title":"Turkish J. Gastroenterol."},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Bekar, O., Yilmaz, Y., and Gulten, M. (2011). Kefir improves the efficacy and tolerability of triple therapy in eradicating Helicobacter pylori. J. Med. Food.","DOI":"10.1089\/jmf.2010.0099"},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Rabah, H., do Carmo, F.L.R., Carvalho, R.D.d.O., Cordeiro, B.F., da Silva, S.H., Oliveira, E.R., Lemos, L., Cara, D.C., Faria, A.M.C., and Garric, G. (2020). Beneficial Propionibacteria within a Probiotic Emmental Cheese: Impact on Dextran Sodium Sulphate-Induced Colitis in Mice. Microorganisms, 8.","DOI":"10.3390\/microorganisms8030380"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Tenore, G., Pagano, E., Lama, S., Vanacore, D., Di Maro, S., Maisto, M., Capasso, R., Merlino, F., Borrelli, F., and Stiuso, P. (2019). Intestinal Anti-Inflammatory Effect of a Peptide Derived from Gastrointestinal Digestion of Buffalo (Bubalus bubalis) Mozzarella Cheese. Nutrients, 11.","DOI":"10.3390\/nu11030610"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Kumar, N., and Goel, N. (2019). Phenolic acids: Natural versatile molecules with promising therapeutic applications. Biotechnol. Rep., 24.","DOI":"10.1016\/j.btre.2019.e00370"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1093\/ajcn\/79.5.727","article-title":"Polyphenols\u2014Food Sources and Bioavailability.pdf","volume":"79","author":"Manach","year":"2004","journal-title":"Am. J. Clin. Nutr"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jnutbio.2016.02.006","article-title":"Raspberry seed flour attenuates high-sucrose diet-mediated hepatic stress and adipose tissue inflammation","volume":"32","author":"Kang","year":"2016","journal-title":"J. Nutr. Biochem."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.3109\/00365528708991950","article-title":"Childhood Factors in Ulcerative Colitis and Crohn\u2019s Disease: An International Cooperative Study","volume":"22","author":"Gilat","year":"1987","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Halfvarson, J., Jess, T., Magnuson, A., Montgomery, S.M., Orholm, M., Tysk, C., Binder, V., J\u00e4rnerot, G., and J\u00e4rnerot, G. (2006). Environmental factors in inflammatory bowel disease: A co-twin control study of a Swedish-Danish twin population. Inflamm. Bowel Dis.","DOI":"10.1097\/01.mib.0000228998.29466.ac"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1111\/j.1572-0241.2007.01411.x","article-title":"Imbalances in Dietary Consumption of Fatty Acids, Vegetables, and Fruits Are Associated with Risk for Crohn\u2019s Disease in Children","volume":"102","author":"Amre","year":"2007","journal-title":"Am. J. Gastroenterol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1053\/j.gastro.2013.07.050","article-title":"A prospective study of long-term intake of dietary fiber and risk of Crohn\u2019s disease and ulcerative colitis","volume":"145","author":"Ananthakrishnan","year":"2013","journal-title":"Gastroenterology"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Ananthakrishnan, A.N., Khalili, H., Song, M., Higuchi, L.M., Richter, J.M., Nimptsch, K., Wu, K., and Chan, A.T. (2015). High School Diet and Risk of Crohn\u2019s Disease and Ulcerative Colitis. Inflamm. Bowel Dis., 1.","DOI":"10.1097\/MIB.0000000000000501"},{"key":"ref_71","unstructured":"Milajerdi, A., Ebrahimi-Daryani, N., Dieleman, L.A., Larijani, B., and Esmaillzadeh, A. (2020). Association of Dietary Fiber, Fruit, and Vegetable Consumption with Risk of Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. Adv. Nutr., 1\u20139."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00042737-199803000-00010","article-title":"Modern life\u2019 in the epidemiology of inflammatory bowel disease: A case-control study with special emphasis on nutritional factors","volume":"10","author":"Russel","year":"1998","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.nutres.2020.01.002","article-title":"Mango (Mangifera indica L.) polyphenols reduce IL-8, GRO, and GM-SCF plasma levels and increase Lactobacillus species in a pilot study in patients with inflammatory bowel disease","volume":"75","author":"Kim","year":"2020","journal-title":"Nutr. Res."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.intimp.2014.08.025","article-title":"Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-\u03baB and MAPK signaling inactivation","volume":"23","author":"Dou","year":"2014","journal-title":"Int. Immunopharmacol."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Lever, E., Scott, S.M., Louis, P., Emery, P.W., and Whelan, K. (2018). The effect of prunes on stool output, gut transit time and gastrointestinal microbiota: A randomised controlled trial. Clin. Nutr.","DOI":"10.1016\/j.clnu.2018.01.003"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1017\/S095442241700004X","article-title":"Dietary fibre in Europe: Current state of knowledge on definitions, sources, recommendations, intakes and relationships to health","volume":"30","author":"Stephen","year":"2017","journal-title":"Nutr. Res. Rev."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1017\/S0007114515003864","article-title":"Scientific evidence for health effects attributed to the consumption of probiotics and prebiotics: An update for current perspectives and future challenges","volume":"114","author":"Martinez","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1152\/physrev.2001.81.3.1031","article-title":"Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides","volume":"81","author":"Topping","year":"2001","journal-title":"Physiol. Rev."},{"key":"ref_79","first-page":"1","article-title":"Some Important Dietary Polyphenolic Compounds: An Anti-inflammatory and Immunoregulatory Perspective","volume":"17","author":"Kinger","year":"2017","journal-title":"Mini-Rev. Med. Chem."},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Higashi, A., Watanabe, Y., Ozasa, K., Yan, S., Hayashi, K., Aoike, A., Kawai, K., and Tada, M. (1991). A case-control study of ulcerative colitis. Jpn. J. Hyg.","DOI":"10.1265\/jjh.45.1035"},{"key":"ref_81","doi-asserted-by":"crossref","unstructured":"Reif, S., Klein, I., Lubin, F., Farbstein, M., Hallak, A., and Gilat, T. (1997). Pre-illness dietary factors in inflammatory bowel disease. Gut.","DOI":"10.1136\/gut.40.6.754"},{"key":"ref_82","doi-asserted-by":"crossref","unstructured":"Sakamoto, N., Kono, S., Wakai, K., Fukuda, Y., Satomi, M., Shimoyama, T., Inaba, Y., Miyake, Y., Sasaki, S., and Okamoto, K. (2005). Dietary risk factors for inflammatory bowel disease: A multicenter case-control study in Japan. Inflamm. Bowel Dis.","DOI":"10.1097\/00054725-200502000-00009"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1080\/10408399509527714","article-title":"On the presence of inulin and oligofructose as natural ingredients in the western diet","volume":"35","author":"Coussement","year":"1995","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/0016-5085(95)90192-2","article-title":"Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin","volume":"108","author":"Gibson","year":"1995","journal-title":"Gastroenterology"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.jff.2017.08.038","article-title":"Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner","volume":"37","author":"Hubbard","year":"2017","journal-title":"J. Funct. Foods"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"9277","DOI":"10.1021\/acs.jafc.9b03039","article-title":"3,3\u2032-Diindolylmethane Improves Intestinal Permeability Dysfunction in Cultured Human Intestinal Cells and the Model Animal Caenorhabditis elegans","volume":"67","author":"Kim","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"ref_87","first-page":"797","article-title":"Increased IgE-type antibody response to food allergens in irritable bowel syndrome and inflammatory bowel diseases","volume":"146","author":"Mekkel","year":"2005","journal-title":"Orvosi Hetilap"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1365-3083.2010.02477.x","article-title":"Effect of an extract based on the medicinal mushroom Agaricus blazei Murill on expression of cytokines and calprotectin in patients with ulcerative colitis and Crohn\u2019s disease","volume":"73","author":"Johnson","year":"2011","journal-title":"Scand. J. Immunol."