{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T04:26:25Z","timestamp":1772771185549,"version":"3.50.1"},"reference-count":30,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T00:00:00Z","timestamp":1616716800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>A major problem of oral iron supplementation efficacy in children is its tolerability and compliance. We aimed to determine the safety and efficacy of a novel food supplement &gt;Your&lt; Iron Syrup in the replenishment of iron stores and improvement of hematological parameters in iron-deficient children aged nine months to six years. We randomized 94 healthy children with iron deficiency in a ratio of 3:1 to either receive &gt;Your&lt; Iron Syrup or placebo. A 12-week supplementation with &gt;Your&lt; Iron Syrup resulted in a significant increase in ferritin and hemoglobin levels as compared to placebo (p = 0.04 and p = 0.02). Adverse events were reported with similar frequencies across both study arms. &gt;Your&lt; Iron Syrup represents an effective, well-tolerated, and safe option for the management of nutritional iron deficiency in children.<\/jats:p>","DOI":"10.3390\/nu13041087","type":"journal-article","created":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T13:17:53Z","timestamp":1616764673000},"page":"1087","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Micronized, Microencapsulated Ferric Iron Supplementation in the Form of &gt;Your&lt; Iron Syrup Improves Hemoglobin and Ferritin Levels in Iron-Deficient Children: Double-Blind, Randomized Clinical Study of Efficacy and Safety"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6245-7853","authenticated-orcid":false,"given":"Aida","family":"Ze\u010dkanovi\u0107","sequence":"first","affiliation":[{"name":"Department of Pediatric Hematology and Oncology, University Children\u2019s Hospital, University Medical Centre Ljubljana, Bohori\u010deva ulica 20, 1000 Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marko","family":"Kav\u010di\u010d","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology, University Children\u2019s Hospital, University Medical Centre Ljubljana, Bohori\u010deva ulica 20, 1000 Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toma\u017e","family":"Prelog","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology, University Children\u2019s Hospital, University Medical Centre Ljubljana, Bohori\u010deva ulica 20, 1000 Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alenka","family":"\u0160mid","sequence":"additional","affiliation":[{"name":"The Chair of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, A\u0161ker\u010deva cesta 7, 1000 Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7426-1591","authenticated-orcid":false,"given":"Janez","family":"Jazbec","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology, University Children\u2019s Hospital, University Medical Centre Ljubljana, Bohori\u010deva ulica 20, 1000 Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e77","DOI":"10.1016\/S2214-109X(13)70046-9","article-title":"Effect of daily iron supplementation on health in children aged 4-23 months: A systematic review and meta-analysis of randomised controlled trials","volume":"1","author":"Pasricha","year":"2013","journal-title":"Lancet Glob. 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