{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:34:15Z","timestamp":1790814855422,"version":"4.1.0"},"reference-count":77,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T00:00:00Z","timestamp":1621209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>The iron absorption process developsmainly in the proximal duodenum. This portion of the intestine is typically destroyed in celiac disease (CD), resulting in a reduction in absorption of iron and subsequent iron deficiency anemia (IDA). In fact, the most frequent extra-intestinal manifestation (EIM) of CD is IDA, with a prevalence between 12 and 82% (in relation with the various reports) in patients with new CD diagnosis. The primary treatment of CD is the gluten-free diet (GFD), which is associated with adequate management of IDA, if present. Iron replacement treatment historically has been based on oral products containing ferrous sulphate (FS). However, the absorption of FS is limited in patients with active CD and unpredictable in patients on a GFD. Furthermore, a poor tolerability of this kind of ferrous is particularly frequent in patients with CD or with other inflammatory bowel diseases. Normalization from anemic state typically occurs after at least 6 months of GFD, but the process can take up to 2 years for iron stores to replenish.<\/jats:p>","DOI":"10.3390\/nu13051695","type":"journal-article","created":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T05:45:13Z","timestamp":1621230313000},"page":"1695","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Iron Deficiency Anemia in Celiac Disease"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9027-6921","authenticated-orcid":false,"given":"Valentina","family":"Talarico","sequence":"first","affiliation":[{"name":"Department of Pediatric, Pugliese-Ciaccio Hospital, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Giancotti","sequence":"additional","affiliation":[{"name":"Unit of Pediatrics, University \u201cMagna Graecia\u201d, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Antonio","family":"Mazza","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Regina Margherita Hospital, Citt\u00e0 della Salute e della Scienza, 10126 Torino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Miniero","sequence":"additional","affiliation":[{"name":"Department of Pediatric, Pugliese-Ciaccio Hospital, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1469-7825","authenticated-orcid":false,"given":"Marco","family":"Bertini","sequence":"additional","affiliation":[{"name":"R&amp;D Department, Laboratori Baldacci SpA, 56121 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ejim.2017.04.018","article-title":"Clinical management of iron deficiency anemia in adults: Sistemic review on advances in diagnosis and treatment","volume":"42","author":"Iolascon","year":"2017","journal-title":"Eur. J. Intern. Med."},{"key":"ref_2","unstructured":"Kliegman, R.M., Stanton, B.F., Schor, N.F., St. Gemelli, G.V., and Behrman, R.E. (2016). Iron deficiency anemia. Nelson Text of Pediatrics, Elseviere. [20th ed.]."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1182\/blood-2018-05-815944","article-title":"Iron deficiency","volume":"133","author":"Camaschella","year":"2019","journal-title":"Blood"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1007\/s00277-019-03707-w","article-title":"Gender differences in determinants of iron-deficiency anemia: A population-based study conducted in four European countries","volume":"98","author":"Levi","year":"2019","journal-title":"Ann. Hematol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1590\/s0004-2803.201800000-15","article-title":"Association of potential celiac disease and refractory iron deficiency anemia in children and adolescents","volume":"55","author":"Shahriari","year":"2018","journal-title":"Arq. Gastroenterol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s13312-018-1221-8","article-title":"Celiac Disease and Anemia","volume":"24","author":"Mittal","year":"2018","journal-title":"Indian Pediatr."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Kreutz, J.M., Adriaanse, M.P.M., vander Ploeg, E.M.C., and Vreugdenhil, A.C.E. (2020). Narrative Review: Nutrient Deficiencies in Adults and Children with Treated and Untreated Celiac Disease. Nutrients, 12.","DOI":"10.3390\/nu12020500"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"9233","DOI":"10.3748\/wjg.v21.i31.9233","article-title":"Iron deficiency anemia in celiac disease","volume":"21","author":"Freeman","year":"2015","journal-title":"World J. Gastroenterol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/MCG.0000000000001267","article-title":"Celiac Disease Extraintestinal Manifestations and Associated Conditions","volume":"54","author":"Therrien","year":"2020","journal-title":"J. Clin. Gastroenterol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1080\/20009666.2017.1396169","article-title":"Prevalence of occult celiac disease in females with iron deficiency in the United States: An NHANES analysis","volume":"7","author":"Abdallaa","year":"2017","journal-title":"J. Community Hosp. Intern. Med. Perspect."