},{"key":"ref_89","doi-asserted-by":"crossref","unstructured":"Nie, Y., Lin, Q., and Luo, F. (2017). Effects of Non-Starch Polysaccharides on Inflammatory Bowel Disease. Int. J. Mol. Sci., 18.","DOI":"10.3390\/ijms18071372"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3945\/ajcn.2009.27661","article-title":"Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: A systematic review","volume":"91","author":"Hunter","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1139\/g02-119","article-title":"The genetic basis of C-glycosyl flavone B-ring modification in maize (Zea mays L.) silks","volume":"46","author":"Snook","year":"2003","journal-title":"Genome"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s10725-013-9842-3","article-title":"Effects of shading on the photosynthetic capacity, endogenous hormones and root yield in purple-fleshed sweetpotato (Ipomoea batatas (L.) Lam)","volume":"72","author":"Wang","year":"2014","journal-title":"Plant. Growth Regul."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.carbpol.2015.06.045","article-title":"Characterization, antioxidant and antitumor activities of polysaccharides from purple sweet potato","volume":"132","author":"Wu","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"10773","DOI":"10.1021\/jf072256v","article-title":"Changes in Polyphenolic Content and Radical-Scavenging Activity of Sweetpotato (Ipomoea batatas L.) during Storage at Optimal and Low Temperatures","volume":"55","author":"Ishiguro","year":"2007","journal-title":"J. Agric. Food Chem."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.ijbiomac.2019.03.126","article-title":"Structural characterization and anti-inflammatory activity of alkali-soluble polysaccharides from purple sweet potato","volume":"131","author":"Chen","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.ijbiomac.2018.04.033","article-title":"Characterization, antioxidant activity and hepatoprotective effect of purple sweetpotato polysaccharides","volume":"115","author":"Sun","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1016\/j.cgh.2013.09.063","article-title":"Diet and Inflammatory Bowel Disease: Review of Patient- Targeted Recommendations","volume":"12","author":"Hou","year":"2015","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"100232","DOI":"10.1016\/j.bcdf.2020.100232","article-title":"Whole kidney bean (Phaseolus vulgaris) and bean hull reduce the total serum cholesterol, modulate the gut microbiota and affect the caecal fermentation in rats","volume":"24","author":"Kilua","year":"2020","journal-title":"Bioact. Carbohydrates Diet. Fibre"},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/00054725-200209000-00005","article-title":"Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease","volume":"8","author":"Patel","year":"2002","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"3078","DOI":"10.1007\/s10620-010-1158-9","article-title":"Naturally occurring glycoalkaloids in potatoes aggravate intestinal inflammation in two mouse models of inflammatory bowel disease","volume":"55","author":"Iablokov","year":"2010","journal-title":"Dig. Dis. Sci."},{"key":"ref_101","doi-asserted-by":"crossref","unstructured":"Zheng, Y., Wang, Q., Li, B., Lin, L., Tundis, R., Loizzo, M.R., Zheng, B., and Xiao, J. (2016). Characterization and prebiotic effect of the resistant starch from purple sweet potato. Molecules, 21.","DOI":"10.3390\/molecules21070932"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.3109\/09637486.2012.687366","article-title":"Wheat bran: Its composition and benefits to health, a European perspective","volume":"63","author":"Stevenson","year":"2012","journal-title":"Int. J. Food Sci. Nutr."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1136\/bmj.1.6126.1524","article-title":"Maintenance of remission in ulcerative colitis with sulphasalazine or a high-fibre diet: A clinical trial","volume":"1","author":"Davies","year":"1978","journal-title":"BMJ"},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Harris, P.J., and Ferguson, L.R. (1999). Dietary fibres may protect or enhance carcinogenesis. Mutat. Res. Genet. Toxicol. Environ. Mutagen.","DOI":"10.1016\/S1383-5742(99)00013-7"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/S0140-6736(03)13219-9","article-title":"The dietary fibre debate: More food for thought","volume":"361","author":"Ferguson","year":"2003","journal-title":"Lancet"},{"key":"ref_106","doi-asserted-by":"crossref","unstructured":"Ejderhamn, J., Hedenborg, G., and Strandvik, B. (1992). Long-term double-blind study on the influence of dietary fibres on faecal bile acid excretion in juvenile ulcerative colitis. Scand. J. Clin. Lab. Investig.","DOI":"10.3109\/00365519209115515"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1146\/annurev-food-030212-182554","article-title":"Impact of Diet on Human Intestinal Microbiota and Health","volume":"5","author":"Salonen","year":"2014","journal-title":"Annu. Rev. Food Sci. Technol."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/0016-5085(80)90432-1","article-title":"Gluten-sensitive diarrhea without evidence of celiac disease","volume":"79","author":"Cooper","year":"1980","journal-title":"Gastroenterology"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1053\/gast.2001.29572","article-title":"Celiac disease-like abnormalities in a subgroup of patients with irritable bowel syndrome","volume":"121","author":"Wahnschaffe","year":"2001","journal-title":"Gastroenterology"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1097\/MIB.0000000000000335","article-title":"A study evaluating the bidirectional relationship between inflammatory bowel disease and self-reported non-celiac gluten sensitivity","volume":"21","author":"Aziz","year":"2015","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_111","first-page":"1","article-title":"Prevalence and factors associated with gluten sensitivity in inflammatory bowel disease","volume":"5521","author":"Limketkai","year":"2017","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1097\/MIB.0000000000000077","article-title":"Prevalence of a gluten-free diet and improvement of clinical symptoms in patients with inflammatory bowel diseases","volume":"20","author":"Herfarth","year":"2014","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s13073-016-0295-y","article-title":"The influence of a short-term gluten-free diet on the human gut microbiome","volume":"8","author":"Bonder","year":"2016","journal-title":"Genome Med."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.1172\/JCI75436","article-title":"Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature","volume":"124","author":"Haberman","year":"2014","journal-title":"J. Clin. Investig."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.chom.2014.02.005","article-title":"The treatment-na\u00efve microbiome in new-onset Crohn\u2019s disease","volume":"15","author":"Gevers","year":"2015","journal-title":"Cell Host Microbe"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1097\/MIB.0b013e318281f573","article-title":"Semisynthetic diet ameliorates Crohn\u2019s disease-like ileitis in TNF\u0394ARE\/WTMice through antigen-independent mechanisms of gluten","volume":"19","author":"Wagner","year":"2013","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/j.1365-3083.2008.02104.x","article-title":"Dietary gluten reduces the number of intestinal regulatory T cells in mice","volume":"67","author":"Josephsen","year":"2008","journal-title":"Scand. J. Immunol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.3390\/nu7031565","article-title":"Effect of gliadin on permeability of intestinal biopsy explants from celiac disease patients and patients with non-celiac gluten sensitivity","volume":"7","author":"Hollon","year":"2015","journal-title":"Nutrients"},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Junker, Y., Zeissig, S., Kim, S.J., Barisani, D., Wieser, H., Leffler, D.A., Zevallos, V., Libermann, T.A., Dillon, S., and Freitag, T.L. (2012). Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4. J. Exp. Med.","DOI":"10.1084\/jem.20102660"},{"key":"ref_120","doi-asserted-by":"crossref","unstructured":"Zevallos, V.F., Raker, V., Tenzer, S., Jimenez-Calvente, C., Ashfaq-Khan, M., R\u00fcssel, N., Pickert, G., Schild, H., Steinbrink, K., and Schuppan, D. (2017). Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells. Gastroenterology.","DOI":"10.1053\/j.gastro.2016.12.006"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"S582","DOI":"10.1016\/S0016-5085(16)31994-1","article-title":"Nutritional wheat alpha-amylase\/trypsin inhibitors negatively affect intestinal microbiota and promote intestinal inflammation in mice","volume":"150","author":"Pickert","year":"2016","journal-title":"Gastroenterology"},{"key":"ref_122","first-page":"1","article-title":"Clinical and Fecal Microbial Changes With Diet Therapy in Active Inflammatory Bowel Disease","volume":"00","author":"Suskind","year":"2016","journal-title":"J. Clin. Gastroenterol."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/00054725-200303000-00005","article-title":"Increasing fecal butyrate in ulcerative colitis patients by diet: Controlled pilot study","volume":"9","author":"Hallert","year":"2003","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.jff.2014.12.019","article-title":"Antioxidative and anti-inflammatory effects of high beta-glucan concentration purified aqueous extract from oat in experimental model of LPS-induced chronic enteritis","volume":"14","author":"Suchecka","year":"2015","journal-title":"J. Funct. Foods"},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"3454","DOI":"10.1039\/C5FO00563A","article-title":"Oat \u03b2-glucan ameliorates dextran sulfate sodium (DSS)-induced ulcerative colitis in mice","volume":"6","author":"Liu","year":"2015","journal-title":"Food Funct."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1111\/j.1440-1746.2008.05681.x","article-title":"Is there a link between food and intestinal microbes and the occurrence of Crohn\u2019s disease and ulcerative colitis?","volume":"23","author":"Asakura","year":"2008","journal-title":"J. Gastroenterol. Hepatol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1348-0421.1989.tb01992.x","article-title":"Effect of Rice Fiber on Human Fecal Microflora","volume":"33","author":"Benno","year":"1989","journal-title":"Microbiol. Immunol."},{"key":"ref_128","doi-asserted-by":"crossref","unstructured":"Tang, Y., and Tsao, R. (2017). Phytochemicals in quinoa and amaranth grains and their antioxidant, anti-inflammatory, and potential health beneficial effects: A review. Mol. Nutr. Food Res., 61.","DOI":"10.1002\/mnfr.201600767"},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"14916","DOI":"10.1038\/s41598-018-33092-9","article-title":"Quinoa whole grain diet compromises the changes of gut microbiota and colonic colitis induced by dextran Sulfate sodium in C57BL\/6 mice","volume":"8","author":"Liu","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"164","DOI":"10.4236\/ojmm.2013.33025","article-title":"Phytochemical Profiling with Antioxidant and Antimicrobial Screening of Amaranthus viridis L. Leaf and Seed Extracts","volume":"3","author":"Ahmed","year":"2013","journal-title":"Open J. Med. Microbiol."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"3782","DOI":"10.1039\/C6FO00924G","article-title":"Assessment of the prebiotic effect of quinoa and amaranth in the human intestinal ecosystem","volume":"7","author":"Tavaria","year":"2016","journal-title":"Food Funct."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41430-018-0304-x","article-title":"Extra virgin olive oil: More than a healthy fat","volume":"72","year":"2019","journal-title":"Eur. J. Clin. Nutr."},{"key":"ref_133","doi-asserted-by":"crossref","unstructured":"Cariello, M., Contursi, A., Gadaleta, R.M., Piccinin, E., De Santis, S., Piglionica, M., Spaziante, A.F., Sabb\u00e0, C., Villani, G., and Moschetta, A. (2020). Extra-Virgin Olive Oil from Apulian Cultivars and Intestinal Inflammation. Nutrients, 12.","DOI":"10.3390\/nu12041084"},{"key":"ref_134","doi-asserted-by":"crossref","unstructured":"Morvaridi, M., Jafarirad, S., Seyedian, S.S., Alavinejad, P., and Cheraghian, B. (2020). The effects of extra virgin olive oil and canola oil on inflammatory markers and gastrointestinal symptoms in patients with ulcerative colitis. Eur. J. Clin. Nutr., 891\u2013899.","DOI":"10.1038\/s41430-019-0549-z"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1136\/gut.35.1_Suppl.S55","article-title":"Enteral nutrition as primary therapy in Crohn\u2019s disease","volume":"35","author":"Gassull","year":"1994","journal-title":"Gut"},{"key":"ref_136","doi-asserted-by":"crossref","unstructured":"Camuesco, D., G\u00e1lvez, J., Nieto, A., Comalada, M., Rodr\u00edguez-Cabezas, M.E., Concha, A., Xaus, J., and Zarzuelo, A. (2005). Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis. J. Nutr.","DOI":"10.1093\/jn\/135.4.687"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"S179","DOI":"10.1177\/01486071050290S4S179","article-title":"Macronutrients and bioactive molecules: Is there a specific role in the management of inflammatory bowel disease?","volume":"29","author":"Gassull","year":"2005","journal-title":"J. Parenter. Enter. Nutr."},{"key":"ref_138","doi-asserted-by":"crossref","unstructured":"Gassull, M.A., Fern\u00e1ndez-Ba\u00f1ares, F., Cabr\u00e9, E., Papo, M., Giaffer, M.H., S\u00e1nchez-Lombra\u00f1a, J.L., Richart, C., Malchow, H., Gonz\u00e1lez-Huix, F., and Esteve, M. (2002). Fat composition may be a clue to explain the primary therapeutic effect of enteral nutrition in Crohn\u2019s disease: Results of a double blind randomised multicentre European trial. Gut.","DOI":"10.1136\/gut.51.2.164"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.clnu.2010.03.003","article-title":"Extra-virgin olive oil-enriched diet modulates DSS-colitis-associated colon carcinogenesis in mice","volume":"29","author":"Villegas","year":"2010","journal-title":"Clin. Nutr."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1159\/000495516","article-title":"Dietary extra-virgin olive oil polyphenols do not attenuate colon inflammation in transgenic HLAB-27 rats but exert hypocholesterolemic effects through the modulation of HMGCR and PPAR-\u03b1 gene expression in the liver","volume":"11","author":"Bigagli","year":"2019","journal-title":"Lifestyle Genom."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.foodchem.2014.04.016","article-title":"The unsaponifiable fraction of extra virgin olive oil promotes apoptosis and attenuates activation and homing properties of T cells from patients with inflammatory bowel disease","volume":"161","author":"Magnusson","year":"2014","journal-title":"Food Chem."},{"key":"ref_142","first-page":"215","article-title":"Genetic possibilities for altering sunflower oil quality to obtain novel oils","volume":"86","year":"2008","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1743-7075-8-36","article-title":"Increasing dietary linoleic acid does not increase tissue arachidonic acid content in adults consuming Western-type diets: A systematic review","volume":"8","author":"Rett","year":"2011","journal-title":"Nutr. Metab."