{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T18:55:27Z","timestamp":1791053727057,"version":"4.1.0"},"reference-count":80,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T00:00:00Z","timestamp":1616976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Background: Zinc is an essential trace element for the normal growth and development of human beings. The main objective was to evaluate the nutritional status of zinc and its association with nutritional indicators in a series of children with chronic diseases. Methods: The prevalence of patients with dietary zinc deficiency or deficit zinc intake (&lt;80% DRI: dietary reference intake) was analyzed through prospective 72 h dietary surveys, and serum zinc deficiency or hypozincemia (\u226470 \u00b5g\/dL in children under 10 years of age in both sexes and in females older than 10 years and &lt;74 \u03bcg\/dL in males older than 10 years) was measured through atomic absorption spectrophotometry. The participants were classified according to their nutritional status by body mass index (BMI). Results: Mean serum zinc level in obese (87 \u00b5g\/dL), undernourished (85 \u00b5g\/dL), and eutrophic children (88 \u00b5g\/dL) were normal, but in the undernutrition (60% DRI) and eutrophic (67% DRI) groups the mean dietary zinc intake was low compared to that in the obesity group (81% DRI). There were different associations between nutritional parameters, dietary zinc intake, and serum zinc. All patients with hypozincemia had dietary zinc deficiency. Conclusions: In the whole series, 69% of participants showed a zinc intake lower than recommended and might be at high risk of zinc deficiency.<\/jats:p>","DOI":"10.3390\/nu13041121","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T16:01:57Z","timestamp":1617033717000},"page":"1121","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Zinc Nutritional Status in a Series of Children with Chronic Diseases: A Cross-Sectional Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1295-3752","authenticated-orcid":false,"given":"Marlene Fabiola","family":"Escobedo-Monge","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Valladolid University, Avenida Ram\u00f3n y Cajal, 7, 47005 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Carmen","family":"Torres-Hinojal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Valladolid University, Avenida Ram\u00f3n y Cajal, 7, 47005 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Barrado","sequence":"additional","affiliation":[{"name":"Department of Analytical Chemistry, Science Faculty, University of Valladolid, Campus Miguel Delibes, Calle Paseo de Bel\u00e9n, 7, 47011 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6318-7333","authenticated-orcid":false,"given":"Mar\u00eda Antonieta","family":"Escobedo-Monge","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Science Faculty, University of Burgos, Plaza Misael Ba\u00f1uelos sn, 09001 Burgos, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7255-7578","authenticated-orcid":false,"given":"Jos\u00e9 Manuel","family":"Marug\u00e1n-Miguelsanz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics of the Faculty of Medicine, Valladolid University, Section of Gastroenterology and Pediatric Nutrition, University Clinical Hospital of Valladolid, Avenida Ram\u00f3n y Cajal, 7, 47005 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1007\/s00431-008-0697-y","article-title":"Defining chronic diseases and health conditions in childhood (0\u201318 years of age): National consensus in the Netherlands","volume":"167","author":"Mokkink","year":"2008","journal-title":"Eur. 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