},{"key":"ref_11","first-page":"75","article-title":"Extraintestinal Manifestations of Celiac Disease","volume":"65","author":"Jericho","year":"2017","journal-title":"JPGN"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3389\/fped.2019.00056","article-title":"Extra-Intestinal Manifestations of Coeliac Disease in Children: Clinical Features and Mechanisms","volume":"7","author":"Nardecchia","year":"2019","journal-title":"Front. Pediatr."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1080\/00365529850172368","article-title":"Undiagnosed celiac disease is commonin Finnish adults","volume":"33","author":"Kolho","year":"1998","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.3324\/haematol.13255","article-title":"Anemia of chronic disease and defective erythropoiet in production in patients with celiac disease","volume":"93","author":"Bergamaschi","year":"2008","journal-title":"Haematologica"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/jgh3.12073","article-title":"Anemia in celiac disease is multifactorial in etiology: A prospective study from India: Anemia in celiac disease","volume":"2","author":"Berry","year":"2018","journal-title":"JGH Open"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1590\/1806-9282.66.1.55","article-title":"Evaluation of adult celiac disease from a tertiary reference center: A retrospective analysis","volume":"66","author":"Binicier","year":"2020","journal-title":"Rev. Assoc. Med. Bras."},{"key":"ref_17","first-page":"691","article-title":"The clinical pattern of subclinical\/silent celiac disease: Analyses is on 1026 consecutive cases","volume":"94","author":"Bottaro","year":"1999","journal-title":"Am. J. Gastroenterol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/j.cgh.2013.05.030","article-title":"Celiac disease patients presenting with anemia have more severe disea than those presenting with diarrhea","volume":"11","author":"AbuDaya","year":"2013","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/MPG.0000000000001634","article-title":"Celiac Disease Symptom Resolution: Effectiveness of the Gluten-free Diet","volume":"66","author":"Sansotta","year":"2018","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/ajh.24991","article-title":"The role of TMPRSS6 and HFE variants in iron deficiency anemia in celiac disease","volume":"93","author":"Tortora","year":"2018","journal-title":"Am. J. Hematol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/10245332.2016.1240933","article-title":"Estimation of iron deficiency anemia in Iranian children and adolescents: A systematic review and meta-analysis","volume":"22","author":"Akbari","year":"2017","journal-title":"Hematology"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s12664-012-0198-9","article-title":"Clinical presentation of celiac disease among pediatric compared to adolescent and adult patients","volume":"31","author":"Kochhar","year":"2012","journal-title":"Indian J. Gastroenterol."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Tolone, C., Bellini, G., Punzo, F., Papparella, A., Miele, E., Vitale, A., Nobili, B., Strisciuglio, C., and Rossi, F. (2017). The DMT1 IVS4+44C>A polymorphis mand the risk of iron deficiency anemia in children with celiac disease. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0185822"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1023\/A:1018896015530","article-title":"Sideropenic anemia and celiac disease: One study, two points of view","volume":"43","author":"Carroccio","year":"1998","journal-title":"Dig. Dis. Sci."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"617","DOI":"10.3349\/ymj.2009.50.5.617","article-title":"Celiac disease: Presentation of 109 children","volume":"50","author":"Kuloglu","year":"2009","journal-title":"Yonsei Med. J."},{"key":"ref_26","first-page":"1","article-title":"Iron deficiency anemia in newly diagnosed celiac disease in children","volume":"68","author":"Sanseviero","year":"2016","journal-title":"Minerva Pediatr."