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1089\/jmf.2018.4323","article-title":"La Cottonseed oil protects against intestinal inflammation in dextran sodium sulfate-induced inflammatory bowel disease","volume":"22","author":"Park","year":"2019","journal-title":"J. Med. Food"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1136\/gut.47.3.397","article-title":"Butyrate inhibits inflammatory responses through NFB inhibition: Implications for Crohn\u2019s disease","volume":"47","author":"Segain","year":"2000","journal-title":"Gut"},{"key":"ref_146","doi-asserted-by":"crossref","unstructured":"Jamka, M., Kokot, M., Kaczmarek, N., Bermagambetova, S., Nowak, J.K., and Walkowiak, J. (2020). The Effect of Sodium Butyrate Enemas Compared with Placebo on Disease Activity, Endoscopic Scores, and Histological and Inflammatory Parameters in Inflammatory Bowel Diseases: A Systematic Review of Randomised Controlled Trials. Complement. Med. Res., 1\u201313.","DOI":"10.1159\/000512952"},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/nature11225","article-title":"Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10\u2212\/\u2212 mice","volume":"487","author":"Devkota","year":"2012","journal-title":"Nature"},{"key":"ref_148","doi-asserted-by":"crossref","unstructured":"Richman, E., and Rhodes, J.M. (2013). Alimentary Pharmacology and Therapeutics Review article: Evidence-based dietary advice for patients with inflammatory bowel disease. Aliment. Pharmacol. Ther.","DOI":"10.1111\/apt.12500"},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"4297","DOI":"10.3748\/wjg.v16.i34.4297","article-title":"Pre-illness changes in dietary habits and diet as a risk factor for inflammatory bowel disease: A case-control study","volume":"16","author":"Maconi","year":"2010","journal-title":"World J. Gastroenterol."},{"key":"ref_150","unstructured":"Tjonneland, A., Overvad, K., Bergmann, M.M., Nagel, G., Linseisen, J., Hallmans, G., Palmqvist, R., Sjodin, H., Hagglund, G., and Berglund, G. (2009). Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: A nested case-control study within a European prospective cohort study. Gut."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1194\/jlr.M200361-JLR200","article-title":"Differential modulation of Toll-like receptors by fatty acids: Preferential inhibition by n-3 polyunsaturated fatty acids","volume":"44","author":"Lee","year":"2003","journal-title":"J. Lipid Res."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.clnu.2011.05.002","article-title":"Anti-inflammatory and anti-angiogenic effect of long chain n-3 polyunsaturated fatty acids in intestinal microvascular endothelium","volume":"30","author":"Ibrahim","year":"2011","journal-title":"Clin. Nutr."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"8518","DOI":"10.3390\/nu7105412","article-title":"Effects of dietary plant sterols and stanol esters with low- and high-fat diets in chronic and acute models for experimental colitis","volume":"7","author":"Heinsbroek","year":"2015","journal-title":"Nutrients"},{"key":"ref_154","unstructured":"U.S. Department of Agriculture (2013). Agricultural Research Service USDA National Nutrient Database for Standard Reference, Release 26."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.2174\/156802611796235062","article-title":"Mediterranean Diet and Oxidation: Nuts and Olive Oil as Important Sources of Fat and Antioxidants","volume":"11","year":"2011","journal-title":"Curr. Top. Med. Chem."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1017\/S095442241100014X","article-title":"Tree nut phytochemicals: Composition, antioxidant capacity, bioactivity, impact factors. A systematic review of almonds, Brazils, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts","volume":"24","author":"Bolling","year":"2011","journal-title":"Nutr. Res. Rev."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.1017\/S0007114514003250","article-title":"Nutrition attributes and health effects of pistachio nuts","volume":"113","author":"Bullo","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1080\/07315724.2006.10719538","article-title":"Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review","volume":"25","author":"Dietrich","year":"2006","journal-title":"J. Am. Coll. Nutr."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"372","DOI":"10.7326\/0003-4819-145-5-200609050-00135","article-title":"The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: A systematic review for a National Institutes of Health state-of-the-science conference","volume":"145","author":"Huang","year":"2006","journal-title":"Ann. Intern. Med."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1002\/ijc.25201","article-title":"Incidence of cancers, ischemic cardiovascular diseases and mortality during 5-year follow-up after stopping antioxidant vitamins and minerals supplements: A postintervention follow-up in the SU.VI.MAX Study","volume":"127","author":"Hercberg","year":"2010","journal-title":"Int. J. Cancer"},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1093\/jn\/130.3.503","article-title":"Dietary factors that affect the bioavailability of carotenoids","volume":"130","author":"West","year":"2000","journal-title":"J. Nutr."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1021\/jf062533i","article-title":"Antioxidant activity of Sicilian pistachio (Pistacia vera L. Var. Bronte) nut extract and its bioactive components","volume":"55","author":"Gentile","year":"2007","journal-title":"J. Agric. Food Chem."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.3945\/jn.109.117366","article-title":"Pistachios increase serum antioxidants and lower serum oxidized-LDL in hypercholesterolemic adults","volume":"140","author":"Kay","year":"2010","journal-title":"J. Nutr."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.numecd.2005.08.004","article-title":"Effects of pistachio nuts consumption on plasma lipid profile and oxidative status in healthy volunteers","volume":"16","author":"Kocyigit","year":"2006","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.nut.2009.05.023","article-title":"Effect of pistachio diet on lipid parameters, endothelial function, inflammation, and oxidative status: A prospective study","volume":"26","author":"Sari","year":"2010","journal-title":"Nutrition"},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1093\/jn\/nxy004","article-title":"Walnut Consumption Alters the Gastrointestinal Microbiota, Microbially Derived Secondary Bile Acids, and Health Markers in Healthy Adults: A Randomized Controlled Trial","volume":"148","author":"Holscher","year":"2018","journal-title":"J. Nutr."},{"key":"ref_167","doi-asserted-by":"crossref","unstructured":"Bamberger, C., Rossmeier, A., Lechner, K., Wu, L., Waldmann, E., Fischer, S., Stark, R.G., Altenhofer, J., Henze, K., and Parhofer, K.G. (2018). A Walnut-Enriched Diet Affects Gut Microbiome in Healthy Caucasian Subjects: A Randomized, Controlled Trial. Nutrients, 10.","DOI":"10.3390\/nu10020244"},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1016\/j.jnutbio.2012.06.009","article-title":"Walnut diet reduces accumulation of polyubiquitinated proteins and inflammation in the brain of aged rats","volume":"24","author":"Poulose","year":"2013","journal-title":"J. Nutr. Biochem."},{"key":"ref_169","doi-asserted-by":"crossref","unstructured":"Holscher, H.D., Taylor, A.M., Swanson, K.S., Novotny, J.A., and Baer, D.J. (2018). Almond consumption and processing affects the composition of the gastrointestinal microbiota of healthy adult men and women: A randomized controlled trial. Nutrients, 10.","DOI":"10.3390\/nu10020126"},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/j.nut.2009.05.012","article-title":"The essence of chocolate: A rich, dark, and well-kept secret","volume":"25","author":"McShea","year":"2009","journal-title":"Nutrition"},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0963-9969(00)00068-5","article-title":"Review on polyphenols in Theobroma cacao: Changes in composition during the manufacture of chocolate and methodology for identification and quantification","volume":"33","author":"Wollgast","year":"2000","journal-title":"Food Res. Int."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2017.00677","article-title":"Cocoa and dark chocolate polyphenols: From biology to clinical applications","volume":"8","author":"Magrone","year":"2017","journal-title":"Front. Immunol."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"1002S","DOI":"10.1093\/ajcn\/60.6.1002S","article-title":"Effect of triglyceride structure on fat absorption","volume":"60","author":"Bracco","year":"1994","journal-title":"Am. J. Clin. Nutr."