{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T17:59:25Z","timestamp":1778695165757,"version":"3.51.4"},"reference-count":38,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T00:00:00Z","timestamp":1623888000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrients"],"abstract":"<jats:p>Scientific evidence supports the role of L-glutamine in improving immune function. This could suggest a possible role of L-glutamine in recovery after intense exercise. To this end, the present report aimed to study if oral L-glutamine supplementation could attenuate muscle damage in a group of players of a mainly eccentric sport discipline such as basketball. Participants (n = 12) were supplemented with 6 g\/day of glutamine (G group) or placebo (P group) for 40 days in a crossover study design (20 days with glutamine + 20 days with placebo and vice versa). Blood samples were obtained at the beginning and at the end of each period and markers from exercise-induced muscle damage were determined. The glutamine supplemented group displayed significantly low values of aspartate transaminase, creatine kinase and myoglobin in blood, suggesting less muscle damage compared to the placebo. In addition, adrenocorticotropic hormone levels were lower in the glutamine supplemented group than in the placebo. As a result, the circulating cortisol levels did not increase at the end of the study in the glutamine supplemented group. Altogether, the results indicate that glutamine could help attenuate exercise-induced muscle damage in sport disciplines with predominantly eccentric actions.<\/jats:p>","DOI":"10.3390\/nu13062073","type":"journal-article","created":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T11:20:26Z","timestamp":1623928826000},"page":"2073","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Effect of Glutamine Supplementation on Muscular Damage Biomarkers in Professional Basketball Players"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0236-2817","authenticated-orcid":false,"given":"Alfredo","family":"C\u00f3rdova-Mart\u00ednez","sequence":"first","affiliation":[{"name":"Departamento Bioqu\u00edmica, Biolog\u00eda Molecular y Fisiolog\u00eda, Facultad de Ciencias de la Salud, GIR: \u201cEjercicio F\u00edsico y Envejecimiento\u201d Universidad Valladolid, Campus Universitario \u201cLos Pajaritos\u201d, 42004 Soria, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9131-0615","authenticated-orcid":false,"given":"Alberto","family":"Caballero-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Departamento de Anatom\u00eda y Radiolog\u00eda, Facultad de Ciencias de la Salud, GIR: \u201cEjercicio F\u00edsico y Envejecimiento\u201d Universidad Valladolid, Campus Universitario \u201cLos Pajaritos\u201d, 42004 Soria, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo J","family":"Bello","sequence":"additional","affiliation":[{"name":"Departamento Matem\u00e1ticas, Escuela de Ingenier\u00eda de la Industria Forestal, Agron\u00f3mica y de la Bioenerg\u00eda, GIR: \u201cEjercicio F\u00edsico y Envejecimiento\u201d Universidad Valladolid, Campus Universitario \u201cLos Pajaritos\u201d, 42004 Soria, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6916-608X","authenticated-orcid":false,"given":"Daniel","family":"P\u00e9rez-Valdecantos","sequence":"additional","affiliation":[{"name":"Departamento Bioqu\u00edmica, Biolog\u00eda Molecular y Fisiolog\u00eda, Facultad de Ciencias de la Salud, GIR: \u201cEjercicio F\u00edsico y Envejecimiento\u201d Universidad Valladolid, Campus Universitario \u201cLos Pajaritos\u201d, 42004 Soria, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5128-1672","authenticated-orcid":false,"given":"Enrique","family":"Roche","sequence":"additional","affiliation":[{"name":"Instituto de Bioingenier\u00eda y Departamento de Biolog\u00eda Aplicada-Nutrici\u00f3n, Universidad Miguel Hern\u00e1ndez, 03202 Elche, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), 03010 Alicante, Spain"},{"name":"CIBER Fisiopatolog\u00eda de la Obesidad y Nutrici\u00f3n (CIBEROBN), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1469-7793.2001.00333.x","article-title":"Muscle damage from eccentric exercise: Mechanism, mechanical signs, adaptation and clinical applications","volume":"537","author":"Proske","year":"2001","journal-title":"J. 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