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1053\/j.gastro.2018.04.016","article-title":"Prevalence of Celiac Disease in Patients with Iron Deficiency Anemia\u2013a Systematic Review with Meta-analysis","volume":"155","author":"Mahadev","year":"2018","journal-title":"Gastroenterology"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"334","DOI":"10.4318\/tjg.2013.0529","article-title":"The prevalence of celiac disease in children with iron-deficiency anemia","volume":"24","author":"Ertekin","year":"2013","journal-title":"Turk. J. Gastroenterol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/MPH.0000000000000495","article-title":"Prevalence of Celiac Disease in Children with Iron Deficiency Anemia in Van Lake Region of Turkey","volume":"38","author":"Karaman","year":"2016","journal-title":"Pediatr. Hematol. Oncol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/j.1651-2227.2005.tb01964.x","article-title":"The prevalence of celiac diseaseas detected by screening in children with iron deficiency anaemia","volume":"94","author":"Kalayci","year":"2005","journal-title":"Acta Paediatr."},{"key":"ref_31","first-page":"226","article-title":"Screening for celiac disease among Egyptian children","volume":"6","author":"Kamel","year":"2010","journal-title":"Arch. Med. Sci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"756","DOI":"10.4103\/0377-4929.91488","article-title":"Serodiagnosis of celiac disease in children referred for evaluation of anemia: A pediatric hematology unit's experience","volume":"54","author":"Bansal","year":"2011","journal-title":"Indian J. Pathol. Microbiol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1053\/j.gastro.2005.02.014","article-title":"The prevalence of celiac disease in average-risk and at-risk Western European populations: A systematic review","volume":"128","author":"Rostom","year":"2005","journal-title":"Gastroenterology"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.3324\/haematol.2008.000828","article-title":"Iron in gout the mechanism of anemia in celiac disease","volume":"93","author":"Hershko","year":"2008","journal-title":"Haematologica"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3109\/00365529509093254","article-title":"Subclinical coeliac disease is a frequent cause of iron-deficiency anaemia","volume":"30","author":"Corazza","year":"1995","journal-title":"Scand. J. Gastroenterol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1572-0241.2001.03463.x","article-title":"Efficacy of gluten-free diet alone on recovery from iron deficiency anemia in adult celiac patients","volume":"96","author":"Annibale","year":"2001","journal-title":"Am. J. Gastroenterol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1136\/jcp.55.10.754","article-title":"A prospective study of the prevalence of undiagnosed celiac disease in laboratory defined iron and folate deficiency","volume":"55","author":"Howard","year":"2002","journal-title":"J. Clin. Pathol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1136\/pgmj.2003.014670","article-title":"Value of routine duodenal biopsy in diagnosing celiac disease in patients with iron deficiency anaemia","volume":"80","author":"Mandal","year":"2004","journal-title":"Postgrad. Med. J."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1097\/MEG.0000000000000687","article-title":"The incidence of gastrointestinal pathology and subsequent anemia in young men presenting with iron deficiency without anemia","volume":"28","author":"Carter","year":"2016","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.rgmx.2016.12.008","article-title":"Iron-Deficiency anemia as asubclinical celiac disease presentation in an Argentinian population","volume":"82","author":"Lasa","year":"2017","journal-title":"Rev. Gastroenterol. M\u00e9xico"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.amjmed.2017.05.027","article-title":"Delay in Diagnosis of Celiac Disease in Patients Without Gastrointestinal Complaints","volume":"130","author":"Paez","year":"2017","journal-title":"Am. J. Med."},{"key":"ref_42","first-page":"141","article-title":"European Society Paediatric Gastroenterology, Hepatology and Nutrition. Guidelines for Diagnosing Coeliac Disease","volume":"70","author":"Husby","year":"2020","journal-title":"JPGN"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1053\/j.gastro.2020.06.046","article-title":"AGA Clinical Practice Guidelines on th e Gastrointestinal Evaluation of Iron Deficiency Anemia","volume":"159","author":"Ko","year":"2020","journal-title":"Gastroenterology"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1136\/gut.2010.228874","article-title":"British Society of Gastroenterology. Guidelines for the management of iron \u2013deficiency anaemia","volume":"60","author":"Goddard","year":"2011","journal-title":"Gut"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.dld.2019.01.022","article-title":"Diagnosis of chronic anaemia in gastrointestinal disorders: A guideline by the Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) and the Italian Society of Paediatric Gastroenterology Hepatology and Nutrition (SIGENP)","volume":"51","author":"Elli","year":"2019","journal-title":"Dig. Liver Dis."