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1001\/archinte.160.15.2374","article-title":"Effect of cocoa bran on low-density lipoprotein oxidation and fecal bulking","volume":"160","author":"Jenkins","year":"2000","journal-title":"Arch. Intern. Med."},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/jn\/138.3.439","article-title":"Metabolic effects of dietary fiber consumption and prevention of diabetes","volume":"138","author":"Weickert","year":"2008","journal-title":"J. Nutr."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1053\/jada.2003.50028","article-title":"Cocoa and chocolate flavonoids: Implications for cardiovascular health","volume":"103","author":"Steinberg","year":"2003","journal-title":"J. Am. Diet. Assoc."},{"key":"ref_177","first-page":"275","article-title":"Magnesium and ischemic heart disease: A review of epidemiological, experimental, and clinical evidences","volume":"18","author":"Ueshima","year":"2005","journal-title":"Magnes. Res."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1139\/y00-054","article-title":"Copper deficiency and cardiovascular disease: Role of peroxidation, glycation, and nitration","volume":"78","author":"Saari","year":"2000","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2174\/157016110790226561","article-title":"Protective effect of dietary potassium against cardiovascular damage in salt-sensitive hypertension: Possible role of its antioxidant action","volume":"8","author":"Ando","year":"2010","journal-title":"Curr. Vasc. Pharmacol."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1017\/S1368980008002401","article-title":"Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993\u20132005","volume":"12","author":"McLean","year":"2009","journal-title":"Public Health Nutr."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.numecd.2011.03.015","article-title":"Cocoa consumption reduces NF-\u03baB activation in peripheral blood mononuclear cells in humans","volume":"23","author":"Sacanella","year":"2013","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1136\/gut.2006.094599","article-title":"Polyphenols in the treatment of inflammatory bowel disease and acute pancreatitis","volume":"56","author":"Shapiro","year":"2007","journal-title":"Gut"},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"4271","DOI":"10.2174\/138161206778743565","article-title":"Immunomodulating effects of flavonoids on acute and chronic inflammatory responses caused by tumor necrosis factor alpha","volume":"12","author":"Kumazawa","year":"2006","journal-title":"Curr. Pharm. Des."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1258\/ebm.2012.012083","article-title":"Effects of a cocoa diet on an intestinal inflammation model in rats","volume":"237","author":"Franch","year":"2012","journal-title":"Exp. Biol. Med."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"6474","DOI":"10.1021\/jf2008925","article-title":"Inhibition of ulcerative colitis in mice after oral administration of a polyphenol-enriched cocoa extract is mediated by the inhibition of STAT1 and STAT3 phosphorylation in colon cells","volume":"59","author":"Recio","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1753-4887.2009.00210.x","article-title":"Dietary polyphenols can modulate the intestinal inflammatory response","volume":"67","author":"Romier","year":"2009","journal-title":"Nutr. Rev."},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"e9070","DOI":"10.1097\/MD.0000000000009070","article-title":"Beverage consumption and risk of ulcerative colitis","volume":"96","author":"Nie","year":"2017","journal-title":"Medicine"},{"key":"ref_188","doi-asserted-by":"crossref","unstructured":"Magee, E.A., Edmond, L.M., Tasker, S.M., Kong, S.C., Curno, R., and Cummings, J.H. (2005). Associations between diet and disease activity in ulcerative colitis patients using a novel method of data analysis. Nutr. J., 4.","DOI":"10.1186\/1475-2891-4-7"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1007\/s00535-013-0865-3","article-title":"Oral caffeine administration ameliorates acute colitis by suppressing chitinase 3-like 1 expression in intestinal epithelial cells","volume":"49","author":"Lee","year":"2014","journal-title":"J. Gastroenterol."},{"key":"ref_190","first-page":"335","article-title":"Effect of Green Tea Extract on Growth of Intestinal Bacteria","volume":"3","author":"Ahn","year":"1990","journal-title":"Microb. Ecol. Health Dis."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ctim.2019.01.015","article-title":"Green tea: A possibility in the therapeutic approach of inflammatory bowel diseases?","volume":"43","author":"Barbalho","year":"2019","journal-title":"Complement. Ther. Med."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/MIB.0000000000000638","article-title":"Dietary Patterns and Risk of Inflammatory Bowel Disease in Europe: Results from the EPIC Study","volume":"22","author":"Racine","year":"2016","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_193","doi-asserted-by":"crossref","unstructured":"Khalili, H., Hakansson, N., Chan, S.S., Ludvigsson, J.F., Olen, O., Chan, A.T., Hart, A.R., and Wolk, A. (2018). No Association Between Consumption of Sweetened Beverages and Risk of Later-Onset Crohn\u2019s Disease or Ulcerative Colitis. Clin. Gastroenterol. Hepatol.","DOI":"10.1016\/j.cgh.2018.04.059"},{"key":"ref_194","doi-asserted-by":"crossref","unstructured":"Manzini, R., Schwarzfischer, M., Bircher, A., Niechcial, A., Vavricka, S.R., Atrott, K., Lang, S., Scharl, M., and Spalinger, M.R. (2021). Energy Drink Administration Ameliorates Intestinal Epithelial Barrier Defects and Reduces Acute DSS Colitis. Inflamm. Bowel Dis.","DOI":"10.1093\/ibd\/izaa328"},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.cca.2010.11.034","article-title":"Modulation of endogenous antioxidant system by wine polyphenols in human disease","volume":"412","author":"Rodrigo","year":"2011","journal-title":"Clin. Chim. Acta"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.redox.2014.06.008","article-title":"Wine consumption and intestinal redox homeostasis","volume":"2","author":"Biasi","year":"2014","journal-title":"Redox Biol."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.atherosclerosis.2009.06.031","article-title":"Wine and oxidative stress: Up-to-date evidence of the effects of moderate wine consumption on oxidative damage in humans","volume":"208","author":"Covas","year":"2010","journal-title":"Atherosclerosis"},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/j.fm.2011.06.005","article-title":"Effect of grape polyphenols on lactic acid bacteria and bifidobacteria growth: Resistance and metabolism","volume":"28","author":"Tabasco","year":"2011","journal-title":"Food Microbiol."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.mrfmmm.2005.04.022","article-title":"Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats","volume":"591","author":"Dolara","year":"2005","journal-title":"Mutat. Res."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1002\/nbm.1233","article-title":"(1)H NMR metabolite profiling of feces as a tool to assess the impact of nutrition on the human microbiome","volume":"21","author":"Jacobs","year":"2008","journal-title":"NMR Biomed."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.aca.2011.11.011","article-title":"Chemistry of ascorbic acid and sulfur dioxide as an antioxidant system relevant to white wine","volume":"732","author":"Barril","year":"2012","journal-title":"Anal. Chim. Acta"},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1093\/alcalc\/agt007","article-title":"Effects of wine, alcohol and polyphenols on cardiovascular disease risk factors: Evidences from human studies","volume":"48","author":"Arranz","year":"2013","journal-title":"Alcohol Alcohol."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000329403","article-title":"Is moderate red wine consumption safe in inactive inflammatory bowel disease?","volume":"84","author":"Swanson","year":"2011","journal-title":"Digestion"},{"key":"ref_204","first-page":"200","article-title":"Alcohol consumption and the gastrointestinal tract","volume":"4","author":"Stermer","year":"2002","journal-title":"Isr. Med. Assoc. J."