},{"key":"ref_46","first-page":"100","article-title":"How Often Do Hematologists Consider Celiac Disease in Iron-Deficiency Anemia? Results of a National Survey","volume":"12","author":"Smukalla","year":"2014","journal-title":"Clin. Adv. Hematol. Oncol."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Nestares, T., Mart\u00edn-Masot, R., Labella, A., Aparicio, V.A., Flor-Alemany, M., L\u00f3pez-Fr\u00edas, M., and Maldonado, J. (2020). Isa Gluten-Free Diet Enough to Maintain Correct Micronutrients Status in Young Patients with Celiac Disease?. Nutrients, 12.","DOI":"10.3390\/nu12030844"},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Di Nardo, G., Villa, M.P., Conti, L., Ranucci, G., Pacchiarotti, C., Principessa, L., Rauci, U., and Parisei, P. (2019). Nutritional deficiencies in children with celiac disease resulting from a gluten-free diet: A systematic review. Nutrients, 11.","DOI":"10.3390\/nu11071588"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1097\/MCG.0000000000000556","article-title":"Clinical Characteristics and the Dietary Response in Celiac Disease Patients Presenting with or Without Anemia","volume":"51","author":"Saukkonen","year":"2017","journal-title":"Clin. Gastroenterol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/apa.14324","article-title":"Extraintestinal manifestations were common in children with celiac disease and were more prevalent in patients with more severe clinical and histological presentation","volume":"108","author":"Nurminen","year":"2019","journal-title":"Acta Paediatr."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1002\/ajh.20996","article-title":"Anemia in celiac disease is multifactorial in etiology","volume":"82","author":"Harper","year":"2007","journal-title":"Am. J. Hematol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.gie.2019.12.042","article-title":"Diagnostic findings and long-term prognosis in children with anemia undergoing GI endoscopies","volume":"91","author":"Repo","year":"2020","journal-title":"Gastrointest. Endosc."},{"key":"ref_53","first-page":"31672","article-title":"Determinants and Trends of Adherence to a Gluten-Free Diet in Adult Celiac Patients on a Long-Term Follow-Up (2000\u20132020)","volume":"S1542-3565","author":"Schiepatti","year":"2020","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Stefanelli, G., Viscido, A., Longo, S., Magistroni, M., and Latella, G. (2020). Persistent Iron Deficiency Anemia in Patients with Celiac Disease Despite a Gluten-Free Diet. Nutrients, 12.","DOI":"10.3390\/nu12082176"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"Repo, M., Hannula, M., Taavela, J., Hyttinen, J., Isola, J., Hiltunen, P., Popp, A., Kaukinen, K., Kurppa, K., and Lindfors, K. (2021). Iron Transporter Protein Expressions in Children with Celiac Disease. Nutrients, 13.","DOI":"10.3390\/nu13030776"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1152\/physiolgenomics.00211.2003","article-title":"Adaptive changes of duodenal iron transport proteins in celiac disease","volume":"17","author":"Barisani","year":"2004","journal-title":"Physiol. Genom."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/1751-2980.12078","article-title":"Celiac disease: A disease with varied manifestations in adults and adolescents","volume":"14","author":"Sharma","year":"2013","journal-title":"J. Dig. Dis."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Mart\u00edn-Masot, R., Nestares, M.T., Diaz-Castro, J., L\u00f3pez-Aliaga, I., Mu\u00f1ozAlf\u00e9rez, M.J., Moreno-Fernandez, J., and Maldonado, J. (2019). Multifactorial Etiology of Anemia in Celiac Disease and Effect of Gluten-Free Diet: A Comprehensive Review. Nutrients, 11.","DOI":"10.3390\/nu11112557"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/ajg.2014.354","article-title":"Does TMPRSS6RS855791 polymorphism contribute to iron deficiency in treated celiac disease?","volume":"110","author":"Elli","year":"2015","journal-title":"Am. J. Gastroenterol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1017\/S000711451500241X","article-title":"Probiotic strain Lactobacillus plantarum 299v increases iron absorption from an iron supplemented fruit drink: A double-isotope cross-over single-blind study in women of reproductive age","volume":"114","author":"Hoppe","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jpeds.2018.12.026","article-title":"Use of a Probiotic to Enhance Iron Absorption in a Randomized Trial of Pediatric Patients Presenting with Iron Deficiency","volume":"207","author":"Rosen","year":"2019","journal-title":"J. Pediatr."