},{"key":"ref_205","first-page":"191","article-title":"V Role of the brain-gut axis in alcohol-related gastrointestinal diseases\u2014What can we learn from new animal models?","volume":"54","author":"Siegmund","year":"2003","journal-title":"J. Physiol. Pharmacol."},{"key":"ref_206","doi-asserted-by":"crossref","unstructured":"Carbonero, F., Benefiel, A.C., Alizadeh-Ghamsari, A.H., and Gaskins, H.R. (2012). Microbial pathways in colonic sulfur metabolism and links with health and disease. Front. Physiol., 3.","DOI":"10.3389\/fphys.2012.00448"},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1080\/00365520701452241","article-title":"Effects of five different alcoholic drinks on patients with Crohn\u2019s disease","volume":"42","author":"Hey","year":"2007","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1111\/acer.13519","article-title":"Alcohol Feeding in Mice Promotes Colonic Hyperpermeability and Changes in Colonic Organoid Stem Cell Fate","volume":"41","author":"Forsyth","year":"2017","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/j.1365-2036.2007.03442.x","article-title":"Review article: Yeast as probiotics\u2014Saccharomyces boulardii","volume":"26","author":"Czerucka","year":"2007","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/00042737-199803000-00008","article-title":"Nutritional factors in inflammatory bowel disease","volume":"10","author":"Hunter","year":"1998","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1080\/08923973.2018.1469143","article-title":"Review of Saccharomyces boulardii as a treatment option in IBD","volume":"40","author":"Sivananthan","year":"2018","journal-title":"Immunopharmacol. Immunotoxicol."},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1080\/00365520801943354","article-title":"Influence of Saccharomyces boulardii on the intestinal permeability of patients with Crohn\u2019s disease in remission","volume":"43","year":"2008","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1023\/A:1005588911207","article-title":"Saccharomyces boulardii in Maintenance Treatment of Crohn\u2019s Disease","volume":"45","author":"Guslandi","year":"2000","journal-title":"Dig. Dis. Sci."},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/00042737-200306000-00017","article-title":"A pilot trial of Saccharomyces boulardii in ulcerative colitis","volume":"15","author":"Guslandi","year":"2003","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.cgh.2013.02.021","article-title":"Saccharomyces boulardii does not prevent relapse of Crohn\u2019s disease","volume":"11","author":"Bourreille","year":"2013","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_216","doi-asserted-by":"crossref","unstructured":"Zeng, L., Hu, S., Chen, P., Wei, W., and Tan, Y. (2017). Macronutrient Intake and Risk of Crohn\u2019s Disease: Systematic Review and Dose-Response Meta-Analysis of Epidemiological Studies. Nutrients, 9.","DOI":"10.3390\/nu9050500"},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1002\/jor.23230","article-title":"High-fat high-sucrose diet leads to dynamic structural and inflammatory alterations in the rat vastus lateralis muscle","volume":"34","author":"Collins","year":"2016","journal-title":"J. Orthop. Res."},{"key":"ref_218","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbr.2016.03.018","article-title":"Short-term exposure to a diet high in fat and sugar, or liquid sugar, selectively impairs hippocampal-dependent memory, with differential impacts on inflammation","volume":"306","author":"Beilharz","year":"2016","journal-title":"Behav. Brain Res."},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/MOG.0000000000000144","article-title":"Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease","volume":"31","author":"Hosomi","year":"2015","journal-title":"Curr. Opin. Gastroenterol."},{"key":"ref_220","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.2217\/imt.13.130","article-title":"Influence of host immunoregulatory genes, ER stress and gut microbiota on the shared pathogenesis of inflammatory bowel disease and Type 1 diabetes","volume":"5","author":"Gjymishka","year":"2013","journal-title":"Immunotherapy"},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.clnu.2016.10.009","article-title":"Carbohydrate and protein intake and risk of ulcerative colitis: Systematic review and dose-response meta-analysis of epidemiological studies","volume":"36","author":"Wang","year":"2017","journal-title":"Clin. Nutr."},{"key":"ref_222","first-page":"1","article-title":"Patterns of Complementary and Alternative Medicine Use in Saudi Arabian Patients with Inflammatory Bowel Disease: A Cross-Sectional Study","volume":"12","author":"Altunisi","year":"2020","journal-title":"Cureus"},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2020.577237","article-title":"Acacetin Ameliorates Experimental Colitis in Mice via Inhibiting Macrophage Inflammatory Response and Regulating the Composition of Gut Microbiota","volume":"11","author":"Ren","year":"2021","journal-title":"Front. Physiol."},{"key":"ref_224","doi-asserted-by":"crossref","unstructured":"Khalili, H., Malik, S., Ananthakrishnan, A.N., Garber, J.J., Higuchi, L.M., Joshi, A., Peloquin, J., Richter, J.M., Stewart, K.O., and Curhan, G.C. (2016). Identification and characterization of a novel association between dietary potassium and risk of Crohn\u2019s disease and ulcerative colitis. Front. Immunol., 7.","DOI":"10.3389\/fimmu.2016.00554"},{"key":"ref_225","doi-asserted-by":"crossref","unstructured":"Zhou, X., Zhang, L., Ji, W.J., Yuan, F., Guo, Z.Z., Pang, B., Luo, T., Liu, X., Zhang, W.C., and Jiang, T.M. (2013). Variation in Dietary Salt Intake Induces Coordinated Dynamics of Monocyte Subsets and Monocyte-Platelet Aggregates in Humans: Implications in End Organ Inflammation. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0060332"},{"key":"ref_226","doi-asserted-by":"crossref","unstructured":"Wen, W., Wan, Z., Ren, K., Zhou, D., Gao, Q., Wu, Y., Wang, L., Yuan, Z., and Zhou, J. (2016). Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38\/MAPK-SGK1 pathway. Exp. Mol. Pathol.","DOI":"10.1016\/j.yexmp.2016.03.009"},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.trsl.2014.11.007","article-title":"Effects of dietary salt levels on monocytic cells and immune responses in healthy human subjects: A longitudinal study","volume":"166","author":"Yi","year":"2015","journal-title":"Transl. Res."},{"key":"ref_228","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.4049\/jimmunol.1700356","article-title":"Dietary Salt Exacerbates Experimental Colitis","volume":"199","author":"Tubbs","year":"2017","journal-title":"J. Immunol."},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/ecco-jcc\/jjw139","article-title":"Sodium chloride-enriched Diet Enhanced Inflammatory Cytokine Production and Exacerbated Experimental Colitis in Mice","volume":"11","author":"Monteleone","year":"2017","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_230","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/nature11868","article-title":"Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells","volume":"496","author":"Kleinewietfeld","year":"2013","journal-title":"Nature"},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nature11984","article-title":"Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1","volume":"496","author":"Wu","year":"2013","journal-title":"Nature"},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nature11981","article-title":"Dynamic regulatory network controlling TH17 cell differentiation","volume":"496","author":"Yosef","year":"2013","journal-title":"Nature"},{"key":"ref_233","doi-asserted-by":"crossref","unstructured":"Hernandez, A.L., Kitz, A., Wu, C., Lowther, D.E., Rodriguez, D.M., Vudattu, N., Deng, S., Herold, K.C., Kuchroo, V.K., and Kleinewietfeld, M. (2015). Sodium chloride inhibits the suppressive function of FOXP3 + regulatory T cells. J. Clin. Investig., 125.","DOI":"10.1172\/JCI81151"},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"70","DOI":"10.18632\/oncotarget.13783","article-title":"High salt diet stimulates gut Th17 response and exacerbates TNBS-induced colitis in mice","volume":"8","author":"Wei","year":"2016","journal-title":"Oncotarget"},{"key":"ref_235","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1038\/cr.2015.87","article-title":"High salt primes a specific activation state of macrophages, M(Na)","volume":"25","author":"Zhang","year":"2015","journal-title":"Cell Res."},{"key":"ref_236","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1172\/JCI80919","article-title":"High salt reduces the activation of IL-4- and IL-13-stimulated macrophages","volume":"125","author":"Binger","year":"2015","journal-title":"J. Clin. Investig."},{"key":"ref_237","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s40168-018-0433-4","article-title":"High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production","volume":"6","author":"Miranda","year":"2018","journal-title":"Microbiome"},{"key":"ref_238","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1093\/ije\/dyp139","article-title":"Salt intakes around the world: Implications for public health","volume":"38","author":"Brown","year":"2009","journal-title":"Int. J. Epidemiol."},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1053\/j.gastro.2011.01.055","article-title":"Epidemiology and Natural History of Inflammatory Bowel Diseases","volume":"140","author":"Cosnes","year":"2011","journal-title":"Gastroenterology"},{"key":"ref_240","first-page":"210","article-title":"Herbal and plant therapy in patients with inflammatory bowel disease","volume":"28","author":"Triantafyllidi","year":"2015","journal-title":"Ann. Gastroenterol."},{"key":"ref_241","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.gtc.2017.08.009","article-title":"Herbs and Inflammatory Bowel Disease","volume":"46","author":"Rampton","year":"2017","journal-title":"Gastroenterol. Clin. N. Am."},{"key":"ref_242","doi-asserted-by":"crossref","unstructured":"Omer, B., Krebs, S., Omer, H., and Noor, T.O. (2007). Steroid-sparing effect of wormwood (Artemisia absinthium) in Crohn\u2019s disease: A double-blind placebo-controlled study. Phytomedicine.","DOI":"10.1016\/j.phymed.2007.01.001"},{"key":"ref_243","doi-asserted-by":"crossref","unstructured":"Krebs, S., Omer, T.N., and Omer, B. (2010). Wormwood (Artemisia absinthium) suppresses tumour necrosis factor alpha and accelerates healing in patients with Crohn\u2019s disease\u2014A controlled clinical trial. Phytomedicine.","DOI":"10.1016\/j.phymed.2009.10.013"},{"key":"ref_244","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1055\/s-2001-10708","article-title":"Therapie des aktiven Morbus Crohn mit dem Boswellia-serrata-Extrakt H 15","volume":"39","author":"Gerhardt","year":"2001","journal-title":"Z. Gastroenterol."},{"key":"ref_245","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/ibd.21345","article-title":"Randomized, placebo-controlled, double-blind trial of Boswellia serrata in maintaining remission of Crohn\u2019s disease","volume":"17","author":"Holtmeier","year":"2011","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_246","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1177\/0300060512474744","article-title":"Prevention of postoperative recurrence of Crohn\u2019s disease: Tripterygium wilfordii polyglycoside versus mesalazine","volume":"41","author":"Ren","year":"2013","journal-title":"J. Int. Med. Res."},{"key":"ref_247","doi-asserted-by":"crossref","unstructured":"Zhu, W., Li, Y., Gong, J., Zuo, L., Zhang, W., Cao, L., Gu, L., Guo, Z., Li, N., and Li, J. (2015). Tripterygium wilfordii Hook. f. versus azathioprine for prevention of postoperative recurrence in patients with Crohn\u2019s disease: A randomized clinical trial. Dig. Liver Dis.","DOI":"10.1016\/j.dld.2014.09.008"},{"key":"ref_248","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/MAJ.0000000000000591","article-title":"Tripterygium wilfordii Hook F as Maintenance Treatment for Crohn\u2019s Disease","volume":"350","author":"Sun","year":"2015","journal-title":"Am. J. Med. Sci."},{"key":"ref_249","doi-asserted-by":"crossref","unstructured":"Ben-Arye, E., Goldin, E., Wengrower, D., Stamper, A., Kohn, R., and Berry, E. (2002). Wheat grass juice in the treatment of active distal ulcerative colitis: A randomized double-blind placebo-controlled trial. Scand. J. Gastroenterol.","DOI":"10.1080\/003655202317316088"},{"key":"ref_250","doi-asserted-by":"crossref","unstructured":"Tang, T., Targan, S.R., Li, Z.S., Xu, C., Byers, V.S., and Sandborn, W.J. (2011). Randomised clinical trial: Herbal extract HMPL-004 in active ulcerative colitis\u2014A double-blind comparison with sustained release mesalazine. Aliment. Pharmacol. Ther.","DOI":"10.1111\/j.1365-2036.2010.04515.x"},{"key":"ref_251","doi-asserted-by":"crossref","unstructured":"Sandborn, W.J., Targan, S.R., Byers, V.S., Rutty, D.A., Mu, H., Zhang, X., and Tang, T. (2013). Andrographis paniculata extract (HMPL-004) for active ulcerative colitis. Am. J. Gastroenterol.","DOI":"10.1038\/ajg.2012.340"},{"key":"ref_252","first-page":"37","article-title":"Effects of Boswellia serrata gum resin in patients with ulcerative colitis","volume":"2","author":"Gupta","year":"1997","journal-title":"Eur. J. Med. Res."},{"key":"ref_253","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1055\/s-2001-15802","article-title":"Effects of gum resin of Boswellia serrata in patients with chronic colitis","volume":"67","author":"Gupta","year":"2001","journal-title":"Planta Med."},{"key":"ref_254","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.2174\/138161209788489177","article-title":"Curcumin has Bright Prospects for the Treatment of Inflammatory Bowel Disease","volume":"15","author":"Hanai","year":"2009","journal-title":"Curr. Pharm. Des."},{"key":"ref_255","doi-asserted-by":"crossref","unstructured":"Lang, A., Salomon, N., Wu, J.C.Y., Kopylov, U., Lahat, A., Har-Noy, O., Ching, J.Y.L., Cheong, P.K., Avidan, B., and Gamus, D. (2015). Curcumin in Combination with Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial. Clin. Gastroenterol. Hepatol.","DOI":"10.1016\/j.cgh.2015.02.019"},{"key":"ref_256","doi-asserted-by":"crossref","unstructured":"Singla, V., Pratap Mouli, V., Garg, S.K., Rai, T., Choudhury, B.N., Verma, P., Deb, R., Tiwari, V., Rohatgi, S., and Dhingra, R. (2014). Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis\u2014A randomized, placebo-controlled, pilot study. J. Crohn\u2019s Colitis.","DOI":"10.1016\/j.crohns.2013.08.006"},{"key":"ref_257","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1016\/j.cgh.2006.08.008","article-title":"Curcumin Maintenance Therapy for Ulcerative Colitis: Randomized","volume":"4","author":"Hanai","year":"2006","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_258","doi-asserted-by":"crossref","unstructured":"Garg, S.K., Ahuja, V., Sankar, M.J., Kumar, A., and Moss, A.C. (2012). Curcumin for maintenance of remission in ulcerative colitis. Cochrane Database Syst. Rev.","DOI":"10.1002\/14651858.CD008424.pub2"},{"key":"ref_259","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1080\/10408398.2018.1456403","article-title":"Curcuminoids from Curcuma Longa: New adjuvants for the treatment of Crohn\u2019s disease and ulcerative colitis?","volume":"59","author":"Neto","year":"2019","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_260","first-page":"321","article-title":"Lemon grass (Cymbopogon citratus) ameliorates murine spontaneous ileitis by decreasing lymphocyte recruitment to the inflamed intestine","volume":"17","author":"Watanabe","year":"2010","journal-title":"Microcirculation"},{"key":"ref_261","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1046\/j.1365-2036.2001.01053.x","article-title":"Review article: Herbal treatment in gastrointestinal and liver disease-benefits and dangers","volume":"15","author":"Langmead","year":"2001","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_262","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S1542-3565(04)00461-6","article-title":"Complementary and alternative medicine in gastroenterology: The good, the bad, and the ugly","volume":"2","author":"Koretz","year":"2004","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_263","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/apt.15045","article-title":"Review article: Emulsifiers in the food supply and implications for gastrointestinal disease","volume":"49","author":"Halmos","year":"2019","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_264","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1136\/gutjnl-2016-313099","article-title":"Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation","volume":"66","author":"Chassaing","year":"2017","journal-title":"Gut"},{"key":"ref_265","doi-asserted-by":"crossref","unstructured":"Llewellyn, S.R., Britton, G.J., Contijoch, E.J., Vennaro, O.H., Mortha, A., Colombel, J.