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Ferus, K., Drabinska, N., Krupa-Kozak, U., and Jarocka-Cyrta, E. (2018). Randomized, Placebo-Controlled, Pilot Clinical Trial to Evaluate the Effect of Supplementation with Prebiotic Synergy 1 on Iron Homeostasis in Children and Adolescents with Celiac Disease Treated with a Gluten-Free Diet. Nutrients, 10.","DOI":"10.3390\/nu10111818"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.biopha.2012.06.003","article-title":"Treatment of mil non chemotherapy induced iron deficiency anemia in cancer patients: Comparison between oral ferrous bisglycinate chelate and ferrous sulfate","volume":"66","author":"Ferrari","year":"2012","journal-title":"Biomed. Pharm."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2174\/1573396314666180124101059","article-title":"Efficacy of Supplementation with Iron Sulfate Compared to Iron Bisglycinate Chelate in Preterm Infants","volume":"14","author":"Bagna","year":"2018","journal-title":"Curr. Pediatr. Rev."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"261","DOI":"10.2174\/1573396314666181002170040","article-title":"Iron Bisglycinate Chelate and Polymaltose Iron for the Treatment of Iron Deficiency Anemia: A Pilot Randomized Trial","volume":"14","year":"2018","journal-title":"Curr. Pediatric. Rev."},{"key":"ref_66","first-page":"495","article-title":"Forgotten screening test for iron deficiency anemia: Oral iron absorbtion test","volume":"164","author":"Hacibekiroglu","year":"2013","journal-title":"Clin. Ter."},{"key":"ref_67","first-page":"139","article-title":"Oral iron absorption test with ferrous bisglycinate chelate in children with celiac disease: Preliminary results","volume":"10","author":"Mazza","year":"2019","journal-title":"Minerva Pediatr."},{"key":"ref_68","first-page":"1","article-title":"Oral Iron Absorption Test (OIAT): A forgotten screening test for iron absorption from the gastrointestinal tract. A casa series of Iron Deficiency Anemia (IDA) patients treated with FERALGINE\u00ae","volume":"2","author":"Rondinelli","year":"2017","journal-title":"J. Blood Disord. Med."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"200","DOI":"10.23736\/S1121-421X.19.02572-8","article-title":"Oral iron supplementation with Feralgine\u00ae in inflammatory bowel disease: A retrospective observational study","volume":"65","author":"Vernero","year":"2019","journal-title":"Minerva Gastroenterol. Dietol."},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Giancotti, L., Talarico, V., Mazza, G.A., Marrazzo, S., Gangemi, G., Miniero, R., and Bertini, M. (2019). FERALGINE\u2122 a new approach for Iron Deficiency Anemia in Celiac Patients. Nutrients, 11.","DOI":"10.3390\/nu11040887"},{"key":"ref_71","first-page":"89","article-title":"Iron Deficiency Anemia Refractory to Conventional Therapy but Responsive to Feralgine\u00ae in a Young Woman with Celiac Disease","volume":"14","author":"Talarico","year":"2021","journal-title":"Int. Med. Case Rep. J."},{"key":"ref_72","doi-asserted-by":"crossref","unstructured":"Yu, X., Chen, L., Ding, H., Zhao, Y., and Feng, J. (2019). Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells. Nutrients, 11.","DOI":"10.3390\/nu11030485"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"153","DOI":"10.22358\/jafs\/65704\/2014","article-title":"Ferrous bisglycinate increased iron transportation through DMT1 and PepT1 in pig intestinal epithelial cells compared with ferrous sulphate","volume":"23","author":"Liao","year":"2014","journal-title":"J. Anim. Feed Sci."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1182\/asheducation-2010.1.338","article-title":"Clinical use of intravenous iron: Administration, efficacy, and safety","volume":"2010","author":"Auerbach","year":"2010","journal-title":"Hematol. Am. Soc. Hematol. Educ. Program."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.3748\/wjg.v16.i22.2720","article-title":"Treatment of iron deficiency anemia associated with gastrointestinal tract disease","volume":"16","author":"Bayraktar","year":"2010","journal-title":"Word J. Gastroenterol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/apt.14922","article-title":"Review article: Treating\u2013to \u2013target for inflammatory bowel disease-associated anaemia","volume":"48","author":"Lopez","year":"2018","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"28","DOI":"10.21037\/tp.2019.01.01","article-title":"Ferriccarboxymaltose in the treatment of iron deficiency in pediatric inflammatory bowel disease","volume":"8","author":"Carman","year":"2019","journal-title":"Transl. 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