-F., Grinspan, A., Clemente, J.C., Merad, M., and Faith, J.J. (2017). Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice. Gastroenterology.","DOI":"10.1053\/j.gastro.2017.11.030"},{"key":"ref_266","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature14232","article-title":"Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome","volume":"519","author":"Chassaing","year":"2015","journal-title":"Nature"},{"key":"ref_267","doi-asserted-by":"crossref","first-page":"6296","DOI":"10.3748\/wjg.v22.i27.6296","article-title":"Environmental risk factors for inflammatory bowel diseases: Evidence based literature review","volume":"22","author":"Abegunde","year":"2016","journal-title":"World J. Gastroenterol."},{"key":"ref_268","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000342602","article-title":"Microparticles and their impact on intestinal immunity","volume":"30","author":"Becker","year":"2013","journal-title":"Dig. Dis."},{"key":"ref_269","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/00042737-200503000-00019","article-title":"Lack of efficacy of a reduced microparticle diet in a multi-centred trial of patients with active Crohn\u2019s disease","volume":"17","author":"Lomer","year":"2005","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"ref_270","doi-asserted-by":"crossref","first-page":"39511","DOI":"10.1074\/jbc.M110.159681","article-title":"Tumor Necrosis Factor \u03b1-induced Inflammation Is Increased but Apoptosis Is Inhibited by Common Food Additive Carrageenan","volume":"285","author":"Bhattacharyya","year":"2010","journal-title":"J. Biol. Chem."},{"key":"ref_271","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3389\/fped.2017.00096","article-title":"The Role of Carrageenan and Carboxymethylcellulose in the Development of Intestinal Inflammation","volume":"5","author":"Martino","year":"2017","journal-title":"Front. Pediatr."},{"key":"ref_272","doi-asserted-by":"crossref","unstructured":"Nickerson, K.P., Homer, C.R., Kessler, S.P., Dixon, L.J., Kabi, A., Gordon, I.O., Johnson, E.E., de la Motte, C.A., and McDonald, C. (2014). The dietary polysaccharide maltodextrin promotes Salmonella survival and mucosal colonization in mice. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0101789"},{"key":"ref_273","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/0016-5085(90)91297-J","article-title":"An epidemiologic study of inflammatory bowel disease in Rochester, New York. Hospital incidence","volume":"98","author":"Stowe","year":"1990","journal-title":"Gastroenterology"},{"key":"ref_274","doi-asserted-by":"crossref","first-page":"G1115","DOI":"10.1152\/ajpgi.00261.2009","article-title":"Carbohydrate maldigestion induces necrotizing enterocolitis in preterm pigs","volume":"297","author":"Thymann","year":"2009","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"ref_275","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1462-5822.2009.01381.x","article-title":"Crohn\u2019s disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly","volume":"12","author":"Lapaquette","year":"2010","journal-title":"Cell. Microbiol."},{"key":"ref_276","first-page":"61","article-title":"Mucosal flora in Crohn\u2019s disease and ulcerative colitis\u2014An overview","volume":"60","author":"Swidsinski","year":"2009","journal-title":"J. Physiol. Pharmacol."},{"key":"ref_277","doi-asserted-by":"crossref","unstructured":"Nickerson, K.P., and McDonald, C. (2012). Crohn\u2019s Disease-Associated Adherent-Invasive Escherichia coli Adhesion Is Enhanced by Exposure to the Ubiquitous Dietary Polysaccharide Maltodextrin. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0052132"},{"key":"ref_278","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1079\/BJN2001416","article-title":"Increasing viscosity of the intestinal contents alters small intestinal structure and intestinal growth, and stimulates proliferation of enterotoxigenic Escherichia coli in newly-weaned pigs","volume":"86","author":"McDonald","year":"2001","journal-title":"Br. J. Nutr."},{"key":"ref_279","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.jcmgh.2018.09.002","article-title":"The Food Additive Maltodextrin Promotes Endoplasmic Reticulum Stress\u2013Driven Mucus Depletion and Exacerbates Intestinal Inflammation","volume":"7","author":"Laudisi","year":"2019","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"ref_280","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1136\/gutjnl-2019-319505","article-title":"Adherence to a Mediterranean diet is associated with a lower risk of later-onset Crohn\u2019s disease: Results from two large prospective cohort studies","volume":"69","author":"Khalili","year":"2020","journal-title":"Gut"},{"key":"ref_281","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1038\/ajg.2012.260","article-title":"Prevalence of Symptoms Meeting Criteria for Irritable Bowel Syndrome in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis","volume":"107","author":"Halpin","year":"2012","journal-title":"Am. J. Gastroenterol."},{"key":"ref_282","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1097\/MIB.0000000000000708","article-title":"Fermentable carbohydrate restriction (Low FODMAP Diet) in clinical practice improves functional gastrointestinal symptoms in patients with inflammatory bowel disease","volume":"22","author":"Prince","year":"2016","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_283","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.3748\/wjg.v23.i18.3356","article-title":"Low-FODMAP diet reduces irritable bowel symptoms in patients with inflammatory bowel disease","volume":"23","author":"Pedersen","year":"2017","journal-title":"World J. Gastroenterol."},{"key":"ref_284","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/jgh.13690","article-title":"Who should deliver the low FODMAP diet and what educational methods are optimal: A review","volume":"32","author":"Lomer","year":"2017","journal-title":"J. Gastroenterol. Hepatol."},{"key":"ref_285","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/ibd.20968","article-title":"Role of diet in the development of inflammatory bowel disease","volume":"16","author":"Davies","year":"2010","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_286","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/MIB.0000000000001009","article-title":"The Importance and Challenges of Dietary Intervention Trials for Inflammatory Bowel Disease","volume":"23","author":"Lewis","year":"2017","journal-title":"Inflamm. Bowel Dis."}],"container-title":["Nutrients"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6643\/13\/4\/1067\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:41:01Z","timestamp":1760161261000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6643\/13\/4\/1067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,25]]},"references-count":286,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,4]]}},"alternative-id":["nu13041067"],"URL":"https:\/\/doi.org\/10.3390\/nu13041067","relation":{},"ISSN":["2072-6643"],"issn-type":[{"value":"2072-6643","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,25]]}}}